American Association for Cancer Research

Poster Session B

Poster Session B
Friday, January 14
3:30 p.m.-6:00 p.m.

In alphabetical order, not board assignment order

  • A synthetic enzyme inhibitor of legumain is a novel targeting ligand for nanotherapeutic drug delivery, inhibiting primary tumor growth without systemic toxicity. Debbie Liao1, Ze Liu1, Wolfgang Wrasidlo2, Tingmei Chen1, Yunping Luo1, Rong Xiang3, Ralph Reisfeld1. 1The Scripps Research Institute, La Jolla, California, 2University of California, San Diego, CA, 3Nankai University School of Medicine, Tianjin, China.
  • Area imaging combined with interactive point spectroscopy of optical contrast agents for intraoperative guidance during cancer resection. Michael C. Mancini1, Aaron M. Mohs2, James M. Provenzale2, Shuming Nie2. 1Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA.
  • Bioinspired camouflage and cell-mediated delivery of multifunctional multistage nanoparticles for enhanced biobarrier escape and tumor accumulation. Jonathan Otto Martinez1, Nicoletta Quattrocchi1, Ciro Chiappini2, Xuewu Liu1, Mikhail Kolonin3, Mauro Ferrari1, Ennio Tasciotti1. 1Methodist Hospital Research Institute, Houston, TX, 2University of Texas, Austin, TX, 3University of Texas Health Science Center, Houston, TX.
  • Biovesicles containing iron oxide nanoparticles for breast cancer targeting. Silvia Ferrati1, Aaron Mack2, Brenda Melendez2, Mauro Ferrari2, Rita Serda2. 1University of Texas Health Science Center, Houston, TX, 2Methodist Research Institute, Houston, TX.
  • Chemotherapeutic-containing polymer micelle delivery in a multistage fashion using mesoporous silicon particles. Elvin Blanco1, Takafumi Sangai2, Angela Hsiao1, Sean P. Chislett3, Jonathan O. Martinez1, Silvia Ferrati1, Funda Meric-Bernstam2, Mauro Ferrari1. 1Methodist Hospital Research Institute, Houston, TX, 2University of Texas MD Anderson Cancer Center, Houston, TX, 3University of Texas Health Science Center at Houston, Houston, TX.
  • Combination therapies for ovarian cancer improve lifespan. Yu-Hung Huang1, Kevin Love2, Eddie Eltoukhy2, Robert Langer2, Daniel G. Anderson2, Janet A. Sawicki1. 1Lankenau Institute for Medical Research, Wynnewood, PA, 2Massachusetts Institute of Technology, Cambridge, MA.
  • Combinatorial drug delivery to tumor cells via micellar nanocarriers. Bindhu Madhavi Rayaprolu, Thripthy Chandran, Usha Katragadda, Chalet Tan. Mercer University College of Pharmacy and Health Sciences, Atlanta, GA.
  • Delivery of nanocapsules with apoptotic proteins to cancer cells. Muxun Zhao, Anuradha Biswas, Zhen Gu, Yi Tang. University of California, Los Angeles, Los Angeles, CA.
  • Delivery of siRNA to the mouse lung. Kevin J. Polach, Jeff Sparks, Leslie Wilkinson, Khursheed Anwer, Jason Fewell, Richard Congo, Gregory Slobodkin, Angela Rea-Ramsey, Casey Pence, Majed Matar, Diane McClure, Jennifer Rice, Elaine Brunhoeber. Egen, Inc., Huntsville, AL.
  • Development of a cationic polymer gene delivery system with increased tumor accumulation and improved biodistribution. Janni Mirosevich, Gregoire Cardoen, Brian Burke, Tara Costich, Kevin Sill. Intezyne Technologies, Tampa, FL.
  • Development of a cross-linked, daunorubicin-loaded micelle with superior pharmacokinetics compared to free daunorubucin and with tunable stability. Jonathan Rios-Doria, Tara Costich, Adam Carie, Kevin Sill. Intezyne, Inc., Tampa, FL.
  • Development of multifunctional nanoparticle-based imaging agents at the Imaging Probe Development Center at the National Institutes of Health. Haitao Wu, Biying Xu, Agnieszka Sulima, Nalini Shenoy, Olga Vasalatiy, Sarah Cheal, Gary L. Griffiths. National Heart, Lung, and Blood Institute, Rockville, MD.  
  • Enhanced delivery of chemotherapeutic nanoparticles by depleting host Kupffer cells. Ohara Yusuke, Oda Tatsuya, Yamada Keiichi, Hashimoto Shinji, Akashi Yoshimasa, Ohkohchi Nobuhiro. University of Tsukuba, Tsukuba, Japan.
  • Evaluation of folate-targeted ChemoRad nanoparticle formulation as intraperitoneal chemoradiotherapy for ovarian cancer. Michael E. Werner, Shrirang Karve, Rohit Sukumar, Natalie D. Cummings, Andrew Z. Wang. University of North Carolina School of Medicine, Chapel Hill, NC.
