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FINDING CURES TOGETHER<sup>SM</sup>

Program

Daily Schedule - Friday - September 18

Meet the Editors
7:00 a.m.-8:00 a.m.

Cancer Immunology, Immunotherapy
Graham P. Pawelec, Editor-in-Chief
​Suzanne Ostrand-Rosenberg, Editor-in-Chief

Cancer Immunology Research
Robert D. Schreiber, Editor-in-Chief
Philip D. Greenberg, Editor-in-Chief
Linda J. Miller, Executive Editor

OncoImmunology
Guido Kroemer, Editor-in-Chief
Laurence Zitvogel, Editor-in-Chief
Lorenzo Galluzzi, Editor-in-Chief


Plenary Session 5: Immunotherapy of Persistent Viral Infections and Virus-1 Induced Cancers
Session Chairperson: Cornelis J.M. Melief, Leiden University Medical Center and ISA Pharmaceuticals BV, Leiden, The Netherlands  
8:00 a.m.-9:40 a.m.    

Chairperson perspective
Cornelis J.M. Melief

Properly timed chemo-immunotherapy of cancer
Sjoerd Henricus van der Burg, Leiden University Medical Center, Leiden, The Netherlands

Immunotherapy with virus-specific T cells
Helen Heslop, Baylor College of Medicine, Houston, Texas

T cell memory and exhaustion
Rafi Ahmed, Emory University, Atlanta, Georgia


Refreshment Break
9:40 a.m.-10:10 a.m.


Plenary Session 6: Biomarkers
Session Chairperson: Ira Mellman, Genentech, South San Francisco, California
10:10 a.m.-12:40 p.m.

Chairperson perspective: Biomarkers and mechanism in immunotherapy
Ira Mellman

Immune checkpoint therapy: Immune monitoring on presurgical and tissue-based clinical trials
Padmanee Sharma, The University of Texas MD Anderson Cancer Center, Houston, Texas

Antigenome and immune contexture in cancer
Jerome Galon, Cordeliers Research Center (INSERM), Paris, France

Genomic assessment of tumor immune profiles
Christian Ottensmeier, University of Southampton, Southampton, United Kingdom

Tumor-expressed IDO recruits and activates MDSCs in a Treg-dependent manner
Rikke B. Holmgaard, Memorial Sloan-Kettering Cancer Center, Ludwig Cancer Research, New York, New York


Imaging and Targeting of the Antitumor Response (Lunch provided)
12:40 p.m.-2:10 p.m.         

Immunological insights from tracking dynamic cellular behavior in lymph nodes and tissues
Alex Yee-Chen Huang, Case Western Reserve University School of Medicine, Cleveland, Ohio

Towards synthetic immune cells for cancer immunotherapy
Carl G. Figdor, Nijmegen Centre for Molecular Life Sciences (NCMLS), Nijmegen, The Netherlands

Imaging immunity: Creating a quantitative spatiotemporal understanding of host defense and anti-tumor responses
Ronald N. Germain, National Institute of Allergy and Infectious Disease, NIH, Bethesda, Maryland


General Lunch
12:40 p.m.-2:10 p.m.


Concurrent Sessions 1-2
2:25 p.m.-4:25 p.m.

Concurrent Session 1: Microbiome

Session Chairperson to be announced

Gut microbiota regulates anti-cancer immune responses 
Laurence Zitvogel, Gustave Roussy Cancer Center, Villejuif, France

Commensal microorganisms and polymorphic mucosal surfaces determine the evolution of distal metastatic tumors
Jose R. Conejo-Garcia, The Wistar Institute, Philadelphia, Pennsylvania

Biofilms, genetics and colon cancer
Cynthia L. Sears, Johns Hopkins University, Baltimore, Maryland

Tracking microbial sensing in colorectal cancer using bioorthogonal click chemistry*
Jason Hudak, Harvard Medical School, Boston, Massachusetts


Concurrent Session 2: Companion Diagnostics: Assay Harmonization
Session Chairperson: Axel Hoos, GlaxoSmithKline Pharmaceuticals, Collegeville, Pennsylvania

Introduction
Axel Hoos

Title to be announced
Abigail McElhinny, Ventana Medical Systems, Inc., Tucson, Arizona

Title to be announced
Robert A. Anders, Johns Hopkins University School of Medicine, Baltimore, Maryland

Title to be announced
Paul Tumeh, UCLA Medical Center, Los Angeles, California

Title to be announced
Kenneth Bloom, GE Healthcare, Aliso Viejo, California


Panel Discussion
3:45 p.m.-4:45 p.m.

Participants:

Robert A. Anders, Johns Hopkins University School of Medicine, Baltimore, Maryland

Kenneth Bloom, GE Healthcare, Aliso Viejo, California

Axel Hoos, GlaxoSmithKline Pharmaceuticals, Collegeville, Pennsylvania

Ian McCaffery, Genentech, South San Francisco, California

Abigail McElhinny, Ventana Medical Systems, Inc., Tucson, Arizona

Jim Novotny, Bristol-Myers Squibb, Princeton, New Jersey

Reena Philip, Food and Drug Administration Center for Devices and Radiological Health, Silver Spring, Maryland

Dave Stanforth, Dako North America - Agilent Technologies, Carpinteria, California

Paul Tumeh, UCLA Medical Center, Los Angeles, California


Poster Session B
4:45 p.m.-6:45 p.m.

*Short talks from proffered abstracts

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