American Association for Cancer Research

Poster Session A

Poster Session A
Thursday, January 13
11:30 a.m.-2:30 p.m.

In alphabetical order, not board assignment order

  • A composite polymeric/silica nanoparticle smart delivery system for controlled release and targeted intracellular delivery of cytotoxic drugs. S.M. Khaled1, Brandon S. Brown2, Christine Smid3, Alessandro Parodi1, Andrew Bean2, Mauro Ferrari1, Ennio Tasciotti1. 1Methodist Research Institute, 2University of Texas Health Science Center, Houston, TX, 3University of Texas, Austin, TX.
  • A novel double modulation strategy in cancer treatment with chemotherapeutic agent and siRNA: S-1 improves siRNA accumulation and then Bcl-2 knockdown by the siRNA increases chemosensitivity of 5-FU. Tatsuhiro Ishida, Kazuya Nakamura, Yusuke Doi, Naoto Morioyshi, Hiroshi Kiwada. University of Tokushima, Tokushima, Japan.
  • A novel intein-mediated site-specific click conjugation strategy for improved tumor targeting of nanoparticle systems. Andrew Elias, Andrew Tsourkas. University of Pennsylvania, Philadelphia, PA.
  • Biodistribution of polypropylene sulfide nanoparticles in secondary lymphoid organs reveals novel targets for cancer vaccine therapeutics. Iraklis C. Kourtis, Sachiko Hirosue, Stephane Kontos, Melody A. Swartz, Jeffrey A. Hubbell. École Polytechnique Fédérale de Lausanne, Lausanne, Vaud, Switzerland.
  • Carbon nanotubes enhance CpG uptake and potentiate antiglioma immunity. Dongchang Zhao, Darya Alizadeh, Leying Zhang, Wei Liu, Behnam Badie. City of Hope National Medical Center, Duarte, CA.
  • CdSexTe1-x colloidal nanocrystals induce cycle arrest and differentially regulate the expression of cycle-related genes in lung cells. Asli Toylu1, Ozgur Yilmazer Cakmak2, Serdar Ozcelik2. 1Akdeniz University, Antalya, Turkey, 2Izmir Institute of Technology, Urla Izmir, Turkey.
  • Cerenkov radiation energy transfer (CRET) for enhanced optical imaging of high-energy radioisotopes. Robin Dothager, Reece Goiffon, Erin Jackson, Scott Harpstrite, David Piwnica-Worms. Washington University School of Medicine, St. Louis, MO.
  • Controlled release of cytotoxins from targeted nanostructures with tunable core and shell dimensions for imaging and therapeutic delivery. Lily Yun Lin1, Nam S. Lee1, Zhiqiang Xu2, Andreas M. Nystrom3, Darrin J. Pochan4, Jeffery R. Leonard2, Richard B. Dorshow5, Karen L. Wooley1. 1Texas A&M University, College Station, TX, 2Washington University Medical School, St. Louis, MO, 3Karolinska Institutet, Stockholm, Sweden, 4University of Delaware, Newark, DE, 5Covidien Imaging Solution R&D, St. Louis, MO.
  • Discovery of a new targeting peptide for imaging and treatment in breast cancer. Bettina Proneth1, Wouter H.P. Driessen1, Amin Hajitou2, Fernanda I. Staquicini1, Maria Mikhaylova3, Zaver Bhujwalla3, Wadih Arap1, Renata Pasqualini1. 1University of Texas MD Anderson Cancer Center, Houston, TX, 2Imperial College London, London, United Kingdom, 3Johns Hopkins University, Baltimore, MD.
  • DNA-polymer-lipid shelled microbubbles with tunable contrast properties for ultrasound imaging of tumor angiogenesis. Andrew P. Goodwin, Matthew A. Nakatsuka, Emi Nakayama, Mark J. Hsu, Robert F. Mattrey, Sadik C. Esener, Jennifer N. Cha. University of California, San Diego, La Jolla, CA.
  • Dual therapeutic imaging nanovectors for bioresponsive delivery of dexamethasone to tumors. Xiuling Lu, Jin-Ki Kim, Michael Jay. University of North Carolina, Chapel Hill, NC.
  • Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by celluptake selection. Zeyu Xiao1, Etgar Levy- Nissenbaum1, Waturu Aizu1, Jinjun Shi1, Robert Langer2, Omid Farokhzad1. 1Brigham and Women’s Hospital / Harvard Medical School, Boston, MA, 2Massachusetts Institute of Technology, Cambridge, MA.
  • Exploring carbohydrate recognition for selective cancer cell targeting. Mare Cudic, Maria Rodriguez, Nina Bionda, Predrag Cudic. Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL.
  • Genes with bottles: Combined experimental/modeling investigations of dendron-based nanovectors for DNA delivery. Sabrina Pricl1, Paola Posocco1, Maurizio Fermeglia1, Simon P. Jones2, Anna Barnard2, Dave K. Smith2. 1University of Trieste, Trieste, Italy, 2University of York, Heslington, United Kingdom.
