Forums

Assessing Response Using Imaging to Determine Endpoints in Clinical Trials

Lawrence H. Schwartz, Memorial Sloan-Kettering Cancer Center, New York, NY
Peter Choyke, National Cancer Institute, Bethesda, MD

Lung Cancer Screening Controversies: Does Every CT-Detected Lung Cancer Need Intervention?

David M. Jablons, University of California, San Francisco, CA
Peter P. Bach, Memorial Sloan-Kettering Cancer Center, New York, NY
Denise R. Aberle, UCLA David Geffen School of Medicine, Los Angeles, CA

Silencing Cancer? Potential and Obstacles for RNAi-Based Therapies

Judy Lieberman
Joshua Mendell, Johns Hopkins University, Baltimore, MD

Science Policy Forum
Beyond the HIPAA Privacy Rule

Women in Cancer Research Career Mentoring Forum

Keynote Speaker: Lynn M. Matrisian, Vanderbilt-Ingram Cancer Center, Nashville, TN

Mentors
• Suzanne A. Eccles, McElwain Laboratories, Sutton, Surrey, United Kingdom
• Ann D. Thor, University of Colorado Denver and Health Science Program, Aurora, CO
• Judith Campisi, Lawrence Berkeley National Laboratory, Berkeley, CA
• Julie Y. Djeu, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
• Judy E. Garber, Dana-Farber Cancer Institute, Boston, MA
• Elizabeth M. Jaffee, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD
• Patricia M. LoRusso, Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI
• Morag Park, Royal Victoria Hospital, Montréal, QC, Canada
• Beverly A. Teicher, Genzyme Corporation, Framingham, MA
• Patricia S. Steeg, National Cancer Institute, Bethesda, MD
• Lydia Armstrong, Novartis Pharmaceutical Corporation, Florham Park, NJ
• Elizabeth H. Blackburn, UCSF Mission Bay Campus, San Francisco, CA
• M. Anne Blackwood-Chirchir, Genentech, Inc., South San Francisco, CA
• Lynda Chin, Dana-Farber Cancer Institute, Boston, MA
• Suzanne D. Conzen, University of Chicago, Chicago, IL
• Joanna L. Groden, The Ohio State University, Columbus, OH
• Mien-Chie Hung, UT M. D. Anderson Cancer Center, Houston, TX
• Beverly D. Lyn-Cook, FDA-NCTR, Jefferson, AR
• Sonya D. Zabludoff, AstraZeneca R&D, Waltham, MA

MICR Forum: Preparing Junior Investigators for the Future: How to Use Career Development Awards Effectively

Shine Chang, UT M. D. Anderson Cancer Center, Houston, TX

Panelists
• Carlton R. Cooper, University of Delaware, Newark, DE
• Manuel Penichet, University of California, Los Angeles, CA
• Daniel C. Hughes, UT M. D. Anderson Cancer Center, Houston, TX

Cell-Cell Interactions in Angiogenesis

Luisa Iruela-Arispe, University of California, Los Angeles, CA
Ralf Adams, Max-Planck-Institute for Molecular Biomedicine, Münster, Germany

Genome-wide Scanning and Personalized Health: Where Is the Fit?

Jeffrey M. Trent, Translational Genomics Research Institute, Phoenix, AZ
David J. Hunter, Harvard University, Boston, MA

Immunological Therapy of Cancer: New Strategies and Clinical Endpoints

James C.Y. Yang, National Cancer Institute, Bethesda, MD
F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA

Molecular Biology in Early Phase Clinical Trials

Alex A. Adjei, Roswell Park Cancer Institute, Buffalo, NY
Michael R. Grever, The Ohio State University, Columbus, OH

Science Policy Forum
Cancer Drug Development as a Successful Public-Private Enterprise – The NCI in Partnership with Industry

Introduction and Opening Remarks
James A. Zwiebel

The NCI Developmental Therapeutics Program: From molecules to medicines
Jerry M. Collins, DCTD, National Cancer Institute, Rockville, MD

The NCI Cancer Therapy Evaluation Program: Therapeutics in the public interest
Jeffrey Abrams, National Cancer Institute, Rockville, MD

The NCI Cancer Imaging Program: Developing imaging tools for drug development
Paula Jacobs, DCTD, National Cancer Institute, Bethesda, MD

The NCI Experimental Therapy Program: Biomarker assay validation and Phase 0 trials
Joseph E. Tomaszewski, DCTD, National Cancer Institute, Bethesda, MD

Collaborative drug development with the NCI: An industry perspective
David P. Schenkein, Genentech, Inc., South San Francisco, CA

Panel Discussion
All speakers plus Michael R. Grever, The Ohio State University, Columbus, OH

Cancer Vaccines: Do They Work?

Elizabeth M. Jaffee, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD
Steven A. Rosenberg, National Cancer Institute, Bethesda, MD

Role of Free Radicals such as Reactive Oxygen Species (ROS) and Reactive Nitrogen Species (RNS) in Cancer Cell Signaling and Genomic Instability

Sankar Mitra, UT Medical Branch, Galveston, TX
Peng Huang, UT M. D. Anderson Cancer Center, Houston, TX

Targeting EGFR in Lung Cancer

Jeffrey A. Engelman, Massachusetts General Hospital, Charlestown, MA
Pasi A. Jänne, Dana-Farber Cancer Institute, Boston, MA

Therapeutic Targets and Breast Cancer Stem Cells

Monica L. Guzman, University of Rochester, Rochester, NY
Markus H. Frank, Children's Hospital Boston, Boston, MA

Science Policy Forum
Impact of the New Administration’s Priorities on Cancer Research

A New Paradigm for Understanding Excess Cancer Risk in Underserved and Minority Populations: The Centers for Population Health and Health Disparities Experience

Richard B. Warnecke, University of Illinois Cancer Center, Chicago, IL
Timothy R. Rebbeck, University of Pennsylvania School of Medicine, Philadelphia, PA
Sarah Gehlert, University of Chicago, Chicago, IL
Electra D. Paskett

Exploiting the Hypoxic Tumor Microenvironment for Therapeutics

Giovanni Melillo
Dietmar Siemann, University of Florida, Gainesville, FL
Albert C. Koong, Stanford University Medical Center, Stanford, CA
Amato J. Giaccia, Stanford University School of Medicine, Stanford, CA

Prostate Cancer: Latent versus Clinically Significant Disease: Does Every Cancer Need Intervention?

William J. Catalona, Northwestern University, Chicago, IL
Peter T. Scardino, Memorial Sloan-Kettering Cancer Center, New York, NY

Targeting the Rb Pathway in Cancer Therapy

Mariano Barbacid, National Cancer Center of Spain, Madrid, Spain
Erik S. Knudsen, University of Cincinnati, Cincinnati, OH

Cancer Stem Cells: Advances and Challenges

Carla Kim, Children’s Hospital Boston, Boston, MA
Yuan Zhu, University of Michigan Medical School, Ann Arbor, MI

Cancer Systems Biology: Fact or Fiction?

Allan Balmain, University of California Comprehensive Cancer Center, San Francisco, CA

New Views on Mammographic Density

Norman F. Boyd, Ontario Cancer Institute, Toronto, ON, Canada
Karla Kerlikowske, University of California, San Francisco, CA