American Association for Cancer Research

Annual Meeting 2012 Program: Major Symposia

Sessions as of February 15

Major Symposia

AACR/ASCO Presidential Symposium – Learning from Our Children: New Insights in Pediatric Oncology
Co-Chairpersons: Judy E. Garber, AACR President, Dana-Farber Cancer Institute, Boston, MA; and Michael P. Link, ASCO President, Stanford University, Palo Alto, CA

  • Smita Bhatia, City of Hope, Duarte, CA
  • James R. Downing, St. Jude Children's Research Hospital, Memphis, TN
  • Judy E. Garber
  • Michael P. Link
  • Ching-Hon Pui, St. Jude Children's Research Hospital, Memphis, TN

Autophagy and Cancer
Chairperson: Eileen P. White, UMDNJ-The Cancer Institute of New Jersey, New Brunswick, NJ

  • Jun-Lin Guan, University of Michigan, Ann Arbor, MI
  • Kevin Ryan, Beatson Institute for Cancer Research, Glasgow, United Kingdom
  • Eileen P. White
  • Junying Yuan, Harvard Medical School, Boston, MA  

The Bayard D. Clarkson Symposium on Stem Cells and Cancer: Stem Cells, Self-Renewal, and Cancer
Chairperson: Sean J. Morrison, Children's Research Institute at UT Southwestern, Dallas, TX

  • Scott A. Armstrong, Children's Hospital Boston, Boston, MA
  • Ravindra Majeti, Stanford University, Stanford, CA
  • Sean J. Morrison
  • Benjamin G. Neel, Ontario Cancer Institute, Princess Margaret Hospital, Toronto, ON, Canada

Biologic Factors Associated With Cancer Disparities
Chairperson: Xifeng Wu, The University of Texas MD Anderson Cancer Center, Houston, TX

  • Adeyinka O. Laiyemo, National Cancer Institute, Bethesda, MD
  • Carol J. Etzel, The University of Texas MD Anderson Cancer Center, Houston, TX
  • Lisa A. Newman, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI
  • Peng Lee, New York University School of Medicine, New York, NY

Can Cancer Prevention Be Individualized?
Chairperson: Gad Rennert, CHS National Cancer Control Center, Haifa, Israel

  • Zvi Livneh, Weizmann Institute of Science, Rehovot, Israel
  • John Mathers, Human Nutrition Research Centre, Newcastle upon Tyne, United Kingdom
  • Gad Rennert
  • Margaret R. Spitz, The University of Texas MD Anderson Cancer Center, Houston, TX

Cell and Tissue Size Control in Cancer
Chairperson: John Blenis, Harvard Medical School, Boston, MA

  • Liliana Attisano, University of Toronto, Toronto, ON, Canada
  • John Blenis
  • Kun-Liang Liang Guan, UCSD Moores Cancer Center, La Jolla, CA
  • Brendan D. Manning, Harvard School of Public Health, Boston, MA

Chromatin and the Epigenome as Drug Targets
Chairperson: Cheryl Arrowsmith, University of Toronto Ontario Cancer Institute, Toronto, ON, Canada

  • Cheryl Arrowsmith
  • James E. Bradner, Dana-Farber Cancer Institute, Boston, MA
  • Dash Dhanak, GlaxoSmithKline, Collegeville, PA
  • Victoria M. Richon, Epizyme, Inc., Cambridge, MA

Clinical Trial Design in the Era of High-Density Data Analysis
Chairperson: Yu Shyr, Vanderbilt-Ingram Cancer Center, Nashville, TN

  • Tona M. Gilmer, GlaxoSmithKline, Research Triangle Park, NC
  • Yu Shyr
  • Lillian L. Siu, University Health Network Ontario Cancer Institute, Toronto, ON, Canada
  • Markus Warmuth, H3 Biomedicine, Inc., Cambridge, MA

Control of Metabolic Pathways and Cancer
Chairperson: Reuben J. Shaw, Salk Institute for Biological Studies, La Jolla, CA

