American Association for Cancer Research

Poster Session A

Poster Session A
Friday, February 22
5:00 p.m.-7:00 p.m.

(In board assignment order, subject to change)


    CANCER GENOMES AND TUMOR EVOLUTION

  • (A001) NKX2-1/TTF-1 is a context-dependent regulator of lung tumorigenesis, Yutaka Maeda; Jeffrey Whitsett
  • (A002) Imaging and molecular characterization of locally advanced breast cancer , Sharareh Siamakpour-Reihani; Kouros Owzar; Oana Craciunescu; Mark Dewhirst
  • (A003) New mouse models of B-cell lymphoma using an in vitro retroviral transduction system, Kotaro Arita; Shinobu Tsuzuki; Masao Seto
  • (A004) PIK3CA mutation is associated with a favorable prognosis in esophageal squamous cell carcinoma, Hironobu Shigaki; Yoshifumi Baba; Masayuki Watanabe; Keisuke Miyake; Asuka Murata; Nobuyuki Ozaki; Shiro Iwagami; Takatsugu Ishimoto; Masaaki Iwatsuki; Yasuo Sakamoto; Yuji Miyamoto; Naoya Yoshida; Hideo Baba
  • (A005) EPAS1 and HIF1A Germline Variation and Modification of HIF1A/HIF2A Protein Expression in Clear Cell Renal Cell Carcinoma Tumor Tissue Microarray, Lee Moore1; Lauren Hurwitz1; Ruth Pfeiffer1; Petra Lenz1; Purdue Mark1; Mike Nickerson1; W Marston Linehan1; Maria Merino1; Stephen Chanock1; Wong-Ho Chow2; Meredith Yeager1; Nat Rothman1; Stephen Hewitt1; Jorge Toro1
  • (A006) CLCA2, a target of the p53 family, negatively regulates cancer cell migration and invasion, Yasushi Sasaki1; Ryota Koyama1; Reo Maruyama2; Miyuki Tamura1; Tomoko Ohashi1; Masashi Idogawa1; Hiromu Suzuki2; Yasuhisa Shinomura3; Takashi Tokino1
  • (A007) Low expression of tumor suppressor genes were related to poor outcome of childhood acute lymphoblastic leukemia without fusion genes, Kazutoshi Iijima1; Daisuke Hasegawa2; Nobutaka Kiyokawa1; Kenichiro Kobayashi1; Hajime Okita1; Tetsuya Mori3; Takashi Fukushima4; Masahiro Saito5; Katsuyoshi Koh6; Atsushi Manabe2; Akira Kikuchi7; Junichiro Fujimoto8; Yasuhide Hayashi9; Akira Ohara10;
  • (A008) Regulation of the G2 decatenation checkpoint by topoisomerase II (topo II) α and β, Mahrukh K. Ganapathi1; Dale R. Grabowski2; Andrew C.G. Porter3; Andrei-Jose Petrescu4; Marius A. Miculta4; Paul Elson2; Gerald A. Hoeltge2; Ram N. Ganapathi1;
  • (A009) Quantitative analysis of KRAS codon 12 mutation reveals KRAS mutant tumor subpopulations in many adenocarcinomas: Implications for personalized cancer treatment, Meagan B. Myers; Karen L. McKim; Fanxue Meng; Barbara L. Parsons;
  • (A010) Essential oil of Nigella sativa inhibits angiogenesis via down-regulation of VEGF expression, Hussein M. Baharetha; Zeyad D. Nassar; Abdalrahim F. Aisha; MO. Abd Kadir; Zhari Ismail; AMS. Abdul Majid;
  • (A011) Cancer-associated missense mutations of CASP8 activate NF-κB signaling, Mizuo Ando1; Masahito Kawazu1; Toshihide Ueno2; Tatsuya Yamasoba3; Hiroyuki Mano1;
  • (A012) Gain of RIPK2 and loss of PTPRM constitute early events in the pathogenic development of colorectal cancer, Putty-Reddy Sudhir1; Shiu-Ting Lin1; Shung-Haur Yang2; Anna Fen-Yau Li2; Yuan-Tsong Chen1; Yuh-Shan Jou1; Jeou-Yuan Chen1;
  • (A013) Anti-apoptotic function of STK10 mutations among human cancers, Kazutaka Fukumura1; Toshihide Ueno2; Masahito Kawazu1; Hiroyuki Mano1;
