American Association for Cancer Research

Poster Session B

Poster Session B
Sunday, February 7
6:30 p.m.-8:00 p.m.

In alphabetical order, not board assignment order

  • 6-(methylsulfinyl)hexyl isothiocyanate derived from wasabi (Wasabia japonica Matsum) regulates RhoB by inhibition of HDAC in B16BL6 mouse melanoma. Yoko Fuke, Atsushi Shimada. Graduate School of Human Health Sciences, Tokyo Metropolitan University, Tokyo, Japan.
  • A genome-wide association study for keloid disease in Japanese population. Nakashima Mitsuko1, Zembutsu Hitoshi1, Takahashi Atsushi2, Su-Youn Chung1, Kubo Michiaki2, Nakamura Yusuke1. 1Institute of Medical Science, University of Tokyo, Tokyo, Japan, 2Center for Genomic Medicine, RIKEN, Kanagawa, Japan.
  • A genome-wide association study of diffuse large B-cell lymphoma in Japanese. Vinod Kumar Magadi Gopalaiah1, Koichi Matsuda1, Michiaki Kubo2, Nakamura Yusuke1. 1Institute of Medical Science, University of Tokyo, Tokyo, Japan, 2Institute of Physical and Chemical Research, RIKEN, Kanagawa, Japan.
  • AKT1 polymorphisms and survival of early-stage non-small cell lung cancer. Min Jung Kim1, Hyo-Gyoung Kang1, Jin Eun Choi1, Yi Young Choi1, Hyo-Sung Jeon1, Shin Yup Lee2, Jae Yong Park2. 1Kyungpook National University School of Medicine, Daegu, Republic of Korea, 2 Kyungpook National University Hospital, Daegu, Republic of Korea.
  • Alternative lengthening of telomeres (ALT) correlates with nuclear pleomorphism, abnormal karyotypes, and anaphase bridges in soft tissue neoplasms. Hiroshi Iwasaki, Masako Ishiguro, Kazuki Nabeshima. Fukuoka University Faculty of Medicine, Fukuoka, Japan.
  • Association between the UGT1A1 polymorphism, bilirubin levels, and dyslipidemia in endometrial cancer. Satoko Matsumura, Akira Hirasawa, Tomoko Akahane, Kazuya Makita, Tomohiko Tsuruta, Kouji Banno, Nobuyuki Susumu, Daisuke Aoki. School of Medicine, Keio University, Tokyo, Japan.
  • BORIS regulates the cellular cycle of breast cancer cells through cyclin D1 expression. Tomomi Sato, Tetsu Hayashida, Tatsuya Oonishi, Koji Okabayashi, Hiromitsu Jinno, Tomonobu Fujita, Yutaka Kawakami, Yuko Kitagawa. Keio University, Tokyo, Japan.
  • Cadmium promotes breast cancer cell proliferation and gene expression. Maggie C. Louie, Christina L. Siewit, Esera Vegas. Dominican University, San Rafael, CA.
  • Cancer stem cells in glioblastoma multiforme: Identification of signaling pathways. Ladislau Albert1, Michael Karsy1, D. Ryan Ormond1, Alex Braun2, Raj Murali1, Meena Jhanwar-Uniyal1. Departments of 1Neurosurgery and 2Pathology, New York Medical College, Valhalla, NY.
  • Chemotaxis of fallopian tube cancer-initiating cells by ovulating follicle: Implication of fallopian tube origin of serous ovarian carcinoma. Yeh Ching-Hua, Lin Se-Ju, Liu Hwan-Wun, Chu Tang-Yuan. Buddhist Tzu Chi General Hospital, Tzuchi University, Hualien, Taiwan.
  • Comprehensive analysis of DNA repair gene polymorphisms and survival of early-stage non-small cell lung cancer. Deuk Kju Jung1, Hyo-Gyoung Kang2, Yi Young Choi2, Hyo-Sung Jeon1, Eung Bae Lee3, Sukki Cho3, Sanghoon Jheon4, Jae Yong Park5. Departments of 1Diagnosis and Prediction Biotechnology, 2Biochemistry and Molecular Biology, 3Thoracic Surgery, and 5Internal Medicine, Kyungpook National University School of Medicine, Daegu, Republic of Korea, 4Seoul National University School of Medicine, Seoul, Republic of Korea.
