February 1-4, 2010
Omni San Diego Hotel
San Diego, California
Wafik S. El-Deiry, University of Pennsylvania, Philadelphia, PA
John C. Reed, Burnham Institute for Medical Research, La Jolla, CA
Eileen P. White, The Cancer Institute of New Jersey and Rutgers University, New Brunswick, NJ
Cell death suppression is extremely relevant for tumor development, progression, and resistance to therapy. The mechanisms of cell death and cell survival are complex and involve much more than previously thought (apoptosis and necrosis) with cross-talk and other programmed processes such as autophagy, post-mitotic death, or entosis. In addition, the tumor microenvironment has a great impact on cell death, cell signaling, tumor metabolism, cell survival, and therapeutic response. It is important to learn about how these aspects are inter-related and how different cell types including stem cells undergo cell death in response to external microenvironment stimuli or targeted therapeutics. The central focus of the conference was cell death regulation and how to mine and exploit it for therapeutic gain. Thie conference included new complexities of cell death and cell survival, new technologies, and clinical translational aspects necessary for the evolution of new therapeutic strategies.
* Adobe Acrobat Reader required
Please visit the AACR Meetings & Workshops Calendar for a complete list of upcoming programs.