  • (A014) Identification of anaplastic lymphoma kinase fusions in renal cancer, Emiko Sugawara1; Yuki Togashi2; Naoto Kuroda3; Seiji Sakata2; Satoko Baba2; Reimi Asaka2; Takeshi Yuasa4; Junji Yonese4; Masanobu Kitagawa5; Hiroyuki Mano6; Yuichi Ishikawa7; Kengo Takeuchi2;
  • (A015) Frequent Partial Deletion/Duplication of BAP1 gene in Malignant Mesotheliomas, Mitsuru Emi1; Hidenori Sato2; Yoshie Yoshikawa3; Tomoko Tamaoki-Hashimoto3; Tohru Tujimura3; Seiki Hasegawa3; Takashi Nakano3;
  • (A016) The human sub-ependymal zone harbors glioblastoma precursors and represents a distinct therapeutic target, Sara Grazia Maria Piccirillo1; Inma Spiteri2; Andrea Sottoriva3; Anestis Touloumis4; Christina Curtis3; John C. Marioni4; Simon Tavare'2; Colin Watts1;
  • (A017) Identification of novel p53 target genes by ChIP-Seq and mRNA expression analysis combined with genome-wide p53-binding motif analysis in silico., Masashi Idogawa; Tomoko Ohashi; Yasushi Sasaki; Takashi Tokino;
  • (A018) Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness, Miyuki Tamura; Yasushi Sasaki; Ryota Koyama; Ikuko Yokota; Tomoko Ohashi; Masashi Idogawa; Takashi Tokino;
  • (A019) Systematic functional identification of driver mutations for individual ovarian cancers, Seiichi Mori1; Takeshi Fujiwara1; Takako Yokomizo1; Haruko Iwase2; Kato Kazuyoshi2; Yukie Nakashima1; Tokuichi Kawaguchi3; Tetsuo Noda1;
  • (A020) 3D nuclear organization of telomeres in breast cancer: towards a new approach to categorize breast cancer, Oumar Samassekou1; Vera Cappelletti2; Valeria Musella2; Sabine Mai1;
  • (A021) Exomic landscape of 97 Japanese lung adenocarcinoma, Katsuya Tsuchihara1; Sachiyo Mimaki1; Koutatsu Matsushima1; Makito Suzuki1; Ayako Suzuki2; Yutaka Suzuki2; Sumio Sugano2; Hiroyasu Esumi1;
  • (A022) Mutational and expressional analyses of DICER1 gene in ovarian stromal tumors and other common tumors, Min Sung Kim; Changhyeok An; Nam Jin Yoo; Sug Hyung Lee;
  • (A023) Three-dimensional nuclear telomeric organization (3D) of chronic myeloid leukemia patients (CML) predicts accelerated phase and blast crisis., Fabio Morato Oliveira1; Macoura Gadji2; Belinda Pinto Simões1; Eduardo Magalhães Rego1; Roberto Passetto Falcão1; Sabine Mai2;
  • (A024) A Functional Variant, rs967591G>A, in the 19q13.3 and Survival of Early-Stage Lung Cancer, Myunghoon Lee1; Hyo-Sung Jeon1; Yi Yong Choi1; Jin Eun Choi1; Shin Yup Lee1; Hyo-Gyoung Kang1; Sanghoon Jheon2; Hyung Kyung Lee3; Sang Mi Han3; Sun Hong Kim3; Hyun Chul Lee1; Jae Yong Park1;
  • (A025) Gene profile related to the inhibitory effects of α-Bisabolol on cellular invasion of pancreas cancer, Yukihiro Yokoyama; Masanori Uno; Toshio Kokuryo; Masato Nagino;
  • (A026) Apoptosis induction in p53-mutated cancer cells by shRNAs based on the screening of genome-wide shRNA library, Tomoko Ohashi; Masashi Idogawa; Jun Sugisaka; Miyuki Tamura; Ikuko Yokota; Yasushi Sasaki; Takashi Tokino;
  • (A027) Whole exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors, Juliann Chmielecki1; Aimee Crago2; Mara Rosenberg3; Rachael O'Connor2; Lauren Ambrogio3; Daniel Auclair3; Aaron McKenna3; Michael Heinrich4; David Frank1; Matthew Meyerson1;
