Previous opportunities are listed below to offer interested investigators an opportunity to view funding that may be offered again in the future. Details are subject to change.
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Previous Funding Opportunities for Independent Researchers
Previous Funding Opportunities for Independent Researchers
AACR Dharma Master Jiantai Innovative Grant for Lung Cancer Research
Program Mission Statement
The AACR Dharma Master Jiantai Innovative Grant for Lung Cancer Research will provide additional funding to an investigator for an existing project that develops and studies new ideas and approaches that have direct application and relevance to lung cancer. Following the Grant-in-Aid of Research model, this support supplements existing funding for an investigator conducting a basic or translational research project that will contribute to the acceleration of progress against lung cancer, for the ultimate goal of improving patient care.
The AACR Dharma Master Jiantai Innovative Grant for Lung Cancer Research is a one-year grant of $10,000 for research expenses, which may include supplemental salary support, equipment, research/laboratory supplies or relevant travel.
Interested applicants will be asked to submit a proposal of no more than three pages describing the existing lung cancer research project and the proposed use of the Jiantai Innovative Grant Funds.
It is anticipated that one grant will be funded.
Applicant Eligibility Criteria
Applicants must have a doctoral degree (including Ph.D., M.D., D.O., D.C., N.D., D.D.S., D.V.M., Sc.D., D.N.S., Pharm.D., or equivalent doctoral degree, or a combined clinical and research doctoral degree) in a related field and not currently be a candidate for a further doctoral or professional degree.
At the start of the grant term on July 1, 2013, applicants must:
- Hold a full-time faculty position with the title of instructor, research assistant professor, assistant professor or an equivalent full-time faculty position;
- Have held a full-time faculty position or the equivalent for no more than 10 years (i.e., cannot have had a full-time faculty appointment before July 2, 2003);
- Work at an academic, medical or research institution within the United States (There are no citizenship requirements; however, an applicant who is not a U.S. citizen or permanent resident, by submitting an application for this grant, assures that his/her visa status will provide sufficient time to complete the project and grant term within the United States.); and
- Currently be conducting a basic or translational research project that will contribute to the acceleration of progress against lung cancer.
Employees or subcontractors of a government entity or for-profit private industry are not eligible. Exceptions include applicants holding full-time positions at a veterans' hospital or national laboratory (e.g., Lawrence Berkeley National Laboratory) in the United States. Contact the AACR before submitting an application to determine your eligibility.
Both AACR members and nonmembers are eligible to apply. However, nonmembers must submit a satisfactory application for AACR active membership by November 22, 2012. The application will be applied to 2012 membership dues. Download a membership application.
Individuals may concurrently apply for other AACR grants; should an applicant apply for multiple AACR grants, he/she is expected to accept the first grant awarded. Individuals may accept and hold only one AACR Grant-in-Aid of Research grant at a time (but may hold other AACR grants).
Postdoctoral or clinical research fellows or the equivalent who are working under the auspices of a scientific mentor are not eligible to apply. Qualified fellows are invited to apply for an AACR Fellowship.
All applicants with questions about eligibility should contact AACR before submitting an application.
Program Guidelines and Application Instructions
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AACR-Kure It Grant for Kidney Cancer Research
Program Summary
The AACR-Kure It Grant for Kidney Cancer Research represents a joint effort to promote and support innovative cancer research. This grant is available to independent investigators to develop and study new ideas and approaches that have direct application and relevance to kidney cancer patients.
Applications are invited from researchers currently in the field as well as from investigators with experience in other areas of cancer research who have promising ideas or research approaches that can be applied to kidney cancer research. This grant will support an innovative translational research project designed to improve the survival and quality of life of patients with kidney cancer and lead to individualized therapeutic options for treatment or the development of promising new cancer therapeutics for kidney cancer. Emphasis will be placed on proposed projects which will translate into clinical applications within a few year period.
This 2-year grant provides $250,000 over the grant term ($125,000 per year). Grant funds support direct research expenses, which may include the salary and benefits of the grant recipient, and any collaborators (grant recipient/collaborator salaries limited to 25% of the total grant), postdoctoral or clinical research fellows and/or research assistants, equipment, travel, supplies, and indirect costs. It is anticipated that one grant will be funded.