  • Gold nanoparticles induce apoptosis of lung epithelium cancer cells by disrupting microtubules network. Diptiman Choudhury, Hirak Kumar Patra, Anjan Kumar DasGupta, Gopal Chakrabarti. University of Calcutta, Kolkata, India.
  • Image-guided and targeted therapy of drug-resistant pancreatic cancer using theranostic nanoparticles. Gee Young Lee1, Lily Yang1, Weiping Qian1, Zehong Cao1, Y Andrew Wang2, Liya Wang1, Weiling He1, Charles A. Staley1, Rosa Hwang3, Hui Mao1. 1Emory University, Atlanta, GA, 2Ocean Nanotech, LLC, Springdale, AR, 3University of Texas MD Anderson Cancer Center, Houston, TX.
  • In vitro and in vivo evaluation of octreotide-PEG-liposomes for MRI. Diane S. Abou1, Ula Woroniecka2, Thomas Ku1, Carl Le1, Bert T. Wolterbeek2, Jason A. Koutcher1, Peter M. Smith-Jones3, Jason S. Lewis1. 1Memorial Sloan-Kettering Cancer Center, New York, NY, 2TU Delft, Delft, ZH, The Netherlands, 3University of Colorado, Denver, CO.
  • Influence of temperatures in siRNA Bcl-2 gold nanorods delivery in leukemia cells. Adela C. Bonoiu1, Zack Wintrob2, Hong Ding1, Paras P. Prasad1, Alice C. Ceacareanu2. 1ILPB, Buffalo, NY, 2School of Pharmacy and Pharmaceutical Sciences, Buffalo, NY.
  • Intracellular fate of carbon nanotubes targeting specific receptors on ovarian cancer cells. Amal Abdulghani, Musaed AlKholief, Reema Zeineldin. Massachusetts College of Pharmacy & Health Sciences, Worcester, MA.
  • Intraoperative detection of fluorescent nanoparticles using a handheld spectroscopic pen device to guide tumor resection. Aaron M. Mohs1, Yiqing Wang1, Michael C. Mancini2, James M. Provenzale1, Sunil Singhal3, Shuming Nie1. 1Emory University, Atlanta, GA, 2Georgia Tech, Atlanta, GA, 3University of Pennsylvania, Philadelphia, PA.
  • Ligand-directed targeting of tumors with self-assembled nanoparticles allows for multimodal imaging and triggered release of therapeutics. Wouter H.P. Driessen, Himtomi Hosoya, Bettina Proneth, Lawrence F. Bronk, Juri G. Gelovani, Wadih Arap, Renata Pasqualini. University of Texas MD Anderson, Houston, TX.
  • MARCO receptor expression in macrophages, dendritic cells, and tumor cells after internalization of carbon nanotubes. Elaine C. Oliveira1, Vania D. R. Silva2, Adriel Moraes2, Rosemeire F. Paula2, Ana Leda Longhini2, Felipe Pradella2, Fotine S. Toscas1, Felipe Von Glehn2, Alessandro S. Farias2, Juliana C. Sartorelli2, Silvia P. Irazusta1, Alfredo C. Peterlevitz2, Helder J. Ceragioli2, Leonilda M. B. Santos2, Vitor Baranauskas2. 1FATEC-SO, Sorocaba, São Paulo, Brazil, 2University of Campinas-UNICAMP, Campinas, São Paulo, Brazil.
  • MUC1 targeted nanoparticle delivery and cytolysis. Pamela E. Constantinou, Brian P. Danysh, Ekaterina Y. Lukianova-Hleb, Dmitri O. Lapotko, Daniel D. Carson. Rice University, Houston, TX.
  • Nanoparticle formulation of Wortmannin as a novel radiosensitizer. Shrirang Karve, Michael Werner, Andrew Wang. University of North Carolina, Chapel Hill, NC.
  • Nanoparticle-induced photocatalytic elimination of HNSCC cells is mediated by autophagy. Stephan Hackenberg, Rudolf Hagen, Norbert H. Kleinsasser. University Hospital Wuerzburg, Wuerzburg, Germany.
  • pH responsive SPIO nanoparticles for tumor imaging. Samuel H. Crayton, Andrew Tsourkas. University of Pennsylvania, Philadelphia, PA.
  • Production of bifunctional sc-Fv antibody-based fusion proteins of IL-2/FU-MK-1(VH-VΚ) and IL-2/FU-MK- 1(VΚ- VH) in Escherichia coli. Suchada Chanprateep1, Mullika Kongchanasombat1, Nawarat Pohthisoon1, Motomu Kuroki2, Masahide Kuroki2. 1Chulalongkorn University, Patumwan, Bangkok, Thailand, 2Fukuoka University, Jonan-Ku, Fukuoka, Japan.
  • Prostate tumor- and T regulatory cell-targeted chemotherapy using novel XPclad nanoparticles containing cisplatin. Rajesh Singh, Shailesh Singh, James W. Lillard, Jr. Morehouse School of Medicine, Atlanta, GA.
  • Surface-enhanced polymer nanoparticles for inhibition of oncogenic microRNA. Christopher J. Cheng, Mark W. Saltzman. Yale University, New Haven, CT.