  • (A028) Genome-wide analysis of prostate tumors reveals genetic markers associated with early cancer-specific mortality following prostatectomy, Wennuan Liu1; Christopher Y. Thomas1; Seong-Tae Kim1; Johan Lindberg2; Lars Egevad2; Jielin Sun1; Patrick P. Koty1; Siqun L. Zheng1; G Steve Bova3; Henrik Grönberg2; William B. Isaacs3; Jianfeng Xu1;
  • (A029) Identification of BAP1 as a Predisposing Gene for Malignant Mesothelioma, Masaki Nasu1; Joseph R. Testa2; Harvey I. Pass3; Yang Haining1; Giovanni Gaudino1; Michele Carbone1;
  • (A030) Pharmacological and genomic profiling identifies deregulation of classical and alternative NF-kappaB (NFKB) signaling in Mantle Cell Lymphomas, Rami Rahal1; Mareike Frick2; Rodrigo Romero1; Joshua Korn1; David Ruddy1; Adnan Derti1; Daniel Rakiec1; Tara Naylor1; Audrey Kauffmann3; Estelle Pfister3; Christine Fritsch3; Steve Kovats1; Sunkyu Kim1; Kerstin Dietze2; Bernd Doerken2; Alexander Tzankov4; Michael Hummel2; John Monahan1; Michael Morrissey1; Georg Lenz2; Frank Stegmeier1;
  • (A031) The molecular mechanisms of NPMc-induced acute myeloid leukemia., Yoko Ogawara; Issay Kitabayashi;
  • (A032) Neuropil-like islands in oligoastrocytomas indicates astrocytic molecular pathways., Keisuke Ueki; Fumi Higuchi; Hadzuki Matsuda;
  • (A033) Integrative Genomic Model for Oral Cancer Progression, Li Zhang1; Yi-Jue Zhao2; Alexander Yu2; T-K Man2; Adel El-Naggar1; Pulivarthi H. Rao2;
  • (A034) An analysis of Wnt pathway genes in The Cancer Genome Atlas (TCGA) and association with clinicopathologic characteristics , Thanh H. Dellinger; Charles Warden; Ernest Han; Mark Wakabayashi;
  • (A035) KRAS gene amplification defines a distinct molecular subgroup of gastroesophageal adenocarcinoma that may benefit from combined anti-MEK/AKT therapy., Daniel Catenacci1; Les Henderson1; Peng Xu1; Jon Burrows2; Todd Hembrough2;
  • (A036) Genome-wide Association Scan of Modifier Genes for Colorectal Cancer Risk in Japanese, Hansong Wang1; Daniel O. Stram2; Christopher A. Haiman2; Lynne R. Wilkens1; Gary K. Chen1; Shoichiro Tsugane3; Motoki Iwasaki3; Robert Haile2; Dee W. West4; Polly A. Newcomb5; Laurence N. Kolonel1; Brian E. Henderson2; Suminori Kono6; Loïc Le Marchand1;
  • (A037) Identification and Molecular Characterization of Novel Fusion Transcripts in Never Smoker Lung Adenocarcinoma, Jin Sung Jang; Zhifu Sun; Joanne Yi; Yan W. Asmann; Peter W. Li; Ping Yang; Jin Jen;
    CIRCULATING TUMOR CELLS AND OTHER NEW DIAGNOSTIC TECHNOLOGIES

  • (A038) Identification and characterization of circulating tumor cells (CTCs) using a tagless microfulidic approach, Robert Wieder1; Sri H. Vellanki1; Robin Smith2; Rajan Kumar2;
  • (A039) Measuring the three-dimensional nuclear architecture to detect cancer cells and cancer cell subpopulations, Sabine Mai1; Macoura Gadji1; Julius A. Awe1; Mark C. Xu1; Narisorn Kongruttanachok1; Hans Knecht2;
  • (A040) Multiplexed immunofluorescence imaging and single-cell analysis of MAPK and mTOR signaling in a large cohort of colorectal cancer subjects, Christopher Sevinsky; Yunxia Sui; Alberto Santamaria-Pang; Qing Li; Vidya Kamath; Michael Gerdes; Brion Sarachan; Fiona Ginty;