  • Joan S. Brugge, Harvard Medical School, Boston, MA
  • Eyal Gottlieb, The Beatson Institute for Cancer Research, Glasgow, United Kingdom
  • Reuben J. Shaw
  • Craig B. Thompson, Memorial Sloan-Kettering Cancer Center, New York, NY

Designing Rational Combination Therapy for Cancer
Chairperson: Michael B. Yaffe, David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA

  • Douglas A. Lauffenburger, Massachusetts Institute of Technology, Cambridge, MA
  • Sylvia K. Plevritis, Stanford University, Stanford, CA
  • Brent R. Stockwell, Columbia University, New York, NY
  • Joshua M. Stuart, University of California, Santa Cruz, CA

Determining the Cell of Origin in Cancers
Chairperson: Jane E. Visvader, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia

  • Anton Berns, The Netherlands Cancer Institute, Amsterdam, The Netherlands
  • Cedric Blanpain, Université Libre de Bruxelles, Bruxelles, Belgium
  • Martine F. Roussel, St. Jude Children's Research Hospital, Memphis, TN
  • Jane E. Visvader

Developmental Pathways in Cancer
Chairperson: Jeffrey Wrana, University of Toronto, Toronto, ON, Canada

  • Frederic J. De Sauvage, Genentech, Inc., South San Francisco, CA
  • Senthil K. Muthuswamy, University of Toronto Ontario Cancer Institute, Toronto, ON, Canada
  • Jeremy Reiter, University of California, San Francisco, CA
  • Jeffrey Wrana

DNA Damage Repair and Cancer Therapy
Chairperson: Alan D. D’Andrea, Dana-Farber Cancer Institute, Boston, MA

  • Mary Helen Barcellos-Hoff, New York University, New York, NY
  • Alan D. D'Andrea
  • Andre Nussenzweig, National Cancer Institute, Bethesda, MD
  • Tanya T. Paull, University of Texas at Austin, Austin, TX

Dormant and Stem Cells in Tumor Heterogeneity
Chairperson: Jeffrey Settleman, Genentech, Inc., South San Francisco, CA

  • Julio A. Aguirre-Ghiso, Mount Sinai School of Medicine, New York, NY
  • Meenhard Herlyn, The Wistar Institute, Philadelphia, PA
  • Kornelia Polyak, Dana-Farber Cancer Institute, Boston, MA
  • Andreas Trumpp, Heidelberg Institute for Stem Cell Technology and Experimental Medicine, Heidelberg, Germany

Genetics and Epigenetics of Hematologic Malignancies
Chairperson: Olivier A. Bernard, Institut Gustave-Roussy, Villejuif, France

  • Olivier A. Bernard
  • Sai-Juan Chen, Shanghai Institute of Hematology, Shanghai, China
  • Brian Huntly, University of Cambridge, Cambridge, United Kingdom
  • Yue Xiong, University of North Carolina at Chapel Hill, Chapel Hil, NC

Genomic Integrity in Cancer
Chairperson: Karlene A. Cimprich, Stanford University, Stanford, CA

  • Angelika Amon, Massachusetts Institute of Technology, Cambridge, MA
  • Karlene A. Cimprich
  • Anindya Dutta, University of Virginia Health System, Charlottesville, VA
  • Óscar Fernández-Capetillo, Spanish National Cancer Research Center, Madrid, Spain
  • Jan Karlseder, Salk Institute for Biological Studies, La Jolla, CA

Genomics and Progression of Metastasis
Chairperson: Kari K. Alitalo, University of Helsinki, Helsinki, Finland

  • Kari K. Alitalo
  • Christine A. Iacobuzio-Donahue, Johns Hopkins Hospital, Baltimore, MD
  • Michael Karin, University of California San Diego, La Jolla, CA
  • Michael R. Stratton, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

Hypoxia: ROS and the Response to Therapy
Chairperson: M. Celeste Simon, Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA

  • Navdeep S. Chandel, Northwestern University, Chicago, IL
  • Amato J. Giaccia, Stanford University School of Medicine, Stanford, CA
  • Gregg L. Semenza, Johns Hopkins University, Baltimore, MD
  • M. Celeste Simon

Immune Cell Function and Cancer In Vivo: Visualizing Friends and Foes
Chairperson: Christopher H. Contag, Stanford University School of Medicine, Stanford, CA

  • John S. Condeelis, Sr., Albert Einstein College of Medicine, Bronx, NY
  • Christopher H. Contag
  • I. Jolanda M. De Vries, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands
  • Charles Lin, Massachusetts General Hospital, Boston, MA

Impact of Brain-Immune System Interactions on Cancer Development and Health-Related Quality of Life
Chairperson: Andrew Miller, Emory University, Atlanta, GA

  • Julienne Bower, UCLA Cousins Center for Psychoneuroimmunology, Los Angeles, CA
  • Firdaus S. Dhabhar, Stanford University, Stanford, CA
  • Andrew Miller
  • Leah M. Pyter, University of Illinois at Chicago, Chicago, IL

In Vivo Systems Biology: Modeling Regulatory Networks in the Mouse
Chairperson: Lynda Chin, The University of Texas MD Anderson Cancer Center, Houston, TX

  • David Adams, Wellcome Trust Sanger Institute, Cambridge, United Kingdom
  • Amy Brock, Harvard University, Brookline, MA
  • Lynda Chin
  • Tyler Jacks, David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA

Influence of Energy Balance and Obesity on Cancer Disparities:
The MICR Scientific Symposium
Co-Chairpersons: Christopher I. Li, Fred Hutchinson Cancer Research Center, Seattle, WA; and Amelie G. Ramirez, The University of Texas Health Science Center at San Antonio, San Antonio, TX

  • Wendy Demark-Wahnefried, The University of Texas MD Anderson Cancer Center, Houston, TX
  • Rong Li, The University of Texas Health Science Center at San Antonio, San Antonio, TX
  • Steven D. Mittelman, USC/Childrens Hospital Los Angeles, Los Angeles, CA
  • Kathryn H. Schmitz, University of Pennsylvania, Philadelphia, PA

Integrative Functional Genomics
Chairperson: William C. Hahn, Dana-Farber Cancer Institute, Boston MA

  • William C. Hahn
  • Michael T. Hemann, David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA
  • Scott W. Lowe, Memorial Sloan-Kettering Cancer Center, New York, NY
  • Jason Moffat, University of Toronto, Toronto, ON, Canada
  • Michael A. White, UT Southwestern Medical Center, Dallas, TX

Interrogating Antitumor Immunity
Chairperson: Pamela S. Ohashi, University of Toronto Ontario Cancer Institute, Toronto, ON, Canada

  • Jerome Galon, INSERM U255, Paris, France
  • Francesco M. Marincola, National Institutes of Health Clinical Center, Bethesda, MD
  • Pamela S. Ohashi
  • Jedd D. Wolchok, Memorial Sloan-Kettering Cancer Center, New York, NY

Interrogating the Logic of the Cancer Cell: Lessons From Integrative and Systems Biology Approaches
Chairperson: Douglas A. Lauffenburger, Massachusetts Institute of Technology, Cambridge, MA

  • Andrea Califano, Columbia University, New York, NY
  • Ernest Fraenkel, Massachusetts Institute of Technology, Cambridge, MA
  • Franziska Michor, Dana-Farber Cancer Institute, Boston, MA
  • Claire Tomlin, University of California, Berkeley, CA

Medicines Targeting Genetic Alterations
Chairperson: Nathanael S. Gray, Dana-Farber Cancer Institute, Boston, MA

  • Gideon Bollag, Plexxikon, Inc., Berkeley, CA
  • James G. Christensen, Pfizer, Inc., La Jolla, CA
  • Nathanael S. Gray
  • John Kuriyan, University of California, Berkeley, CA

