American Association for Cancer Research

Poster Session A

Poster Session A
Friday, November 4
1:00 p.m.-3:00 p.m.

In alphabetical order, not board assignment order

  • 1-methyl-tryptophan improves the CD3+CD56+ subset of cytokine-induced killer cells, Adisak Wongkajornsilp, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok, Thailand
  • 2G8, a TGFβR2 inhibitor, blocks TGF-β signaling and migration in vitro and in vivo in and immunocompetent murine model of pancreatic cancer, Katherine Ostapoff, University of Texas Southwestern, Dallas, Texas, United States
  • A miR-29/Ets2 Regulatory Pathway in Tumor Associated Macrophages Promotes Metastatic Mammary Tumor Progression, Haritha Mathsyaraja, The Ohio State University, Columbus, OH, United States
  • A novel reconstructed metastasis (rMet) model to understand the role of breast cancer stem cells in metastasis, Mukti Parikh, Purdue University, West Lafayette, IN, United States
  • A totally different outcome: TGFβ signaling in cancer epithelial cells, fibroblasts and myeloid cells, Li Yang, NCI, Bethesda, MD, United States
  • Adenosine A2A receptor signaling supports pro-tumorogenic cancer associated fibroblasts, Melanie Mediavilla-Varela, H. Lee Moffitt Cancer Center, Tampa, FL, United States
  • Association of CD8+ and FoxP3+ T cells with mast cells, epithelial dysplasia and tumor differentiation in premalignant and malignant lesions of the lip, Isolde Rojas, College of Dentistry University of Concepcion, Concepcion, Bio Bio, Chile
  • B cells are required for immunosuppressive activity in Ly6Chi monocytes during inflammation initiated by epidermally restricted H-RAS expression, Andrew Gunderson, The Pennsylvania State University, University Park, PA, United States
  • B regulatory cells and the tumor-promoting actions of TNF-α during squamous carcinogenesis, Tiziana Schioppa, Barts Cancer Institute, London, England
  • Basement membrane localized tumor cells are protected from HER2-targeted therapy in vivo, Jason Zoeller, Harvard Medical School, Boston, MA, United States
  • Blocking αVβ3 integrin by an RGD disintegrin impairs VEGF signaling in endothelial cells and inhibits tumor cell migration, Heloisa Selistre-de-Araujo, Universidade Federal de São Carlos, Sao Carlos, SP, Brazil
  • Bone marrow reserve of MSC in untreated advanced breast cancer patients: A reservoir of the disease, Valeria Martinez, Institute for Experimental Biology and Medicine, Buenos Aires, Argentina
  • Cell-extrinsic effects of tumor endoplasmic reticulum stress on myeloid cells, Navin Mahadevan, University of California, San Diego, La Jolla, CA, United States
  • Characterizing the tumor microenvironment in patient-derived cervix xenografts (OCICx), Naz Chaudary, Ontario Cancer Institute/Princess Margaret Hospital/Campbell Family Institute for Cancer Research, Toronto, Ontario, Canada
  • Computational models and microfluidics to understand the interplay between Multiple Myeloma and microenvironment, Zayar Khin, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States
  • Consolidation of the theranostic value of NG2/CSPG4 in soft-tissue sarcomas by unfolding of the prognostic/predictive significance and dissection of its cellular-molecular functions, Pier Andrea Nicolosi, CRO-IRCCS, Aviano, Italy
  • Designing microenvironmental cancer therapies: The role of metabolic heterogeneity, Mark Robertson-Tessi, Moffitt Cancer Center, Tampa, FL, United States
  • Detection of sympathetic innervation and norepinephrine in orthotopic and spontaneously occurring animal models of breast cancer, Kelley Madden, University of Rochester Medical Center, Rochester, NY, United States
  • Different roles of ADAM9D during in vitro cell migration and invasion of prostate tumor cells, Marcia Cominetti, Federal University of Sao Carlos, Sao Carlos, SP, Brazil
  • Differential inhibition of tumor cell proliferation by normal and cancer derived fibroblasts is dependent on the morphological organization and age of the fibroblast monolayer, Hayrettin Guven, Karolinska Institute, Stockholm, Sweden
  • Diffuse large B-cell lymphoma cells promote paracrine NF-kB activation in stromal cells and monocytes/macrophages that is mediated by the hedgehog receptor SMO, Francisco Vega, Department of Hematopathology. UT MD Anderson Cancer Center, Houston, Texas, United States
  • Effect of FAP on tumor growth in cancer mouse models, Lisa Chang, The Wistar Institute, Philadelphia, PA, United States
  • Exosomal transfer of stromal microRNA 21 to ovarian cancer cells increases invasion and migration potential through up-regulation of matrix metalloproteinase 1, Ngai Na Co, University of Texas MD Anderson Cancer Center, Houston, TX, United States
  • Exploring the potential of macrophage-targeted modulation of NF-kappaB for breast cancer therapy, Fiona Yull, Vanderbilt University, Nashville, TN, United States
  • Genetically engineered T cells targeting cancer associated fibroblasts for cancer immunotherapy, Sunitha Kakarla, Baylor College of Medicine, Houston, Texas, United States
  • Halofuginone and the stroma during pancreatic and hepatic tumor progression, Itay Spector, The Hebrew University of Jerusalem, Rehovot, Israel
  • High thymic stromal lymphopoietin (TSLP) levels prevent tumorigenesis in Notch signaling-deficient skin, Shadmehr Demehri, Washington University in St. Louis, St. Louis, MO, United States
  • Host derived Matrix Metalloproteinase-2 controls tumor survival in the metastatic bone microenvironment, Conor Lynch, Moffitt Cancer Center, Tampa, FL, United States
  • How Do Interactions Modulate Heterogeneity In Cancer Progression and Drug Resistance?, Alexander Anderson, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States
  • Human cytomegalovirus infection induces the expression of NF-κB/p65 in the tumor microenvironment of inflammatory breast cancer, Mohamed El-Shinawi, Department of General Surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt, Arab Rep.
