October 25 - 28, 2006
Hyatt Regency Cambridge
Ronald A. DePinho, Dana-Farber Cancer Institute, Boston, MA
Joanna L. Groden, The Ohio State University, Columbus, OH
Tyler E. Jacks, Massachusetts Institute of Technology, Cambridge, MA
Scott W. Lowe, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
Mouse models of cancer provide us with the ability to learn about tumor biology in complicated and dynamic physiological systems. Previous efforts to model cancer in the mouse have produced fundamental insights into various aspects of cancer, including the action of oncogenes and tumor suppressor genes, the biology of tumor-host cell interactions, the factors that influence cellular responsiveness to chemotherapeutic agents, and the relationship between genes that influence tumorigenesis and those that affect organismal aging.
The 2006 Mouse Models of Cancer conference was the fifth conference focusing on mouse models by the AACR. Over 450 scientists, researchers, and students from 20 different countries gathered outside of Boston to discuss cutting edge research that involved the use of mouse models as tools to investigate basic biological mechanisms of growth and differentiation, and as systems to test new approaches to diagnosing and treating cancer. Over 30 invited talks and nearly 150 proffered papers were presented on topics including tissue microenvironment, inflammatory biology, cancer stem cells, experimental therapeutics, genomic instability, and aging. New technologies were explored and presentations featured the latest research on RNA interference, whole animal imaging, and insertional mutagenesis. Tumor models representative of cancers of the intestine, breast, brain, skin and hematopoietic system, as well as metastasis were also discussed.
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Please visit the AACR Meeting Calendar for a complete list of upcoming programs.