  • Critical role of transactivation of ERAP1, estrogen receptor activity-regulated protein 1, in estrogen-dependent breast cancer cells. Katagiri Toyomasa1, Nakamura Yusuke2. 1Institute for Genome Research, University of Tokushima, Tokushima, Japan, 2Institute of Medical Science, University of Tokyo, Tokyo, Japan.
  • Different impact of loss of heterozygosity at BRCA1 and BRCA2 loci on breast cancer prognosis by the subtype approximated by estrogen receptor, progesterone receptor, and HER2. Satoko Okada1, Eriko Tokunaga1, Nami Yamashita1, Natsumi Yamashita2, Keiji Yoshinaga1, Hiroshi Saeki1, Hiroyuki Kitao3, Yasunori Emi2, Masaru Morita1, Yoshihiro Kakeji1, Yoshihiko Maehara1. Departments of 1Surgery and Science, 2 Innovative Applied Oncology, and 3Molecular Oncology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Distinct somatic mutation patterns in multiple human cancers and their subtypes. Somasekar Seshagiri, Kan Zhengyan. Genentech, Inc., South San Francisco, CA.
  • Effect of radiation exposure on risk of hepatocellular carcinoma in atomic bomb survivors. Waka Ohishi1, Saeko Fujiwara1, John B. Cologne1, Masazumi Akahoshi1, Yasuharu Niwa1, Gen Suzuki2, Masataka Tsuge3, Kazuaki Chayama3. 1Radiation Effects Research Foundation, Hiroshima, Japan, 2International University of Health and Welfare Clinic, Ohtawara, Japan, 3Hiroshima University, Hiroshima, Japan.
  • Enforced expression of PRL-3 inhibits cell invasion and proliferation on NSCLC carcinoma. Sheng-Yi Lin1, Yueh-Hsun Lee1, Chi-Mei Hsueh1, Sung-Liang Yu2, Gee-Chen Chang3, Jeremy J.W. Chen1. 1National Chung Hsing University, Taichung, Taiwan, 2National Taiwan University College of Medicine, Taipei, Taiwan, 3Taichung Veterans General Hospital, Taichung, Taiwan.
  • EpCAM regulation is associated with the maintenance of pluripotency in human embryonic stem cells. Cheng-Fu Kao1, Tung-Ying Lu2, Ruei-Min Lu1, Mei-Ying Liao1, John Yu1, Han-Chung Wu1. 1Institute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, 2Institute of Pathology, National Taiwan University, Taipei, Taiwan.
  • Exploration of molecular markers for cancer stem cells and the possible application to tageting therapy. Toshihiko Torigoe1, Yoshihiko Hirohashi1, Akari Takahashi2, Satoshi Nishizawa1, Lena Morita1, Noriyuki Sato1. 1Sapporo Medical University, Sapporo, Hokkaido, Japan, 2JST Innovation Plaza Hokkaido, Sapporo, Hokkaido, Japan.
  • Factors associated with antidepressant use among breast cancer survivors and feasibility of conducting pharmacogenomics studies in a large health plan. Reina Haque, Chantal C. Avila, Jiaxiao M. Shi, Virginia P. Quinn. Kaiser Permanente Southern California, Pasadena, CA.
  • Functional analysis of BRCA1 variants using a mouse ES cell-based assay and humanized mouse models. Suhwan Chang, Kajal Biswas, Shyam K. Sharan. Mouse Cancer Genetics Program, National Cancer Institute, Frederick, MD.
  • Functional and immunohistochemical analyses of a novel protein upregulated in colorectal cancers. Satoshi Nagayama1, Ryo Takahashi1, Seiya Imoto2, Moritoshi Furu3, Toyomasa Katagiri4, Yusuke Nakamura2, Junya Toguchida3, Yoshiharu Sakai1. 1Kyoto University Hospital, Kyoto, Japan, 2Institute of Medical Science, University of Tokyo, Tokyo, Japan, 3Institute for Frontier Medical Science, Kyoto University, Kyoto, Japan, 4Institute of Genome Research, Tokushima University, Tokushima, Japan.
  • Genetic polymorphism involved in estrogen metabolism and endometrial cancer risk. Akira Hirasawa, Satoko Matsumura, Tomohiko Tsuruta, Kouji Banno, Nobuyuki Susumu, Daisuke Aoki. School of Medicine, Keio University, Tokyo, Japan.
