American Association for Cancer Research

Program

Pancreatic Cancer 2014

Program as of March 26; subject to change

Sunday, May 18

Opening Plenary Session

7:00 p.m.-8:30 p.m.

Dynamics and evolution of pancreatic cancer from inception to dissemination
Christine Iacobuzio-Donahue, Memorial Sloan Kettering Cancer Center, New York, NY

Title to be announced
Robb Lamont, Survivor-Advocate, Tampa Bay, FL

Opening Reception

8:30 p.m.-10:00 p.m.

 

Monday, May 19

Continental Breakfast/Meet-the-Expert Roundtables

7:00 a.m.-8:00 a.m.

Plenary Session 1: Development

8:00 a.m.-10:30 a.m.
Session Chairperson: Howard C. Crawford, Mayo Clinic Florida, Jacksonville, FL

Cellular origins of pancreatic ductal adenocarcinoma
Maike Sander, University of California, San Diego, CA

Title to be announced
Timothy C. Wang, Columbia University, New York, NY

Translating genetic discoveries to patient care
Ralph Hruban, Johns Hopkins University, Baltimore, MD

Signaling pathways in pancreatic tumorigenesis
Brian C. Lewis, University of Massachusetts Medical School, Worcester, MA

Break

10:30 a.m.-10:50 a.m.

Plenary Session 2: Inflammation/Stroma

10:50 a.m.-1:20 p.m.

Innate immune signaling in pancreatic TME
George Miller, New York University School of Medicine, New York, NY

Tumor-stroma dynamics in pancreatic cancer
Mikala Egeblad, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

Title to be announced
Ronald M. Evans, Salk Institute for Biological Sciences, La Jolla, CA

Targeting the microenvironment: Challenges and opportunities
George Fisher, Stanford Cancer Center, Stanford, CA

Lunch Break

1:20 p.m.-2:30 p.m.

Plenary Session 3: Impacts of Heterogeneity in Tumor Progression

2:30 p.m.-4:45 p.m.
Session Chairperson: Christine Iacobuzio-Donahue, Memorial Sloan Kettering Cancer Center, New York, NY

Generation of intratumoral heterogeneity via RNA-DNA differences in pancreatic cancer
Andrew Rhim, University of Michigan Medical School, Ann Arbor, MI

Stem cell signals in cancer growth and progression
Tannishtha Reya, University of California, San Diego, CA

Signaling networks linking pancreatitis to pancreatic tumorigenesis
Howard C. Crawford, Mayo Clinic Florida, Jacksonville, FL

Remarks
Kerri Kaplan, Lustgarten Foundation, Bethpage, NY

Remarks
Julie M. Fleshman, Pancreatic Cancer Action Network, Manhattan Beach, CA

Poster Session A

4:30 p.m.-7:00 p.m.

 

Tuesday, May 20

Continental Breakfast/Meet-the-Expert Roundtables

7:00 a.m.-8:00 a.m.

Plenary Session 4: Diagnostics

8:00 a.m.-10:00 a.m.
Session Chairperson: Andrew M. Lowy, University of California – San Diego, San Diego, CA

Title to be announced
Raghu Kalluri, The University of Texas MD Anderson Cancer Center, Houston, TX

Circulating tumor DNA
Luis A. Diaz, Johns Hopkins Kimmel Comprehensive Cancer Center, Baltimore, MD

New methods of PET imaging pancreas cancer
Jason Lewis, Memorial Sloan Kettering Cancer Center, New York, NY

Break

10:00 a.m.-10:30 a.m.

Plenary Session 5: Metabolism

10:30 a.m.-12:30 p.m.
Session Chairperson: Alec C. Kimmelman, Dana-Farber Cancer Institute, Boston, MA

Transcriptional regulation of pancreatic cancer metabolism
Nabeel Bardeesy, Massachusetts General Hospital Cancer Center, Boston, MA

Obesity, inflammation, and pancreatic cancer
Guido Eibl, UCLA David Geffen School of Medicine, Los Angeles, CA

p53 and autophagy in pancreatic cancer
Kevin Ryan, Cancer Research UK Beatson Institute, Glasgow, United Kingdom

Poster Session B / Lunch

12:30 p.m.-3:00 p.m.

Plenary Session 6: Immunology

3:00 p.m.-5:00 p.m.
Session Chairperson: Dafna Bar-Sagi, New York University School of Medicine, New York, NY

Harnessing the immune reaction associated with pancreas carcinoma for therapy
Greg Beatty, University of Pennsylvania, Philadelphia, PA

Stromal cell-dependent immune suppression in pancreatic cancer
Douglas Fearon, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom

Innate immune cell PI3K gamma as a target for suppression of pancreatic ductal carcinoma
Judy Varner, Moores Cancer Center, University of California, San Diego, CA

 

Wednesday, May 21

Continental Breakfast/Meet-the-Expert Roundtables

7:00 a.m.-8:00 a.m.

Plenary Session 7: New Therapies

8:00 a.m.-10:00 a.m.
Session Chairperson: Eileen O’Reilly, Memorial Sloan Kettering Cancer Center, New York, NY

Title to be announced
Gregory L. Verdine, Harvard University, Cambridge, MA

Kras and the inflammatory microenvironment in pancreatic cancer initiation and maintenance
Marina Pasca di Magliano, University of Michigan, Ann Arbor, MI

Targeting K-Ras signaling in pancreatic cancer
Mariano Barbacid, Spanish National Cancer Research Center (CNIO), Madrid, Spain

Break

10:00 a.m.-10:30 a.m.

Plenary Session 8: Clinical Science Trials

10:30 a.m.-12:30 p.m.
Session Chairperson: David A. Tuveson, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY

Title to be announced
Brian Wolpin, Dana-Farber Cancer Institute, Boston, MA

Title to be announced
Christopher Crane, The University of Texas MD Anderson Cancer Center, Houston, TX

BRCA-related pancreas adenocarcinoma: New directions in therapy
Eileen O’Reilly, Memorial Sloan-Kettering Cancer Center, New York, NY

Departure

1:00 p.m.