Session 1: Genes and Pathways in Cancer
Chairperson: Robert A. Weinberg, Whitehead Institute for Biomedical Research, Cambridge, MA
9:00 a.m.-12:00 p.m.
Molecular characterization of circulating tumor cells
Daniel A. Haber, Massachusetts General Hospital, Charlestown, MA
From chromosome engineering to chromatin remodeler: CHD5 is a tumor suppressor mapping to human 1p36
Alea A. Mills, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
New cancer targets emerging from studies of the VHL tumor suppressor gene
William G. Kaelin, Jr., Dana-Farber Cancer Institute, Boston, MA
PI3-Kinase and cancer metabolism
Lewis C. Cantley, Beth Israel Deaconess Medical Center, Boston, MA
Session 2: Mouse Models of Cancer
Chairperson: Guillermina Lozano, UT M. D. Anderson Cancer Center, Houston, TX
1:30 p.m.-3:45 p.m.
The regulation of p53 tumor suppressing activities
Studying tumor evolution in mouse models of cancer
Tyler E. Jacks, David H. Koch Institute for Integrative Cancer Research at MIT, Cambridge, MA
Dissecting tumor suppressor gene networks in vivo
Scott W. Lowe, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
Special Lecture: Epigenetics
Chairperson: Elizabeth H. Blackburn, University of California, San Francisco, CA
4:45 p.m.-5:30 p.m.
Cancer, stem cells, and the epigenetic terrain
Stephen B. Baylin, Johns Hopkins University School of Medicine, Baltimore, MD