Applicant Eligibility Criteria
Applicants must have a doctoral degree (including Ph.D., M.D., D.O., D.C., N.D., D.D.S., D.V.M., Sc.D., D.N.S., Pharm.D., or equivalent doctoral degree, or a combined clinical and research doctoral degree) in a related field and not currently be a candidate for a further doctoral or professional degree.
Applications will be accepted from independent investigators who are affiliated with an academic, medical or research institution anywhere in the world. There are no citizenship or geographic requirements.
Employees or subcontractors of a government entity or for-profit private industry are not eligible. Exceptions include applicants holding full-time positions at a veterans' hospital or national laboratory (e.g., Lawrence Berkeley National Laboratory) in the United States. Contact AACR before submitting an application to determine your eligibility. Employees or subcontractors of a government entity or for-profit private industry may serve as Collaborators or Consultants, but no grant funds may be directed towards these individuals or their respective institutions.
Both AACR members and nonmembers are eligible to apply. However, nonmembers must submit a satisfactory application for AACR active membership by August 23, 2012. The application will be applied to 2012 membership dues. An application may be downloaded from the AACR website at www.aacr.org.
Any individual who currently holds an active AACR grant or a Kure It grant may not apply. Past grantees may apply if they complied with all progress and financial report requirements.
Individuals may concurrently apply for multiple AACR grants. However, applicants are expected to accept the first grant they are awarded. Individuals may accept and hold only one AACR grant at a time.
Postdoctoral or clinical research fellows or the equivalent who are working under the auspices of a scientific mentor are not eligible to apply. Qualified fellows are invited to apply for an AACR Fellowship.
Members of the Scientific Review Committee are not eligible for this grant.
All applicants with questions about eligibility should contact AACR before submitting an application.
Program Guidelines and Application Instructions
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BCRF-AACR Grants for Translational Breast Cancer Research
Program Mission Statement
The Breast Cancer Research Foundation-AACR Grants for Translational Breast Cancer Research were established in 2007 to provide support for innovative cancer research projects designed to accelerate the discovery, development and application of new agents to treat breast cancer and/or for pre-clinical research with direct therapeutic intent.
Applicant Eligibility Criteria
Independent investigators who are affiliated with any institution involved in cancer research, cancer medicine or cancer-related biomedical science anywhere in the world may apply. There are no geographic, national or residency status restrictions. Pre- and postdoctoral fellows, clinical research fellows or the equivalent, or other investigators who are working under the auspices of a scientific mentor are not eligible to apply.
Employees or subcontractors of a national government or the for-profit private industry are not eligible to serve as the principal investigator for the purpose of these grants. However, collaborations with such individuals are encouraged.
Members of the Scientific Review Committee are not eligible for these grants.
Applicants must have acquired a doctoral degree in a related field.
Both AACR members and nonmembers are eligible to apply. However, nonmembers must submit a satisfactory application for AACR active membership. Download an application.
Current recipients of any AACR grant are not eligible. That is, individuals may hold only one AACR grant at a time. Past AACR grantees who have failed to submit a final progress report or a final financial report may not apply until these reports have been provided.
Program Guidelines and Application Instructions
Generously Supported By:
The Breast Cancer Research Foundation
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Caring for Carcinoid Foundation-AACR Grant for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor Research
Program Summary
The Caring for Carcinoid Foundation-AACR Grant for Carcinoid Tumor and Pancreatic Neuroendocrine Tumor Research represents a joint effort to promote and support innovative cancer research. This grant is available to independent junior and senior investigators to develop and study new ideas and approaches that have direct application and relevance to carcinoid tumors or pancreatic neuroendocrine tumors. Proposed research may be in any discipline of basic, translational, clinical, or epidemiological cancer research.
Applications are invited from researchers currently in the field as well as from investigators with experience in other areas of cancer research who have promising ideas or research approaches that can be applied to carcinoid tumor and pancreatic neuroendocrine tumor research.
This grant provides $250,000 over two years ($125,000 per year) for direct research expenses, which may include the salary and benefits of the grant recipient, and any collaborators (grant recipient/collaborator salaries limited to 25 percent of the total grant), postdoctoral or clinical research fellows and/or research assistants, equipment, travel and research/laboratory supplies (indirect costs not permitted).
Applicant Eligibility Criteria
Applicants must have a doctoral degree (including Ph.D., M.D., D.O., D.C., N.D., D.D.S., D.V.M., Sc.D., D.N.S., Pharm.D., or equivalent doctoral degree, or a combined clinical and research doctoral degree) in a related field and not currently be a candidate for a further doctoral or professional degree.
