American Association for Cancer Research

Poster Session B

Poster Session B
Saturday, February 23
5:00 p.m.-7:00 p.m.

(In board assignment order, subject to change)


    CANCER PROGRESSION AND METASTASIS

  • (B001) Regulatory mechanism of integrin β1 expression in collectively migrating cancer cells, Takuya Kato; Atsushi Enomoto; Masato Asai; Naoya Asai; Masahide Takahashi;
  • (B002) The correlation of decorin and periostin indicated by the proteomics of phyllodes, Toshiyuki Ishiba; Akira Nakanishi; Kenichi Sugihara; Yoshio Miki;
  • (B003) The relation of LINE methylation level and macroscopic type in colorectal adenoma and pT1 colorectal cancer, Katsuhiko Nosho1; Miki Ito1; Takafumi Naito1; Hisayoshi Igarashi1; Yasutaka Sukawa1; Eiichiro Yamamoto1; Reo Maruyama2; Shinji Yoshii3; Masashi Mikami1; Taiga Takahashi1; Yasushi Adachi1; Wakana Sumioka1; Mayumi Nakazawa1; Hiromu Suzuki2; Hiroyuki Yamamoto1; Kohzoh Imai4; Yoshifumi Baba5; Shuji Ogino6; Yasuhisa Shinomura1;
  • (B004) Evaluation of the Role of Transcriptional Repressor DAXX in Autophagy and Pathogenesis of Prostate Cancer, Lorena A. Puto; Tony Hunter;
  • (B005) PLAGL2 regulates actin stress fiber formation and cell migration, Ryuichiro Sekiya; Takeshi Senga; Hiroaki Kajiyama; Kiyosumi Shibata; Fumitaka Kikkawa;
  • (B006) BART inhibits pancreatic cancer cell motility and invasion by Rac1 inactivation through direct binding to active forms of Rac1, Keisuke Taniuchi; Kunihiko Yokotani; Toshiji Saibara;
  • (B007) Podoplanin/aggrus-bound CCL21 on mesothelia regulates peritoneal dissemination, Iwata Caname; Miyazono Kohei;
  • (B008) Activation of Wnt/β-catenin signal pathway by CYP1B1 expression in MCF7 human breast cancer cells, Young-Jin Chun1; Yeo-Jung Kwon1; Nahee Park1; Hee-Jung Im Im1; Donghak Kim2;
  • (B009) Induction of Wnt/β-catenin signal pathway and epithelial-mesenchymal transition (EMT) by steroid sulfatase expression in human prostate cancer cells, Young-Jin Chun1; Hee-Jung Im1; Yeo-Jung Kwon1; Nahee Park1; Donghak Kim2;
  • (B010) Undifferentiated state induced by Rb inactivation associated with metabolic reprogramming and inflammation, Shunsuke Kitajima; Chiaki Takahashi;
  • (B011) Roles of miRNAs in the switch of TGF-β from tumor suppressor to pro-oncogenic factor in cancer progression, Yoshiko Nagano; Binwu Tang; Misako Sato; Maxwell P. Lee; Anand S. Merchant; Parthav Jailwala; Eric A. Stahlberg; Lalage M. Wakefield;
  • (B012) Characterization of Interleukin-β in Helicobacter pylori-induced Gastric Inflammation and DNA Methylation in IL-1 Receptor Type 1 Knockout (IL-1R1-/-) Mice, Fung-Yu Huang1; Annie On-On Chan1; Regina Check-Lam Lo1; Asif Rashid2; Danny Ka-Ho Wong1; Chi-Hin Cho3; Ching-Lung Lai1; Man-Fung Yuen1;
  • (B013) Akt activation promotes the development of brain metastases in a mouse model of melanoma, Matthew W. VanBrocklin; James P. Robinson; Sheri L. Holmen;
  • (B014) Prospero homeobox 1 promotes epithelial-mesenchymal transition in colon cancer cells by inhibiting E-cadherin via miR-9, Mei-Ren Pan; Wen-Chun Hung;
