Clara D. Bloomfield, MD

Clara D. Bloomfield, MD
​Distinguished University Professor; William G. Pace III Professor of Cancer Research; Cancer Scholar and Senior Advisor, The Ohio State University Comprehensive Cancer Center, James Cancer Hospital and Solove Research Institute, Columbus, Ohio

Clara D. Bloomfield, MD | Class of 2016

World renowned for her research involving chromosomal abnormalities and hematologic malignancies, Dr. Bloomfield has revolutionized the understanding of how genetic aberrations are capable of contributing to disease onset as well as influencing the efficacy of established treatment paradigms.

Her studies have resulted in the identification of the Philadelphia chromosome translocation in patients with acute lymphoblastic leukemia and similar aberrations such as inversions, deletions, and translocations involving 16q22 in acute myeloid leukemia.

Aside from studying the underlying genetic drivers of leukemia, Dr. Bloomfield’s research has also demonstrated that chemotherapies can be more efficacious if chosen based on the genetic characteristics of a patient’s specific cancer. She has proved that various subpopulations of patients respond differently to various types of treatments. Specifically, she demonstrated that some leukemia patients have higher remission rates following intensive chemotherapy, stem cell transplantation, or other treatment. This process of establishing patient-specific treatment regimens has and continues to produce significantly higher survival and disease-free rates for cancer patients.

Most recently, Dr. Bloomfield’s research efforts has centered on identifying new predictive biomarkers and classification techniques for acute myeloid leukemia and establishing new clinical guidelines for patients with various hematologic malignancies. Such guidelines are now directing which patients undergo gene, microRNA, and/or tumor expression profiling and also which precision medicine-based treatment approaches should be used.

Career Highlights

2016  Margaret L. Kripke Legend Award
2015  Giants of Cancer Care Award in Myeloid Neoplasms, OncLive
2014  Oncology Luminary, ASCO
2012  Richard L. Schilsky Cancer and Leukemia Group B Achievement Award
2011  Elected Fellow, American Academy of Arts and Sciences
2009  David A. Karnofsky Memorial Award and Lecture, ASCO
2008  Henry M. Stratton Medal, American Society of Hematology
2007  Emil Frei III Pioneer Award, The Leukemia and Lymphoma Society
2004  AACR-Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Cancer Research
2004  Elected Member, American Association of Physicians
2003  John P. Minton Hero of Hope Research Champion Medal of Honor Award, American Cancer Society
2000  Elected Member, Institute of Medicine of the National Academy of Sciences
1995-1998  Board of Directors, AACR
1995  Elected Fellow, American Association for the Advancement of Science
1968  MD, University of Chicago