  • (A041) Unique CTC subpopulations revealed by 3D telomeric analysis, Julius Adebayo Awe1; Mark Chu Xu1; Janine Wechsler2; Naoual Benali-Furet2; Yvon E. Cayre2; Jeff Saranchuk3; Darrel Drachenberg3; Sabine Mai1;
  • (A042) Computer system for clinical sequencing in National Cancer Center, Tokyo, Japan, Mamoru Kato; Hiromi Nakamura; Isao Kurosaka; Yasushi Totoki; Hitoshi Ichikawa; Tatsuji Mizukami; Hiromi Sakamoto; Sumiko Oonami; Shingo Matsumoto; Sachiyo Mimaki; Noboru Yamamoto; Teruhiko Yoshida; Hitoshi Nakagama; Katsuya Tsuchihara; Takashi Kohno; Tatsuhiro Shibata;
  • (A043) Application of multispectral digital colposcopy for the detection of cervical intraepithelial neoplasia, Calum MacAulay1; Sylvia Lam1; Martial Guillaud1; Deanna Ceron1; Judit Banáth1; Jagoda Korbelik1; Dennis D. Cox2; E. Neely Atkinson3; Roderick Price4; Timon P H Buys1; J Salvador Saldivar5; Kayla Castaneda5; Harvey Greenberg5; Sarah Finlayson6; Mark Heywood6; Janice Kwon6; Marette Lee6; Jessica McAlpine6; Tom Ehlen6; Dianne Miller6; Dirk van Niekerk7; Pierre Lane1; Michele Follen5;
  • (A044) Quantitative glycoproteomics of hepatocellular carcinoma, Miloslav Sanda; Petr Pompach; Zuzana Brnakova; Julius Benicky; Jing Wu; Yon Changsuek; Radoslav Goldman;
  • (A045) Development of an Asian-specific breast cancer prognostic and predictive signature for stratified medicine., Christopher W. Wong1; Huaien Luo1; Yang Sun Chan1; Geraldine Nai1; Niranjan Nagarajan1; Krishna Karaturi1; Lance D. Miller2; Soo Chin Lee3;
  • (A046) A Novel Fully Automated Molecular Diagnostic System for Colorectal Cancer mutation detection, Shiro Kitano1; Masahiko Amano1; Mark J. Ratain2;
  • (A047) Circulating microRNAs in the serum of patients with oral cancer and precancer, Sara MacLellan; James Lawson; Catherine Poh; Cathie Garnis;
  • (A048) In situ mutation detection in cancer tissue sections for research and diagnostics in clinical oncology , Ida Grundberg; Sara Kiflemariam; Juliana Imgenberg-Kreuz; Karolina Edlund; Patrick Micke; Magnus Sundstrom; Johan Botling*; Mats Nilsson*;
    NONCODING RNAS

  • (A049) Up-regulation of miR-182 by beta-catenin in breast cancer increases invasiveness by targeting the matrix metalloproteinase inhibitor RECK, Chi-Hsiang Chiang1; Ming-Feng Hou2; Wen-Chun Hung3;
  • (A050) Serum microRNA expression profile: miR-1246 as a novel diagnostic and prognostic biomarker for esophageal squamous cell carcinoma, Nobuyoshi Takeshita; Isamu Hoshino; Mikito Mori; Yasunori Akutsu; Naoyuki Hanari; Yuka Isozaki; Tetsuro Maruyama; Naoki Akanuma; Hisahiro Matsubara;
  • (A051) Mir-27b and their targets genes promote cisplatin resistance of epithelial ovarian cancer cells, Ileabett M. Echevarria Vargas1; Fatma Valiyeva2; Pablo Vivas Mejía1;
  • (A052) miR-134 targeting WWOX enhanced the oncogenicity of oral carcinoma, Chung Ji Liu1; Kuo Wei Chang2; Shu Chun Lin2;
  • (A053) The microRNA miR-516a-3p regulates the Wnt pathway by targeting extracellular sulfatase1 in human scirrhous gastric cancers: Its application for anti-metastatic therapy, Yoshifumi Takei1; Kazuyoshi Yanagihara2;
