American Association for Cancer Research

Cancer Epigenetics

January 20-23, 2010
Caribe Hilton
San Juan, Puerto Rico

CHAIRPERSONS:
Peter W. Laird, USC Epigenome Center, Los Angeles, CA
Jean-Pierre J. Issa, UT M. D. Anderson Cancer Center, Houston, TX
Kornelia Polyak, Dana-Farber Cancer Institute, Boston, MA

Information on registration, abstract submission, accommodations, etc. will be available in mid-2009.


Program as of June 19, 2009

WEDNESDAY, JANUARY 20, 2010

Keynote Address

7:00 p.m.-8:30 p.m.


Reprogramming of somatic cells to a pluripotent state
Rudolph Jaenisch, Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA

WELCOME RECEPTION

8:30 p.m.-9:30 p.m.

 

THURSDAY, JANUARY 21, 2010

Session 1: Epigenetics of Stemness and Differentiation

8:00 a.m.-10:00 a.m.


Epigenetic regulation of hematopoietic stem cells
Margaret A. Goodell, Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, TX

DNA methylation mapping in human leukemia
Alexander Meissner, Broad Institute of Harvard and MIT, Cambridge, MA

Title to be announced
Bing Ren, Ludwig Institute for Cancer Research, University of California, San Diego, CA

Session 2: Other Epigenomes

11:00 a.m.-1:00 p.m.


Cancer epigenomics
Peter A. Jones, USC/Norris Comprehensive Cancer Center, Los Angeles, CA

Chromatin assembly and disassembly
Jessica K. Tyler, University of Colorado Health Sciences Center, Denver, CO

Additional speaker to be announced

Poster Session A

4:00 p.m.-7:00 p.m.

Session 3: Readers and Writers

7:00 p.m.-9:00 p.m.


The role of histone methyltransferases and demethylases in stem cells and cancer
Kristian Helin, Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

TDRD3 is an effector molecule for CARM1-generated methylation motifs
Mark T. Bedford, UT M. D. Anderson Cancer Center, Smithville, TX

Title to be announced
Adrian Bird, Wellcome Trust Centre for Cell Biology, University of Edinburgh, Edinburgh, Scotland

 

FRIDAY, JANUARY 22, 2010

Session 4: Cancer Epigenomes

8:00 a.m.-10:00 a.m.


Title to be announced
Kornelia Polyak, Dana-Farber Cancer Institute, Boston, MA

Title to be announced
Andrew P. Feinberg, Johns Hopkins University School of Medicine, Baltimore, MD

Mechanisms of epigenetic plasticity in stem cells and tumor cells
Thea D. Tlsty, University of California San Francisco Medical School, San Francisco, CA

Session 5: Clinical Implications

11:00 a.m.-1:00 p.m.


Gene methylation for the early detection of cancer
Paul Cairns, Fox Chase Cancer Center, Philadelphia, PA

Epigenetics diagnose what genetics cannot
Toshikazu Ushijima, National Cancer Center Research Institute, Tsukiji, Japan

DNA methylation as a predictive and prognostic biomarker
James G. Herman, Johns Hopkins University School of Medicine, Baltimore, MD

Poster Session B

4:00 p.m.-7:00 p.m.

Session 6: Epigenetic Therapies

7:00 p.m.-9:00 p.m.


DNA methylation inhibitors for chemotherapy resensitization of solid tumors
Kenneth P. Nephew, Indiana University School of Medicine, Bloomington, IN

Combined therapy with agents targeted against deregulated epigenetic mechanisms in cancer
Kapil N. Bhalla, MCG Cancer Center, Medical College of Georgia, Augusta, GA

Title to be announced
Yi Zhang, UNC Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC

 

SATURDAY, JANUARY 23, 2010

Session 7: Establishing the Markers

8:00 a.m.-10:00 a.m.


Title to be announced
Stephen B. Baylin, Johns Hopkins University School of Medicine, Baltimore, MD

Title to be announced
Arul M. Chinnaiyan, University of Michigan, Ann Arbor, MI

Consolidation of epigenetic marks in cancer
Susan J. Clark, Garvan Institute of Medical Research, Sydney, Australia

Session 8: Environmental Effects on the Epigenome

11:00 a.m.-1:00 p.m.


Interindividual epigenetic variation
Robert Waterland, Baylor College of Medicine, Houston, TX

Title to be announced
Cornelia M. Ulrich, Fred Hutchinson Cancer Research Center, Seattle, WA

Title to be announced
Cheryl L. Walker, UT M. D. Anderson Cancer Center, Smithville, TX

Session 9: Workshop and Bioinformatics Poster Session

4:00 p.m.-5:00 p.m.


No more lame lanes: Inferring genomic organization from epigenomic experiments
Amos Tanay, The Weizmann Institute of Science, Rehovot, Israel

A genomic view of epigenetic and transcriptional regulation in cancer
Wei Li, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX

Title to be announced
Peter W. Laird, USC Epigenome Center, Los Angeles, CA

Session 10: Late Breaking News

5:00 p.m.-7:00 p.m.


Presentations from proffered abstracts and late-breaking papers

Departure