  • (B015) Fascin expression in esophageal squamous cell carcinoma, Naoki Akanuma; Isamu Hoshino; Yasunori Akutsu; Takanori Nishimori; Naoyuki Hanari; Mikito Mori; Kentaro Murakami; Satoshi Endo; Yuka Isozaki; Nobuyoshi Takeshita; Tetsuro Maruyama; Takeshi Toyozumi; Hisahiro Matsubara;
  • (B016) The microRNA -23b/ -27b cluster suppresses the metastatic phenotype of castration-resistant prostate cancer cells, Reema A. Ishteiwy; Toby M. Ward; Derek M. Dykxhoorn; Kerry L. Burnstein;
  • (B017) Sp-1?dependent miR-630 induction by ANGPTL1/integrin α1β1 axis represses Slug expression and cancer metastasis, Tsang-Chih Kuo1; Min-Liang Kuo2;
  • (B018) The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes tumor invasion and metastasis, Kuo-Tai Hua; Min-Liang Kuo;
  • (B019) MafK mediates tumorigenic potential and EMT in breast cancer cells, Yukari Okita; Hiroyuki Suzuki; Mitsuyasu Kato;
  • (B020) Proteomic profiling of metastatic renal cell carcinoma reveals Galectin-1 as a new player in the mTOR signaling axis with potential prognostic significance and therapeutic applications, Nicole MA White1; Olena Masui2; Daniel Newsted1; Leroi DeSouza2; Olga Krakovska2; Ajay Matta2; Alexander Romaschin3; R. John Honey4; Robert Stewart4; Kenneth Pace4; KW Michael Siu2; George Yousef1;
  • (B021) Intramembrane cleavage of heme oxygenase-1 by signal peptide peptidase promotes cancer progression, Fu-Fei Hsu; Yu-Jun Sun; Ming-Tsai Chiang; Wendy Su; Lee-Young Chau;
  • (B022) Transforming mutations of RAC guanosine triphosphatases, Masahito Kawazu1; Toshihide Ueno2; Hiroyuki Mano2;
  • (B023) Snail mediates NSCLC invasion through indirect upregulation of SPARC, Jeanette L. Grant1; Tonya C. Walser1; Long-Sheng Hong1; John D. Minna2; Jerry Shay2; Michael C. Fishbein1; Steven M. Dubinett1;
  • (B024) Expression of PROM1 in advanced lung cancer: No difference could be found between primary tumor lesions and its corresponding metastatic tumor lesions, Tomoe Lu1; Bungo Furusato1; Yoshihiro Lu2; Kazumasa Komine1; Yujin Koike1; Miyuki Kato1; Masahiro Ikegami1; Hiroshi Hano1;
  • (B025) Prognostic significance of CD133 expression in colorectal cancer, Jae Im Lee; Sang Chul Lee; Hyung Jin Kim; Seung Tack Oh; Seung Jin Yoo; Chang Hyoek An;
  • (B026) Increased cytoplasmic CDC25A and CDC25C phosphatases in cutaneous squamous cell carcinoma associated with 14-3-3 relocalization, Jenan A. Almatouq; Laura A. Hansen;
  • (B027) Functional characterization of CD70, a biomarker specific for clear cell renal cell carcinoma, Melanie Ruf; Christiane Fieger; Markus Rechsteiner; Holger Moch; Peter Schraml;
  • (B028) Mdm2 splice variant protein products promote tumorigenesis, disrupt mammary tissue architecture, and are endogenously expressed in cancers, Danielle Okoro1; Nandini Kundu1; Chong Gao1; Cindy Puente2; Alla Polotskaia2; Nicoleta Arva3; Melissa Rosso1; Jill Bargonetti1;
  • (B029) Knockdown of MT1-MMP is sufficient to inhibit VHL negative renal cell carcinoma tumor growth, Matthew P. Vincenti; Ralph C. Nichols; R. Brooks Robey; Roy Fava; Brenda L. Petrella;
