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FINDING CURES TOGETHER<sup>SM</sup>
Allison S. Betof, MD, PhD

Chairperson-elect
Allison S. Betof, MD, PhD
Medical Oncology Fellow
Memorial Sloan Kettering Cancer Center
New York, New York

I graduated from the MD-PhD program at Duke and recently completed my Internal Medicine Residency at Massachusetts General Hospital. I am now a fellow in Medical Oncology at Memorial Sloan Kettering Cancer Center. My research focus is tumor microenvironment, angiogenesis, and drug delivery. My particular area of interest is on the effects of exercise on tumor microenvironment, including vascular structure, tumor-stroma interactions, tumor immunology, and metabolism. My ultimate goal is to apply these principles both in mouse models and clinical trials in order to understand the mechanisms by which exercise can modify the tumor microenvironment, and also to work with patients who may benefit from these advances.

My PhD research focused on the burgeoning field of cardio-oncology, exploring the effects of exercise on tumor angiogenesis and chemotherapeutic efficacy. Using murine models, we demonstrated that aerobic exercise slows breast tumor growth, improves tumor vessel structure and function, and augments the efficacy of cyclophosphamide chemotherapy. During my Internal Medicine residency at Massachusetts General Hospital, I pursued clinical research in order to prepare for a translational research career.

During my oncology fellowship and postdoctoral training, I will continue to focus on ways to therapeutically modify tumor angiogenesis and the microenvironment, both pharmacologically and using exercise in preclinical and clinical settings.

I became of an Associate Member of the AACR in 2013. I presented at the AACR Annual Meeting, and I was incredibly grateful for the opportunity to meet other likeminded scientists through the Associate Member Council, people who were willing to provide advice, guidance, and support. I’m thrilled to join the Council, and my primary goal is to strengthen the connection members feel to the AACR and enable early-career scientists to get the mentorship they need in order to flourish in this competitive environment.