  • Evolution of targeted hepatic therapy and development of intelligent carrier using nanotechnology. Hany F. Sobhi1, Cherif Boutros2, Jamal Uddin1, Nader Hanna2. 1Coppin State University, Baltimore, MD, 2University of Maryland, Baltimore, MD.
  • Factors affecting the pharmacokinetics (PK) and pharmacodynamics (PD) of nanosomal anticancer agents in patients. Whitney P. Caron1, William Zamboni1, Huali Wu1, Paola A. Gehrig1, Gina Song1, Mark D. Walsh1, Suzan K. Hanna1, Suzanne E. Newman1, Alberto Gabizon2, Ramesh Ramanathan3. 1University of North Carolina at Chapel Hill, Chapel Hill, NC, 2Shaare Zedek Medical Center, Jerusalem, Israel, 3TGen, Phoenix, AZ.
  • Imaging superparamagnetic nanoparticles in cells. Tanya Nocera1, Jun Chen2, Christopher Murray2, Gunjan Agarwal1. 1Ohio State University, Columbus, OH, 2University of Pennsylvania, Philadelphia, PA.
  • Intracellular and extracellular glutathione levels modulate the sensitivity of breast cancer cells to silver nanoparticles. Ravi N. Singh1, David L. Carroll2, Steven A. Akman1, Frank M. Torti1, Suzy V. Torti1. 1Wake Forest University School of Medicine, Winston-Salem, NC, 2Wake Forest University, Winston-Salem, NC.
  • Intraoperative detection of breast tumor margins and SpectroPen-guided removal of residual cancer cells using targeted nanoparticle imaging probes. Zehong Cao1, Aaron Mohs1, Weiping Qian1, Malgorzata Lipowska1, Y Andrew Wang2, William C. Wood1, Shuming Nie1, Lily Yang1. 1Emory University School of Medicine, Atlanta, GA, 2Ocean Nanotech, LLC, Springdale, AR.
  • Investigation of ligand surface density and its implications on the active targeting of nanoparticles. Andrew Elias, Andrew Tsourkas. University of Pennsylvania, Philadelphia, PA.
  • Light-activated nanoscissors: Implications in cancer theranostics. Dar-Bin Shieh1, Tsung-Lin Tsai1, Jih Ru Hwu2, Wu-Chou Su3, Wu-Chou Su3. 1National Cheng Kung University, Tainan, Taiwan, 2National Tsing Hua University, Hsinchu, Taiwan, 3National Cheng Kung University Medical Center, Tainan, Taiwan.
  • MMP-activated nanobeacons for optical imaging of tumor invasion. Ian D. McFadden, Aron Parekh, Alissa Weaver, J. Oliver McIntyre, Lynn M. Matrisian. Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN.
  • Multifunctional iron-platinum micelle contrast agents for the specific detection of prostate cancer. Robert M. Taylor1, Dale L. Huber2, Todd C. Monson2, Marco Bisoffi1, Laurel O. Sillerud1. 1University of New Mexico School of Medicine, Albuquerque, NM, 2Sandia National Laboratories, Albuquerque, NM.
  • Multistage nanovectors conjugated to antibody for dual targeting tumor associated macrophages and endothelial cells in orthotopic models of human pancreatic cancer. Kenji Yokoi1, Biana Godin2, Carol J. Oborn1, Jenolyn F. Alexander2, Tony Hu2, Xuewu Liu2, Isaiah J. Fidler1, Mauro Ferrari2. 1University of Texas MD Anderson Cancer Center, Houston, TX, 2Methodist Hospital Research Institute, Houston, TX.
  • Nanodendrons for imaging and drug delivery targeted to the tumor microenvironment. Lynn E. Samuelson, Randy L. Scherer, Kathy J. Carter, E Ashley Dozier, M N. VanSaun, Darryl J. Bornhop, J Oliver McIntyre, Lynn M. Matrisian. Vanderbilt University, Nashville, TN.
  • Next generation of quantum dots for molecular and cellular imaging of cancer. Andrew M. Smith, Shuming Nie. Emory University, Atlanta, GA.
  • NIR-responsive drug release system for combined targeted cancer chemo- and thermotherapy. Zeyu Xiao1, Jinjun Shi1, Jillian Frieder1, Robert Langer2, Omid Farokhzad1. 1Brigham and Women’s Hospital/Harvard Medical School, Boston, MA, 2Massachusetts Institute of Technology, Cambridge, MA.
  • PEG on nanocarriers induces anti PEG IgM production as a result of activation of immune system. Hashiguchi Yuki, Shimizu Tarou, Ichihara Masako, Ishida Tatsuhiro, Kiwada Hiroshi. University of Tokushima, Tokushima, Japan.
  • PLGA nanoparticle vehicle to delivery siRNAs to treat bladder cancer. Darryl T. Martin1, Jingchun Liu1, Jill Steinbach1, Hristos Kaimakliotis1, Guy Manetti1, Kim A. Woodrow2, Marcia Wheeler1, Adam B. Hittelman1, E. Mark Saltzman1, Robert M. Weiss1. 1Yale University, New Haven, CT, 2University of Washington, Seattle, WA.