  • (B030) The role of NEMO in renal cell cancer ? towards a novel HIFα activation mechanism, Anna M. Nowicka1; Mathias Heikenwaelder2; Holger Moch1; Peter Schraml1;
  • (B031) The 5-Hydroxy Tetraindole (SK228) up-regulates miR-200 and leads to the reversal of EMT in breast cancer cells, Chie-Hong Wang1; Wen-Chun Hung2; Wen-Shan Li1;
  • (B032) Expression of protein kinase-η completely suppresses the expression and activity of matrix metalloproteinase-9 and decreases glioblastoma multiforme invasion, ISA M. HUSSAINI1; ZACHARY KOHUTEK2; BEATRIZ M. LOPES2;
  • (B033) Loss of RUNX3 increases osteopontin expression and promotes cell migration in gastric cancer, Yu-Peng Liu; Pei-Jung Lu;
  • (B034) Epstein-Barr virus latent membrane protein 2A promotes cell cycle progression through the downregulation of p27kip1 in a mouse model of Burkitt Lymphoma, Kamonwan Fish; Richard Longnecker;
  • (B035) Functional screening of prognostic gene libraries in a mouse model: an integrative approach for identification of stage-specific regulators of liver metastasis, Koji Okamoto1; Yuki Aihara2; Hirokazu Ohata1; Hitoshi Nakagama1;
  • (B036) Differential sensitivities to molecular target drugs in scirrhous gastric carcinoma cell lines, Hideki Yamaguchi1; Nachi Yoshida2; Miho Takanashi2; Kazuyoshi Yanagihara1; Ryuichi Sakai1;
  • (B037) Enhancer of Zeste Homolog 2 (EZH2) promotes progression of cholangiocarcinoma by regulating cell cycle and apoptosis, shigeki nakagawa; Sakamoto Yasuo; Hayashi Hiromitsu; Watanabe Masayuki; Beppu Toru; Baba Hideo;
  • (B038) Peroxiredoxins are Overexpressed in MCF-7 Breast Cancer Cells and Regulated by Proliferation and Oxidative Stress, Kekoa Taparra; Lauren Tehan; Shelley A. Phelan;
  • (B039) Exploring metastasis-related genes in spontaneous metastatic mouse model using human oral cancer cell line, Tomoki Muramatsu1; Ken-ichi Kozaki1; Imoto Seiya2; Rui Yamaguchi2; Satoru Miyano2; Johji Inazawa1;
  • (B040) The role of TFG-TEC fusion gene in human extraskeletal myxoid chondrosarcomas, Bobae Lim; Ah-young Kim; JeeHyun Choi; Jungho Kim;
  • (B041) Role of ADAM9 in lung cancer brain metastases, Yuh-Pyng Sher1; Chen-Yuan Lin1; Cheng-Chung Huang1; Guan-Chin Tseng2; Liang-Chuan Lai3;
  • (B042) Clinical significance of inactivated hippo-pathway as a prognostic biomarker in hepatocellular carcinoma, Hiromitsu Hayashi; Hideyuki Kuroki; Naomi Yokoyama; Shigeki Nakagawa; Katsunori Imai; Hidetoshi Nitta; Daisuke Hashimoto; Yoshiaki Ikuta; Akira Chikamoto; Toru Beppu; Hideo Baba;
  • (B043) Bit-1 promotes cell survival and correlates with clinical features predicting poor prognosis in Neuroblastoma, Mayumi Jijiwa1; Dirk Geerts2; Genevieve S. Griffiths3; Michelle L. Matter4;
  • (B044) Gelfoam histoculture of cancer cells enables their in vivo-like cell cycle behavior, Shuya Yano; Sumiyuki Mii; Yasunori Tome; Yukihiko Hiroshima; Fuminari Uehara; Shinji Miwa; Robert M. Hoffman;
  • (B045) Invasive cancer cells are mostly in the G0/G1 phase of the cell cycle, Shuya Yano; Sumiyuki Mii; Yasunori Tome; Yukihiko Hiroshima; Fuminari Uehara; Shinji Miwa; Robert M. Hoffman;
