American Association for Cancer Research

Annual Meeting 2012 Program: Educational Sessions

Sessions as of February 15

Educational Sessions

Advances in Chemoprevention
Chairperson: Powel H. Brown, The University of Texas MD Anderson Cancer Center, Houston, TX

  • Powel H. Brown
  • Patrick M. Lynch, The University of Texas MD Anderson Cancer Center, Houston, TX
  • Eva Szabo, National Cancer Institute, Potomac, MD
  • Ian M. Thompson, Jr., The University of Texas Health Science Center, San Antonio, TX

Androgen Receptors: Recent Advances in Targeting the Androgen Receptor for Prostate Cancer Prevention and Therapy
Chairperson: Steven P. Balk, Beth Israel Deaconess Medical Center, Boston, MA

  • Steven P. Balk
  • Peter S. Nelson, Fred Hutchinson Cancer Research Center, Seattle, WA
  • Marianne Sadar, BC Cancer Foundation, Vancouver, BC, Canada
  • Nancy Weigel, Baylor College of Medicine, Houston, TX

Antibody Engineering: Beyond Ehrlich’s Wildest Dreams
Chairperson: Hyam I. Levitsky, Hoffman-La Roche, Inc., Nutley, NJ

  • Patrick A. Baeuerle, Micromet Corporation, Munich, Germany
  • Hyam I. Levitsky
  • Gail Lewis Phillips, Genentech, Inc., South San Francisco, CA
  • Pablo Umana, Roche Glycart AG, Schlieren, Switzerland

Bench-to-Bedside Development of Next-Generation Immunotherapies
Chairperson: Larry W. Kwak, The University of Texas MD Anderson Cancer Center, Houston, TX

  • Larry W. Kwak
  • Yong-Jun Liu, The University of Texas MD Anderson Cancer Center, Houston, TX
  • Drew M. Pardoll, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD
  • Laurence Zitvogel, Institut Gustave-Roussy, Villejuif, France

Beyond GWAS: Genes, Environment, and Rare Variants
Chairperson: Ulrike Peters, Fred Hutchinson Cancer Research Center, Seattle, WA

  • Stacey Gabriel, Broad Institute of MIT and Harvard, Cambridge, MA
  • Carolyn M. Hutter, Fred Hutchinson Cancer Research Center, Seattle, WA
  • Peter L. Kraft, Harvard School of Public Health, Boston, MA
  • Cristen Willer, University of Michigan, Ann Arbor, MI

BRCA, Genomics, and Women’s Health: A Global Perspective
Chairperson: Olufunmilayo I. Olopade, University of Chicago Medical Center, Chicago, IL

  • Angela R. Bradbury, Fox Chase Cancer Center, Philadelphia, PA
  • Georgia Chenevix-Trench, Queensland Institute of Medical Research, Brisbane, Australia
  • Simon A. Gayther, University of Southern California, Los Angeles, CA
  • Jeffrey N. Weitzel, City of Hope, Duarte, CA

Cancer Immunology for the Non-Immunologist, Tutorial
Co-Chairpersons: Suzanne Ostrand-Rosenberg, University of Maryland, Baltimore, MD; and Olivera J. Finn, University of Pittsburgh School of Medicine, Pittsburgh, PA

  • Michael A. Caligiuri, The Ohio State University Comprehensive Cancer Center, Columbus, OH
  • Mario P. Colombo, Istituto Nazionale Tumori, Milan, Italy
  • Olivera J. Finn, University of Pittsburgh School of Medicine, Pittsburgh, PA
  • Bernard A. Fox, Earle A. Chiles Research Institute, Portland, OR
  • John G. Frelinger, University of Rochester Cancer Center, Rochester, NY
  • Hyam I. Levitsky, Hoffman-La Roche, Inc., Nutley, NJ
  • David M. Lubaroff, University of Iowa, Iowa City, IA
  • Francesco M. Marincola, National Cancer Institute, Bethesda, MD
  • Anna Karolina Palucka, Baylor University Medical Center, Dallas, TX
  • Gregory E. Plautz, The Cleveland Clinic, Cleveland, OH
  • Elizabeth A. Repasky, Roswell Park Cancer Institute, Buffalo, NY
  • Suzanne L. Topalian, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD
  • Louis M. Weiner, Georgetown Lombardi Comprehensive Cancer Center, Washington, DC
  • Weiping Zou, University of Michigan Medical School, Ann Arbor, MI

