Poster Session B
Tuesday, June 8
1:00 p.m.-4:00 p.m.
In alphabetical order, not board assignment order
- An interaction between SNPs in CAT and CYP1A1 significantly modifies the risk of bladder cancer among smokers. Andre F. S. Amaral1, Nathaniel Rothman2, Manolis Kogevinas3, Montserrat García-Closas2, Debra T. Silverman2, Kenneth P. Cantor4, Cristiane Murta-Nascimento3, Gemma Vellalta3, Adonina Tardón5, Alfredo Carrato6, Consol Serra7, Reina García-Closas8, Stephen Chanock2, Francisco X. Real1, Nuria Malats1. 1Spanish National Cancer Research Centre (CNIO), Madrid, Spain, 2National Cancer Institute, Bethesda, MD, 3Municipal Institute of Medical Research (IMIM), Barcelona, Spain, 4KP Cantor Environmental LLC, Silver Spring, MD, 5University of Oviedo, Oviedo, Spain, 6University Hospital of Elche, Elche, Spain, 7University Pompeu Fabra, Barcelona, Spain, 8University Hospital of the Canary Islands, La Laguna, Spain.
- Association of thymidylate synthase gene polymorphisms and markers of one-carbon metabolism. Vikki Ho, Thomas E. Massey, Will D. King. Queen's University, Kingston, ON, Canada.
- Biomarker panel discovery for early detection of colorectal cancer in blood samples. Leanne Purins1, Bruce Tabor2, Ilka Priebe1, Trevor Lockett3, Ed Nice4, Tony Burgess4, Peter Gibbs4, Leah Cosgrove1. 1CSIRO FNS and PHealth, Adelaide, Australia, 2CSIRO CMIS and PHealth, Sydney, Australia, 3CSIRO FNS and PHealth, Sydney, Australia, 4LICR, Melbourne, Victoria, Australia.
- Changes in DNA methylation patterns in workers of a Thai industrial estate and nearby residents. Marco Peluso1, Valentina Bollati2, Petcharin Srivatanakul3, Armelle Munnia1, Ceppi Marcello4, Piro Sara1, Boffetta Paolo5. 1ISPO-Cancer Prevention and Research Institute, Florence, Italy, 2University of Milan and IRCCS Maggiore Hospital, Milan, Italy, 3NCI, Bangkok, Thailand, 4NCI, Genoa, Italy, 5IARC, Lyon, France.
- Continued identification of ethnic specific differences in breast tissue: On the road to biomarker discovery in breast cancer. Lisa L. Baumbach-Reardon, Mary Ellen Ahearn, Carmen Gomez, Aldo Mejias, Merce Jorda, Tom Halsey, Jim Yan, Kevin Ellison, Karl Mulligan, Mark Pegram. University of Miami Medical School, Miami, FL, Almac Diagnostics, Durham, NC.
- DNA methylation array analysis identifies profiles of blood-derived DNA methylation associated with bladder cancer. Carmen J. Marsit1, E. Andres Houseman1, Brock C. Christensen1, Devin Koestler1, Margaret Karagas2, Karl T. Kelsey1. 1Brown University, Providence, RI, 2Dartmouth Medical School, Lebanon, NH.
- Elevated serum levels of CXCL13 precede the diagnosis of B cell non-Hodgkin lymphoma (NHL). Lynn I. Levin1, Elizabeth Crabb Breen2, Christina R. Kitchen2, Daniel Widney2, Bong K. Kim3, Aizen J. Marrogi1, Rebekah L. Krampf1, Larry Magpantay2, Otoniel Martinez-Maza2. 1Walter Reed Army Institute of Research, Silver Spring, MD, 2University of California, Los Angeles, CA, 3Armed Forces Institute of Pathology, Washington, DC.
- EnviroGenomarkers: A European molecular epidemiology project on genomics biomarkers of environmental health. Soterios A. Kyrtopoulos1, Jos Kleinjans2, Paolo Vineis3, Ingvar A. Bergdahl4, Domenico Palli5, Euripides G. Stephanou6, Roel Vermeulen7, Pietro Comba8, Hannu Kiviranta9, Mark S. Gilthorpe10, Bo A. Jonsson11. 1National Hellenic Research Foundation, Athens, Greece, 2Maastricht University, Maastricht, The Netherlands, 3Imperial College, London, England, 4Umeå University, Umeå, Sweden, 5Istituto per lo Studio e la Prevenzione Oncologica, Florence, Italy, 6University of Crete, Heraklion, Greece, 7University of Utrecht, Utrecht, The Netherlands, 8Istituto Superiore di Sanita, Rome, Italy, 9National Institute for Health and Welfare, Kuopio, Finland, 10University of Leeds, Leeds, England, 11Lund University, Lund, Sweden.