  • (B046) GCF2/LRRFIP1 promotes cancer invasion and metastasis through integrin-dependent RhoA activation, Hideo Ohtsuka; Daisuke Douchi; Kyouhei Ariake; Fuyuhiko Motoi; Koji Fukase; Yu Katayose; Hiroshi Yoshida; Takanori Morikawa; Takaho Okada; Kei Nakagawa; Hiroki Hayashi; Michiaki Unno;
  • (B047) EZH2-medaited epigenetic alteration may be associated with malignant behavior in IPMN by accelerating cell proliferation via a downregulation of p27KIP1, Hideyuki Kuroki; Hayashi Hiromitsu; Nakagawa Shigeki; Chikamoto Akira; Beppu Toru; Baba Hideo;
  • (B048) Oncogenic Ras-ERK signaling requires activation of CDCP1 pathway for promotion of tumor metastasis, Ryuichi Sakai; Tohru Kiyono; Takamasa Uekita;
  • (B049) C4.4A expression is associated with a poor prognosis of esophageal squamous cell carcinoma, Masahisa Ohtsuka; Hirofumi Yamamoto; Mamoru Uemura; Naotsugu Haraguchi; Junichi Nishimura; Taishi Hata; Ichiro Takemasa; Tsunekazu Mizushima; Yuichiro Doki; Masaki Mori;
  • (B050) Aberrant MUC1 and HER2 expression is associated with invasive phenotype of intraductal papillary mucinous neoplasm of pancreas (IPMN), Kenjiro Kimura; Ryosuke Amano; Akihiro Murata; Yoshihiro Okita; Hisashi Nagahara; Eiji Noda; Kubo Naoshi; Hiroaki Tanaka; Kazuya Muguruma; Kazuya Muguruma; Hiroshi Otani; Masaichi Ohira; Kosei Hirakawa;
  • (B051) The biomarker LCN2/NGAL regulates multiple tumor-associated genes and mechanisms in prostate cancer cells, Allon Hazan1; Joanne Selway2; Sandeep K. Nadendla1; Kenneth Langlands2; Luis Beltran3; Mike Philpott1; Graham W. Neill1;
  • (B052) Growth factor receptor signaling controls breast cancer stem cells and their niche, Noriko Gotoh1; Yukino Machida1; Kunihicko Hinohara1; Masaki Mori1; Toshihisa Ogawa2;
  • (B053) Pla2g16 phospholipase contributes to gain-of-function of mutant p53, Shunbin Xiong1; Houlin Tu1; Vinod Pant1; Young-Ah Suh1; Yun Zhang1; Qin Li1; Ana C. Elizondo-Fraire1; Peirong Yang1; Zhenlin Ju1; Amirali Hamir1; Lawrence A. Donehower2; Guillermina Lozano1;
  • (B054) Identification of CDCP1 as a HIF-2α target gene involved in the regulation of cancer cell migration and metastasis, Brooke M. Emerling1; Cyril H. Benes1; Eric Bell2; George Poulogiannis1; Kevin Courtney3; Hui Lui1; Rayman Choo-Wing1; Gary Bellinger1; Stephen P. Soltoff1; Lewis C. Cantley1;
  • (B055) Tumor-associated Lymphocytes Attenuate Tumor Immunity to Promote Progression of Serous Endometrial Cancer via STAT1 pathway, Budiman Kharma; Tsukasa Baba; Masaki Mandai; Hyun Sook Kang; Kaoru Abiko; Yumiko Yoshioka; Junzo Hamanishi; Ken Yamaguchi; Ikuo Konishi;
  • (B056) Irradiation alters the invasive potential of PANC-1 cell line thorough NO and NOS-PI3K-AKT pathway activities in addition to the SerP activity, Mayumi Fujita; Kaori Imadome; Yoshimi Shoji; Takashi Imai;
  • (B057) Epoxyeicosanoid regulation of tumor lymphangiogenesis, Karolina Serhan1; Dayna K. Mudge1; Diane R. Bielenberg1; Emily R. Greene1; Sung Hee Hwang2; Bruce D. Hammock2; Mark W. Kieran3; Dipak Panigrahy1;