  • Identification of stroma-specific targets using primary tumor derived xenograft models, Fu Li, Novartis Institute for Biomedical Research, Cambridge, MA, United States
  • In vivo response to dasatinib in a transplantable mouse model of Philadelphia-chromosome positive acute lymphoblastic leukemia, Eleanor Cameron, Massachusetts Institute of Technology, Cambridge, MA, United States
  • Infiltrated macrophages and cytokines secreted by tumor draining macrophages potentiate motility of inflammatory breast cancer cells, Mona Mohamed, Cairo University, Faculty of Science, Giza, Egypt, Arab Rep.
  • Initial Studies towards the Determination of the Mechanism of NFκB Inhibition by Microsclerodermin A, Esther Guzman, Harbor Branch Oceanographic Institute at FAU, Fort Pierce, FL, United States
  • Interaction between SPARC expressing tumor and stromal cells in promoting EMT phenotype and breast carcinoma aggressiveness, Sabina Sangaletti, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
  • Interstitial fluid flow and Erbβ-2 expression combine to initiate breast cancer cell invasion, Alimatou Tchafa, Drexel University, Philadelphia, PA, United States
  • Investigating prostate cancer tumor-stroma interactions - clinical and biological insights from a mathematical model, David Basanta, H. Lee Moffitt Cancer Center, Tampa, FL, United States
  • JNK promotes intestinal tumor formation in Apc mutant mice through activation of mTOR complex 1 and c-Jun, Masahiro Aoki, Aichi Cancer Center Research Institute, Nagoya, Aichi, Japan
  • Lymphatic invasion of tumor cells and migration of cytotoxic leukocytes depends on matrix remodeling by tumor-associated fibroblasts, Witek Kilarski, EPFL, Lausanne, Switzerland
  • Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs, Qing Chen, Memorial Sloan-Kettering Cancer Center, New York, NY, United States
  • MerTK-mediated efferocytosis controls cytokine production and tumor emergence within the mammary gland, Jamie Stanford, Vanderbilt University, Nashville, TN, United States
  • Molecular profiling of tumor-associated macrophages in melanoma reveals an immunosuppressive and invasive signature, Tao Wang, The Wistar Institute, Philadelphia, PA, United States
  • Multiple roles for Lumican in the tumor microenvironment: Angiogenesis inhibition and suppression of androgen signaling, Allan Albig, Indiana State University, Terre Haute, IN, United States
  • Osteopontin regulates chemokine activity to promote FGFR1-mediated mammary epithelial cell migration, Johanna Reed, University of Minnesota, Minneapolis, MN, United States
  • Ovarian tumor microenvironment: Lymphotoxin initiates tumor-promoting reciprocal interactions between cancer cells and stromal fibroblasts via CXCL10 and CXCL11, Joseph Kwong, The Chinese University of Hong Kong, Hong Kong, China
  • p16INK4A represses breast stromal fibroblast activation and the related paracrine tumor-promoting effects, Abdelilah Aboussekhra, King Faisal specialist Hospital, Riyadh, Saudi Arabia
  • Paracrine interactions in the tumor microenvironment through CXCL1/2 chemokines promote breast cancer metastasis and chemoresistance, Swarnali Acharyya, Memorial Sloan-Kettering Cancer Center, New York, New York, United States
  • Patient-derived tumor grafts authentically reflect tumor pathology, growth, metastasis, and disease outcomes, Alana Welm, University of Utah Huntsman Cancer Institute, Salt Lake City, UT, United States
  • Prostate tumor-infiltrating mast cells induce tolerogenic activity in dendritic cells, Arthur Hurwitz, NCI, Frederick, MD, United States
  • Radiation-amplified drug delivery to angiogenic tumor vasculature via Galectin-1, Meenakshi Upreti, University of Arkansas for Medical Sciences, Little Rock, AR, United States
  • Role for Collagen Organization in the Protective Effect of Parity and Implications for Breast Cancer Dormancy, Ori Maller, University of Colorado Anschutz Medical Campus, Aurora, CO, United States
