Program

Sunday, September 18

Professional Advancement Series Session

Organized by AACR Minorities in Cancer Research (MICR)
Session Co-Chairpersons: Chanita Hughes-Halbert, Abramson Cancer Center of University of Pennsylvania, Philadelphia, PA, and Amelie G. Ramirez, University of Texas Health Science Center, San Antonio, TX
11:30 a.m.-1:00 p.m.

Panelists:
• Jasjit S. Ahluwalia, Center for Health Equity, University of Minnesota Medical School, Minneapolis, MN
• Shoba M. Amarnath, National Cancer Institute, Center for Cancer Research, Bethesda, MD
• Chanita Hughes-Halbert
• Rena J. Pasick, UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA

This informative Professional Advancement Series session will provide a forum in which students, postdoctoral candidates and junior investigators can discuss important career development issues, such as getting that first RO1, finding a good mentor and developing a research program, with established senior scientists. These topics will be addressed through a facilitated panel discussion. Although all conference attendees are invited to attend this session, it is geared toward early-career investigators. Advance registration is encouraged; onsite registration will be available on a first-come, first-served basis. Seating is limited.

Educational Session 1-2

1:00 p.m.-2:30 p.m.

• Biobanking: A Tricky Endeavor
  Session Chairperson: Peter G. Shields, Georgetown University Medical Center, Washington, DC

  Introduction
  Peter G. Shields
  
  Overview of biorepository best practices
  Jim Vaught, National Cancer Institute, Bethesda, MD

  Biospecimen management: Special considerations for minority populations
  Nicole Lockhart, National Cancer Institute, Bethesda, MD

  Collecting blood biospecimens from the Asian American communities through trust and informed consent
  Julie H.T. Dang, University of California Davis Cancer Center, Sacramento, CA

• How Do We Measure Disparities and Assess Progress?
  Session Chairperson: Sam Harper, McGill University, Montreal, QC, Canada

  Conceptual and methodological issues on measuring progress
  Sam Harper

  How we measure and track health disparities in the Healthy People 2010 Final Review
  Makram Talih, Center for Disease Control and Prevention, National Center for Health Statistics, Hyattsville, MD

  Measuring disparities by level of education and insurance status
  Elizabeth Ward, American Cancer Society, Atlanta, GA

Educational Sessions 3-4

2:45 p.m.-4:15 p.m.

• Epigenome: Tools and Technologies
  Session Chairperson: Bernard Kwabi-Addo, Howard University, Washington, DC

  Validation and quantitation of DNA methylation changes
  Bernard Kwabi-Addo

  Approaches for genome-wide analysis of DNA methylation
  Srinivasan Yegnasubramanian, Johns Hopkins University, Baltimore, MD

  Tools for analysis of genome-wide methylation data: An application to prostate cancer
  Joseph M. Devaney, George Washington University, Washington, DC

  Developing molecular markers for solid tumor detection and the promise of epigenetic therapy
  Malcolm V. Brock, Johns Hopkins University School of Medicine, Baltimore, MD

• Perspectives on Race: The RACE Project
  Session Chairperson: Yolanda Moses, University of California, Riverside, CA
  A project of the American Anthropological Association, this exhibit is currently on display at the Smithsonian National Museum of Natural History in Washington, DC

  Overview of The RACE Project
  Yolanda Moses

  Are we moving beyond "race" in clinical care?
  Vence L. Bonham, National Institutes of Health, Bethesda, MD

  Genetic variation among populations
  Kenneth K. Kidd, Yale University School of Medicine, New Haven, CT

  Perspectives on the production of race and cancer disparities
  Juliet McMullin, University of California, Riverside, CA

Dinner on own / Free time

4:15 p.m.-7:00 p.m.

Opening Plenary Session

7:00 p.m.-8:15 p.m.

Welcome
William G. Nelson, Johns Hopkins Kimmel Comprehensive Cancer Center, Baltimore, MD

Distinguished Lecture on the Science of Cancer Health Disparities
Supported by Susan G. Komen for the Cure®

Closing the knowledge disparity gap: From molecular mechanisms to interventions and back
Olufunmilayo I. Olopade, University of Chicago, Chicago, IL

• Learn more about Dr. Olopade's research

Opening Reception

8:15 p.m.-10:15 p.m.

Special musical entertainment: Julia Nixon

Monday, September 19

Continental Breakfast

7:00 a.m.-8:00 a.m.