  • (B058) Cancer immune-escalation process and the role of inflammatory tumor microenvironment for promoting metastasis, Yoshihiro Hayakawa;
  • (B059) Development of the specific peptide substrate for ADAM28, Toshifumi Akizawa1; Satsuki Mochizuki2; Yasunori Okada2;
  • (B060) NELL2 gene, a new transcriptional target of E2F1, Sun-Hee Leem1; Dong-Hee Kim1; Yun-Gil Roh1; In-Sun Chu2;
  • (B061) Roles of ezrin in tongue cancer progression, Shota Saito1; Hiroto Yamamoto1; Kin-ichi Mukaisho1; Sho Sato1; Takanori Hattori1; Gaku Yamamoto2; Hiroyuki Sugihara1;
  • (B062) The miR-1-Notch3-Asef pathway is important for colorectal tumor cell migration, Shiori Furukawa1; Yoshihiro Kwasaki1; Masaya Hiyoshi2; Kitayama Joji2; Akiyama Tetsu1;
  • (B063) Expression profile of SOX9 during progression of intraductal papillary mucinous neoplasmas of the pancreas, Fanbin Meng; Kyoichi Takaori; Tatsuo Ito; Toshihiko Masui; Michiya Kawaguchi; Shinji Uemoto;
  • (B064) The role of Wnt signaling pathway in the migration of oral squamous cell carcinoma cells, Atsuko Niki-Yonekawa; Soichi Iwai; Yoshihiro Morita; Yoshiaki Yura;
  • (B065) Tris(1-pentyl-1H-indol-3-yl)methylium chloride induces cytotoxicity in melanoma cell lines in vitro through autophagy, Oxana Ryabaya1; Elyco Solomko1; Evgenia Stepanova1; Sergey Lavrenov2;
  • (B066) Estrogen receptor β isoform 5 interacts with Bcl2L12 to enhance the apoptosis triggered by chemotherapeutic agents in breast cancer, Ming-tsung Lee; Pheruza Tarapore; Yuet-kin Leung; Hung-ming Lam; Shuk-mei Ho;
  • (B067) VEGF-targeting drug-screening identified a novel compound that can suppress tumor growth, invasion and angiogenesis in non-small-cell lung cancer, Chi-Chung Wang1; Yi-Hua Lai2; Yu-Lin Ai2; Huei-Wen Chen3; Hsuan-Yu Chen4; Jeremy J.W. Chen2;
  • (B068) YB-1-mediated hypoxic response regulation: A novel mechanism contributing to sarcoma metastasis, Amal EL-Naggar1; Cristina Tognon2; Hongwei Cheng2; Syam Prakash2; Wang Yuzhuo2; Poul Sorensen1;
  • (B069) Induction of apoptosis in the TNBC cells through dsDNA decoy-mediated functional impairment of SLUG activity, Mukul K. Mittal; Gautam Chaudhuri;
  • (B070) YB-1 contributes to sarcoma metastasis via translational activation of HIF1α, Amal EL-Naggar1; Chansey Veinotte2; Cristina Tognon1; Hongwei Cheng3; Syam Somasekharan1; Yuzhuo Wang3; Jason Berman2; Poul Sorensen1;
  • (B071) Rosehip Extracts Prevent Triple Negative Breast Cancer Cell Migration and Proliferation by Regulating the Phosphorylation of P70s6 Kinase, Tonisa L. Coburn; Ademola I. Shofoluwe; Patrick M. Martin, Sr.;
  • (B072) MicroRNA deregulation associated with metastasis and recurrence of non-small cell lung cancer, Katey SS Enfield; Varune R. Ramnarine; David A. Rowbotham; Stephen Lam; Wan L. Lam;
  • (B073) Interaction of TNF-alpha and BCCIP alpha Gene Polymorphisms in Increased Prostate Cancer Risk, Radhika Gade Andavolu1; James MacMurray2; Murthy VS Andavolu1; Jean-Luc Cardenas1; Jaski S. Bir1; Narayan Vishnu Reddy1; Shinger Shu1; Svetlana Rubakovic1;