Applications will be accepted from independent investigators at all levels who are affiliated with an academic, medical or research institution anywhere in the world. There are no citizenship or geographic requirements.
Employees or subcontractors of a government entity or for-profit private industry are not eligible. Employees or subcontractors of a government entity or for-profit private industry may serve as collaborators, but no grant funds may be directed towards these individuals or their respective institutions.
Both AACR members and nonmembers are eligible to apply. However, nonmembers must submit a satisfactory application for AACR Active membership. An application may be downloaded from the AACR website at www.aacr.org.
Any individual who currently holds an active AACR grant or a Caring for Carcinoid Foundation grant may not apply. Past grantees may apply if they complied with all progress and financial report requirements.
Individuals may concurrently apply for multiple AACR grants. However, applicants are expected to accept the first grant they are awarded. Individuals may accept and hold only one AACR grant at a time.
Postdoctoral or clinical research fellows or the equivalent who are working under the auspices of a scientific mentor are not eligible to apply. Qualified fellows are invited to apply for an AACR Fellowship. Members of the Scientific Review Committee are not eligible for this grant.
All applicants with questions about eligibility should contact AACR at grants@aacr.org before submitting an application.
Research Project Criteria
Proposals will be accepted for new ideas and innovative approaches that have direct application and relevance to carcinoid tumors and pancreatic neuroendocrine tumors. Proposed research projects can be in any discipline including basic, translational, clinical, or epidemiological cancer research.
Applications are invited from researchers currently in the field as well as from investigators with experience in other areas of cancer research who have promising ideas or research approaches that they will directly apply to carcinoid tumors or pancreatic neuroendocrine tumors. Investigators who have powerful experimental tools that will lead to a better understanding of neuroendocrine tumor biology, elucidate the mechanisms of currently available therapies in neuroendocrine tumors, and identify new treatment targets for carcinoid tumors or pancreatic neuroendocrine tumors are encouraged to apply. The applicability of the proposed project to carcinoid tumor or pancreatic neuroendocrine tumor research must be fully described. A track record of research in this specific field is not a requirement for funding.
The research priorities of the Caring for Carcinoid Foundation include a desire to equitably provide support for both carcinoid tumor and pancreatic neuroendocrine tumor research. Genomic, RNA and proteomic studies of carcinoid tumors and pancreatic neuroendocrine tumors that complement ongoing genome-wide sequencing efforts funded by Caring for Carcinoid Foundation will be considered, but submission of studies that are duplicative of projects currently funded by the Caring for Carcinoid Foundation (see www.caringforcarcinoid.org) should be avoided.
Program Guidelines and Letter of Intent Instructions
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Landon Foundation-AACR INNOVATOR Award for International Collaboration in Cancer Research
Program Summary
International research collaboration can successfully address the global health problem of cancer through access to unique populations and environments, shared resources, specialized expertise, new concepts and perspectives, innovative methodologies and/or emerging technologies. However, barriers to sustaining these collaborations exist, such as the lack of funding as well as the lack of sharing of knowledge about these important research partnerships. The Landon Foundation-AACR INNOVATOR Award for International Collaboration in Cancer Research was established to help overcome these barriers by providing funding to an existing collaboration for costs traditional grant mechanisms may not support and to raise the profile of the importance of collaboration to conquering the cancer problem. This support supplements existing funding for the collaboration and provides the means to facilitate travel and the sharing of knowledge that otherwise may have been difficult to achieve in the absence of this funding.
This award recognizes and supports highly meritorious research that is being conducted collaboratively by investigators in different countries around the world. The award provides $100,000 over two years ($50,000 per year) to support the salary and benefits of postdoctoral or clinical research fellows and/or research assistants, equipment, research/laboratory supplies, travel between the collaborators’ institutions relevant to the collaboration, training in new techniques that will benefit the collaboration, such as training received through a scholar exchange/visiting professor program, and presentations of research data at scientific meetings or through other means that will contribute to the dissemination of the scientific knowledge gained. It is anticipated that one grant will be funded.
Applicant Eligibility Criteria
Applicants must have a doctoral degree (including Ph.D., M.D., D.O., D.C., N.D., D.D.S., D.V.M., Sc.D., D.N.S., Pharm.D., or equivalent doctoral degree, or a combined clinical and research doctoral degree) in a related field and not currently be a candidate for a further doctoral or professional degree.
