Poster Session A
Monday, January 31
5:00 p.m.-7:00 p.m.
In alphabetical order, not board assignment order
- A novel mPGES-1 inhibitor with antitumor activity. Hui-Hua Chang, Zuohe Song, Tina Tripp, Lee Wisner, Vijay Gokhale, Chris Hulme, Emmanuelle J. Meuillet. University of Arizona, Tucson, AZ.
- An orange Monascus pigment induced apoptosis on human gastric adenocarcinoma AGS cells. Yunquan Zheng, Xian-Ai Shi, Yanghao Guo. Fuzhou University, Fuzhou, China.
- Caged nitric oxide prodrugs for cancer therapy. Anna E. Maciag1, Joseph E. Saavedra1, Ryan J. Holland2, Lucy M. Anderson2, Larry K. Keefer2. 1 SAIC-Frederick, Frederick, MD,2 NCI-Frederick, Frederick, MD.
- Discovery of SHP-1 enhancer as apoptotic agents through inactivating STAT3. Kuen-Feng Chen1, Jung-Chen Su2, Jui-Wen Huang3, Wei-Lin Chen2, Chun-Yu Liu4, Ann-Lii Cheng1, Pei-Jer Chen1, Chung-Wai Shiau2. 1 National Taiwan University Hospital, Taipei, Taiwan, 2National Yang-Ming University, Taipei, Taiwan, 3Industrial Technology Research Institute, Hsinchu, Taiwan, 4Taipei Veterans General Hospital, Taipei, Taiwan.
- DNA sequence context alters the oxidation chemistry and reactivity of 8-oxoguanine. Kok Seong Lim1, Liang Cui1, Koli Taghizadeh1, John S. Wishnok1, Vladimir Shafirovich2, Nicholas E. Geacintov2, Steven R. Tannenbaum1, Peter C. Dedon1. 1 Massachusetts Institute of Technology, Cambridge, MA, 2New York University, New York, NY.
- Effects of a Mediterranean diet intervention on eicosanoid levels in colon biopsies. Zora Djuric, Jianwei Ren, D. Kim Turgeon, Mack R. Ruffin, IV, Maria Cornellier, Mary Rapai, Ananda Sen, Dean E. Brenner. University of Michigan, Ann Arbor, MI.
- Follicle stimulating hormone receptor and nerve growth factor in postmenopausal epithelial ovarian cancer. Chinmay K. Basu, Asis Mukhopadhyay. Netaji Cancer Research Institute, Kolkata, West Bengal, India.
- Fragment-based design of novel small-molecule inhibitors to selectively disrupt the β-catenin/Tcf protein-protein interactions. Haitao (Mark) Ji. University of Utah, Salt Lake City, UT.
- Fusarochromanone and novel analogs as anticancer agents. Elahe Mahdavian1, Dakota Boston1, Reid Grimes1, Tara Williams-Hart1, Brian Furmanski2, John Clifford3, Brian Salvatore1. 1 Louisiana State University, Shreveport, LA, 2St. Jude Children's Research Hospital, Memphis, TN, 2LSUHSC, Shreveport, LA.
- In vitro and in vivo anticancer activity of a novel synthetic TLR4 activator. Yong-Shiang Lin1, Chao-Hsiung Lin2, Chun-Cheng Lin3, Shu-ling Fu4. 1 Institute of Public Health, National Yang-Ming University, Taipei, Taiwan, 2Department of Life Sciences and Institute of Genome Sciences, National Yang-Ming University, Taipei, Taiwan, 3Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan, 4Institute of Traditional Medicine, National Yang-Ming University, Taipei, Taiwan.
- In vivo imaging of cancer therapy with glucocorticoid-loaded nanoparticles in an experimental model. Anita Gianella1, Peter A. Jarzyna1, Willem J.M. Mulder1, Venkatesh Mani1, Sarayu Ramachandran1, Claudia Calcagno1, Jun Tang1, Gert Storm2, Victor L. Thijssen3, Arjan W. Griffioen3, Zahi A. Fayad1. 1 Mount Sinai School of Medicine, New York, NY, 2Utrecht Institute for Pharmacological Science, Utrech, The Netherlands, 3VUMC-Cancer Center, Amsterdam, The Netherlands.
- Inflammation in TGFβ-mediated carcinogenesis. B.R. Achyut, David A. Bader, Hannah H. Yan, Yanli Pang, Zhaoyang Li, Li Yang. National Cancer Institute, Bethesda, MD.
- Inflammation-mediated nitrosative deamination: RNA is more reactive than DNA and guanosine is more reactive than adenosine. Vasileios Dendroulakis, William M. Deen, Peter C. Dedon. Massachusetts Institute of Technology, Cambridge, MA.
- N6-formylation of lysine: A secondary modification of histone proteins. Bahar Edrissi, Koli Taghizadeh, Peter C. Dedon. Massachusetts Institute of Technology, Cambridge, MA.
- Oxidative stress as a target for drug development in prostate cancer. Athanasios Paschos, Gurmit Singh. McMaster University and Juravinski Cancer Centre, Hamilton, ON, Canada.
- Quantitative changes in endogenous DNA damage correlate with conazole mutagenicity and tumorigenicity. Garret B. Nelson, Sharon A. Leavitt, Jeffrey A. Ross. U.S. Environmental Protection Agency, Research Triangle Park, NC.
- RNA editing changes the lesion specificity for the DNA repair enzyme NEIL1. Jongchan Yeo, Rena A. Goodman, Nicole T. Schirle, Peter A. Beal, Sheila S. David. University of California, Davis, CA.
- The metabolism and signaling of the lipid peroxidation product 4-HNE. Gregory P. Tochtrop. Case Western Reserve University, Cleveland, OH.
- The sprouting of triterpenoids that modulate the inflammatory and the antioxidant phase II response. Tonibelle N. Gatbonton-Schwager1, John Letterio2, Greg Tochtrop1. 1Case Western Reserve University, Cleveland, OH, 2Case Comprehensive Cancer Center, Cleveland, OH.
- Toward development of a platform to analyze RNA modifications in the translational response of microbial pathogens to chemical mediators of inflammation. Chia-Hua Maggie Ho, Yok Hian Chionh, Clement T.Y. Chan, Sylvie Alonso, Peter C. Dedon. Singapore-MIT Alliance for Research and Technology, Singapore.
- Transcriptional analysis of atrophic gastritis development reveals the molecular details of antralization of the corpus mucosa. Intawat Nookaew1, Kaisa Thorell2, Kuntal Worah2, Sven Pettersson3, Henrik Sjovall4, Jens Nielsen1, Samuel Lundin2. 1 Chemistry and Biotechnology, Chalmers, Gothenburg, Sweden, 2Dept. of Biomedicine, Sahlgrenska Academy, Gothenburg, Sweden, 3Karolinska Institute, Stockholm, Sweden, 4Dept. of Medicine, Sahlgrenska Academy, Gothenburg, Sweden.
- Unproven thought to be proved by new research in cancer chemistry: Role of energy balance, neuroendocrine factors, diet, environment (social, climatic, and chemical), and spirituality. Suresh Chand Sanchetee, Sr.1, Shashank Sanchetee, Jr.2. 1Rajasthan Cancer Cure Hospital Private Limited, Jodhpur, Rajasthan, India, 2M.G. Hospital and Medical College, Jaipur, Rajasthan, India.