Jen Jen Yeh, M.D., FACS, is an Associate Professor in the Division of Surgical Oncology and Departments of Surgery and Pharmacology at the University of North Carolina (UNC) at Chapel Hill. She established and directs the Patient-Derived Xenograft (PDX) Program at UNC.
Dr. Yeh received her B.A. from Wesleyan University. Prior to receiving her medical degree from the Johns Hopkins University School of Medicine, she worked in the laboratory of Dr. William G. Kaelin, Jr. After completing a general surgery residency at Boston Medical Center, during which she was a post-doctoral fellow in the laboratories of Dr. Charis Eng and Dr. William R. Sellers, she went on to become a surgical oncology fellow at the Memorial-Sloan Kettering Cancer Center. After joining the faculty at UNC in 2005, she worked in the laboratory of Dr. Channing Der until 2008 while establishing herself as an independent investigator.
Currently, in addition to an active surgical oncology practice that focuses on the care of patients with endocrine and pancreatic cancers, Dr. Yeh has devoted her research interests to focus on identifying key proteins that explain why and how pancreatic cancers metastasize. She has taken on a multidisciplinary approach (biomedical engineering, chemistry, genomics, proteomics, biostatistics) to tackle the complexities of pancreatic cancer and has established an infrastructure for the preclinical evaluation of therapeutic agents with the long-term goal of identifying promising therapies for pancreatic cancer and accelerating their translation to the clinic.