Metastasis-Initiating Cells and Niches
Chairperson: Joan Massagué, Memorial Sloan-Kettering Cancer Center, New York, NY

  • Elaine V. Fuchs, Rockefeller University, New York, NY
  • Joan Massagué
  • David T. Scadden, Massachusetts General Hospital, Boston, MA
  • Ben Z. Stanger, Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA

Microbiome, Viruses, and Cancer
Chairperson: Anna R. Giuliano, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL

  • Martin J. Blaser, New York University Medical Center, New York, NY
  • Anna R. Giuliano
  • Allan Hildesheim, National Cancer Institute, Bethesda, MD
  • Julie Parsonnet, Stanford University School of Medicine, Stanford, CA

microRNAs and Cancer
Chairperson: Yibin Kang, Princeton University, Princeton, NJ

  • Thomas Brabletz, University of Freiburg, Frieburg, Germany
  • George A. Calin, The University of Texas MD Anderson Cancer Center, Houston, TX
  • Yibin Kang
  • Sohail Tavazoie, Rockefeller University, New York, NY

Modulating Antitumor Responses by Stromal Cells and Innate Immunity
Chairperson: Jeffrey W. Pollard, Albert Einstein College of Medicine, Bronx, NY

  • Nina Bhardwaj, New York University School of Medicine, New York, NY
  • Douglas T. Fearon, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom
  • Jeffrey W. Pollard
  • Robert H. Vonderheide, Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA

Molecular Imaging in Cancer Therapy: Functionalizing the Cancer Genome
Chairperson: David Piwnica-Worms, Washington University School of Medicine, St. Louis, MO

  • James P. Basilion, Case Western Reserve University, Cleveland, OH
  • Steven M. Larson, Memorial Sloan-Kettering Cancer Center, New York, NY
  • David Piwnica-Worms
  • Martin G. Pomper, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD

Mouse Models for Gene Discovery, Prevention, and Treatment
Chairperson: Guillermina Lozano, The University of Texas MD Anderson Cancer Center, Houston, TX

  • Cory Abate-Shen, Columbia University Irving Comprehensive Cancer Center, New York, NY
  • Guillermina Lozano
  • Owen J. Sansom, Beatson Institute for Cancer Research, Glasgow, United Kingdom
  • David A. Tuveson, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom

Nontraditional Targets of Small-Molecule Therapeutics: Emerging Technologies in the Post-Antibody Era
Chairperson: Hiroaki Suga, University of Tokyo, Tokyo, Japan

  • Anthony A. Kossiakoff, University of Chicago, Chicago, IL
  • Hiroaki Suga
  • Gregory L. Verdine, Harvard University, Cambridge, MA
  • Gregory Winter, Medical Research Council, Cambridge, United Kingdom

Pediatric Cancer Genomics: Honoring St. Jude Children’s Research Hospital’s 50th Anniversary
Chairperson: James R. Downing, St. Jude Children’s Research Hospital, Memphis, TN

  • John M. Maris, Children's Hospital of Philadelphia, Philadelphia, PA
  • Charles G. Mullighan, St. Jude Children's Research Hospital, Memphis, TN
  • Michael D. Taylor, University of Toronto Hospital for Sick Children, Toronto, ON, Canada
  • Jinghui Zhang, St. Jude Children's Research Hospital, Memphis, TN

Post-GWAS Functional Characterization of Cancer Risk Loci
Chairperson: Matthew L. Freedman, Dana-Farber Cancer Institute, Boston, MA

  • Stephen J. Chanock, National Cancer Institute, Bethesda, MD
  • Thomas J. Hudson, Ontario Institute for Cancer Research, Toronto, ON, Canada
  • Nazneen Rahman, Institute of Cancer Research, Sutton, United Kingdom
  • John Stamatoyannopoulos, University of Washington, Seattle, WA

Posttranslational Modifications in DNA Repair
Chairperson: Daniel Durocher, University of Toronto Ontario Cancer Institute, Toronto, ON, Canada

