The CTRC-AACR San Antonio Breast Cancer Symposium, Dec. 8-12, 2010, attracts world leaders in cancer research and treatment, including clinical oncologists, industry leaders, basic scientists and translational researchers who are working to improve patient care with the ultimate goal of eradicating breast cancer. Throughout the symposium, the following press briefings and interviews with researchers were conducted during which the researchers discussed the science presented at the meeting and other cancer research issues.
"Patient Screening and Management"
Thursday, Dec. 9, 2010, 8:00 a.m. CT
AACR President-elect Judy Garber, M.D., M.P.H., director of the Center for Cancer Genetics and Prevention at the Dana-Farber Cancer Institute, moderates this press conference.
"Results of the AZURE Trial"
Thursday, Dec. 9, 2010, 12:30 p.m. CT
Robert E. Coleman, M.D., professor and honorary consultant medical oncologist at the Cancer Research Center, Academic Unit Medical of Clinical Oncology at Weston Park Hospital in Sheffield, England, presents the results of the AZURE (Adjuvant Zoledronic Acid to Reduce Recurrence) trial at this press conference.
"Targeting HER2 Beyond Herceptin"
Friday, Dec. 10, 2010, 8:00 a.m. CT
Neil Spector, M.D., professor of medicine at Duke University Medical Center, hosts this press conference.
"Circulating Tumor Cells and Metastasis"
Friday, Dec. 10, 2010, 12:30 p.m. CT
Minetta Liu, M.D., director of translational breast cancer research at Georgetown Lombardi Comprehensive Cancer Center, a part of Georgetown University Medical Center, hosts this press conference.
SABCS 2010: Interview with Ivis Febus-Sampayo, director of LatinaSHARE, program at SHARE: Self-Help for Women with Breast or Ovarian Cancer
Ms. Febus-Sampayo discusses the cultural challenges faced by Latina women when they receive a cancer diagnosis, shares advice about how clinicians can best serve the Latina women who have cancer, and the long-term goals of her organization.
SABCS 2010: Interview with Carlos L. Arteaga, M.D., director of the Breast Cancer Program at Vanderbilt-Ingram Cancer Center, and professor of medicine and cancer biology at Vanderbilt University
Dr. Arteaga discusses targeted drugs for breast cancer, endocrine resistance, clinical trial enrollment criteria and his reactions to some of the important presentations at this year’s symposium.
SABCS 2010: Interview with Stacy L. Moulder, M.D., assistant professor of breast medical oncology at The University of Texas MD Anderson Cancer Center
Dr. Moulder talks about her research on PARP inhibitors for hard-to-treat breast cancers, such as triple-negative breast cancer, and the collaborative team that continues this line of research.
SABCS 2010: Interview with Chi Van Dang, M.D., Ph.D., professor of medicine, cell biology, oncology and pathology, the Johns Hopkins Family Professor and vice dean for research at Johns Hopkins University School of Medicine
Dr. Dang discusses the major points of his plenary session, "Oncogenic Reprogramming of Metabolism and Therapy," including how oncogenic alterations in cancers lead to altered tumor metabolism, and the function of the c-myc oncoprotein, which has emerged as a central oncogenic switch in breast and other cancers.
SABCS 2010: Interview with George W. Sledge Jr., M.D., professor of medicine at the Indiana University Simon Cancer Center, and recipient of the William L. McGuire Memorial Lecture Award
Dr. Sledge talks about his perspective on new therapies for breast cancer, and his goals as president of the American Society of Clinical Oncology.
SABCS 2010: Interview with Laura Esserman, M.D., M.B.A., director of the Carol Franc Breast Care Center and professor of surgery and radiology at the University of California, San Francisco
Dr. Esserman discusses her philosophy of holistic treatment and involving patients in the decision-making process, a cancer risk tracking system, and the I-Spy trials that match treatments to patients based on biomarkers.
SABCS 2010: Interview with Betty Anyanwu-Akeredolu, founder of the Breast Cancer Association of Nigeria
Ms. Anyanwu-Akeredolu discusses the challenges faced by women with breast cancer, the issues of raising awareness of breast cancer in Nigeria, and why she founded this advocacy organization.
SABCS 2010: Interview with Klaus Pantel, M.D., Ph.D., director of the Institute of Tumor Biology at the University Medical Center Hamburg-Eppendorf, and recipient of the 2010 AACR Outstanding Investigator Award for Breast Cancer Research
Dr. Pantel discusses his findings about micrometastasis that contradict long-held beliefs about metastasis, and the implications of these discoveries for the treatment of breast cancer.
