American Association for Cancer Research

AACR Press Releases

Racial/Ethnic Disparities in Survival After Breast Cancer Remain Despite Similarities in Education, Neighborhood Socioeconomic Status


October 29, 2012

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  • Breast cancer survival is known to differ across racial/ethnic groups.
  • More education, better neighborhood socioeconomic status improved survival rates.
SAN DIEGO — Disparities in survival after breast cancer persisted across racial/ethnic groups even after researchers adjusted for multiple demographics, such as patients’ education and the socioeconomic status of the neighborhood in which they lived, according to data presented at the Fifth AACR Conference on The Science of Cancer Health Disparities, held here Oct. 27-30, 2012.

“We learned that the effects of neighborhood socioeconomic status differed by racial/ethnic group. When simultaneously accounting for race/ethnicity and socioeconomic status, we found persistent differences in survival within and across racial/ethnic groups,” said Salma Shariff-Marco, Ph.D., M.P.H., a researcher at the Cancer Prevention Institute of California in Fremont.

Shariff-Marco and colleagues studied data from 4,405 patients with breast cancer who had participated in one of two population-based studies undertaken in the San Francisco Bay Area. Participants included 1,068 non-Latina whites, 1,670 Latinas, 993 African-Americans and 674 Asian-Americans.

All-cause survival was worse for African-Americans and better for Latinas and Asian-Americans compared with non-Latina whites after adjusting for age, study and tumor characteristics. When the researchers additionally adjusted for treatment and reproductive and lifestyle factors, they found that African-Americans had similar survival rates to non-Latina whites, but the survival rates of Latinas and Asian-Americans remained better.

Researchers also evaluated disparities in survival while considering racial/ethnic and socioeconomic status interactions. Compared with non-Latina whites with high education and high neighborhood socioeconomic status, worse survival was seen for African-Americans with low neighborhood socioeconomic status (regardless of education) and better survival was seen among Latinas with high neighborhood socioeconomic status (regardless of education) and Asian-Americans with high education and high neighborhood socioeconomic status.

The researchers noted that certain groups who were identified as having better or worse survival would benefit from further study to understand their risk profiles and target specific interventions.

“Understanding and addressing potential barriers to better survival are needed for groups with worse survival,” Shariff-Marco said. “One program that may be useful is patient navigation to ensure that these women are able to access and navigate the health care system. Sharing these findings with the broader public health community (e.g., health educators, community-based organizations and leaders) will also be helpful.”

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About the American Association for Cancer Research
Founded in 1907, the American Association for Cancer Research (AACR) is the world’s first and largest professional organization dedicated to advancing cancer research and its mission to prevent and cure cancer. AACR membership includes more than 34,000 laboratory, translational and clinical researchers; population scientists; other health care professionals; and cancer advocates residing in more than 90 countries. The AACR marshals the full spectrum of expertise of the cancer community to accelerate progress in the prevention, biology, diagnosis and treatment of cancer by annually convening more than 20 conferences and educational workshops, the largest of which is the AACR Annual Meeting with more than 17,000 attendees. In addition, the AACR publishes seven peer-reviewed scientific journals and a magazine for cancer survivors, patients and their caregivers. The AACR funds meritorious research directly as well as in cooperation with numerous cancer organizations. As the scientific partner of Stand Up To Cancer, the AACR provides expert peer review, grants administration and scientific oversight of team science and individual grants in cancer research that have the potential for near-term patient benefit. The AACR actively communicates with legislators and policymakers about the value of cancer research and related biomedical science in saving lives from cancer.

For more information about the AACR, visit www.AACR.org.

Media Contact:
Jeremy Moore
(215) 446-7109
Jeremy.Moore@aacr.org
In San Diego, Oct. 27-30:
(619) 358-6870