Program

THURSDAY, SEPTEMBER 30

Educational Session 1
The Whether, How, and When of Race in Cancer Disparities Research: Three Viewpoints

Chairperson: Timothy R. Rebbeck, University of Pennsylvania School of Medicine, Philadelphia, PA
1:00 p.m.-3:00 p.m.

A social and ethical perspective
Vence Bonham, National Human Genome Research Institute, Bethesda, MD

A Native American community perspective
Judith S. Kaur, Mayo Clinic, Rochester, MN

An epidemiologist’s perspective
Timothy R. Rebbeck

Educational Session 2
The Chronic Disease Prevention Model: It's Time to Think Strategically

Chairperson: Elena Martinez, University of Arizona Cancer Center, Tucson, AZ
3:15 p.m.-5:15 p.m.

Strategic considerations in applying US-conceived models in cultures or settings other than those in which they were tested
Lawrence W. Green, University of California, San Francisco, CA

Vitamin D status as a measure of chronic disease risk
Elizabeth T. Jacobs, University of Arizona Cancer Center, Tucson, AZ

Addressing physical activity and obesity in the primary prevention of cancer
Antronette Yancey, University of California School of Public Health, Los Angeles, CA

Opening Plenary Session

7:00 p.m.-8:15 p.m.

Welcome and Opening Remarks
Margaret Foti, American Association for Cancer Research, Philadelphia, PA, and Levi A. Garraway, Dana-Farber Cancer Institute, Boston, MA

Special Video Presentation: Science Policy Evolves From Science

Keynote Address:
Money, maps, and mom: Fighting cancer in the 21st century
Arthur L. Kellermann, RAND Corporation, Arlington, VA

First AACR Distinguished Lecture on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved
Supported by a generous grant from Susan G. Komen for the Cure®
Charles M. Perou, University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC

Opening Reception

8:15 p.m.-10:15 p.m.

FRIDAY, OCTOBER 1

Continental Breakfast

6:30 a.m.-8:00 a.m.

Forum 1
How Can Science Drive Public Discourse to Impact Cancer Health Disparities?

Chairperson: Garth Graham, U.S. Department of Health and Human Services, Rockville, MD
7:00 a.m.-8:00 a.m.

An update on the implementation of the affordable care act and health disparities
Garth Graham

Where racial/ethnic populations are with respect to the cancer fight
Moon S. Chen, Jr., University of California Davis Cancer Center, Sacramento, CA

What's in a name: Health disparities or health equity? Is a new approach needed to engage America?
Lovell A. Jones, University of Texas MD Anderson Cancer Center, Houston, TX

Plenary Session 1
Blending Methodologies to Optimize Cancer Disparities Research

Chairperson: Rena J. Pasick, University of California Helen Diller Family Comprehensive Cancer Center, San Francisco, CA
8:00 a.m.-10:00 a.m.

The imperative of mixed methods for cancer disparities research
Rena J. Pasick

The methodologies of mixed methods research
Anthony Onwuegbuzie, Sam Houston State University, Huntsville, TX

Advancing racial and ethnic health disparities research through mixed-methods
Sheba George, Charles Drew University of Medicine and Science, Cerritos, CA

Contexts of clinical trials decision making: A multimethod approach
Nancy J. Burke, University of California, San Francisco, CA

View a summary of recent research in this area and relevant articles in AACR journals.

Break

10:00 a.m.-10:30 a.m.

Plenary Session 2
Prostate Cancer: Disparities in the Most Common Cancer in Men

Chairperson: William G. Nelson, Johns Hopkins Kimmel Comprehensive Cancer Center, Baltimore, MD
10:30 a.m.-12:30 p.m.

Race/ethnicity and inherited susceptibility to prostate cancer
Kathleen A. Cooney, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

Profiling of prostate tumors to identify factors that contribute to health disparities
Stefan Ambs, National Cancer Institute, Bethesda, MD

Disparities in screening and primary treatment for prostate cancer
Stephen J. Freedland, Duke University, Durham, NC

Disparities in treatment decision making watchful waiting/expectant management of indolent prostate cancer
Mack Roach, III, University of California Helen Diller Family Comprehensive Cancer Center, San Francisco, CA

View a summary of recent research in this area and relevant articles in AACR journals.

Lunch on own

12:30 p.m.-2:00 p.m.

Spotlight on Proffered Abstracts: Session 1

Chairperson: Levi A. Garraway, Dana-Farber Cancer Institute, Boston, MA
2:00 p.m.-3:00 p.m.