Applications will be accepted from two or more independent investigators working within an established international cancer research collaboration involving institutes in multiple countries. Proposals to initiate a collaborative project will not be accepted. Only one investigator per institution is to be identified as a collaborator.
The collaborators may be affiliated with any institution involved in cancer research, cancer medicine or cancer-related biomedical science anywhere in the world. There are no citizenship or geographical requirements.
Employees or subcontractors of a government entity or for-profit private industry are not eligible. Employees or subcontractors of a government entity or for-profit private industry may serve as collaborators, but no grant funds may be directed towards these individuals or their respective institutions.
Any individual who is a current recipient of an AACR grant may not apply. Past AACR grantees may apply if they complied with all progress and financial report requirements.
Individuals may concurrently apply for multiple AACR grants. However, applicants are expected to accept the first grant they are awarded. Individuals may accept and hold only one AACR grant at a time.
Postdoctoral or clinical research fellows or the equivalent who are working under the auspices of a scientific mentor are not eligible to apply. Qualified fellows are invited to apply for an AACR fellowship.
Members of the Scientific Review Committee are not eligible for these grants.
Collaboration Criteria
Applications will be accepted from the leaders of an established collaborative international cancer research project in any discipline of basic, clinical, translational, or epidemiological cancer research involving institutes in multiple countries. Only one investigator per institution is to be identified as a Collaborator. Applications must demonstrate the collaboration’s utilization of unique populations and environments, shared resources, specialized expertise, new concepts and perspectives, innovative methodologies, and/or emerging technologies within a cancer research project.
Program Guidelines and Application Instructions
Generously Supported By: The Kirk A. and Dorothy P. Landon Foundation
The Kirk A. and Dorothy P. Landon Foundation was created through a bequest from Mrs. Dorothy P. Landon whose intent, along with that of her late husband, Kirk A. Landon, was to dedicate a major portion of their estate to medical research, especially research related to cancer. Mr. R. Kirk Landon, son of Kirk A. Landon, serves as the president of the foundation. The foundation seeks to accomplish its cancer research mission through a variety of programs and initiatives, including the Landon-AACR prizes and the Landon-AACR INNOVATOR awards.
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Landon Foundation-AACR INNOVATOR Award for Research in Personalized Cancer Medicine
Program Summary
The use of genomics to accurately predict individual responses to treatment with a drug or biologic agent is a central component of the future of personalized cancer medicine. This exciting direction in cancer treatment is the result of the discovery and elucidation of the molecular basis of cancer and involves understanding the risks and the responses that are associated with individual molecular differences. In this regard, there is a growing need not only to be able to predict which patients will respond to a particular treatment, but also who are likely to be the non-responders. The Landon Foundation-AACR INNOVATOR Award for Research in Personalized Cancer Medicine represents a joint effort between the Kirk A. and Dorothy P. Landon Foundation (Landon Foundation) and the American Association for Cancer Research (AACR) to accelerate progress in this area by providing support for physician-scientists who conduct meritorious studies with direct human therapeutic relevance.
Such studies may include proof-of-concept studies in humans; translational clinical trials that utilize science-based methodologies for patient selection; multidisciplinary research that includes the incorporation of disciplines that are new to cancer research, i.e., the physical sciences, mathematics, etc.; studies that molecularly target pathways; the identification of genes and genetic variations that play a role in cancer treatment responses; and other innovative areas of cancer therapeutics.
Applicants must be working in a multidisciplinary environment where collaborations are strongly encouraged, must have evidence of an established research program, and must plan to contribute significant time, effort and leadership to this project. This grant to physician-scientists is intended to have an impact on the field of personalized cancer medicine as a whole.
The award provides $100,000 over two years ($50,000 per year) for direct research expenses; which may include the salary and benefits of the grant recipient, postdoctoral or clinical research fellows, and/or research assistants, research/laboratory supplies, equipment and for attendance at AACR Annual Meetings, or other AACR meetings for the purpose of participating in scholarly exchange about the funded research.
It is anticipated that one grant will be funded.
Applicant Eligibility Criteria
Applicants must have a medical degree (M.D., D.O., or international equivalent) or hold a combined M.D./Ph.D. and not currently be a candidate for a further doctoral or professional degree.