- Estrogen receptor β expression in ovarian epithelial cancers. Shelley S. Tworoger1, Joanne Kotsopoulos1, Jonathan L. Hecht2. 1Brigham and Women's Hospital, Boston, MA, 2Beth Israel Deaconess Medical Center, Boston, MA.
- European hot spot of air pollution by PM2.5 and B[a]P: Ostrava, Czech Republic. Radim J. Sram, Alena Milcova, Pavel Rossner, Jr., Andrea Rossnerova, Jana Schmuczerova, Vlasta Svecova, Jan Topinka. Institute of Experimental Medicine AS CR, Prague, Czech Republic.
- Gene expression profiling of a population exposed to a range of benzene levels provides mechanistic and disease insights and a potential signature of exposure. Cliona M. Mchale1, Luoping Zhang1, Qing Lan2, Roel Vermeulen3 Guilan Li4, Alan E. Hubbard1, Kristin Porter1, Reuben Thomas5, Christopher J. Portier5, Min Shen2, Stephen M. Rappaport1, Songnian Yin4, Martyn T. Smith1, And Nathaniel Rothman2. 1School of Public Health, University of California, Berkeley, CA, 2Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD, 3Institute of Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands, 4Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China, 5Environmental Systems Biology Group, Laboratory of Molecular Toxicology, National Institute of Environmental Health Sciences, NC.
- Genetic polymorphisms in microRNA biogenesis pathway genes and breast cancer risk in Korean women. Hyuna Sung1, Kyoung-Mu Lee2, Ji-Yeob Choi3, Ji-Young Lee2, Lian Lee4, Sue K. Park2, Keun-Young Yoo2, Dong-Young Noh5, Sei-Hyun Ahn6, Daehee Kang1. 1Graduate School of Seoul National University, Seoul, Republic of Korea, 2Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea, 3Pharmacogenomics Research Center, Inje University College of Medicine, Busan, Republic of Korea, 4Department of Cancer Biology, Seoul National University College of Medicine, Seoul, Republic of Korea, 5Department of Surgery, Seoul National University College of Medicine, Seoul, Republic of Korea, 6University of Ulsan College of Medicine and Asan Medical Center, Seoul, Republic of Korea.
- Human serum albumin adducts of benzoquinone, naphthoquinone and phenanthrenequinone as biomarkers of exposure. Hasmik Grigoryan1, Suramya Waidyanatha2, He Li1, Marine Grigoryan1, Samantha Lu1, Stephen Rappaport1. 1School of Public Health, University of California, Berkeley, CA, 2Current address-National Institute of Environmental Health Sciences, Research Triangle Park, NC.
- Integrative modeling of genetic and epigenetic variation in colorectal cancer. Aditi Hazra1, Shuji Ogino2, David Hunter1. 1Harvard School of Public Health, Boston, MA, 2Dana Farber Cancer Institute, Boston, MA.
- Is there a relationship between mRNA expression levels of cancer progression related genes with prognosis in colorectal cancer patients? Miriam E. Uhlmann1, Martin Sill1, Ulrich Linnemann2, Martin R. Berger1. 1German Cancer Research Ctr., Heidelberg, Germany; 2Municipal Hospital, Clinic for Surgery, Nuernberg, Germany.
- Long-term immunologic effects among workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Fatemeh Saberi Hosnijeh, Daisy Boers, Lutzen Portengen, Dick Heederik, Roel Vermeulen. Institute of Risk Assessment Sciences, Utrecht University, Utrecht, Netherlands, Netherlands Antilles.
- Measuring polycyclic aromatic hydrocarbons in urine from Xuanwei, China as biomarkers of exposure to fuel smoke. Sixin Samantha Lu1, Qing Lan2, Boris Reiss3, Min Shen2, W. Hu4, J. Xu4, Nathaniel Rothman2, Roel Vermeulen3, Stephen M. Rappaport1. 1University of California, Berkeley, CA, 2National Cancer Institute, Bethesda, MD, 3Utrecht University, Utrecht, The Netherlands, 4China National Environmental Monitoring Center, Beijing, China.
