Poster Session A

Poster Session A
Monday, January 31
5:00 p.m.-7:00 p.m.

In alphabetical order, not board assignment order

• A novel mPGES-1 inhibitor with antitumor activity. Hui-Hua Chang, Zuohe Song, Tina Tripp, Lee Wisner, Vijay Gokhale, Chris Hulme, Emmanuelle J. Meuillet. University of Arizona, Tucson, AZ.
• An orange Monascus pigment induced apoptosis on human gastric adenocarcinoma AGS cells. Yunquan Zheng, Xian-Ai Shi, Yanghao Guo. Fuzhou University, Fuzhou, China.
• Caged nitric oxide prodrugs for cancer therapy. Anna E. Maciag¹, Joseph E. Saavedra¹, Ryan J. Holland², Lucy M. Anderson², Larry K. Keefer². ¹ SAIC-Frederick, Frederick, MD,² NCI-Frederick, Frederick, MD.
• Discovery of SHP-1 enhancer as apoptotic agents through inactivating STAT3. Kuen-Feng Chen¹, Jung-Chen Su², Jui-Wen Huang³, Wei-Lin Chen², Chun-Yu Liu⁴, Ann-Lii Cheng¹, Pei-Jer Chen¹, Chung-Wai Shiau². ¹ National Taiwan University Hospital, Taipei, Taiwan, ²National Yang-Ming University, Taipei, Taiwan, ³Industrial Technology Research Institute, Hsinchu, Taiwan, ⁴Taipei Veterans General Hospital, Taipei, Taiwan.
• DNA sequence context alters the oxidation chemistry and reactivity of 8-oxoguanine. Kok Seong Lim¹, Liang Cui¹, Koli Taghizadeh¹, John S. Wishnok¹, Vladimir Shafirovich², Nicholas E. Geacintov², Steven R. Tannenbaum¹, Peter C. Dedon¹. ¹ Massachusetts Institute of Technology, Cambridge, MA, ²New York University, New York, NY.
• Effects of a Mediterranean diet intervention on eicosanoid levels in colon biopsies. Zora Djuric, Jianwei Ren, D. Kim Turgeon, Mack R. Ruffin, IV, Maria Cornellier, Mary Rapai, Ananda Sen, Dean E. Brenner. University of Michigan, Ann Arbor, MI.
• Follicle stimulating hormone receptor and nerve growth factor in postmenopausal epithelial ovarian cancer. Chinmay K. Basu, Asis Mukhopadhyay. Netaji Cancer Research Institute, Kolkata, West Bengal, India.
• Fragment-based design of novel small-molecule inhibitors to selectively disrupt the β-catenin/Tcf protein-protein interactions. Haitao (Mark) Ji. University of Utah, Salt Lake City, UT.
• Fusarochromanone and novel analogs as anticancer agents. Elahe Mahdavian¹, Dakota Boston¹, Reid Grimes¹, Tara Williams-Hart¹, Brian Furmanski², John Clifford³, Brian Salvatore¹. ¹ Louisiana State University, Shreveport, LA, ²St. Jude Children's Research Hospital, Memphis, TN, ²LSUHSC, Shreveport, LA.
• In vitro and in vivo anticancer activity of a novel synthetic TLR4 activator. Yong-Shiang Lin¹, Chao-Hsiung Lin², Chun-Cheng Lin³, Shu-ling Fu⁴. ¹ Institute of Public Health, National Yang-Ming University, Taipei, Taiwan, ²Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan, ³Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan, ⁴Institute of Traditional Medicine, National Yang-Ming University, Taipei, Taiwan.
• In vivo imaging of cancer therapy with glucocorticoid-loaded nanoparticles in an experimental model. Anita Gianella¹, Peter A. Jarzyna¹, Willem J.M. Mulder¹, Venkatesh Mani¹, Sarayu Ramachandran¹, Claudia Calcagno¹, Jun Tang¹, Gert Storm², Victor L. Thijssen³, Arjan W. Griffioen³, Zahi A. Fayad¹. ¹ Mount Sinai School of Medicine, New York, NY, ²Utrecht Institute for Pharmacological Science, Utrech, The Netherlands, ³VUMC-Cancer Center, Amsterdam, The Netherlands.
• Inflammation in TGFβ-mediated carcinogenesis. B.R. Achyut, David A. Bader, Hannah H. Yan, Yanli Pang, Zhaoyang Li, Li Yang. National Cancer Institute, Bethesda, MD.
• Inflammation-mediated nitrosative deamination: RNA is more reactive than DNA and guanosine is more reactive than adenosine. Vasileios Dendroulakis, William M. Deen, Peter C. Dedon. Massachusetts Institute of Technology, Cambridge, MA.
• N6-formylation of lysine: A secondary modification of histone proteins. Bahar Edrissi, Koli Taghizadeh, Peter C. Dedon. Massachusetts Institute of Technology, Cambridge, MA.
• Oxidative stress as a target for drug development in prostate cancer. Athanasios Paschos, Gurmit Singh. McMaster University and Juravinski Cancer Centre, Hamilton, ON, Canada.
• Quantitative changes in endogenous DNA damage correlate with conazole mutagenicity and tumorigenicity. Garret B. Nelson, Sharon A. Leavitt, Jeffrey A. Ross. U.S. Environmental Protection Agency, Research Triangle Park, NC.
• RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1. Jongchan Yeo, Rena A. Goodman, Nicole T. Schirle, Peter A. Beal, Sheila S. David. University of California, Davis, CA.
• The metabolism and signaling of the lipid peroxidation product 4-HNE. Gregory P. Tochtrop. Case Western Reserve University, Cleveland, OH.
• The sprouting of triterpenoids that modulate the inflammatory and the antioxidant phase II response. Tonibelle N. Gatbonton-Schwager¹, John Letterio², Greg Tochtrop¹. ¹Case Western Reserve University, Cleveland, OH, ²Case Comprehensive Cancer Center, Cleveland, OH.
• Toward development of a platform to analyze RNA modifications in the translational response of microbial pathogens to chemical mediators of inflammation. Chia-Hua Maggie Ho, Yok Hian Chionh, Clement T.Y. Chan, Sylvie Alonso, Peter C. Dedon. Singapore-MIT Alliance for Research and Technology, Singapore.
• Transcriptional analysis of atrophic gastritis development reveals the molecular details of antralization of the corpus mucosa. Intawat Nookaew¹, Kaisa Thorell², Kuntal Worah², Sven Pettersson³, Henrik Sjovall⁴, Jens Nielsen¹, Samuel Lundin². ¹ Chemistry and Biotechnology, Chalmers, Gothenburg, Sweden, ²Dept. of Biomedicine, Sahlgrenska Academy, Gothenburg, Sweden, ³Karolinska Institute, Stockholm, Sweden, ⁴Dept. of Medicine, Sahlgrenska Academy, Gothenburg, Sweden.
• Unproven thought to be proved by new research in cancer chemistry: Role of energy balance, neuroendocrine factors, diet, environment (social, climatic, and chemical), and spirituality. Suresh Chand Sanchetee, Sr.¹, Shashank Sanchetee, Jr.². ¹Rajasthan Cancer Cure Hospital Private Limited, Jodhpur, Rajasthan, India, ²M.G. Hospital and Medical College, Jaipur, Rajasthan, India.