Poster Session A

Poster Session A
Friday, November 4
1:00 p.m.-3:00 p.m.

In alphabetical order, not board assignment order

• 1-methyl-tryptophan improves the CD3⁺CD56⁺ subset of cytokine-induced killer cells, Adisak Wongkajornsilp, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok, Thailand
• 2G8, a TGFβR2 inhibitor, blocks TGF-β signaling and migration in vitro and in vivo in and immunocompetent murine model of pancreatic cancer, Katherine Ostapoff, University of Texas Southwestern, Dallas, Texas, United States
• A miR-29/Ets2 Regulatory Pathway in Tumor Associated Macrophages Promotes Metastatic Mammary Tumor Progression, Haritha Mathsyaraja, The Ohio State University, Columbus, OH, United States
• A novel reconstructed metastasis (rMet) model to understand the role of breast cancer stem cells in metastasis, Mukti Parikh, Purdue University, West Lafayette, IN, United States
• A totally different outcome: TGFβ signaling in cancer epithelial cells, fibroblasts and myeloid cells, Li Yang, NCI, Bethesda, MD, United States
• Adenosine A2A receptor signaling supports pro-tumorogenic cancer associated fibroblasts, Melanie Mediavilla-Varela, H. Lee Moffitt Cancer Center, Tampa, FL, United States
• Association of CD8+ and FoxP3+ T cells with mast cells, epithelial dysplasia and tumor differentiation in premalignant and malignant lesions of the lip, Isolde Rojas, College of Dentistry University of Concepcion, Concepcion, Bio Bio, Chile
• B cells are required for immunosuppressive activity in Ly6C^hi monocytes during inflammation initiated by epidermally restricted H-RAS expression, Andrew Gunderson, The Pennsylvania State University, University Park, PA, United States
• B regulatory cells and the tumor-promoting actions of TNF-α during squamous carcinogenesis, Tiziana Schioppa, Barts Cancer Institute, London, England
• Basement membrane localized tumor cells are protected from HER2-targeted therapy in vivo, Jason Zoeller, Harvard Medical School, Boston, MA, United States
• Blocking αVβ3 integrin by an RGD disintegrin impairs VEGF signaling in endothelial cells and inhibits tumor cell migration, Heloisa Selistre-de-Araujo, Universidade Federal de São Carlos, Sao Carlos, SP, Brazil
• Bone marrow reserve of MSC in untreated advanced breast cancer patients: A reservoir of the disease, Valeria Martinez, Institute for Experimental Biology and Medicine, Buenos Aires, Argentina
• Cell-extrinsic effects of tumor endoplasmic reticulum stress on myeloid cells, Navin Mahadevan, University of California, San Diego, La Jolla, CA, United States
• Characterizing the tumor microenvironment in patient-derived cervix xenografts (OCICx), Naz Chaudary, Ontario Cancer Institute/Princess Margaret Hospital/Campbell Family Institute for Cancer Research, Toronto, Ontario, Canada
• Computational models and microfluidics to understand the interplay between Multiple Myeloma and microenvironment, Zayar Khin, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, United States
• Consolidation of the theranostic value of NG2/CSPG4 in soft-tissue sarcomas by unfolding of the prognostic/predictive significance and dissection of its cellular-molecular functions, Pier Andrea Nicolosi, CRO-IRCCS, Aviano, Italy
• Designing microenvironmental cancer therapies: The role of metabolic heterogeneity, Mark Robertson-Tessi, Moffitt Cancer Center, Tampa, FL, United States
• Detection of sympathetic innervation and norepinephrine in orthotopic and spontaneously occurring animal models of breast cancer, Kelley Madden, University of Rochester Medical Center, Rochester, NY, United States
• Different roles of ADAM9D during in vitro cell migration and invasion of prostate tumor cells, Marcia Cominetti, Federal University of Sao Carlos, Sao Carlos, SP, Brazil
• Differential inhibition of tumor cell proliferation by normal and cancer derived fibroblasts is dependent on the morphological organization and age of the fibroblast monolayer, Hayrettin Guven, Karolinska Institute, Stockholm, Sweden
• Diffuse large B-cell lymphoma cells promote paracrine NF-kB activation in stromal cells and monocytes/macrophages that is mediated by the hedgehog receptor SMO, Francisco Vega, Department of Hematopathology. UT MD Anderson Cancer Center, Houston, Texas, United States
• Effect of FAP on tumor growth in cancer mouse models, Lisa Chang, The Wistar Institute, Philadelphia, PA, United States
• Exosomal transfer of stromal microRNA 21 to ovarian cancer cells increases invasion and migration potential through up-regulation of matrix metalloproteinase 1, Ngai Na Co, University of Texas MD Anderson Cancer Center, Houston, TX, United States
• Exploring the potential of macrophage-targeted modulation of NF-kappaB for breast cancer therapy, Fiona Yull, Vanderbilt University, Nashville, TN, United States
• Genetically engineered T cells targeting cancer associated fibroblasts for cancer immunotherapy, Sunitha Kakarla, Baylor College of Medicine, Houston, Texas, United States
• Halofuginone and the stroma during pancreatic and hepatic tumor progression, Itay Spector, The Hebrew University of Jerusalem, Rehovot, Israel
• High thymic stromal lymphopoietin (TSLP) levels prevent tumorigenesis in Notch signaling-deficient skin, Shadmehr Demehri, Washington University in St. Louis, St. Louis, MO, United States
• Host derived Matrix Metalloproteinase-2 controls tumor survival in the metastatic bone microenvironment, Conor Lynch, Moffitt Cancer Center, Tampa, FL, United States
• How Do Interactions Modulate Heterogeneity In Cancer Progression and Drug Resistance?, Alexander Anderson, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States
• Human cytomegalovirus infection induces the expression of NF-κB/p65 in the tumor microenvironment of inflammatory breast cancer, Mohamed El-Shinawi, Department of General Surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt, Arab Rep.