Cancer Signaling
Chairperson: Marcelo G. Kazanietz, University of Pennsylvania School of Medicine, Philadelphia, PA

  • Kerry L. Burnstein, University of Miami Miller School of Medicine, Miami, FL
  • Alan P. Fields, Mayo Clinic Florida, Jacksonville, FL
  • Marcelo G. Kazanietz
  • Alex Toker, Beth Israel Deaconess Medical Center, Boston, MA

Cancer Stem Cells: New Insights from New Approaches
Chairperson: Connie J. Eaves, BC Cancer Agency, Vancouver, BC, Canada

  • Hanno Glimm, National Center for Tumor Diseases, Heidelberg, Germany
  • R. Keith Humphries, University of British Columbia, Vancouver, BC, Canada
  • Carla F. Kim, Children's Hospital Boston, Boston, MA
  • Ali Turhan, Poitiers University Hospital, Poitiers, France

Cancer Survivorship: Role of Nutrition, Dietary Supplements, Physical Activity, and Weight Loss
Chairperson: Susan T. Mayne, Yale University School of Public Health, New Haven, CT

  • Wendy Demark-Wahnefried, University of Alabama at Birmingham, Birmingham, AL
  • Melinda L. Irwin, Yale University School of Public Health, New Haven, CT
  • Susan T. Mayne
  • Cheryl L. Rock, UCSD Moores Cancer Center, La Jolla, CA

Cancer Vaccines
Chairperson: Nina Bhardwaj, NYU School of Medicine, New York, NY

  • Carl G. Figdor, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands
  • Sacha Gnjatic, Memorial Sloan-Kettering Cancer Center, New York, NY
  • F. Stephen Hodi, Dana-Farber Cancer Institute, Boston, MA
  • Cornelis J.M. Melief, Leiden University Medical Center, Leiden, The Netherlands

Cell Cycle and Cancer
Chairperson: Piotr Sicinski, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA

  • Jiri Bartek, Danish Cancer Society, Copenhagen, Denmark
  • René H. Medema, UMC Utrecht Cancer Center, Utrecht, The Netherlands
  • Kei-Ichi Nakayama, Medical Institute of Bioregulation, Fukuoka, Japan
  • Terry L. Orr-Weaver, MIT Whitehead Institute for Biomedical Research, Cambridge, MA
  • Piotr Sicinski

Chemical Strategies for Modulating Protein-Protein Inhibition
Chairperson: James E. Bradner, Dana-Farber Cancer Inst., Boston, MA

  • Guowei Fang, Genentech, Inc., South San Francisco, CA
  • Stephen W. Fesik, Vanderbilt University School of Medicine, Nashville, TN
  • Jun Qi, Dana-Farber Cancer Institute, Boston, MA
  • Tomi Sawyer, Aileron Therapeutics, Cambridge, MA

Current Challenges in Molecular Marker Research
Chairperson: David F. Ransohoff, University of North Carolina, Chapel Hill, NC

  • Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI
  • Lisa M. McShane, National Cancer Institute, Bethesda, MD
  • David F. Ransohoff

Early Life Exposures in Cancer Etiology
Chairperson: Lawrence H. Kushi, Kaiser Permanente, Oakland, CA

