Steven J. Burakoff, M.D., is currently a professor of medicine, hematology/medical oncology, professor of oncological sciences, and the director of The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai. A native New Yorker, he graduated from Lehigh University with a Bachelor of Science degree, received his Master’s degree from Queens College, and his M.D. from Albany Medical College. Dr. Burakoff, who prior to his appointment in 2007 to Mount Sinai School of Medicine, was the Laura and Isaac Perlmutter professor at New York University School of Medicine, the director of the New York University Cancer Institute, and the director of the Skirball Institute of Biomolecular Medicine at the New York University School of Medicine from 2000 to 2007. Prior to joining the New York University School of Medicine, in 2000, he was chair of pediatric oncology at the Dana-Farber Cancer Institute and the Margaret M. Dyson professor of pediatrics at the Harvard Medical School, and also received an Honorary Master’s of Science degree from Harvard University. He was the recipient of the first Harvard Medical School Excellence in Mentoring Award. He was also the Ted Williams senior investigator at the Dana-Farber Cancer Institute, and he also served as a member of the Board of Trustees of the Dana-Farber Cancer Institute.
Dr. Burakoff serves as a member of the External Advisory Committee at the Cold Spring Harbor Laboratory Cancer Center and St. Jude Cancer Center. He is also on the Board of Directors of the Damon Runyon Cancer Research Foundation, as well as the Advisory Boards of the Starr Cancer Consortium and the Melanoma Research Alliance. Dr. Burakoff holds memberships in many professional societies and organizations, including: Alpha Omega Alpha, the American Society of Clinical Investigation, and the Association of American Physicians, and the American Association of Immunologist where he served as secretary-treasurer. He has been an editor and associate editor for numerous journals and author of more than 300 publications in peer-reviewed journals. In 2009, Dr. Burakoff received the American Association of Immunologists Lifetime Achievement Award. Also in 2009, Dr. Burakoff received the Lillian and Henry M. Stratton Professor of Cancer Medicine, an endowed professorship from the Mount Sinai School of Medicine.
Dr. Burakoff’s recent research interest is the study of signaling cascades that govern T-cell activation and regulate their functions, focusing research on signaling molecules and pathways that negatively regulate the effector functions of both CD4+ and CD8+ T cells. Finally, given their long-standing interest in CD4 function, Dr. Burakoff’s laboratory has recently turned its attention to studying the interaction of the HIV Nef protein with CD4.