- Metabolic and inflammatory markers as risk factors for pancreatic cancer: A prospective case-control study. Verena A. Grote1, Rudolf Kaaks1, Bas Bueno-de-Mesquita2, Sabine Rohrmann*1.1German Cancer Research Center (DKFZ), Division of Cancer Epidemiology, Heidelberg, Germany, 2National Institute for Public Health and the Environment (RIVM), Cancer Epidemiology, Bilthoven, The Netherlands. *on behalf of the EPIC group.
- Mining SNP genotype data reveals sites polymorphic within both the ALOX15 gene and pseudogene. K. W. Makar1, E. M. Poole1, L. Xiao1, M. L. Slattery2, D. Duggan3, L. Hsu1, K. Curtin2, J. Muehling3, D. Taverna3, B. J. Caan5, U. Peters1, C. S. Carlson1, J. D. Potter1, C. M. Ulrich1. 1Fred Hutchinson Cancer Research Center, Seattle, WA, 2University of Utah, School of Medicine, Salt Lake City, UT, 3Translational Genomics, Phoenix, AZ, 4UT Health Science Center, Houston, TX, 5Kaiser Permanente Medical Research Program, Oakland CA.
- Nationwide human biomonitoring of exposure to hazardous materials from foods consumption. Kyoung-Ho Lee1, Ryoung-Me Ahn2, Jin-Heon Lee3. 1Integrated Omics Center, Life and Health Division, Korea Institute of Science and Technology, Seoul, Korea (Rep.), 2Department of Health Science, Dongduk Women’s University, Seoul, Korea (Rep.), 3Department of Environmental Education, Kongju National University, Gongju, Korea (Rep.).
- Phospholipase A2A polymorphisms and risk of colorectal neoplasia. C. Abbenhardt1, E. M. Poole2, L. Xiao2, M. L. Slattery3,R. L. Galbraith2, D. Duggan4, L. Hsu2, K. W. Makar2, R. J. Kulmacz5, K. Curtin3, J. D. Potter2, B. J. Caan6, L. Koepl2, A. E. Coghill2, J. Muehling4, D. Taverna4, C. S. Carlson2, C. M. Ulrich1. 1German Cancer Research Center, Heidelberg, Germany, 2Fred Hutchinson Cancer Research Center, Seattle, WA, 3University of Utah, School of Medicine, Salt Lake City, UT, 4Translational Genomics Research Institute, Phoenix, AZ, 5UT Health Science Center at Houston, Houston, TX, 6Kaiser Permanente Medical Research Program, Oakland CA.
- Plasma concentrations of IGF-I and IGFBP3 and brain cancer risk in EPIC. Sabine Rohrmann1, Jakob Linseisen2, Susem Becker3, Rudolf Kaaks3. 1University of Zurich, Zurich, Switzerland, 2Helmholtz Center Munich, Munich, Germany, 3German Cancer Research Center, Heidelberg, Germany.
- Polymorphisms in DNA repair genes and non-familiar thyroid cancer risk. Bruno C. Gomes1, Rita Gouveia1, Susana N. Silva1, Hélder N. Bastos1, Sandra C. Branco1, Mónica Antão1, Ana P. Azevedo2, Octávia M. Gil3, Isabel Manita4, Luís S. Santos1, Teresa C. Ferreira5, Edward Limbert5, Jorge F. Gaspar1. 1Dept. of Genetics, Lisbon, Portugal, 2Dept. of Clinical Pathology, Hosp. S. Francisco Xavier, Lisbon, Portugal, 3Radiological Protection and Safety Unit ,Instituto Tecnológico e Nuclear,, Sacavém., Portugal, 4Unit. Endocrinology, Garcia de Orta Hospital,, Almada, Portugal, 5Dept. Nuclear Medicine, Portuguese Oncology Institute of Lisbon, Lisbon, Portugal.
- Prognostic effects of 25-hydroxyvitamin D serum concentrations in postmenopausal breast cancer. Alina Vrieling1, Dieter Flesch-Janys2, Jenny Chang-Claude1. 1German Cancer Research Center, Heidelberg, Germany, 2Institute for Medical Biometrics and Epidemiology, Hamburg, Germany.