  • Michele R. Forman, The University of Texas at Austin, Austin, TX
  • Randy L. Jirtle, Duke University Medical Center, Durham, NC
  • Lawrence H. Kushi
  • Cheryl Lyn Walker, The University of Texas MD Anderson Cancer Center, Smithville, TX

Established and Emerging Targets in Lung Cancer
Chairperson: Pasi A. Jänne, Dana-Farber Cancer Institute, Boston, MA

  • Trever G. Bivona, University of California, San Francisco, CA
  • Karen Cichowski, Brigham and Women's Hospital, Boston, MA
  • Peter S. Hammerman, Dana-Farber Cancer Institute, Boston, MA
  • Julien Sage, Stanford University School of Medicine, Stanford, CA

From Chemistry to the Clinic: Pathways for Drug Discovery and Development, Part 1: Targeting Tumor Heterogeneity with Novel Agent Combination Strategies
Chairperson: Matthew V. Lorenzi, Bristol-Myers Squibb Company, Princeton, NJ 

  • Channing J. Der, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC
  • Matthew V. Lorenzi
  • Richard L. Schilsky, University of Chicago, Chicago, IL
  • Jeffrey Settleman, Genentech, Inc., South San Francisco, CA

From Chemistry to the Clinic: Pathways for Drug Discovery and Development, Part 2: Challenges Validating New Targets for Cancer Drug Discovery
Chairperson: Dale A. Porter, Novartis Institutes for BioMedical Research, Cambridge, MA

  • C. Glenn Begley, Oxford BioTherapeutics, Inc., Westlake Village, CA
  • Dale A. Porter
  • Frank P. Stegmeier, Novartis Institutes for BioMedical Research, Acton, MA
  • Michael J. Zinda, AstraZeneca R&D Boston, Waltham, MA

From Chemistry to the Clinic: Pathways for Drug Discovery and Development, Part 3: Optimizing Drug Discovery: Insights on an Important Process
Chairperson: Michael J. Luzzio, Novartis Institutes for BioMedical Research, Cambridge, MA

  • John Flygare, Genentech, Inc., South San Francisco, CA
  • Robert L. Hoffman, Pfizer Global Research & Development, San Diego, CA
  • Michael J. Luzzio
  • Joseph P. Lyssikatos, Genentech, Inc., South San Francisco, CA
  • Michael Shultz, Novartis, Cambridge, MA

From Chemistry to the Clinic: Pathways for Drug Discovery and Development, Part 4: Chemical Development: Translating a Potent Agent into a Registered Product
Chairperson: Stephen A. Munk, Ash Stevens, Inc., Detroit, MI

  • David Mitchell, Eli Lilly and Company, Indianapolis, IN
  • Stephen A. Munk
  • Sanjeev Redkar, Astex Pharmaceutical Inc., Dublin, CA
  • Gita Shankar, SRI International, Menlo Park, CA

The Genetic Basis of Cancer Susceptibility: Molecular Testing to Clinical Surveillance
Chairperson: David Malkin, University of Toronto Hospital for Sick Children, Toronto, ON, Canada

  • David Malkin
  • Yael P. Mosse, Children's Hospital of Philadelphia, Philadelphia, PA
  • Joshua D. Schiffman, University of Utah Huntsman Cancer Institute, Salt Lake City, UT
  • Rosanna Weksberg, University of Toronto Hospital for Sick Children, Toronto, ON, Canada

The Hypoxic Tumor Microenvironment as a Target for Cancer Therapy
Chairperson: Giovanni Melillo, Bristol-Myers Squibb Co., Princeton, NJ

  • Juri G. Gelovani, The University of Texas MD Anderson Cancer Center, Houston, TX
  • Adrian L. Harris, University of Oxford, Oxford, United Kingdom
  • Giovanni Melillo
  • William Robert Wilson, University of Auckland Cancer Society Research Center, Auckland, New Zealand

Interrupting the PI3K-AKT-mTOR Pathway in Cancer Therapy
Chairperson: Steven Grant, VCU Massey Cancer Center, Richmond, VA