  • Daniel Durocher
  • Ronald T. Hay, University of Dundee, Dundee, United Kingdom
  • Helle Ulrich, Cancer Research UK London Research Institute, South Mimms, United Kingdom
  • Michael B. Yaffe, David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA

Protein Tyrosine Phosphatases and Cancer
Chairperson: Nicholas K. Tonks, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

  • Trever G. Bivona, University of California, San Francisco, CA
  • Nicholas K. Tonks
  • Thomas F. Westbrook, Baylor College of Medicine, Houston, TX
  • Wentain Yang, Brown University Alpert Medical School, Providence, RI

The Ras/Raf Pathway in Cancer
Chairperson: Deborah Morrison, National Cancer Institute, Frederick, MD

  • Christopher J. Marshall, Institute of Cancer Research, London, United Kingdom
  • Frank McCormick, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA
  • Deborah Morrison
  • Neal Rosen, Memorial Sloan-Kettering Cancer Center, New York, NY

The Ruth Sager Memorial Symposium on Cancer Genetics and Epigenetics: Chromatin, Transcriptional Regulation and Cancer
Chairperson: Trevor K. Archer, National Institute of Environmental Health Sciences, Research Triangle Park, NC

  • Trevor K. Archer
  • Myles Brown, Dana-Farber Cancer Institute, Boston, MA
  • Andrew P. Feinberg, Johns Hopkins University School of Medicine, Baltimore, MD
  • P. Andrew Futreal, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

Screening and Cancer Prevention in Underdeveloped Environments
Chairperson: Eduardo Cazap, Latin American and Caribbean Society of Medical Oncology (SLACOM), Buenos Aires, Argentina

  • Laurence H. Baker, University of Michigan, Ann Arbor, MI
  • Eduardo Cazap
  • Mei-Hwei Chang, National Taiwan University Hospital, Taipei, Taiwan
  • Surendra S. Shastri, Tata Memorial Hospital, Mumbai, India

The Stanley J. Korsmeyer Memorial Symposium: Programmed Necrosis
Chairperson: Douglas R. Green, St. Jude Children’s Research Hospital, Memphis, TN

  • Alexei Degterev, Tufts University School of Medicine, Boston, MA
  • Douglas R. Green
  • Peter Vandenabeele, University of Gent, Gent, Belgium
  • Xiaodong Wang, National Institute of Biological Sciences, Beijing, China

Stem Cells and Epigenetics
Chairperson: Bradley E. Bernstein, Massachusetts General Hospital, Boston, MA

  • Bradley E. Bernstein
  • Kristian Helin, University of Copenhagen, Copenhagen, Denmark
  • Alea A. Mills, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
  • Maarten Van Lohuizen, Netherlands Cancer Institute, Amsterdam, The Netherlands

Tumor Extracellular Matrix: An Emerging Target for Therapies
Chairperson: Richard O. Hynes, David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA

  • Richard O. Hynes
  • Ilaria Malanchi, Cancer Research UK London Research Institute, London, United Kingdom
  • Dario Neri, ETH Zürich, Zürich, Switzerland
  • Valerie M. Weaver, University of California Medical Center, San Francisco, CA

Vascular Reprogramming to Improve Clinical Outcome
Chairperson: Lena Claesson-Welsh, Uppsala University, Uppsala, Sweden

  • Lena Claesson-Welsh
  • Enrico Giraudo, Institute for Cancer Research and Treatment (IRCC), University of Turin, Candiolo, Italy
  • Donald M. McDonald, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA
  • Inder M. Verma, Salk Institute for Biological Studies, La Jolla, CA

Visualizing the Metabolic Environment of Tumors
Chairperson: Sarah J. Nelson, University of California, San Francisco, CA

  • Zaver M. Bhujwalla, Johns Hopkins University School of Medicine, Baltimore, MD
  • Murali Krishna Cherukuri, National Cancer Institute, Bethesda, MD
  • Kenneth A. Krohn, University of Washington, Seattle, WA
  • Sarah J. Nelson


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