Plenary Session 1: EBV and Cancer

Session Chairperson: Richard F. Ambinder, Johns Hopkins University, Baltimore, MD
8:00 a.m.-9:45 a.m.

New approaches to monitoring and treatment of EBV-associated malignancy
Richard F. Ambinder

The mechanism of Epstein-Barr virus persistent infection and the origins of associated lymphomas
David A. Thorley-Lawson, Tufts University, Boston, MA

Molecular patterns of endemic, sporadic and AIDS-related Burkitt’s lymphoma: Clues to distinct biology of subtypes
Sam M. Mbulaiteye, National Cancer Institute, Bethesda, MD

Potential for a vaccine approach to prevention of EBV-associated malignancy
Robert A. Baiocchi, Ohio State University, Columbus, OH

• View recent articles in AACR journals on EBV and cancer

Keynote Session

9:45 a.m.-10:45 a.m.

Towards a Future without Health Disparities
Louis W. Sullivan, former U.S. Secretary of Health and Human Services, and Founding Dean and First President of Morehouse School of Medicine, Atlanta, GA

Break

10:45 a.m.-11:00 a.m.

Plenary Session 2: Prevention of Liver Cancer: Induction of Aflatoxin Metabolism and Control of Hepatitis

Session Chairperson: John D. Groopman, Johns Hopkins University, Baltimore, MD
11:00 a.m.-12:45 p.m.

Global disparities and prevention strategies in liver cancer
John D. Groopman

Community-centered HBV/liver cancer control interventions for Asian Americans
Moon S. Chen, Jr., University of California Davis Cancer Center, Sacramento, CA

Hepatocellular carcinoma research and prevention in South Texas: The imperative *
Amelie G. Ramirez, University of Texas Health Science Center, San Antonio, TX

Genes, environment, and cancer
Curtis C. Harris, National Cancer Institute, Bethesda, MD

• View recent articles in AACR journals on liver cancer

Lunch on own / Free time

12:45 p.m.-2:00 p.m.

Plenary Session 3: Triple-Negative Breast Cancer in Young Underserved Women

Session Chairperson: Judy E. Garber, Dana-Farber Cancer Institute, Boston, MA
2:00 p.m.-3:45 p.m.

High-risk/triple negative breast cancer and African ancestry
Lisa A. Newman, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI

Biology of triple-negative breast cancer
James M. Ford, Stanford University, Stanford, CA

Treatment for triple-negative breast cancer: What's new?
Judy E. Garber

Warburg effect revisited: Glucose addition in precancerous mammary epithelial cells in African American women *
Victoria L. Seewaldt, Duke University, Durham, NC

• View recent articles in AACR journals on triple-negative breast cancer

Poster Session A

3:45 p.m.-6:15 p.m.

Dinner on own / Evening off

6:15 p.m.-

Tuesday, September 20

Continental Breakfast

7:00 a.m.-8:00 a.m.

Plenary Session 4: Cancer Screening: Multilevel Challenges in Vulnerable Populations

Session Chairperson: Stephen H. Taplin, National Cancer Institute, Bethesda, MD
8:00 a.m.-9:45 a.m.

Introduction: A multilevel perspective on cancer screening
Stephen H. Taplin, National Cancer Institute, Bethesda, MD

Efficacy of PSA screening for prostate cancer among elderly African Americans: A case-control study
Paul A. Godley, University of North Carolina, Chapel Hill, NC

Individuals and cancer screening: Family and community influences upon colorectal cancer screening in Arizona
Elena Martinez, University of Arizona, Tucson, AZ

Population impact: Using modeling to evaluate contributions of screening, treatment, and biology on disparities in breast cancer outcomes
Jeanne Mandelblatt, Georgetown Lombardi Comprehensive Cancer Center, Washington, DC

• View recent articles in AACR journals on cancer screening

Poster Session B

9:45 a.m.-12:15 p.m.

Lunch on own / Free time

12:15 p.m.-12:45 p.m.

Special Session
Increasing Recruitment of Minorities and the Medically Underserved for Research Studies

Presented by the Love/Avon Army of Women
Session Chairperson: Susan M. Love, Dr. Susan Love Research Foundation, Santa Monica, CA
12:45 p.m.-1:45 p.m.

Panelists:

• Susan M. Love
• Heather M. Ochs-Balcom, University at Buffalo, Buffalo, NY
• Kathleen F. Arcaro, University of Massachusetts, Amherst, MA
• Rosemarie Rogers, Army of Women Scientific Advisory Committee, Santa Monica, CA

Policy Forum 1: The Implementation of Health Care Reform: How Does it Address Health Disparities?