  • (A054) miR-655 is an EMT-suppressive microRNA targeting ZEB1 and TGFBR2, Yosuke Harazono; Tomoki Muramatsu; Hironori Endo; Narikazu Uzawa; Tatsuyuki Kawano; Ken-ichi Kozaki; Kiyoshi Harada;
  • (A055) Tumor-associated-macrophage induces CD44 expression via miR-328 suppression and promotes cancer progression, Takatsugu Ishimoto1; Masayuki Watanabe1; Nobuyuki Ozaki1; Masaaki Iwatsuki1; Yoshifumi Baba1; Naoya Yoshida1; Osamu Nagano2; Hideyuki Saya2; Hideo Baba1;
  • (A056) Analysis of microRNA-181a in colorectal cancer, Junichi Nishimura; Hirofumi Yamamoto; Hata Taishi; Yuichiro Doki; Masaki Mori;
  • (A057) Widespread inference of weighted microRNA-mediated gene regulation in cancer transcriptome analysis, Suzuki I. Hiroshi; Mihira Hajime; Watabe Tetsuro; Sugimoto Koichi; Miyazono Kohei;
  • (A058) Carcinoid tumors of the lung and gastrointestinal tracts show common microRNA expression profiles, different from adeno- and small cell carcinomas, suggesting a common origin of systemic carcinoids, Toyoki Yoshimoto1; Noriko Motoi1; Noriko Yamamoto1; Masaru Ushijima2; Masaaki Matsuura2; Sakae Okumura3; Toshiharu Yamaguchi3; Masashi Fukayama4; Yuichi Ishikawa1;
  • (A059) BRCA1 regulates Epidermal Growth Factor Receptor (EGFR) expression through transcriptional activation of microRNA-146a, Easwari Kumaraswamy1; Laura A. Augustine1; Shane R. Stecklein1; Karen L. Wendt1; Sumedha Gunewardena2; Roy A. Jensen1;
  • (A060) Fully automated dual detection of medically valuable miRNA and protein pairs in intact tumor samples, Adrian Murillo; Judy Ray; Noah Theiss; Taylor Shingler; Esteban Roberts;
  • (A061) Downregulation of miR-140 Promotes DCIS Stem Cell Formation, Qun Zhou; Yuan Yao; QingLin Li; Gabriel Eades;
  • (A062) miRNA sequencing identifies miRNAs that differentiate histology and distinguish tumor from non-malignant tissue in NSCLC, Larissa A. Pikor; Kelsie L. Thu; Emily A. Vucic; Varune Rohan Ramnarine; Stephen Lam; Wan L. Lam;
  • (A063) Patterns of miRNA disruption specific to smoking and cancer in non-malignant and malignant lung tissues, Emily A. Vucic; Kelsie L. Thu; Larissa A. Pikor; Katey S.S. Enfield; Varune R. Ramnarine; Stephen Lam; Wan L. Lam;
  • (A064) MiRNA-34a delivery through chitosan nanoparticles inhibits prostate tumor growth in the bone, Sanchaika Gaur; Gary E. Gallick;
  • (A065) In vitro live imaging of epithelial to mesenchymal transition using molecular beacon conjugated nanoparticle, Woo Kyung Moon; YoonSeok Choi;
  • (A066) Understanding the potential role of miR-21 and miR-31 in organotropic metastasis of lung cancer, Arvind K. Singla1; Michela Garofalo2; Gerard J. Nuovo2; Frank R. Jirik1;
    OTHER

  • (A067) A new diagnostic biomarker for prostate cancer patients revealed by 2DICAL, Masaya Ono; Masahiro Kamita; Tesshi Yamada;
  • (A068) Effective synergistic drug combinations for the splicing modulator Sudemycin D1 as determined by in vitro antiproliferative effects on tumor cells, Gustavo A. Palacios; Lagisetti Chandraiah; Tinopiwa Goronga; Webb R. Thomas;
  • (A069) CDK4 and CDK6 are mediators of p27/KIP1 and p21/CIP1 degradation through the SKP2 ubiquitin protein ligase in G1 phase, Amin Ismail; Liana Toia; Tony Godfrey;