  • Genome-wide association study (GWAS) of gallbladder cancer in Japanese population. Pei-Chieng Cha1, Hitoshi Zembutsu1, Atsushi Takahashi2, Naoyuki Kamatani2, Michiaki Kubo2, Yusuke Nakamura1. 1Institute of Medical Science, University of Tokyo, Tokyo, Japan, 2RIKEN Center for Genomic Medicine, Yokohama, Kanagawa, Japan.
  • Genome-wide association study identified colorectal cancer susceptible loci in Asians. Ri Cui1, Koichi Matsuda1, Michiaki Kubo2, Yusuke Nakamura1. 1Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan, 2Center for Genomic Medicine, The Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.
  • Genome-wide association study identifies five new susceptibility loci for prostate cancer in Japanese population. Ryo Takata1, Shusuke Akamatsu1, Michiaki Kubo2, Naoya Hosono2, Atsushi Takahashi2, Takahisa Kawaguchi2, Tatsuhiko Tsunoda2, Naoyuki Kamatani2, Osamu Ogawa3, Tomoaki Fujioka4, Yusuke Nakamura5, Hidewaki Nakagawa1. 1Center of Genome Medicine, RIKEN, Tokyo, Japan, 2Center of Genome Medicine, RIKEN, Yokohama, Japan, 3Graduate School of Medicine, Kyoto University, Kyoto, Japan, 4Iwate Medical University, Morioka, Japan, 5Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan.
  • Genome-wide association study of pancreatic cancer in Japanese population. Siew-Kee Low1, Aya Kuchiba2, Hitoshi Zembutsu1, Akira Saito2, Atsushi Takahashi3, Michiaki Kubo3, Yataro Daigo1, Naoyuki Kamatani3, Teruhiko Yoshida2, Yusuke Nakamura1, Hiromi Sakamoto2. 1Institute of Medical Science, University of Tokyo, Tokyo, Japan, 2National Cancer Center Research Institute, Tokyo, Japan, 3Center of Genomic Medicine, RIKEN, Kanagawa, Japan.
  • Genome-wide screen with CGH and gene expression array to identify novel factors involved in neuroblastoma tumorigenesis in a murine model. Satoshi Kishida1, Peng Huang1, Hitoshi Ichikawa2, Kenji Kadomatsu1. 1Nagoya University Graduate School of Medicine, Nagoya, Japan, 2National Cancer Center, Tokyo, Japan.
  • Genomic studies on prostate cancer disparities reveals gene network targets for therapeutic intervention. Bi-Dar Wang1, Ramez Andrawis2, Fernando J. Bianco2, Thomas Jarrett2, Harold Frazier2, James Tall1, Norman H. Lee1, Steven R. Patierno1. 1The George Washington University Cancer Institute, Washington, DC, 2The George Washington University Medical Faculty Associates, Washington, DC.
  • Germline copy number variants associated with breast cancer risk also harbor miRNA sequences: Comparison of miRNAs from breast cancer cases and controls in a population setting. Badan S. Sehrawat, Carol E. Cass, Russell Greiner, Jack Tuszynski, Raymond Lai, John R. Mackey, Sambasivarao Damaraju. University of Alberta and Cross Cancer Institute, Alberta Health Services, Edmonton, Canada.
  • hCLCA2, a p53 inducible transmembrane protein, regulates cancer cell migration and adhesion. Yasushi Sasaki, Ikuko Yokota, Lisa Kashima, Masashi Idagawa, Hiromu Suzuki, Minoru Toyota, Kohzoh Imai, Yasuhisa Shinomura, Takashi Tokino. Sapporo Medical University School of Medicine, Sapporo, Japan.
  • Homozygous deletion of CDKN2A/2B is a hallmark of iron-induced high-grade rat mesothelioma. Qian Hu1, Takahashi Takashi2, Toyokuni Shinya2. 1Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2Nagoya University Graduate School of Medicine, Nagoya, Japan.
  • Identification and characterization of a novel therapeutic target with glycosylation activity in mammary carcinogenesis. Jae-Hyun Park1, Chikako Fukukawa2, Yusuke Nakamura2, Toyomasa Katagiri3. 1Center for Genomic Medicine, RIKEN, Tokyo, Japan, 2Human Genome Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan, 3Institute for Genome Research, University of Tokushima, Tokushima, Japan.