  • Preclinical development of SNS01-T: A polyethylenimine nanoparticle with significant antitumoral activity in murine models of multiple myeloma. Catherine A. Taylor1, Richard Dondero2, Zhongda Liu1, Terence Tang1, John Lust3, Kathleen Donovan3, John Thompson1. 1University of Waterloo, Waterloo, ON, Canada, 2Senesco Technologies Inc., New Brunswick, NJ, 3Mayo Clinic, Rochester, MN.
  • Preparation, characterization, and in vivo assessment of Gd-albumin and Gd-dendrimer conjugates as intravascular contrast-enhancing agents for MRI. Kido Nwe, Martin W. Brechbiel. National Institutes of Health, Bethesda, MD.
  • Prostate cancer targeted iron oxide nanoparticles via PSMA. Amarnath Mukherjee1, Thomas Darlington2, Richard Baldwin2, Charles Holz2, Prakash Kulkarni1, Theodore L. DeWeese1, Robert H. Getzenberg1, Robert Ivkov1, Shawn E. Lupold1. 1Johns Hopkins University School of Medicine, Baltimore, MD, 2nanoComposix, San Diego, CA.
  • Renally excreted multimodal silica nanoparticles as melanoma-selective therapeutic platforms for nanomedicine. Nicole Burton1, Miriam Benezra2, Evan Phillips2, Oula Penate-Medina2, Michelle Bradbury2. 1City College of New York, New York, NY, 2Memorial Sloan-Kettering Cancer Center, New York, NY.
  • Secondary Cerenkov-induced fluorescent imaging. Daniel L. Thorek, Wassifa A. Bacchus, Jan Grimm. Memorial Sloan-Kettering Cancer Center, New York, NY.
  • Secreted production of bifunctional sc-Fv antibody-based fusion protein of IL-2 and FU-MK-1(VH-VΚ) in Pichia pastoris. Sakorn Anuleechan1, Tanapat Palaga1, Motomu Kuroki2, Masahide Kuroki2, Suchada Chanprateep1. 1Chulalongkorn University, Patumwan, Bangkok, Thailand, 2Fukuoka University, Jonan-Ku, Fukuoka, Japan.
  • Short RNAs go a long way: Combined experimental/multi-scale modeling studies of PAMAM-based dendrimers binding to different siRNAs. Sabrina Pricl1, Paola Posocco1, Maurizio Fermeglia1, Anastasia Malek2, Carlo V. Catapano2, Carlo V. Catapano2. 1University of Trieste, Trieste, Italy, 2IOSI, Bellinzona, Switzerland.
  • Silver nanoparticles: Evaluation of DNA damage, toxicity, and functional impairment in human mesenchymal stem cells. Norbert Kleinsasser, Rudolf Hagen, Stephan Hackenberg. ENT Clinic University of Wuerzburg, Wuerzburg, Germany.
  • Spectroscopy and confocal microendoscopic imaging of quantum dots in tissue and a comparison of different fluorescence quantitation techniques. Elnaz Yaghini, Alexander M. Seifalian, Alexander J. MacRobert. University College London, London, United Kingdom.
  • Surface chemistry regulates mobility of nanocarriers in A549 lung adenocarcinoma lung cells. Caner Unlu, Gulcin Unal, Serdar Ozcelik. Izmir Institute of Technology, Urla Izmir, Turkey.
  • Surface functionalization and surfactant coating mediate the thrombogenicity of carbon nanotubes. Andrew Burke1, Ravi Singh1, David L. Carroll2, John Owen1, Nancy D. Kock1, Roy Hantgan1, Frank M. Torti1, Suzy V. Torti1. 1Wake Forest University School of Medicine, Winston Salem, NC, 2Wake Forest University, Winston Salem, NC.
  • Synthesis and characterization of core/shell Fe3O4/ZnSe fluorescent magnetic nanoparticles for in vivo imaging. Amber A. McBride1, José M. Vargas1, Tosifa Memon1, Yann Fichou1, James R. O’Brien2, Hugh DC Smyth3, Marek Osinski1. 1University of New Mexico, Albuquerque, NM, 2Quantum Design, San Diego, CA, 3University of Texas, Austin, TX.
  • Targeted delivery of indocyanine green and doxorubicin simultaneously loaded poly(lactide-co-glycolide) (PLGA) nanoparticles: An in vitro study. Supriya Srinivasan, Romila Manchanda, Tingjun Lei, Yuan Tang, Anthony McGoron. Florida International University, Miami, FL.
  • Targeting cancer with novel PI3K inhibitor-containing nanoparticles. Ambarish Pandey, Poloumi Sengupta, Bhaskar Roy, Jawahar Kopparam, Michael Oh, Sudipta Basu, Shiladitya Sengupta. Brigham and Women’s Hospital, Boston, MA.
  • The sensitive detection of RNA in single living cells using a newly developed ratiometric bimolecular beacon. Xuemei Zhang1, Antony Chen1, Akash Shah1, Mark Behlke2, Andrew Tsourkas1. 1University of Pennsylvania, Philadelphia, PA, 2Integrated DNA Technologies Inc., Coralville, IA.
Poster Session A Poster Session B