  • (A070) Outcome of Japanese patients with triple-negative breast cancer receiving neoadjuvant chemotherapy, Katsuya Nakai; Yoshiya Horimoto; Yimit Alkam; Koji Senuma; Hiroyuki Mitomi; Mitsue Saito;
  • (A071) DNA mismatch repair deficiency in ampullary carcinoma: Potential prognostic factor for overall survival?, Susan J. Hsiao; Helen Remotti;
  • (A072) Environmental contaminant bisphenol A toxicity study in Swiss albino mice model,
  • (A073) Multidimensional approach to target identification of new antitumor compounds, Yushi Futamura; Makoto Muroi; Hiroyuki Osada;
  • (A074) UBXN2A Interferes with the p53-Mortalin2 Interaction in Cancer Cells and Constitutes a Potential Target for Cancer Therapy, Khosrow Rezvani;
  • (A075) Relationships between CD133 and ABCG2 as a cancer stem cell marker in various cancer cells, Jeonghoon Heo1; Eun-Kyung Ahn1; Sun-Hee Leem2;
  • (A076) Prognostic factors for persistent trophoblastic disease after hydatidiform mole: a retrospective observational study, Momo Kan; Eiko Yamamoto; Yoko Miwa; Kaoru Niimi; Kanako Shinjo; Makiko Higashi; Fumitaka Kikkawa;
  • (A077) Induction of Apoptosis in Colon Cancer Cells by UBXN2A through a p53-Dependent Pathway, Sanam Sane; Dong Zhang; Khosrow Rezvani;
  • (A078) MUC expression of mucinous cancer in breast, colon, pancreas and ovary., Tousei Ohmura1; Tomoko Takamaru1; Goro Kutomi1; Hiroaki Shima1; Hidekazu Kameshima2; Fukino Satomi1; Yasuyo Suzuki1; Tomohisa Furuhata1; Koichi Hirata1; Kunihiko Ishitani2;
  • (A079) Synthesis, Anti-proliferative, Anti-migratory, and Anti-invasive Properties of Novel Sugar Mimetic Isoxazolines against Malignant Cancer cells In Vitro, D S. Prasanna1; M P. Sadashiva2; Basappa3; S Nanjundaswamy4; Gautam Sethi4; Kazuyuki Sugahara5; K S. Rangappa2;
  • (A080) Redirected antitumor activity of an engineered Sendai virus vector in ovarian cancer cells., Kosei Hasegawa1; Akiko Miyara1; Tatsuya Hanaoka1; Akira Kurosaki1; Yasuji Ueda2; Makoto Inoue2; Mamoru Hasegawa2; Keiichi Fujiwara1;
  • (A081) Apollon binds cyclin A and promotes degradation in early mitosis independent of spindle assembly checkpoint, Nobumichi Ohoka1; Hirokazu Ohata2; Mikihiko Naito1;
  • (A082) The Root Bark of Paeonia moutan and the roots of Scutellaria baicalensis are Potential Anticancer Agents in Human Oral Squamous Cell Carcinoma Cells, Satoru Shintani1; Chunnan Li2; Daisuke Sato1; kazunaga Yazawa3; Seiji Kondo1; Yoshiki Mukudai1; Yuji Kurihara1;
  • (A083) Drivers? of translational cancer epidemiology: a cross-sectional analysis of the literature and NCI grants, Tram Kim Lam; Christine Q. Chang; Muin J. Khoury; Sheri D. Schully;
  • (A084) Preventive effect of chrysin against methotrexate-induced nephrototoxicty, oxidative stress and apoptosis: Probable role of p53 down regulation and caspases expression, Nemat Ali; Sarwat Sultana
  • (A085) Inactivation of Runx3 is prerequisite for K-Ras-induced lung adenocarcinoma, Suk-Chul Bae1; You-Soub Lee1; Jung-Won Lee1; Yoshiaki Ito2;
  • (A086) Destabilization of FLICE-like inhibitory protein long (FLIPL), an anti-apoptotic and anti-necrotic protein, through ubiquitin-proteasome system by a stop codon read-through mutation, Norihito Shibata1; Nobumichi Ohoka1; Yoshiyuki Sakuraba2; Yoichi Gondo2; Mikihiko Naito1;