  • (B074) Inhibitory Effects of Anthocyanins from the Fruit of Vitis coignetiae Pulliat on EMT through Dual Suppression of Akt and EGFR in A549 Human Lung Cancer Cells, Won Sup Lee; Jing Nan Lu; Yun Jeong Won;
  • (B075) Tracing the influence of the tumor microenvironment on clonal selection using intravital microscopy, Jae-Hyun Park; Miriam R. Fein; Mikala Egeblad;
  • (B076) Changes in the PNC components? gene expression and PNC prevalence as a prognostic value in prostate cancer, Marzena A. Lewandowska1; W. Jozwicki1; J. Rytlewska2; Sui Huang3;
  • (B077) ZNF322A overexpression leads to transcriptional deregulation of p53 and cyclin D1 in lung cancer, Jayu Jen; Sheng-You Liao; Fang-Yi Lo; Hsiang-Ting Chen; Yi-Ching Wang;

    EPIGENETICS AND CANCER CELL STATES

  • (B078) ATRT brain tumors: A quiet genome with an active methylome, Ratan D. Bhardwaj1; C Hampton2; Winnie Liang2; Waibhav Tembe2; Nhan Tran2; Anat Erdreich-Epstein3; Michael Berens2; Bodour Sahlia2;
  • (B079) EZH2 Generates a Methyl Degron that Is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex, Hyunkyung Kim; Sung Hee Baek;
  • (B080) Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK) inhibits stemness of CD133-positive gastric cancer cells by suppressing ADAM-mediated Notch1 Activation, Hong Kun-Jing1; Hung Wen-Chun2;
  • (B081) Clinical and prognostic significance of LINE-1 methylation level in liver metastases from colorectal cancer, Yoshifumi Baba; Masayuki Watanabe; Asuka Murata; Hironobu Shigaki; Shiro Iwagami; Yasuo Sakamoto; Yuji Miyamoto; Toru Beppu; Hideo Baba;
  • (B082) Hypomethylation of the IGF2 DMR0 in Esophageal Squamous Cell Carcinoma, Detected by Bisulfite Pyrosequencing, is Associated with Poor Prognosis, Asuka Murata; Yoshihumi Baba; Masayuki Watanaabe; Hironobu Shigaki; Keisuke Miyake; Nobuyuki Ozaki; Takatsugu Ishimoto; Masaaki Iwatsuki; Shiro Iwagami; Yasuo Sakamoto; Yuji Miyamoto; Naoya Yoshida; Hideo Baba;
  • (B083) Identification of novel methylation-silenced genes which are associated with malignant transformation from oral premalignant legions to oral cancers, Masanobu Abe1; Satoshi Yamashita2; Yoshiyuki Mori1; Takahiro Abe1; Hideto Saijo1; Yoko Kawase-Koga1; Hideyuki Suenaga1; Toshikazu Ushijima2; Tsuyoshi Takato1;
  • (B084) H3K9 histone demetylase, KDM4B, constitute a key component of the estrogen signaling pathway in vivo and in vitro, Kayoko Saso; Masahito Kawazu; Kit I. Tong; Hitoshi Okada;
  • (B085) Transcriptional repression mediated by Histone Deacetylase Inhibitors, Keith Bonham1; Erika Beaton-Brown2;
  • (B086) Study about induction of aberrant DNA methylation after hepatitis viral infection using human hepatocyte chimeric mouse, Keiko Shinjo1; Yasuyuki Okamoto1; Yasuhiro Shimizu2; Tsuyoshi Sano2; Kenji Yamao2; Jean-Pierre Issa3; Yutaka Kondo1;
  • (B087) Comprehensive DNA methylation and extensive mutation analyses reveal an association between the CpG island methylator phenotype and oncogenic mutations in gastric cancers, Jeong Goo Kim1; Hideyuki Takeshima1; Tohru Niwa1; Hitoshi Katai2; Cho Hyun Park3; Toshikazu Ushijima1;