- Proteomic identification of candidate biomarkers after exposure to the carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyrine and the immunotoxin deoxynivalenol. André Nogueira da Costa1, Renée Mijal1, Sarah Hepworth2, Jeffrey Keen3, Solvor Stolevik4, Unni Nygaard4, Ellen Namork4, Berit Granum4, Martinus Lovik4, Christopher P. Wild5, John B.C. Findlay3, Patricia McKinney2, Laura J. Hardie1. 1Molecular Epidemiology Unit, LIGHT Laboratories, University of Leeds, Leeds, England, 2Paediatric Epidemiology Group, LIGHT Laboratories, University of Leeds, Leeds, England, 3Research Institute of Membrane and Systems Biology, LIGHT Laboratories, University of Leeds, Leeds, England, 4Norwegian Institute of Public Health, Oslo, Norway, 5IARC, Lyon, France.
- Relationship between frozen tissue bank and cancer registries in France: Which contributions for molecular epidemiology? Cyrille Delpierre1, Magali Peter2, Pierre Brousset3, Marie-Bernadette Delisle3, Philippe Rochaix4, Pascale Grosclaude4. 1National Institute of Health and Medical Research, Toulouse, Haute Garonne, France, 2Oncomip, Toulouse, Haute Garonne, France, 3University Teaching Hospital, Toulouse, Haute-Garonne, France, 4Claudius Regaud Cancer Institute, Toulouse, Haute-Garonne, France.
- SET protein regulates expression of glutathione S-transferase pi 1 (GSTP-1) in oral carcinoma. Luciana Oliveira Almeida, Carlos Curti, Andréia Machado Leopoldino. São Paulo University, Ribeirão Preto, São Paulo, Brazil.
- Synergistic effect of HPV exposure and MDM2 variants on risk of oral squamous cell carcinoma. Yang Zhang, Erich M. Sturgis, Xingming Chen, Kristina Dahlstrom, Qingyi Wei, Guojun Li. UT M. D. Anderson Cancer Center, Houston, TX.
- The breast-cancer associated SNP rs11249433 and mRNA expression of the NOTCH2 gene. Yi-Ping Fu1, Hege Edvardsen2, Alpana Kaushiva1, Juan Arhancet1, Tiffany M. Howe1, Indu Kohaar1, Patricia Porter-Gill1, Anushi Shah1, Hege Landmark-Høyvik2, Sophie D. Fosså3, Stefan Ambs1, Bjørn Naume4, Anne-Lise Børresen-Dale2, Vessela N. Kristensen2, Ludmila Prokunina-Olsson1. 1National Cancer Institute, National Institutes of Health, Bethesda, MD, 2Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway, 3The Norwegian Radium Hospital, University of Oslo, Oslo, Norway, 4Cancer Clinic, Oslo University Hospital Radiumhospitalet, Oslo, Norway.
- The gut microbial community as biomarker of dietary exposure and cancer risk. Meredith A. J. Hullar. Fred Hutchinson Cancer Research Center, Seattle, WA.
- The role of global DNA methylation in breast cancer progression. Ji-Yeob Choi1, Soo Kyung Bae1, Kyung-Ah Seo1, Hyung Seok Park2, Chang-Woo Yeo1, Adam Karpf3, Byeong-Woo Park2, Jae-Gook Shin1. 1Pharmacogenomic Research Center, Inje University, Busan, Korea (Rep.), 2Yonsei University, Seoul, Korea (Rep.), 3Roswell Park Cancer Institute, Buffalo, NY.
- Third follow-up of a Dutch cohort occupationally exposed to chlorophenoxy herbicides, chlorophenols and dioxins. Daisy Boers1, Lutzen Portengen1, Bas Bueno-de-Mesquita2, Dick Heederik1, Roel Vermeulen1. 1Utrecht University, Utrecht, Netherlands; 2National Institute for Public Health and Environmental Protection, Bilthoven, Netherlands.
- Urinary excretion of phytoestrogens among middle-aged and elderly Chinese women. Xiaoyan Wu1, Hui Cai1, Yu-Tang Gao2, Qi Dai1, Honglan Li2, Qiuyin Cai1, Gong Yang1, Adrian A Franke3, Wei Zheng1, Xiao-Ou Shu1. 1 Vanderbilt University Medical Center, Nashville, TN, 2Shanghai Cancer Institute, Shanghai, China, 3Cancer Research Center of Hawaii, Honolulu, HI.
- Using sibling pairs to study the epigenetic effects of prenatal PAH exposure. Julie B. Herbstman, Deliang Tang, Frederica P. Perera. Columbia Center for Children's Environmental Health, Columbia University Mailman School of Public Health, New York, NY.