  • Identification and characterization of early growth response gene-2 as a p53-regulated proapoptotic gene. Ikuko Yokota, Yasushi Sasaki, Naoki Anbo, Lisa Kashima, Masashi Idogawa, Takashi Tokino. Sapporo Medical University, Sapporo, Hokkaido, Japan.
  • Identification of association of genetic variations in HLA-DP locus with chronic hepatitis B in Asian population through genome-wide association study. Koichi Matsuda1, Yoichiro Kamatani1, Michiaki Kubo2, Yusuke Nakamura1. 1Institute of Medical Science, University of Tokyo, Tokyo, Japan, 2RIKEN, Yokohama, Japan.
  • Identification of germline copy number variants and their potential role in conferring breast cancer risk. Badan Sehrawat1, Russell Greiner2, Raymond Lai3, Jack Tuszynski4, Carol Cass4, John Mackey4, Sambasivarao Damaraju3. 1University of Alberta/Cross Cancer Institute, Edmonton, Alberta, Canada, Departments of 2Computing Science, 3Laboratory Medicine and Pathology, and 4Oncology, 1University of Alberta, Edmonton, Alberta, Canada.
  • Identification of lung cancer stem/initiating cells from non-small-cell lung cancer patients. Wan-Jiun Chen1, Huei-Wen Chen2, Chao-Chi Ho3, Hsuan-Yu Chen4, Pan-Chyr Yang3. 1Graduate Institute of Oncology, National Taiwan University Medical College, Taipei, Taiwan, 2Graduate Institute of Toxicology, National Taiwan University Medical College, Taipei, Taiwan, 3National Taiwan University Hospital and National Taiwan University, Taipei, Taiwan, 4Institute of Statistical Science, Academia Sinica, Taipei, Taiwan.
  • Individuals susceptible to lung adenocarcinoma defined by combined HLA-DQA1 and TERT genotypes. Takashi Kohno1, Hideo Kunitoh2, Jun Yokota1.
  • Initiation of malignancy by duodenal contents reflux and the role of ezrin in developing esophageal squamous cell carcinoma. Ken-ichi Mukaisho, Hiroyuki Sugihara, Takanori Hattori. Shiga University of Medical Science, Otsu, Shiga, Japan.
  • Integration of TCF4 with TGF-β/Smad pathway plays a key role in regulation of TMEPAI gene. Naoko Nakano, Yukihide Watanabe, Fumiko Itoh, Susumu Itoh, Mitsuyasu Kato. University of Tsukuba, Tsukuba, Japan.
  • Integrative genomic studies pertaining to cigarette smoke and human lung carcinogenesis. Maocheng Yang, Sichuan Xi, Fang Liu, Mahadev Rao, Mary Zhang, David S. Schrump. Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD.
  • Interaction between endometrial mesenchymal stem cells and cancer cells. Ding Dah-Ching, Chu Tang-Yuan. Buddhist Tzu Chi General Hospital, Tzu Chi University, Hualien, Taiwan.
  • Isoflavone intake and risk of lung cancer: A prospective cohort study in Japan. Taichi Shimazu, Manami Inoue, Shizuka Sasazuki, Motoki Iwasaki, Norie Sawada, Taiki Yamaji, Shoichiro Tsugane. Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan.
  • Isolation and characterization of a population of stem-like progenitor cells from an atypical meningioma. Prakash Rath1, Douglas C. Miller2, N Scott Litofsky2, Douglas C. Anthony2, Qi Feng2, Franklin Craig2, Lirong Pei1, Alan Free1, Mark D. Kirk2, Huidong Shi1. 1Medical College of Georgia, Augusta, GA, 2University of Missouri, Columbia, MO.
  • MEK1 dependent leukemogenic activity of Trib1. Takashi Yokoyama, Takuro Nakamura. Japanese Foundation for Cancer Research, Tokyo, Japan.
  • MUTYH, a molecular switch for programmed cell death and tumor suppression. Sugako Oka, Yusaku Nakabeppu. Division of Neurofunctional Genomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
  • Oligonucleotide-based array-CGH reveals recurrent genomic aberrations in malignant mesothelioma cell lines. Hideki Murakami, Tetsuya Mizuno, Makiko Fujii, Yutaka Kondo, Hirotaka Osada, Yoshitaka Sekido. Aichi Cancer Center Research Institute, Nagoya, Japan.
  • Regulation of neural stem cell proliferation in Drosophila. Norma Takaesu, Michael Stinchfield, Stuart Newfeld. Arizona State University, Tempe, AZ.
