Clare M. Isacke, DPhil
Professor of Molecular Cell Biology
The Institute of Cancer Research
Professor Clare Isacke studied for her BA in biochemistry and DPhil in developmental biology with John Heath at the University of Oxford. She then moved to Tony Hunter and Ian Trowbridge's laboratories at the Salk Institute in San Diego to work on growth factor receptor signaling as a Damon Runyon postdoctoral fellow. On returning to England, she started her own research laboratory first in the Department of Biochemistry and then in the Department of Biology at Imperial College London. She was appointed professor of molecular cell biology in 2000. In 2001, Professor Isacke moved to The Institute of Cancer Research (ICR) in London to take up an appointment as professor of molecular cell biology in the Breakthrough Breast Cancer Research Centre.
Professor Isacke's laboratory focuses on uncovering the mechanisms by which tumor cells interact and communicate with their environment, in particular during the multiple steps of metastatic spread and tumour cell colonization of secondary sites.
In 2004, Professor Isacke was appointed deputy director of the Breakthrough Breast Cancer Research Centre and from 2011–2013 she was the interim director of the Breakthrough Breast Cancer Research Centre and the interim head of the Division of Breast Cancer Research. She is currently the acting head of the Division of Cancer Biology. In 2013, Professor Isacke was appointed academic dean at the ICR. Currently she chairs the Cancer Research UK (CRUK) New Investigator Awards committee, is a member of the CRUK Science Committee and is secretary-general of the European Association for Cancer Research (EACR).