  • Synthesis and characterization of highly water-dispersible, mesoporous MgFe2O4 nanoassemblies for MRI imaging, hyperthermia, and site-directed drug (doxorubicin) delivery to cervical cancer. Sunil Kumar, Amita Daverey, Dhirendra Bahadur. Indian Institute of Technology, Mumbai, Maharshtra, India.
  • Synthetic nanoparticle-chaperoned urinary biomarkers for noninvasive cancer diagnostics. Gabriel A. Kwong, Geoffrey von Maltzahn, Omar Abudayyeh, Steven Mo, Gayathree Murugappan, Sangeeta N. Bhatia. Massachusetts Institute of Technology, Cambridge, MA.
  • Systemic delivery and antitumor activity of siRNA complexed with single walled carbon nanotubes. D. Lynn Kirkpatrick1, Michelle K. Weiss1, Robert Lemos2, Geoffrey Bartholomeusz2, Saunab Ghosh3, R. Bruce Weisman3. 1Ensysce Biosciences Inc., Houston, TX, 2University of Texas MD Anderson Cancer Center, Houston, TX, 3Rice University, Houston, TX.
  • Targeted breast cancer radiation therapy with gold nanoparticles. Niladri Chattopadhyay1, Zhongli Cai1, Jean-Philippe Pignol2, Brian Keller2, Eli Lechtman3, Reina Bendayan1, Raymond Reilly1. 1Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada, 2Department of Radiation Oncology, Sunnybrook and Women’s Health Sciences Centre, Toronto, ON, Canada, 3Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
  • Targeted gold micelles as CT contrast agents. Ajlan Waheed Al Zaki, Andrew Tsourkas. University of Pennsylvania, Philadelphia, PA.
  • The development of a novel intravital microscopy pharmacokinetics assay for nanoparticle clearance and the discovery of an unknown site of nanoparticle clearance in the peripheral vasculature. Stephen W. Jones1, Joe DeSimone2, James E. Bear1. 1University of North Carolina School of Medicine, Chapel Hill, NC, 2University of North Carolina, Chapel Hill, NC.
  • The effect of manganese on SHSY5Y neuroblastoma cells: Oxidatively induced DNA damage. Donald H. Atha1, Jeffrey A. Schneider1, Adrienne P. Stephenson2, Romonia R. Reams2, Bryant C. Nelson1. 1National Institute of Standards & Technology, Gaithersburg, MD, 2Florida A & M University, Tallahassee, FL.
  • The nanocomplex: PLGA-paclitaxel-Stat3 siRNA effectively enters cancer cells and overcomes tumor drug resistance. Wen-Pin Su1, Fong-Yu Cheng2, Dar-Bin Shieh1, Jang-Yang Chang3, Chen-Sheng Yeh2, Wu-Chou Su1. 1National Cheng-Kung University Medical College and Hospital, Tainan, Taiwan, 2Department of Chemistry, National Cheng-Kung University, Tainan, Taiwan, 3National Institute of Cancer Research, National Health Research Institutes, Tainan, Taiwan.
  • Trackable and targeted phage as positron emission tomography (PET) agent for cancer imaging. Zibo Li1, Qiaoling Jin2, Chiunwei Huang1, Liaohai Chen2, Li-peng Yap1, Hancheng Cai1, Ryan Park1, Peter S. Conti1. 1University of Southern California, Los Angeles, CA, 2Argonne National Laboratory, Argonne, IL.
  • Triggering the release of anticancer drugs from high-loading inorganic nanoparticles with electromagnetic radiation. Lorenzo Berti, Temesgen Woldeyesus, Kit S. Lam, Sandra Sadate, Sebastian Wachsmann-Hogiu. University of California Davis Health System, Sacramento, CA.
  • Tumor targeting by means of nanocarrier geometry. Biana Godin, Srimeenakshi Srinivasan, Jenolyn F. Alexander, Qingpo Li, Xuewu Liu, Mauro Ferrari, Paolo Decuzzi. Methodist Hospital Research Institute, Houston, TX.
  • Tumor-targeted paramagnetic dendrimer nanoclusters. Zhiliang Cheng, Daniel L.J. Thorek, Ching-Hui Huang, Andrew Tsourkas. University of Pennsylvania, Philadelphia, PA.
  • Unique protein complexes and aggregates detected from cancer using a nanoparticle-dynamic light scattering assay. Qun Huo. University of Central Florida, Orlando, FL.
  • Zirconium phosphate nanoparticles uptake in human breast cancer cell line MCF-7. Millie Gonzalez1, Agustin Diaz2, Josie Fuentes4, Nilmarie Ayala4, Carmen Hernandez4, Wieslaw Kosek1, Jorge L. Colon3, and Adriana Baez1. 1Pharmacology Department, University of Puerto Rico School of Medicine, 2Texas A& M University, College Station, Texas, 3Chemistry Department, University of Puerto Rico Rio Piedras, 4Biology Department, University of Puerto Rico
Poster Session A Poster Session B