• Identification of stroma-specific targets using primary tumor derived xenograft models, Fu Li, Novartis Institute for Biomedical Research, Cambridge, MA, United States
• In vivo response to dasatinib in a transplantable mouse model of Philadelphia-chromosome positive acute lymphoblastic leukemia, Eleanor Cameron, Massachusetts Institute of Technology, Cambridge, MA, United States
• Infiltrated macrophages and cytokines secreted by tumor draining macrophages potentiate motility of inflammatory breast cancer cells, Mona Mohamed, Cairo University, Faculty of Science, Giza, Egypt, Arab Rep.
• Initial Studies towards the Determination of the Mechanism of NFκB Inhibition by Microsclerodermin A, Esther Guzman, Harbor Branch Oceanographic Institute at FAU, Fort Pierce, FL, United States
• Interaction between SPARC expressing tumor and stromal cells in promoting EMT phenotype and breast carcinoma aggressiveness, Sabina Sangaletti, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy
• Interstitial fluid flow and Erbβ-2 expression combine to initiate breast cancer cell invasion, Alimatou Tchafa, Drexel University, Philadelphia, PA, United States
• Investigating prostate cancer tumor-stroma interactions - clinical and biological insights from a mathematical model, David Basanta, H. Lee Moffitt Cancer Center, Tampa, FL, United States
• JNK promotes intestinal tumor formation in Apc mutant mice through activation of mTOR complex 1 and c-Jun, Masahiro Aoki, Aichi Cancer Center Research Institute, Nagoya, Aichi, Japan
• Lymphatic invasion of tumor cells and migration of cytotoxic leukocytes depends on matrix remodeling by tumor-associated fibroblasts, Witek Kilarski, EPFL, Lausanne, Switzerland
• Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs, Qing Chen, Memorial Sloan-Kettering Cancer Center, New York, NY, United States
• MerTK-mediated efferocytosis controls cytokine production and tumor emergence within the mammary gland, Jamie Stanford, Vanderbilt University, Nashville, TN, United States
• Molecular profiling of tumor-associated macrophages in melanoma reveals an immunosuppressive and invasive signature, Tao Wang, The Wistar Institute, Philadelphia, PA, United States
• Multiple roles for Lumican in the tumor microenvironment: Angiogenesis inhibition and suppression of androgen signaling, Allan Albig, Indiana State University, Terre Haute, IN, United States
• Osteopontin regulates chemokine activity to promote FGFR1-mediated mammary epithelial cell migration, Johanna Reed, University of Minnesota, Minneapolis, MN, United States
• Ovarian tumor microenvironment: Lymphotoxin initiates tumor-promoting reciprocal interactions between cancer cells and stromal fibroblasts via CXCL10 and CXCL11, Joseph Kwong, The Chinese University of Hong Kong, Hong Kong, China
• p16INK4A represses breast stromal fibroblast activation and the related paracrine tumor-promoting effects, Abdelilah Aboussekhra, King Faisal specialist Hospital, Riyadh, Saudi Arabia
• Paracrine interactions in the tumor microenvironment through CXCL1/2 chemokines promote breast cancer metastasis and chemoresistance, Swarnali Acharyya, Memorial Sloan-Kettering Cancer Center, New York, New York, United States
• Patient-derived tumor grafts authentically reflect tumor pathology, growth, metastasis, and disease outcomes, Alana Welm, University of Utah Huntsman Cancer Institute, Salt Lake City, UT, United States
• Prostate tumor-infiltrating mast cells induce tolerogenic activity in dendritic cells, Arthur Hurwitz, NCI, Frederick, MD, United States
• Radiation-amplified drug delivery to angiogenic tumor vasculature via Galectin-1, Meenakshi Upreti, University of Arkansas for Medical Sciences, Little Rock, AR, United States
• Role for Collagen Organization in the Protective Effect of Parity and Implications for Breast Cancer Dormancy, Ori Maller, University of Colorado Anschutz Medical Campus, Aurora, CO, United States
• Role of hematopoietic-derived cells in the intestinal tumor microenvironment in response to chemotherapy with Thymidylate Synthase inhibitors in the Apc^Min/+ mouse, Grishma Acharya, University Of South Carolina, Columbia, South Carolina, United States
