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Hot Topics Breakfast Roundtable Session
7:00 a.m.-8:00 a.m.
We want to hear your ideas. Submit topics and discussion leaders to be considered for one of the roundtable discussions.
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Plenary Session 1
Epigenetics, Aging, and Environment
Chairperson: Dana Dolinoy, University of Michigan, Ann Arbor, MI
8:00 a.m.-10:00 a.m.
Environmental epigenetics: Novel approaches and insights
Dana Dolinoy
Epigenetics, aging, and cancer: From DNA methylation to microRNAs
Manel Esteller, Centro Nacional de Investigaciones Oncologicas (Spanish National Cancer Center), Barcelona, Spain
Tobacco, epigenetics, and lung and head and neck cancer risk
David Sidransky, Johns Hopkins University, Baltimore, MD
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Concurrent Sessions 1-3
10:15 a.m.-12:00 p.m.
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Session 1
Prostate Cancer: Controversies in Screening and Prevention
Chairperson: Eric A. Klein, Glickman Urological and Kidney Institute, Cleveland Clinic Lerner College of Medicine, Cleveland, OH
PSA screening: Benefit at what cost?
Ruth Etzioni, Fred Hutchinson Cancer Research Center, Seattle, WA
REDUCE trial
Gerald L. Andriole, Washington University School of Medicine, St. Louis, MO
SELECT trial
Eric A. Klein
*Vitamin D receptor expression is inversely associated with prostate cancer progression
Whitney Hendrickson, Harvard School of Public Health, Boston, MA
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Session 2
Novel Findings and Etiologic Hypotheses in Gynecologic Cancers
Chairperson: Roberta B. Ness, University of Texas School of Public Health, Houston, TX
Epigenetic targets in endometrial cancer
Karl C. Podratz, Mayo Clinic, Rochester, MN
Hopes and challenges for early detection of ovarian cancer
Kathy J. Helzlsouer, Mercy Medical Center, Baltimore, MD
Ovarian cancer epidemiology: Dusting off old ideas
Daniel W. Cramer, Harvard University, Boston, MA
*Dietary fat intake and risk of ovarian cancer in the NIH-AARP Diet and Health Study
Madeleine M. Blank, National Institutes of Health, National Cancer Institute, Rockville, MD
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Session 3
Future Directions of Tobacco Control: Science, Policy, and the FDA
Chairperson: Peter G. Shields, Lombardi Comprehensive Cancer Center at Georgetown University, Washington, DC
Assessing tobacco products to reduce harm
Peter G. Shields
Tobacco carcinogen and toxicant biomarkers
Stephen S. Hecht, Masonic Cancer Center, University of Minnesota, Minneapolis, MN
Reducing the nicotine content of cigarettes: Impact of smoking behavior and carcinogen exposure
Neal N. Benowitz, University of California San Francisco, San Francisco, CA
Integrating science and policy: Challenges for the FDA regulator
Matthew L. Myers, Campaign for Tobacco-Free Kids, Washington, DC
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Concurrent Sessions 4-6
1:15 p.m.-3:00 p.m.
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Session 4
Carcinogenesis and Biomarkers
Chairperson: Stephen J. Meltzer, Johns Hopkins University, Kimmel Comprehensive Cancer Center, Baltimore, MD
DNA methylation markers for colorectal cancer diagnosis
Yuriko Mori, Johns Hopkins University School of Medicine, Baltimore, MD
Esophageal cancer and the tumor microenvironment
Anil K. Rustgi, Abramson Cancer Center at University of Pennsylvania, Philadelphia, PA
Cancer predisposition: I say genetics, you say genomics, but are we there yet?
Charis Eng, The Cleveland Clinic, Cleveland, OH
*Genetic variations in microRNA biogenesis genes as predictors for risk of second primary tumor (SPT) and/or recurrence in patients with early-stage head and neck cancer
Xiaofan Zhang, UT M. D. Anderson Cancer Center, Houston, TX
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Session 5
Energy Balance: From the Bench to the Bedside and Community
Chairperson: Tim E. Byers, University of Colorado Cancer Center, Aurora, CO
Energy balance and cancer at the bench: What's new?
Henry J. Thompson, Colorado State University, Fort Collins, CO
Energy balance in cancer patients: Are we ready to intervene?
Pamela J. Goodwin, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada
Energy balance within the community: What's new?
Tim E. Byers
*Blood lipid and lipoprotein levels and the risk of colorectal cancer in the European prospective investigation into cancer and nutrition
Fränzel J. Van Duijnhoven, National Institutes for Public Health and Environment, Bilthoven, Netherlands
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Session 6
Optical Imaging
Co-Chairpersons: Frank G. Ondrey, University of Minnesota, Minneapolis, MN, and Thomas D. Wang, University of Michigan, Ann Arbor, MI
Introduction
Frank G. Ondrey
Optical coherence tomography imaging of preneoplastic lung lesion
Calum MacAulay, University of British Columbia, Vancouver, BC, Canada
The role of endoscopic ultrasound in the pancreas
Nuzhat A. Ahmad, University of Pennsylvania, Philadelphia, PA
Multimodal optical imaging for improved early detection of oral cancer and its precursors at the point of care
Rebecca Richards-Kortum, Rice University, Houston, TX
*Alterations in tissue autofluorescence using spectroscopy in high-risk oral lesions
Catherine F.Y. Poh, British Columbia Cancer Research Centre, University of British Columbia, Vancouver, BC, Canada
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Plenary Session 2
Preneoplasia: A Target for Cancer Chemoprevention
Chairperson: Gary D. Stoner, Ohio State University Comprehensive Cancer Center, Columbus, OH
3:15 p.m.-5:15 p.m.
Chemoprevention of preneoplastic lesions in the gastrointestinal tract
Gary D. Stoner
Insights from a new mouse model into the role of inflammation at early stages of lung carcinogenesis
Reuben Lotan, UT M. D. Anderson Cancer Center, Houston, TX
Molecular alterations that predict premalignancy in breast cancer
Thea D. Tlsty, University of California School of Medicine, San Francisco, CA
Targeting aberrant crypt foci for chemoprevention
Daniel W. Rosenberg, University of Connecticut Health Center, Farmington, CT
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AACR-Prevent Cancer Foundation Award for Excellence in Cancer Prevention Research Lecture
5:15 p.m.-6:15 p.m.
Biomarkers and cancer prevention: Cautionary lessons from the study of human papillomavirus and cervical cancer
Mark W. Schiffman, National Cancer Institute, Rockville, MD
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Behavioral Science Networking Event
6:00 p.m.-7:30 p.m.
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Poster Session A
6:15 p.m.-8:45 p.m.
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