At the start of the grant term applicants must:
- Hold a full-time faculty position with the title of instructor, research assistant professor, assistant professor or an equivalent full-time faculty position;
- Have held a full-time faculty position or the equivalent for no more than 10 years (i.e., cannot have had a full-time faculty appointment before July 2, 2003); and
- Work at an academic, medical or research institution anywhere in the world. (There are no citizenship or geographic requirements.)
Employees or subcontractors of a government entity or for-profit private industry are not eligible. Employees or subcontractors of a government entity or for-profit private industry may serve as collaborators, but no grant funds may be directed towards these individuals or their respective institutions.
Both AACR members and nonmembers are eligible to apply. However, nonmembers must submit a satisfactory application for AACR membership. An application may be downloaded from the AACR website at www.aacr.org.
Any individual who is a current recipient of an AACR grant may not apply. Past AACR grantees may apply if they complied with all progress and financial report requirements.
Individuals may concurrently apply for multiple AACR grants. However, applicants are expected to accept the first grant they are awarded. Individuals may accept and hold only one AACR grant at a time.
Postdoctoral or clinical research fellows or the equivalent who are working under the auspices of a scientific mentor are not eligible to apply. Qualified fellows are invited to apply for an AACR Fellowship.
Members of the Scientific Review Committee are not eligible for this grant.
Program Guidelines and Application Instructions
Generously Supported By: The Kirk A. and Dorothy P. Landon Foundation
The Kirk A. and Dorothy P. Landon Foundation was created through a bequest from Mrs. Dorothy P. Landon whose intent, along with that of her late husband, Kirk A. Landon, was to dedicate a major portion of their estate to medical research, especially research related to cancer. Mr. R. Kirk Landon, son of Kirk A. Landon, serves as the president of the foundation. The foundation seeks to accomplish its cancer research mission through a variety of programs and initiatives, including the Landon-AACR prizes and the Landon-AACR INNOVATOR awards.
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Pancreatic Cancer Action Network-AACR Innovative Grants
| Letter of Intent deadline: |
October 8, 2012, at noon Eastern Time |
| Applicants notified of LOI status: |
Early December 2012 |
| Application deadline (for those invited to apply): |
January 15, 2013, at noon Eastern Time |
| Decision date: |
March 2013 |
| Recognition event for recipients at the AACR Annual Meeting 2013: |
April 9, 2013 |
| Start of grant term: |
July 1, 2013 |
| Pancreatic Cancer Action Network Gala Weekend: |
October/November 2013 and October/November 2014 |
Program Summary
The Pancreatic Cancer Action Network-AACR Innovative Grants represent a joint effort to promote and support innovative pancreatic cancer research. They aim to spur creative and cutting-edge ideas and approaches in pancreatic cancer research, including those successful in other areas of cancer that have justifiable promise for pancreatic cancer. The research proposed for funding may be basic, translational, clinical or epidemiological in nature and must have direct applicability and relevance to pancreatic cancer.
These grants are available to full time, independent junior and senior investigators, including those with experience in other areas of cancer or biomedical/health science research who have promising ideas and approaches that can be applied to pancreatic cancer research.
The grants provide $200,000 over two years ($100,000 per year) for direct research expenses, which may include salary and benefits of postdoctoral or clinical research fellows, and/or research assistants; research/laboratory supplies; and equipment.
It is anticipated that multiple Innovative Grants will be funded.
Research Project Criteria
Proposals will be accepted for new ideas and innovative approaches that have direct application and relevance to pancreatic cancer. New ideas and innovative approaches may include, but are not limited to, those that utilize novel theoretical concepts, approaches or methodologies, instrumentation or interventions. Such concepts, approaches or methodologies, instrumentation or interventions may be novel to one field of research or novel in a broad sense, and/or may reflect a significant refinement, improvement or new application.
Proposals for innovative projects that will develop preliminary data necessary to prepare and submit a competitive research grant application to a major funding agency will be accepted.
Projects may be in any discipline of basic, clinical, translational or epidemiological research, and fall within at least one of the categories of the Common Scientific Outline (Biology; Etiology; Prevention; Early Detection, Diagnosis and Prognosis; Treatment; Cancer Control, Survivorship, and Outcomes Research; or Scientific Model Systems [https://www.icrpartnership.org/CSO.cfm]).