• Role of HIF-2α in tumor-associated macrophage function and implications for therapy of colitis-associated colon cancer, Jessica Shay, University of Pennsylvania School of Medicine, Philadelphia, PA, United States
• Signal transducer and activator of transcription 3 (STAT3) plays a contributory role in interleukin-6-mediated drug resistance in neuroblastoma, Tasnim Ara, The Saban Research Institute of Childrens Hospital Los Angeles, Los Angeles, CA, United States
• Stabilization of the Breast Tumor Microenvironment by HoxD10, Mazen Sidani, University of California, San Francisco, San Francisco, CA, United States
• Stromal Syndecan-1 promotes extracellular matrix organization and breast cancer metastasis, Colleen Chute, University of Wisconsin-Madison, Madison, WI, United States
• Sympathetic nervous system regulation of tumor growth in a breast cancer model, Mercedes Szpunar, University of Rochester Medical Center, Rochester, NY, United States
• Systemic effects of the wound-healing response on tumor recurrence, Jordan Krall, Whitehead Institute for Biomedical Research, Cambridge, MA, United States
• Targeting myeloid-derived suppressor cells in the tumor microenvironment and lymphoid organs with small drug-loaded nanoparticles, Laura Jeanbart, Institute of Bioengineering, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland
• Targeting Tumor Hypoxia in Patient-Derived Pancreatic Xenograft Models Using the Hypoxia-Activated Produg TH-302, Ines Lohse, Princess Margaret Hospital, Toronto, Ontario, Canada
• The exploration of novel strategy for treatment of pancreactic ductal adenocarcinoma targeting tumor microenvironment, Motohisa Tada, Chiba University, Chiba, Japan
• The Hedgehog inhibitor IPI-926 increases tumor perfusion and enhances drug delivery in a preclinical pancreatic xenograft model, Veronica Campbell, Infinity Pharmaceuticals, Inc., Cambridge, MA, United States
• The interplay between microenvironment heterogeneity and hypoxia-activated drug dynamics: A computational study, Katarzyna Rejniak, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States
• The M-CSF/CSF-1R pathway regulates the recruitment of tumor-associated macrophages in mammary carcinogenesis, Debbie Strachan, Novartis Institutes for BioMedical Research, Emeryville, CA, United States
• The microenvironment decides how prostate tumors respond to castration treatment, Sofia Halin Bergstrom, Department of Medical Biosciences, Umeå University, Umeå, Sweden
• The role of M1 and M2 macrophages in early mouse mammary tumorigenesis, Pavlina Chuntova, University of Minnesota, Minneapolis, MN, United States
• The tumor bed effect: Medium dose irradiation of normal tissue enhances growth of subsequently implanted tumor via up-regulation of IL-17A, Jinsil Seong, Department of Radiation Oncology, Yonsei University Health System, Seoul, Korea (Rep.)
• Tumor associated macrophages and interleukin-6 are associated with in vivo tumor growth and promote in vitro tumor cell proliferation in a novel murine neuroblastoma model, Michael Hadjidaniel, Children's Hospital Los Angeles, Los Angeles, CA, United States
• Tumor-associated macrophages and stromal TNF-α play central roles in the regulation of collagen structure as visualized by second harmonic generation and immunofluorescence, Ryan Burke, University of Rochester, Rochester, NY, United States
• Tumor-associated macrophages promote tumorigenesis while retaining Fc-dependent tumoricidal function, Katharine Grugan, Centocor R&D, Inc, Radnor, PA, United States
• Tumors ceasing the expression of CXCL9/Mig in the microenvironment are resistant to CD8 T cell-mediated immunity, Anton Gorbachev, Cleveland Clinic, Cleveland, OH , United States
• Zoledronate Nanoparticles Repolarize Neutrophils in Tumor Microenvironment to Impair Growth of Tumors Refractory to Anti Angiogenic Drugs, Sushil Kumar, Institute of Molecular Cancer Research, University of Zurich, Zurich, Switzerland