  • (A087) Androprostamine: A New Antitumor Agents for Androgen-Dependent Prostate Cancer, Yohko Yamazaki; Tohru Masuda; Manabu Kawada; Isao Momose; Akio Nomoto;
  • (A088) Low dose dacarbazine-doxorubicin therapy against intra-abdominal desmoid tumor, Masayuki Hiraki; Hirofumi Yamamoto; Mamoru Uemura; Naotsugu Haraguchi; Junichi Nishimura; Taishi Hata; Ichiro Takemasa; Tsunekazu Mizushima; Yuichiro Doki; Masaki Mori;
  • (A089) The efficiency of portal venous port-catheter system as a route of siRNA delivery for the pancreatic liver metastasis, Toshio Kokuryo; Yukihiro Yokoyama; Masato Nagino;
  • (A090) Distinct phosphorylation of the retinoblastoma protein at serine 612 in differentiated cells, Takayuki Hattori1; Chiharu Uchida2; Hirotaka Takahashi3; Naoki Yamamoto3; Mikihiko Naito1; Yoichi Taya3;
  • (A091) Telomeric protein TRF1 is required for proper chromosome segregation, Tomokazu Ohishi; Yukiko Muramatsu; Hiroyuki Seimiya;
  • (A092) MUC expression profiles for pure-type mucinous carcinoma of the breast, Tomoko Takamaru1; Tousei Ohmura2; Hiroyuki Takamaru1; Fukino Satomi1; Hiroaki Shima1; Goro Kutomi1; Yasuyo Suzuki1; Koichi Hirata1;
  • (A093) Classification of breast cancer subtypes using lasso clustering method, Masaru Ushijima1; Shinto Eguchi2; Osamu Komori2; Yoshio Miki1; Masaaki Matsuura1;
  • (A094) Thymidylate synthase expression as a novel predictive factor in metastatic breast cancer patients, Hirohito Seki1; Hiromitsu Jinno2; Tetsu Hayashida2; Maiko Takahashi2; Asanuma Fumiki1; Yuko Kitagawa2;
  • (A095) Investigating the anticancer activity of sphingosine-1-phosphate against human breast cancer., Jian Yang1; Binbing Ling1; Huihua Zhang2; Ahlam Sultan1; Baohua Ma3; Jane Alcorn1;
  • (A096) PML-RARα disrupts PML nuclear bodies by inhibiting PML oligomerization, Yutaka Shima; Issay Kitabayashi;
  • (A097) Cancer cDNA resequencing with an exon-capture system, Toshihide Ueno; Yoshihiro Yamashita; Manabu Soda; Hiroyuki Mano;
  • (A098) The efficacy and safety of fondaparinux on the prevention of post-operative venous thromboembolism (VTE) in patients undergoing with laparoscopic colorectal cancer surgery, Taishi Hata; Koji Munakata; Naotsugu Haraguchi; Mamoru Uemura; Junichi Nishimura; Ichiro Takemasa; Tsunekazu Mizushima; Hirofumi Yamamoto; Yuichiro Doki; Masaki Mori;
  • (A099) Genetic Reconstitution of Tumorigenesis in Murine Primary Intestinal Cells, Yoshitaka Hippo; Hitoshi Nakagama;
  • (A100) Ectopic chromosome around centrosome (ECAC) in metaphase cells of oropharyngeal carcinoma as a marker of HPV-association, Reiko FURUTA1; Takashi TOSHIYASU2; Yukiko SATO1; Noriko YAMAMOTO1; Futoshi AKIYAMA1; Yuichi ISHIKAWA1; Wataru SHIMBASHI2; Kazuyoshi KAWABATA2; Nobuhiro TAKESHIMA2; Sachiko SUGAI2; Yoshio MIKI2; Tomoyuki KITAGAWA1;
  • (A101) Prognostic values of histopathological findings of HPV-associated oropharyngeal carcinoma, Hideaki Takahashi; Koji Okudera; Hiroshi Hyakusoku; Chihiro Horii; Daisuke Sano;
