Elizabeth M. Jaffee, M.D. is the Dana and Albert "Cubby" Broccoli professor of oncology and professor pathology at Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. After graduating magna cum laude from Brandeis University, Jaffee received her medical degree from New York Medical College. She completed her internship and residency at University of Pittsburgh, Presbyterian-University Hospital, then received a National Institutes of Health Research Training Grant as a research fellow and principal investigator at the University of Pittsburgh under the guidance of Fran Finn, Ph.D., research director. After that, Jaffee came to The Johns Hopkins University School of Medicine (JHUSOM) in Baltimore, Md., where she completed simultaneous fellowships as a senior clinical/research fellow in oncology and senior oncology fellow from 1989 – 1992. In 1992, Jaffee was appointed assistant professor of oncology at JHUSOM, as well as medical director of the Johns Hopkins Oncology Center Cell Processing and Gene Therapy cGMP Facility, a position she holds today. In 1995, Jaffee was appointed to a faculty position in the Graduate Program in Immunology. She holds a faculty position in the Graduate Program in Pharmacology and is a professor of oncology and a professor of pathology at JHUSOM.
Jaffee currently serves as co-director of the Gastrointestinal Cancers Program for JHUSOM and associate director for translational research for the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. She established and directs the Johns Hopkins Oncology Center Cell Processing and Gene Therapy cGMP Facility. In 2007, she was appointed deputy director for the Institute for Clinical and Translational Research at JHUSOM. She has also served as chair of the Clinical Research Committee at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and as a member of the National Cancer Institute (NCI) Board of Scientific Counselors and the RAID NCI Program Oversight Committee. In addition to her many Johns Hopkins administrative committee appointments, Jaffee is a member of the American Association for Cancer Research (AACR), American Society for the Advancement of Science, American Society of Clinical Oncology, American Association of Immunologists, and Society of Immunotherapy for Cancer.
Jaffee currently serves on the National Cancer Advisory Board. She is on the Board of Directors for the AACR, is a recent chair of the AACR Cancer Immunology Working Group (CIMM) Steering Committee, and is a member of the Cancer Vaccine Collaborative (CVC). She served as a co-organizer for the AACR Special Conference on Cancer Immunology in 2010 and 2012. Jaffee also serves on the Scientific Advisory Board of the Abramson Cancer Center at the University of Pennsylvania and on the External Advisory Boards of both the Seattle Cancer Consortium Breast SPORE and the University of Pittsburgh Cancer Institute Head and Neck Cancer SPORE. She has mentored 21 postdoctoral fellows and 12 graduate students, has over 130 peer-reviewed publications, and is a nationally and internationally recognized guest lecturer. Jaffee holds six vaccine patents, has been an investigator on many immunotherapy clinical studies, and has amassed millions of dollars in grants and sponsorships for the study of the immunotherapy of pancreatic cancer.