  • Phillip A. Dennis, National Cancer Institute, Bethesda, MD
  • Jeffrey A. Engelman, Massachusetts General Hospital, Boston, MA
  • Leonidas C. Platanias, Northwestern University Lurie Comprehensive Cancer Center, Chicago, IL
  • David B. Solit, Memorial Sloan-Kettering Cancer Center, New York, NY

Introduction to Interpretation of Clinical Trial Results: A Primer for Basic Scientists
Co-Chairpersons: Philippe L. Bedard, University of Toronto University Health Network, Toronto, ON, Canada; and Lee M. Ellis. The University of Texas MD Anderson Cancer Center, Houston, TX

  • Philippe L. Bedard
  • Lee M. Ellis
  • Mark J. Ratain, University of Chicago, Chicago, IL
  • Ian F. Tannock, University of Toronto University Health Network, Toronto, ON, Canada
  • Emile E. E. Voest, University Medical Center Utrecht, Utrecht, The Netherlands

Melanoma: Moving Beyond BRAF
Chairperson: Michael A. Davies, The University of Texas MD Anderson Cancer Center, Houston, TX

  • Boris C. Bastian, UCSF Cardiovascular Research Institute, San Francisco, CA
  • Michael A. Davies
  • Keiran S.M. Smalley, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
  • Scott Woodman, The University of Texas MD Anderson Cancer Center, Houston, TX

Molecular and Systems Pathology in Human Cancer: From Translational Research to Clinical Practice
Chairperson: Carlos Cordon-Cardo, Columbia University, New York, NY

  • Julide Tok Celebi, Columbia University, New York, NY
  • Carlos Cordon-Cardo
  • Janina A. Longtine, Brigham and Women's Hospital, Boston, MA
  • Ila Singh, Mount Sinai Medical Center, New York, NY

Molecular Mechanisms of Mature B-Cell Neoplasia
Chairperson: P. Lief Bergsagel, Mayo Clinic Arizona, Scottsdale, AZ

  • P. Lief Bergsagel
  • Riccardo Dalla-Favera, Columbia University Irving Comprehensive Cancer Center, New York, NY
  • Randy D. Gascoyne, BC Cancer Agency, Vancouver, BC, Canada
  • Sami N. Malek, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD

Myelodysplastic Syndromes: New Pathways and Treatment
Chairperson: Olivier Bernard, Institut Gustave-Roussy, Villejuif, France

  • Michaela Fontenay, Université Paris Descartes, Paris, France
  • Timothy Graubert, Washington University School of Medicine, St. Louis, MO
  • Seishi Ogawa, University of Tokyo, Bunkyo-Ku, Japan
  • David P. Steensma, Dana-Farber Cancer Institute, Boston, MA

Myeloid Cells and Immune Reprogramming in Solid Tumors: New Targets for Therapy
Chairperson: Lisa M. Coussens, Knight Cancer Institute, Oregon Health and Science University, Portland, OR

  • Michele De Palma, The Swiss Institute for Experimental Cancer Research, Swiss Federal Institute of Technology Lausanne, Lausanne, Switzerland
  • Luisa Iruela-Arispe, University of California, Los Angeles, CA
  • Anna Karolina Palucka, Baylor Institute for Immunology Research, Dallas, TX
  • Mikael J. Pittet, Massachusetts General Hospital, Boston, MA

Nonapoptotic Cell Death Mechanisms: Autophagy, Necroptosis, and Beyond
Chairperson: Guido Kroemer, INSERM U848, Institut Gustave-Roussy, Villejuif, France

  • Erik H. Baehrecke, University of Massachusetts Medical School, Worcester, MA
  • Simone Fulda, J.W. Goethe University of Frankfurt, Frankfurt, Germany
  • Guido Kroemer
  • Seamus J. Martin, Trinity College Dublin, Dublin, Ireland