Applicant Eligibility Criteria
Applicants must have a medical and/or doctoral degree (including Ph.D., M.D., D.O., D.C., N.D., D.D.S., D.V.M., Sc.D., D.N.S., Pharm.D., or equivalent doctoral degree) in the biomedical sciences or in a field applicable to health science research and not currently be a candidate for a further doctoral or professional degree.
Submissions will be accepted from independent investigators at all levels who are affiliated with an academic, medical or research institution within the United States. There are no citizenship requirements; however, an applicant who is not a U.S. citizen or permanent resident, by submitting an application for this grant, assures that his/her visa status will provide sufficient time to complete the project and grant term within the United States.
Employees or subcontractors of a government entity or for-profit private industry are not eligible. Exceptions include applicants holding full-time positions at a veterans' hospital or national laboratory (e.g., Lawrence Berkeley National Laboratory) in the United States. Contact the AACR before submitting a Letter of Intent to determine your eligibility. Employees or subcontractors of a government entity or for-profit private industry may serve as collaborators, but no grant funds may be directed towards these individuals or their respective institutions.
Both AACR members and nonmembers are eligible to apply. However, nonmembers must submit a satisfactory application for AACR active membership by October 10, 2012. The application will be applied to 2012 membership dues. An application may be downloaded from the AACR website at www.aacr.org.
Any individual who currently holds an active AACR grant may not apply. Past grantees may apply if they complied with all progress and financial report requirements.
Investigators may submit only one Letter of Intent for a Pancreatic Cancer Action Network-AACR Innovative Grant, and may not apply for both a Pancreatic Cancer Action Network-AACR Innovative Grant and Pancreatic Cancer Action Network-AACR Career Development Award. Potential applicants eligible for both grant mechanisms are encouraged to review the guidelines to determine the more suitable one for which to apply.
Applicants for the Pancreatic Cancer Action Network–AACR Innovative Grants or Pancreatic Cancer Action Network–AACR Career Development Awards may also apply (or participate on a project team) for the Pancreatic Cancer Action Network-AACR Research Acceleration Network Grant. Individuals may also concurrently apply for other AACR grants; should an applicant apply for multiple AACR grants, he/she is expected to accept the first grant awarded.
Postdoctoral or clinical research fellows or the equivalent who will be working under the auspices of a scientific mentor at the beginning of the grant term (July 1, 2013) are only eligible to apply for the Pancreatic Cancer Action Network-AACR Fellowship (if in the first three years of postdoctoral or clinical research fellowship) or Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant (if in the first five years of postdoctoral or clinical research fellowship), but may also be part of a project team, though not as a co-PI, for the Pancreatic Cancer Action Network–AACR Research Acceleration Network Grant.
Members of the Scientific Review Committee are not eligible for these grants.
All applicants with questions about eligibility should contact the AACR before submitting a Letter of Intent.
Program Guidelines and Application Instructions
Generously Supported By
Pancreatic Cancer Action Network
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Pancreatic Cancer Action Network-AACR Research Acceleration Network Grant
| Letter of Intent deadline: |
October 8, 2012, at noon Eastern Time |
| Applicants notified of LOI status: |
Early December 2012 |
| Application deadline (for those invited to apply): |
January 15, 2013, at noon Eastern Time |
| Decision date: |
March 2013 |
| Recognition event for recipients at the AACR Annual Meeting 2013: |
April 9, 2013 |
| Start of grant term: |
July 1, 2013 |
| Pancreatic Cancer Action Network Gala Weekend: |
October/November 2013 and October/November 2014 |
Program Summary
The goal of the Pancreatic Cancer Action Network-AACR Research Acceleration Network (RAN) Grant is to provide funding and strategic assistance to a research project with the potential to double the survival rate from pancreatic cancer by the year 2020. The project must be implemented by a multi-institutional team and include a clinical component with an endpoint relevant to improving the detection or treatment of pancreatic cancer. The RAN Grant will provide $1,000,000 in funding over a one- to three-year time frame. In addition to the grant, the Pancreatic Cancer Action Network will provide strategic project management support to help optimize project implementation and progress during the grant term.