  • Roles of molecules complexes consisting of Cyr61, integrins, and Rho-GAP in the metastasis of mouse lung cancers. Qing Zhang1, Keiko Furukawa2, Yasuyuki Matsumoto1, Koichi Furukawa1. 1Nagoya University Graduate School of Medicine, Nagoya City, Aichi Prefecture, Japan, 2Chubu University College of Life and Health Sciences, Kasugai City, Aichi Prefecture, Japan.
  • SMCP is a novel cancer stem cell gene associated with in vivo tumor initiation capacity. Akari Takahashi1, Toshihiko Torigoe2, Yoshihiko Hirohashi2, Yasuaki Tamura2, Hiroko Asanuma2, Satoko Inoda2, Noriyuki Sato2. 1Innovation Plaza Hokkaido, JST, Sapporo-Shi, Hokkaido, Japan, 2Sapporo Medical University School of Medicine, Sapporo-Shi, Hokkaido, Japan.
  • Targeted delivery of NRASQ61R and Cre-recombinase to melanocytes induces melanoma in Ink4a/Arf lox/lox mice. Matthew W. VanBrocklin, James P. Robinson, Kristin J. Lastwika, Sheri L. Holmen. Nevada Cancer Institute, Las Vegas, NV.
  • TGF-β suppresses heme oxygenase-1 expression through inhibition of Nrf2 transcriptional activity. Yukari Okita1, Hiroyuki Suzuki1, Ken Itoh2, Hozumi Motohashi3, Kazuhiko Igarashi3, Masayuki Yamamoto3, Mitsuyasu Kato1. 1University of Tsukuba, Tsukuba, Japan, 2Hirosaki University, Hirosaki, Japan, 3Tohoku University, Sendai, Japan.
  • The involvement of HMGA2 in mesenchymal oncogenesis. Jørn Henriksen1, Marianne Stabell1, Leonardo A. Meza-Zepeda1, Eva W. Pedersen1, Moustapha Kassem2, Ola Myklebost1. 1Institute for Cancer Research, Oslo, Norway, 2University Hospital of Odense and Medical Biotechnology Center, Odense, Denmark.
  • The proliferation and survival of retinoblastoma tumor cells is dependent on cone-specific TRβ2-p107-Skp2 signaling pathway. Xiaoliang Leon Xu, David H. Abramson, David Cobrinik, Suresh C. Jhanwar. Memorial Sloan-Kettering Cancer Center, New York, NY.
  • The role of YB-1, a binding partner of nucleophosmin, in hematopoiesis and nucleophosmin mutant (NPMc)-associated acute myeloid leukemia. Yoko Ogawara1, Takuo Katsumoto1, Takeshi Uchiumi2, Kimitoshi Kohno3, Issay Kitabayashi1.
  • The WRN-encoded RecQ helicase acts as a tumor suppressor in pancreatic adenocarcinoma. Stephen G. Chun1, Nelson S. Yee2, Fang Qi1, Richard Allsopp1, Davy M. Philip1, Keith S. Fong1, Michele Carbone1, Peter K. Bryant-Greenwood1. 1University of Hawaii, Honolulu, HI, 2University of Iowa, Iowa City, IA.
  • Tsc-22 inhibits cellular proliferation through regulation of c-Myc and Oct4. Hiroyuki Suzuki1, Yuka Nakajo1, Akinobu Nakano2, Yuko Nakayama1, Mitsuyasu Kato1. 1University of Tsukuba, Tsukuba, Japan, 2Shimane University, Shimane, Japan.
  • Weight gain during adulthood and body weight at age 20 are associated with the risk for endometrial cancer in Japanese women. Satoyo Hosono1, Keitaro Matsuo1, Hidemi Ito1, Kaoru Hirose2, Takeshi Suzuki3, Kawase Takakazu1, Miki Watanabe1, Toru Nakanishi4, Kazuo Tajima5, Hideo Tanaka1. 1Division of Epidemiology and Prevention, Aichi Cancer Center Research Institute., Nagoya, Japan, 2Aichi Prefectural Institute of Public Health, Nagoya, Japan, 3Nagoya City University, Nagoya, Japan, 4Aichi Cancer Center Hospital, Nagoya, Japan, 5Aichi Cancer Center Research Institute, Nagoya, Japan.
Poster Session A Poster Session B Poster Session C Poster Session D