  • (A102) Involvement of fatty infiltration in pancreatic cancer in humans and animals, Mami Takahashi1; Mika Hori1; Nobuyoshi Hiraoka1; Taiki Yamaji2; Michihiro Mutoh1; Yae Kanai1; Hitoshi Nakagama1;
  • (A103) Expression of E-cadherin and KRAS mutation may be biomarker of Cetuximab-based therapy in metastatic colorectal cancer, Hisashi Nagahara1; Kentaro Nakamoto1; Kiyoshi Maeda1; Hiroshi Ohtani1; Eiji Noda1; Masatsune Shibutani1; Toru Inoue2; Takahiro Toyokawa1; Naoshi Kubo1; Hiroaki Tanaka1; Kazuya Muguruma1; Yukio Nishiguchi2; Masaichi Ohira1; Kosei Hirakawa1;
  • (A104) Identification of Differentially Expressed Genes in Bladder Cancer Cells Treated with Fusarochromanone using DNA Microarray Analysis, qRT-PCR and Sequence Analysis, Phoebe Rollyson1; Trey King1; Mickeal Key1; John Clifford2; Jennifer Roberts Gill2; Elahe Mahdavian1; Urska Cvek1; Brian Salvatore1; Brian Furmanski3; Marjan Trutschl1; Robert Rhoads2; Tara Williams-Hart1;
  • (A105) Controlled insertional mutagenesis using a LINE-1 (ORFeus) gene trap mouse model, Kathryn A. O'Donnell1; Wenfeng An2; Christina T. Schrum3; Edward S. Davis3; Sarah J. Wheelan3; Jef D. Boeke3;
  • (A106) Exploiting metabolic addiction in HER2/neu-positive breast cancer, Jan Martin Baumann; Antonis Kourtidis; Douglas S. Conklin;
  • (A107) Retinoic acid-induced binding of pRb is associated with transcriptional downregulation of the MYCN promoter in neuroblastoma, Masahiro Yoshioka; Kenneth Takeuchi; Randal Wada;
  • (A108) Pre-Clinical and Clinical Evaluation of the Pharmacogenetic Impact on Metabolism and Cytochrome P450 (CYP) 3A Inductive Effect of Tamoxifen, Pankaj Desai; Ganesh Mugundu;
  • (A109) Serial non-invasive evaluation of 2-hydroxyglutarate by 1H-MR spectroscopy (MRS) demonstrates fidelity as a dynamic biomarker and generates novel insights into glioma biology., Elizabeth Maher; Sandeep Ganji; Akshay Madan; Craig Malloy; Robert Bachoo; changho choi;
    SIGNALING AND SYSTEMS BIOLOGY

  • (A110) Identification of distinct residues within the PI3K protein p85α that mediate binding to PTEN and Rab5, Paul Mellor1; Xuan Ruan1; Deborah Anderson2;
  • (A111) Prostate cancer cells and bone stromal cells mutually interact with each other through BMP-mediated signals, Shogo Ehata; Hikaru Nishimori; Suzuki I. Hiroshi; Miyazono Kohei;
  • (A112) Deficiency of PML tumor suppressor retards growth of hippocampal ANPC, Kun-Sang Chang; Wenxin Zou; Mingguang Liu; Kenneth Wang;
  • (A113) Metformin enhances cytotoxicity by suppressing ROS,IL6-Stat3 activity independently of the LKB1?AMPK pathway , Chien-Chung Lin;
  • (A114) RNA Debranching Enzyme (DBR1) is a wtp53 Target under Hypoxia and Maintains RNA Processing, Hwan Park1; Jun Zhang2; Hui Tian3; Denchen Fu1; Peiwen Fei1;
    TARGETED THERAPIES AND RESISTANCE

  • (A115) Predictive values of gemcitabine-sensitivity-related gene products for gemcitabine treatment alone against unresectable or recurrent biliary tract cancer, Akihiro Murata; Ryosuke Amano; Kenjiro Kimura; Bunzo Nakata; Yoshihiro Okita; Hisashi Nagahara; Eiji Noda; Naoshi Kubo; Hiroaki Tanaka; Kazuya Muguruma; Hiroshi Otani; Masakazu Yashiro; Kiyoshi Maeda; Masaichi Ohira; Kosei Hirakawa;
    CANCER PREVENTION

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