Research Project Criteria
The basis for the RAN Grant is the recognition that there is basic, translational, clinical and epidemiological research already underway within the pancreatic cancer community that provides a strong foundation and significant resources that could be brought to bear on the 2020 goal of doubling the survival rate for pancreatic cancer. The RAN Grant is designed to streamline and accelerate progress and effect the desired change in clinical outcome for this disease by linking synergistic capabilities, providing an efficient management structure, and providing funds that can be rapidly and strategically deployed. The project that is selected for a RAN Grant will leverage existing knowledge and experience and be milestone- and timeline-driven. The RAN Grant project must have a clinical component implemented at least by the third year of the funding period. It is recognized that the RAN Grant project is likely to represent a critical step in a longer-term project with a projected completion date of 2020, requiring clinical research beyond the budget and time scope of the RAN Grant. In this case, a plan that outlines the subsequent studies and feasibility of their completion should be provided to allow an assessment of the potential to reach the goal of doubling survival by 2020. Clinical impact, scientific validity and feasibility are overriding evaluation criteria in selecting the project to be funded by the RAN Grant.
The following scenarios are considered areas where there are sufficient developments within the pancreatic cancer field that could benefit from strategic acceleration. Note these are examples, and applications for the RAN Grant are not restricted to projects that conform to these scenarios:
- An immunotherapy approach that clinically tests combinations of a previously-tested vaccine with one or several immune modifying factors;
- Preclinical testing of rational combinations of chemotherapeutic agents currently in early phase clinical development and initial combination clinical trials. A plan is included for subsequent clinical testing of resulting promising combinations if this exceeds the time frame or budget of the RAN Grant;
- Neoadjuvant clinical study with tumor tissue for predictive and/or pharmacodynamic marker development;
- Adaptive clinical trial incorporating multiple targeted agents and predictive biomarkers;
- Clinical bioavailability studies for a promising imaging agent and the initiation of studies in a high-risk cohort;
- Large retrospective study with samples from multiple sites for an early detection or predictive serum biomarker panel with a feasible strategic plan for a prospective study (The prospective study may be outside of the RAN Grant budget or time frame but feasibly completed by 2020.).
Proposed RAN Grants must fall within at least one of the categories of the Common Scientific Outline (Biology; Etiology; Prevention; Early Detection, Diagnosis and Prognosis; Treatment; Cancer Control, Survivorship, and Outcomes Research; or Scientific Model Systems [https://www.icrpartnership.org/CSO.cfm]).
Applicant Eligibility Criteria
Two co-applicants serving as co-principal investigators (co-PIs) from distinct institutions are required. Additional co-PIs will be considered but their contribution must be well justified and add a critical perspective or role to the project. Principal investigators (PIs) must have a medical and/or doctoral degree (including Ph.D., M.D., D.O., D.C., N.D., D.D.S., D.V.M., Sc.D., D.N.S., Pharm.D., or equivalent doctoral degree) in the biomedical sciences or in a field applicable to health science research and not currently be a candidate for a further doctoral or professional degree.
The applicant designated as the contact PI must be a full time independent investigator affiliated with an academic, medical or research institution within the United States. Researchers holding full-time positions at a veterans' hospital are eligible to apply, and may be designated as the contact PI. Researchers holding full-time positions at a national laboratory (e.g., Lawrence Berkeley National Laboratory) in the United States may be eligible. Contact the AACR before submitting a Letter of Intent to determine your eligibility.
Past and current recipients of Pancreatic Cancer Action Network-AACR grants may apply for the RAN Grant if they complied with all progress and financial report requirements. Any individual who currently holds an active AACR grant not funded by the Pancreatic Cancer Action Network may not apply.
Only one Letter of Intent per contact PI will be accepted for the Pancreatic Cancer Action Network-AACR Research Acceleration Network, although individuals may serve as a co-PI or contribute to more than one Letter of Intent.
There are no citizenship requirements; however, an applicant who is not a U.S. citizen or permanent resident, by submitting an application for this grant, assures that his/her visa status will provide sufficient time to complete the project and grant term within the United States. Additional investigators from the named academic, medical or research institution(s) are eligible to contribute as co-PIs, project investigators or collaborators. Employees or subcontractors of a government entity or for-profit private industry are eligible to be project investigators or collaborators but cannot receive funding.
For further details, see “Additional Eligibility Requirements" below.
Program Guidelines and Application Instructions
Generously Supported By
Pancreatic Cancer Action Network
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Inquiries
Hanna Hopfinger, Program Associate
Telephone: (267) 646-0665
Fax: (215) 440-9372
Email:
grants@aacr.org