Novel Targets in Hematologic Malignancies
Chairperson: Elizabeth A. Eklund, Northwestern University, Chicago, IL

  • Hetty E. Carraway, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD
  • Martin Carroll, University of Pennsylvania, Philadelphia, PA
  • Elizabeth A. Eklund
  • Jolanta Grembecka, University of Michigan, Ann Arbor, MI

Nuclear Receptors as Therapeutic Targets in Cancer
Chairperson: Donald P. McDonnell, Duke University Medical Center, Durham, NC

  • Orla M. Conneely, Baylor College of Medicine, Houston, TX
  • Vincent Giguère, McGill University Goodman Cancer Center, Montreal, QC, Canada
  • Carol Lange, University of Minnesota Masonic Cancer Center, Minneapolis, MN
  • John D. Minna, The University of Texas Southwestern Medical Center, Dallas, TX

Nutritionally Based Cancer Risk Reductive Interventions
Chairperson: Dean E. Brenner, University of Michigan Medical Center, Ann Arbor, MI

  • Dean E. Brenner
  • Stephen D. Hursting, University of Texas at Austin, Austin, TX
  • Madhuri Kakarala, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI
  • William P. Steward, University of Leicester, Leicester, United Kingdom

Prostate Cancer Mouse Models
Chairperson: Michael M. Shen, Columbia University, New York, NY

  • Brett S. Carver, Memorial Sloan-Kettering Cancer Center, New York, NY
  • Eva Corey, University of Washington, Seattle, WA
  • Simon W. Hayward, Vanderbilt University Medical Center, Nashville, TN
  • Michael M. Shen

The Role of Infectious Agents in Cancer
Chairperson: Larry Corey, Fred Hutchinson Cancer Research Center, Seattle, WA

  • Corey Casper, Fred Hutchinson Cancer Research Center, Seattle, WA
  • Stephen J. Polyak, University of Washington, Seattle, WA
  • Timothy R. Rebbeck, University of Pennsylvania School of Medicine, Philadelphia, PA
  • Sankar Swaminathan, University of Utah School of Medicine, Salt Lake City, UT

Targeting the Epigenome to Treat Cancer
Chairperson: Ricky W. Johnstone, Peter MacCallum Cancer Center, Melbourne, Australia

  • Robert A. Copeland, EpiZyme, Inc., Cambridge, MA
  • Mark A. Dawson, Cambridge Institute for Medical Research, Cambridge, United Kingdom
  • Ricky W. Johnstone
  • Johannes Zuber, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

Targeting the p53 Tumor Suppressor Pathway in Cancer Therapy
Chairperson: James J. Manfredi, Mt. Sinai School of Medicine, New York, NY

  • David P. Lane, A*STAR, Singapore
  • James J. Manfredi
  • Jennifer A. Pietenpol, Vanderbilt-Ingram Cancer Center, Nashville, TN
  • Lyubomir T. Vassilev, Hoffmann-La Roche, Inc., Nutley, NJ

Tumor Immunology for the Non-Immunologist
Chairperson: Hyam I. Levitsky, Hoffman-La Roche, Inc., Nutley, NJ

  • Wolf Hervé Fridman, Unité INSERM, Paris, France
  • Hyam I. Levitsky
  • Michel Sadelain, Memorial Sloan-Kettering Cancer Center, New York, NY
  • Eduardo M. Sotomayor, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL

Understanding Cancer Metabolism Pathways
Chairperson: Navdeep S. Chandel, Northwestern University, Chicago, IL

  • Ralph J. DeBerardinis, UT Southwestern Medical Center, Dallas, TX
  • Georgia Hatzivassiliou, Genentech, Inc., South San Francisco, CA
  • Nissim Hay, University of Illinois at Chicago, Chicago, IL
  • Matthew G. Vander Heiden, MIT Koch Institute for Integrated Cancer Research, Cambridge, MA


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