  • (B088) Brg1 and EGFR mutations predict synergy of EZH2 inhibition and chemotherapy in lung cancer, Christine Marie Fillmore; Carla Faith Kim;
  • (B089) Suppressed NDRG2 expression correlates with poor prognosis in pancreatic cancer, and the suppression mechanisms are distinct from that of colorectal and gastric cancers, Yasuhiko Mizuguchi1; Akihiro Yamamura1; Koh Miura1; Hideaki Karasawa1; Kazuhiro Morishita2; Yuriko Saiki1; Shinichi Fukushige1; Fuyuhiko Motoi1; Shinichi Egawa1; Chikashi Shibata1; Michiaki Unno1; Akira Horii1;
  • (B090) DNA methylation profiles at precancerous stages associated with recurrence of lung adenocarcinoma, Takashi Sato1; Eri Arai1; Takashi Kohno2; Koji Tsuta3; Shun-ichi Watanabe4; Kenzo Soejima5; Tomoko Betsuyaku5; Yae Kanai1;
  • (B091) Leukemia-associated MLL-AF10 maintains an active state of chromatin on its target genes by recruiting Tip60, Kazutsune Yamagata; Mika Shino; Aikawa Yukiko; Issay Kitabayashi;
  • (B092) The role of histone citrullination through p53/PADI4 network in carcinogenesis, Chizu Tanikawa; Yusuke Nakamura; Koichi Matsuda;
  • (B093) The role of histone modification in the construction of superficial type squamous cell carcinoma of the pharynx, Satoshi Fujii1; Tomonori Yano2; Keiko Minashi2; Atsushi Ochiai1; Hiroyasu Esumi3; Ryuichi Hayashi4;
  • (B094) Differential roles of forkhead transcription factors FOXA1 and FOXP1 for estrogen receptor signaling in breast cancer, Satoshi Inoue1; Kazuhiro Ikeda2; Kuniko Horie2;
  • (B095) Role of JMJD1A in hypoxia-induced EMT and therapeutic resistance in colorectal cancer, Susumu Miyazaki; Hirofumi Yamamoto; Masayuki Hiraki; Mamoru Uemura; Naotsugu Haraguchi; Naotsugu Haraguchi; Junichi Nishimura; Taishi Hata; Ichiro Takemasa; Tsunekazu Mizushima; Yuichiro Doki; Masaki Mori;
  • (B096) Critical pathways for maintenance of stem cells in acute myeloid leukemia, Yukiko Aikawa; Mika Shino; Haruko Shima; Emi Takamatsu; Issay Kitabayashi;
  • (B097) Single-CpG-resolution methylome analysis identifies clinicopathologically aggressive CpG island methylator phenotype clear cell renal cell carcinomas, Eri Arai1; Taisuke Mori1; Masahiro Gotoh1; Tohru Nakagawa2; Hiroyuki Fujimoto2; Yae Kanai1;
  • (B098) FACTs role as a marker and target in cancer, Henry Garcia; Jeffrey Miecznikowski; Mairead Commane; Geraldine Paszkiewicz; Carl Morrison; Katerina Gurova;
  • (B099) Associations of MutL homolog 1 (MLH1) CpG island shore methylation with SNP variants and tissue type in peripheral blood and tumor DNA in colorectal cancer patients, Andrea J. Savio1; Mathieu Lemire2; Miralem Mrkonjic1; Steven Gallinger1; Brent W. Zanke3; Thomas J. Hudson2; Bharati Bapat1;
  • (B100) Mutations in the H3K36 methyltransferase SETD2 link chromatin defects with aberrant RNA processing in human clear cell renal cell carcinoma, Kathryn E. Hacker1; Jeremy M. Simon1; Darshan Singh1; A. Rose Brannon2; Joel S. Parker1; Matthew Weiser1; Thai H. Ho3; Pei-Fen Kuan1; Eric Jonasch3; Terrence S. Furey1; Jan F. Prins1; Jason D. Lieb1; W. Kimryn Rathmell1; Ian J. Davis1;
