David A. Tuveson, MD, PhD
Director of Research, the Lustgarten Foundation Roy J. Zuckerberg Professor of Cancer Research
Cold Spring Harbor Laboratory
Cold Spring Harbor, New York
David Tuveson is professor and deputy director of the cancer center at Cold Spring Harbor Laboratory. Dr. Tuveson obtained a bachelor’s degree in chemistry at M.I.T. and medical and doctoral degrees at Johns Hopkins. Dr. Tuveson was a medical resident at Brigham and Women’s Hospital and a medical oncology fellow at Dana-Farber/Partners Cancer Care. During his postdoctoral years in Boston, Dr. Tuveson co-developed KIT inhibitors for gastrointestinal stromal tumors with George Demetri, and created several Kras dependent mouse cancer models with Tyler Jacks. His lab generated the first mouse models of ductal pancreatic cancer at the University of Pennsylvania, and subsequently moved to the University of Cambridge to develop preclinical and clinical therapeutic strategies for pancreatic cancer. In Cambridge, his lab identified a variety of parameters that limit therapeutic efficacy in pancreatic cancer, including poor drug delivery and survival factors in the microenvironment. These findings are currently undergoing clinical evaluation. Dr. Tuveson was recruited back to the USA to direct the Cancer Therapeutics Initiative at Cold Spring Harbor Laboratory and to serve as director of research for the Lustgarten Foundation. He will continue to practice medical oncology with an adjunct appointment at Memorial Sloan-Kettering Cancer Center. His honors include an award from the Rita Allen Foundation.