* Genetic African ancestry and race differences in blood Insulin-like growth Factor 1 (IGF-1), IGF-2, and IGF binding protein 3 (IGFBP-3)
Jay H. Fowke, Vanderbilt University, Nashville, TN

* Within-group differences between native-born and foreign-born Black men on prostate cancer risk reduction and early detection practices
Folakemi Odedina, University of Florida, Gainsville, FL

* CDX-2 polymorphism, calcium intake and prostate cancer risk for African-Americans in a population-based study
Glovioell Rowland, University of Southern California, Los Angeles, CA

* Genetic heterogeneity in colorectal cancer associations in African Americans
Nathan A. Ellis, University of Illinois, Chicago, IL

Plenary Session 3
Global Cancer Research and Training: Collaborating Internationally to Improve Health Outcomes

Co-Chairpersons: Silvia Franceschi, International Agency for Research on Cancer, Lyon, France; and Serigne M. Gueye, African Organization for Research and Training in Cancer, Dakar, Senegal
3:00 p.m.-5:00 p.m.

Introduction
Silvia Franceschi and Serigne M. Gueye

Differences in global cancer incidence, burden, outcome and future predictions
Silvia Franceschi

Defining standards of care and quality metrics in low-resource settings
Benjamin Anderson, Fred Hutchinson Cancer Research Center, Seattle, WA

Using a cancer prevention service infrastructure to foster the development of international research capacity initiatives: Lessons from Zambia
Groesbeck Parham, Center for Infectious Disease Research in Zambia (CIDRZ), Lusaka, Zambia

International clinical research - Barriers and challenges: A vision from independent and publicly funded trials
Eduardo Cazap, Latin American and Caribbean Society of Medical Oncology, Buenos Aires, Argentina

Cancer genetics in the African diaspora
Rick Kittles, University of Chicago, Chicago, IL

Building cancer research and training partnership that promote capacity building in Africa
Serigne M. Gueye

View a summary of recent research in this area and relevant articles in AACR journals.

Poster Session A / Reception

5:00 p.m.-7:00 p.m.

SATURDAY, OCTOBER 2

Continental Breakfast

6:30 a.m.-8:00 a.m.

Forum 2
Center to Reduce Cancer Health Disparities Funding Opportunities in Cancer Research and Training

Chairperson: Alexis Bakos, National Cancer Institute, Bethesda, MD
7:00 a.m.-8:00 a.m.

Key steps to success: The CURE diversity training program
Nelson H. Aguila, National Cancer Institute, Rockville, MD

Forging new steps to success: Opportunities in cancer health disparities
Carmen P. Moten, National Cancer Institute, Rockville, MD

Plenary Session 4
Emerging Technologies for Molecular Studies in Cancer

Chairperson: John D. Carpten, Translational Genomics Research Institute, Phoenix, AZ
8:00 a.m.-10:00 a.m.

Metabolomic profiling of cancer progression
Arun Sreekumar, Medical College of Georgia Cancer Center, Augusta, GA

Quantitative epigenomics for epidemiology research
Jean-Pierre J. Issa, University of Texas MD Anderson Cancer Center, Houston, TX

Title to be announced
John D. Carpten

View a summary of recent research in this area and relevant articles in AACR journals.

Spotlight on Proffered Abstracts: Session 2

Chairperson: Levi A. Garraway, Dana-Farber Cancer Institute, Boston, MA
10:00 a.m.-11:00 a.m.

* Risk factor distribution among women of Mexican descent by level of acculturation: Findings from the ELLA Binational Breast Cancer Study
Rachel L. Zenuk, University of Arizona, Mel and Enid Zuckerman College of Public Health, Tucson, AZ

* Does racial/ethnic concordance between patients and their navigators increase identification of barriers to care?
M. Christina Santana, Boston University School of Medicine, Boston, MA

* A church-based hepatitis B intervention for Korean Americans
Grace X. Ma, Temple University, Philadelphia, PA

* Gene-environment interactions between JAZF1 and occupational and neighborhood lead exposure in African American prostate cancer cases
Christine M. Neslund-Dudas, Henry Ford Hospital, Detroit, MI

Poster Session B / Reception

11:00 a.m.-1:00 p.m.

Special Session
A Novel Method to Recruit Minorities and the Medically Underserved for Research Studies

Chairperson: Susan M. Love, Dr. Susan Love Research Foundation, Santa Monica, CA
1:00 p.m.-2:00 p.m.