SABCS 2010: Interview with Rowan T. Chlebowski, M.D., Ph.D., professor of medicine at the David Geffen School of Medicine at UCLA and chief of medical oncology and hematology at Harbor-UCLA Medical Center
Dr. Chlebowski, lead investigator for the Women’s Health Initiative, discusses the initiative’s findings about the use of hormone therapy and its influence on cancer incidence and related cancer mortality, and the effects of bisphosphonates on breast cancer risk.
SABCS 2010: Interview with Rochelle Shoretz, executive director of Sharsheret, a nonprofit organization dedicated to addressing the unique challenges facing young Jewish women with breast cancer
Ms. Shoretz talks about the mission of Sharsheret, how she came to establish this nonprofit organization, and her appointment to a federal advisory committee on breast cancer in young women.
SABCS 2010: Interview with Sandi Stanford, president of the Alamo Breast Cancer Foundation
Ms. Stanford talks about the mission of the Alamo Breast Cancer Foundation and how advocates can take an active role in breast cancer research.
SABCS 2010: Interview with Saraswati Sukumar, Ph.D., and Vered Stearns, M.D., co-directors of the breast cancer program at Johns Hopkins University School of Medicine
Drs. Sukumar and Stearns discuss clinical trials involving intraductal therapy as an alternative to surgery or radiation for ductal carcinoma in situ.
SABCS 2010: Interview with Edith A. Perez, M.D., deputy director of the Mayo Clinic Cancer Center in Jacksonville, Fla.
In this podcast, Dr. Perez discusses ALTTO (the Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization study), the role of genetic markers in breast cancer treatment, the challenges of treating patients with triple-negative breast cancer, and the promise of personalized medicine.
SABCS 2010: Interview with Charles M. Perou, Ph.D., professor of genetics, pathology and laboratory medicine at the University of North Carolina, Chapel Hill
Dr. Perou talks about genomic and genetic approaches to characterizing diverse breast cancers and their unique biologic features, using next-generation sequencing, and the implications of this science for clinical use.
SABCS 2010: Interview with Paul Workman, Ph.D., F.Med.Sci., professor of pharmacology and therapeutics director at Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, Sutton, UK
Dr. Workman defines molecular chaperones and discusses their role in the cell, stress response pathways, heat shock proteins and the potential of this line of breast cancer research.
SABCS 2010: Interview with Robert E. Coleman, M.D., professor of medical oncology, University of Sheffield, UK
Dr. Coleman, chief investigator of the AZURE (Adjuvant Zoledronic Acid to Reduce Recurrence) trial, presents the rationale for studying the bisphosphonate zoledronic acid, and the final results of this study.
SABCS 2010: Interview with Eric P. Winer, M.D., director of the Breast Oncology Center and Thompson senior investigator in breast cancer research at Dana-Farber Cancer Institute; professor of Medicine at Harvard Medical School
Dr. Winer discusses breast cancer screening, the clinical trials involving novel agents underway at Dana-Farber, and key advances in breast cancer research.
SABCS 2010: Interview with C. Kent Osborne, M.D., co-director of the SABCS and director of the Lester and Sue Smith Breast Center and the Dan L. Duncan Cancer Center at Baylor College of Medicine
Dr. Osborne talks about the most compelling research presented at the symposium this year, his long association with the SABCS and his vision for its future.
SABCS 2010: Interview with Jeffrey M. Rosen, Ph.D., the C.C. Bell professor of molecular and cellular biology at Baylor College of Medicine and the recipient of the 2010 Brinker Award for Scientific Distinction for basic science
Dr. Rosen discusses his research into the potential explanations for the relapse of many breast cancer patients who initially respond favorably to chemotherapy and radiation, and the next steps toward targeting breast cancer tumor initiating cells.
SABCS 2010: Interview with Amelie G. Ramirez, Dr.P.H., director of the Institute for Health Promotion Research and professor of epidemiology and biostatistics at the University of Texas Health Science Center at San Antonio; associate director of cancer health disparities at the Cancer Therapy Research Center in San Antonio
Dr. Ramirez discusses the importance of genetic testing for breast cancer among Latinas, statewide and national communications programs, challenges facing the Hispanic community in reference to cancer, and how to address some of these concerns.
SABCS 2010: Interview with Peter M. Ravdin, M.D., Ph.D., co-director of SABCS, director of the Comprehensive Breast Health Clinic at the Cancer Therapy and Research Center, University of Texas Health Science Center at San Antonio
Dr. Ravdin talks about his work with SABCS, notable abstracts being presented, and his vision for the future of the SABCS.
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Updated: Dec. 11, 2010