  • Role of hematopoietic-derived cells in the intestinal tumor microenvironment in response to chemotherapy with Thymidylate Synthase inhibitors in the ApcMin/+ mouse, Grishma Acharya, University Of South Carolina, Columbia, South Carolina, United States
  • Role of HIF-2α in tumor-associated macrophage function and implications for therapy of colitis-associated colon cancer, Jessica Shay, University of Pennsylvania School of Medicine, Philadelphia, PA, United States
  • Signal transducer and activator of transcription 3 (STAT3) plays a contributory role in interleukin-6-mediated drug resistance in neuroblastoma, Tasnim Ara, The Saban Research Institute of Childrens Hospital Los Angeles, Los Angeles, CA, United States
  • Stabilization of the Breast Tumor Microenvironment by HoxD10, Mazen Sidani, University of California, San Francisco, San Francisco, CA, United States
  • Stromal Syndecan-1 promotes extracellular matrix organization and breast cancer metastasis, Colleen Chute, University of Wisconsin-Madison, Madison, WI, United States
  • Sympathetic nervous system regulation of tumor growth in a breast cancer model, Mercedes Szpunar, University of Rochester Medical Center, Rochester, NY, United States
  • Systemic effects of the wound-healing response on tumor recurrence, Jordan Krall, Whitehead Institute for Biomedical Research, Cambridge, MA, United States
  • Targeting myeloid-derived suppressor cells in the tumor microenvironment and lymphoid organs with small drug-loaded nanoparticles, Laura Jeanbart, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland
  • Targeting Tumor Hypoxia in Patient-Derived Pancreatic Xenograft Models Using the Hypoxia-Activated Produg TH-302, Ines Lohse, Princess Margaret Hospital, Toronto, Ontario, Canada
  • The exploration of novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment, Motohisa Tada, Chiba University, Chiba, Japan
  • The Hedgehog inhibitor IPI-926 increases tumor perfusion and enhances drug delivery in a preclinical pancreatic xenograft model, Veronica Campbell, Infinity Pharmaceuticals, Inc., Cambridge, MA, United States
  • The interplay between microenvironment heterogeneity and hypoxia-activated drug dynamics: A computational study, Katarzyna Rejniak, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States
  • The M-CSF/CSF-1R pathway regulates the recruitment of tumor-associated macrophages in mammary carcinogenesis, Debbie Strachan, Novartis Institutes for BioMedical Research, Emeryville, CA, United States
  • The microenvironment decides how prostate tumors respond to castration treatment, Sofia Halin Bergstrom, Department of Medical Biosciences, Umeå University, Umeå, Sweden
  • The role of M1 and M2 macrophages in early mouse mammary tumorigenesis, Pavlina Chuntova, University of Minnesota, Minneapolis, MN, United States
  • The tumor bed effect: Medium dose irradiation of normal tissue enhances growth of subsequently implanted tumor via up-regulation of IL-17A, Jinsil Seong, Department of Radiation Oncology, Yonsei University Health System, Seoul, Korea (Rep.)
  • Tumor associated macrophages and interleukin-6 are associated with in vivo tumor growth and promote in vitro tumor cell proliferation in a novel murine neuroblastoma model, Michael Hadjidaniel, Children's Hospital Los Angeles, Los Angeles, CA, United States
  • Tumor-associated macrophages and stromal TNF-α play central roles in the regulation of collagen structure as visualized by second harmonic generation and immunofluorescence, Ryan Burke, University of Rochester, Rochester, NY, United States
  • Tumor-associated macrophages promote tumorigenesis while retaining Fc-dependent tumoricidal function, Katharine Grugan, Centocor R&D, Inc, Radnor, PA, United States
  • Tumors ceasing the expression of CXCL9/Mig in the microenvironment are resistant to CD8 T cell-mediated immunity, Anton Gorbachev, Cleveland Clinic, Cleveland, OH , United States
  • Zoledronate Nanoparticles Repolarize Neutrophils in Tumor Microenvironment to Impair Growth of Tumors Refractory to Anti Angiogenic Drugs, Sushil Kumar, Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland
Poster Session A Poster Session B