  • (B101) Epigenomic alterations in normal respiratory epithelia and lung cancer cells mediated by cigarette smoke: In-vitro modeling and translational implications, David S. Schrump1; Sichuan Xi1; Mary Zhang1; Xinmin Li2; Fang Liu1; J Keith Killian1; Julie A. Hong1; Mahadev Rao1;
  • (B102) TMPRSS2-ERG gene fusions in prostate cancer: Genome-wide localization and functional consequences, Ram-Shankar Mani1; Matthew Iyer1; Qi Cao1; J. Chad Brenner1; Lei Wang1; Aparna Ghosh1; Yi-Mi Wu1; Xuhong Cao1; Meng Zhao2; Robert J. Lonigro1; Zhaohui Qin2; Scott A. Tomlins1; Nallasivam Palanisamy1; Sooryanarayana Varambally1; Arul M. Chinnaiyan1;

    DNA DAMAGE RESPONSE

  • (B103) Differential regulation of CAK anchoring to core TFIIH by XPB and XPD helicases during nucleotide excision repair, Qianzheng Zhu; Gulzar Wani; Nidhi Sharma; Altaf A. Wani;
  • (B104) Identification of a novel mechanism for p53-mediated apoptosis and microRNA metabolism in response to genotoxic stress, Naoe Taira1; Yoshio Miki2; Kiyotsugu Yoshida1;
  • (B105) Brca1 deficiency activates Akt1 oncogenic kinase in the homologous recombination pathway, Qin Yang; Yunhe Jia; Wilbur Song; Jinchun Yan; Fan Zhang;
  • (B106) USP44 is a multifunctional tumor suppressor required for genomic integrity, Ying Zhang1; Oded Foreman2; Dennis Wigle1; Farhad Kosari1; George Vasmatzis1; Jeffrey Salisbury1; Jan van Deursen1; Paul Galardy1;
  • (B107) The comprehensive study for the target genes of the Serine 46 phosphorylation of the p53, Nurmaa Dashzeveg1; Naoe Taira2; Yoshio Miki1; Kiyotsugu Yoshida2;
  • (B108) CHK1 inhibition is effective in enhancing Cisplatin response in ovarian cancer cell lines with DNA Damage Response defects, Petranel T. Ferrao; Teresa Ward; Lisa Grass; Patricia E. Bukczynska; Jason Ellul; Karen Sheppard; Dariush Etemadmoghadam; Richard B. Pearson; Grant A. McArthur;
  • (B109) Functional involvement of tankyrase in DNA damage repair, Mika Kuroiwa1; Tomokazu Ohishi1; Yukiko Muramatsu1; Shun-ichiro Iemura2; Tohru Natsume2; Hiroyuki Seimiya1;
  • (B110) Shifting doxorubicin activity from topoisomerase-II poison to adduct formation reduces cardiotoxicity while maintaining anticancer efficacy, David M. Rayner1; Ada Rephaeli2; Abraham Nudelman3; Salvatore Pepe4; Don R. Phillips1; Suzi M. Cutts1;
  • (B111) Targeting glioma stem cells by G-quadruplex ligands, Hiroyuki Seimiya1; Sachiko Okabe1; Yukiko Muramatsu1; Takahiro Nakamura2; Keisuke Iida2; Kazuo Nagasawa2; Takao Yamori3; Ichiro Nakano4; Kazuo Shin-ya5;
  • (B112) Functional characterization of polymorphic alleles in the TP53 gene, Marc R. Birtwistle1; Zuzana Berrong1; Keely Duff1; Emily Cloessner1; Josephine Tidwell1; Megan Clendenning1; brent wilkerson1; brent wilkerson1; Christopher Farrell1; Ji Hao2; Michael Shtutman2; Kim Creek2; Carolyn E. Banister2; Phillip J. Buckhaults1;
  • (B113) The effect of histone deacetylase inhibition on the DNA damage response, K. Ted Thurn; Scott Thomas; Paromita Raha; Stephanie Chen; Pamela Munster;
  • (B114) The PIDDosome in the DNA damage response and cancer therapy, Kiyohiro Ando; Jennifer L. Kernan; Peter H. Liu; Samuel Sidi;