1:45 p.m.-2:45 p.m.

Caya B. Lewis, Chief of Staff, Centers for Medicare and Medicaid Services, Baltimore, MD; former Deputy Staff Director for Health for the U.S. Senate Health, Education, Labor, and Pensions Committee

Plenary Session 5: Tobacco: Still the Dominant Global Health and Disparities Threat

Session Chairperson: Roy S. Herbst, Yale Comprehensive Cancer Center, New Haven, CT
2:45 p.m.-4:30 p.m.

An overview of the global tobacco epidemic
Michele Bloch, National Cancer Institute, Rockville, MD

Tobacco use and cancer disparities: An AACR perspective
Roy S. Herbst

Tobacco-related disparities and the Family Smoking Prevention and Tobacco Act
Cathy Backinger, US Food and Drug Administration, Rockville, MD

Global tobacco inequalities: Role of communication, marketing, and promotion
K. Vish Viswanath, Dana-Farber Cancer Institute, Boston, MA

• View recent articles in AACR journals on tobacco and global health

Plenary Session 6: Patient Navigation in Cancer Care: Results from the Patient Navigation Research Program

Session Chairperson: Electra D. Paskett, Ohio State University, Columbus, OH
4:45 p.m.-6:30 p.m.

Introduction: Patient Navigation Research Program
Electra D. Paskett

Patient navigation and timeliness of diagnostic evaluation: Results for the Patient Navigation Research Program
Karen Freund, Boston University, Boston, MA

Effect of patient navigation on time from definitive diagnosis to initiation of treatment (T2) for breast, prostate, colorectal, and cervical cancers
Steven R. Patierno, George Washington University, Washington, DC, and
Peter C. Raich, University of Colorado, Denver, CO

Patient navigation and patient satisfaction with cancer-related care
Kevin Fiscella, University of Rochester, Rochester, NY

Effect of patient navigation on cost-effectiveness
Mark Bensink, Fred Hutchinson Cancer Research Center, Seattle, WA

Panel Discussion

• View recent articles in AACR journals on patient navigation in cancer care

Dinner on own / Evening off

6:30 p.m.-

Wednesday, September 21

Continental Breakfast

7:00 a.m.-8:00 a.m.

Plenary Session 7: Pharmacogenetics of Cancer Therapy: Challenges and Opportunities

Session Chairperson: Francis Ali-Osman, Duke University Comprehensive Cancer Center, Durham, NC
8:00 a.m.-9:45 a.m.

Linkage disequilibrium-based analysis of DNA repair and GST genes in malignant gliomas: A unique tool in defining the association between genetic diversity and survival
Francis Ali-Osman

Whole genome approaches to identify pharmacogenomic markers of anticancer agents
M. Eileen Dolan, University of Chicago, Chicago, IL

Ethnic differences and copy number imbalance in outcomes of early stage breast cancer
Patricia Thompson, Arizona Cancer Center, Tucson, AZ

• View recent articles in AACR journals on pharmacogenetics

Break

9:45 a.m.-10:00 a.m.

Policy Forum 2: Ensuring a Diverse Workforce of the Future

10:00 a.m.-11:00 a.m.

Participants:
• Douglas M. Garcia, Executive Director, Federal Relations and Outreach, Hispanic Association of Colleges and Universities (HACU), Washington, DC
• Valerie Montgomery Rice, Dean and Executive Vice President, Morehouse School of Medicine, Atlanta, GA

Plenary Session 8: Genomics and Epigenomics of Cancer Disparities

Session Chairperson: Steven R. Patierno, George Washington University, Washington, DC
11:00 a.m.-12:45 p.m.

Differential splicing of oncogenes and tumor suppressor genes between African and Caucasian Americans: Contributing factor in prostate cancer health disparities?
Norman H. Lee, George Washington University, Washington, DC

Fine mapping of genetic associations in African-American colorectal cancer
Nathan A. Ellis, University of Illinois, Chicago, IL

Disparities in vitamin D levels: Gene x environment interactions
Rick A. Kittles, University of Illinois, Chicago, IL

Exome sequencing of head and neck squamous cell carcinoma reveals a higher frequency of mutations in TP53 among African Americans *
Rafael Guerrero-Preston, Johns Hopkins School of Medicine, Baltimore, MD

• View recent articles in AACR journals on genomics and epigenomics

Closing Remarks

12:45 p.m.-1:00 p.m.

Departure