Panelists:

• Susan M. Love
• Vanessa B. Sheppard, Georgetown University Medical Center, Washington, DC
• Kristi D. Graves, Georgetown University, Washington, DC
• Ulrike Boehmer, Boston University School of Public Health, Boston, MA

The panel will focus on the Love/Avon Army of Women initiative and how it serves as a new approach for recruiting minorities and the medically underserved for translational research looking into the cause and prevention of breast cancer. Each panelist will focus on their experience using the Army of Women for their specific research study that required participation of racial/ethnic minorities and the medically underserved. Dr. Susan Love will discuss the overall vision for the initiative and some of the success stories. Drs. Sheppard, Graves, and Boehmer have used the Army of Women for their research studies, focusing on African-Americans, Latinas, and lesbian/bisexual women, respectively. They will discuss how this resource has accelerated their research and enabled them to save money, time, and resources. Supported by Love/Avon Army of Women

Plenary Session 5
Accrual and Retention of Minority and Underserved Populations: Moving Toward the Positive

Co-Chairpersons: Eddie Reed, University of South Alabama, Mobile, AL, and Bettye L. Green, Saint Joseph Regional Medical Center, South Bend, IN
2:00 p.m.-4:00 p.m.

The relevance of clinical trials to minorities
Sandra M. Underwood, University of Wisconsin, Milwaukee, WI

American College of Surgeons Oncology Group and cancer health disparities in clinical trials
David M. Ota, Duke University Medical Center, Durham, NC

Clinical trials, personalized medicine, and vulnerable patient populations
Christopher Lathan, Dana-Farber Cancer Institute, Boston, MA

It's time...are we ready? Looking at trial design, marketing, advocacy for enrollment, and retention of minority in clinic trials
Bettye L. Green

View a summary of recent research in this area and relevant articles in AACR journals.

Plenary Session 6
Emerging Molecular Determinants of Cancer Across Populations

Chairperson: Cheryl L. Willman, University of New Mexico Cancer Research and Treatment Center, Albuquerque, NM
4:15 p.m.-6:15 p.m.
Supported by Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine and UHealth - the University of Miami Health System

Discovery of novel genetic abnormalities and association with race and ethnicity in pediatric high-risk acute lymphoblastic leukemias
Cheryl L. Willman

Viral related malignancies affecting ethnic minorities and immigrant sub-populations in the U.S.
Juan C. Ramos, University of Miami Sylvester Comprehensive Cancer Center, Miami, FL

Title to be announced
Cosette M. Wheeler, University of New Mexico, Albuquerque, NM

View a summary of recent research in this area and relevant articles in AACR journals.

SUNDAY, OCTOBER 3

Continental Breakfast

6:30 a.m.-8:00 a.m.

Forum 3
Comparative Effectiveness Research in Health Disparities

Chairperson: Paul B. Jacobsen, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
7:00 a.m.-8:00 a.m.

Overview
Paul B. Jacobsen

The role of comparative effectiveness research in understanding and addressing disparities in cancer treatment
Deborah Schrag, Dana-Farber Cancer Institute, Boston, MA

Comparative effectiveness research and cancer health disparities as it relates to screening and early detection
Electra D. Paskett, Ohio State University Comprehensive Cancer Center, Columbus, OH

Plenary Session 7
Breast Cancer Disparities

Chairperson: Lisa L. Baumbach-Reardon, University of Miami Miller School of Medicine, Miami, FL
8:00 a.m.-10:15 a.m.

Overview of breast cancer disparities
Lisa A. Newman, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

Racial disparities in breast cancer: One size does not fit all
Erin N. Kobetz, University of Miami Miller School of Medicine, Miami, FL

The origin and evolution of patient navigation
Harold P. Freeman, Ralph Lauren Center for Cancer Care and Prevention, New York, NY

Genomic/genetic differences in breast cancer across ethnicities
Lisa L. Baumbach-Reardon

* Engaging immigrant Latinas in community-based interventions: Methods may be more important than messages for increasing screening
Deborah O. Erwin, Roswell Park Cancer Institute, Buffalo, NY

* Impact of race, ethnicity and health insurance on delays in breast cancer diagnosis in the District of Columbia
Heather J. Hoffman, George Washington University, Washington, DC

View a summary of recent research in this area and relevant articles in AACR journals.

Break

10:15 a.m.-10:30 a.m.

Plenary Session 8
Personalizing Cancer Prevention and Therapy

Chairperson: Alex A. Adjei, Roswell Park Cancer Institute, Buffalo, NY
10:30 a.m.-12:30 p.m.

Personalizing cancer therapy: Implications for health disparities
Alex A. Adjei

From genomics to personalized medicine in oncology
Levi A. Garraway, Dana-Farber Cancer Institute, Boston, MA

Race and cancer treatment outcome: Roswell Park over 50 years
James R. Marshall, Roswell Park Cancer Institute, Buffalo, NY

Title to be announced
Patricia A. Thompson, University of Arizona, Tucson, AZ

View a summary of recent research in this area and relevant articles in AACR journals.

Closing Remarks

12:30 p.m.-12:45 p.m.

Departure