American Association for Cancer Research

Poster Session D

Poster Session D
Monday, February 25
4:30 p.m.-6:30 p.m.

(In board assignment order, subject to change)


    SIGNALING AND SYSTEMS BIOLOGY

  • (D001) The Mu Opioid Receptor is a Novel Regulator of Human Lung Cancer Epithelial Mesenchymal Transition (EMT): Role of Src, Gab-1, PI3K, Akt and STAT3 , Frances E. Lennon; Tamara Mirzapoiazova; Bolot Mambetsariev; Valeriy A. Poroyko; Ravi Saigia; Jonathan Moss; Patrick A. Singleton;
  • (D003) Discovery of cancer drug targets in vitro and in vivo using pooled shRNA libraries, Donato Tedesco1; Kyle Bonneau1; Mikhail Makhanov1; Costas Gus Frangou2; Alex Chenchik1;
  • (D004) RNAi genetic screening for drug target discovery, Andrei Komarov1; Elena Komarova2; Karim Hyder1; Lilya Novototzkaja2; Michael Yeluashvili1; Dmitry Suchkov1; Kyle Bonneau1; Donato Tedesco1; Costas Gus Frangou2; Paul Diehl1; Debbie Deng1; Pavel Komarov2; Andrei Gudkov2; Alex Chenchik1;
  • (D005) Quantitative phosphoproteomics identifies activation of the RET and IGF-1R/IR signaling pathways in N-myc amplified neuroblastoma, Michael P. Holloway1; Bradley D. Denardo1; Qinqin Ji1; Marcus B. Valentine2; Jill Lahti2; Arthur Salomon1; Rachel A. Altura1;
  • (D006) Inner mitochondrial space-stress activates distinct mitochondrial UPRs, Luena Papa; Doris Germain;
  • (D007) APPL2-mediated resistance of glioma cells to death upon c-Met inhibition., Beata Pyrzynska; Marta Miaczynska;
  • (D008) Functional analysis of ALDH1 and TGF-β in pancreatic cancer-initiating cells., Yukari Hoshino; Shogo Ehata; Yoko Katsuno; Kohei Miyazono;
  • (D009) Constructing a 'similarity space' from complex genomics data to aid personalized treatment decisions for childhood cancer patients., Daniel R. Catchpoole1; Nicholas Ho1; Guy Nelmes1; Patricio J. Alzamora2; Ahmad AlOqaily3; Quang Vinh Nguyen2; David Skillicorn4; Paul Kennedy3;
  • (D010) HOXB9 gene's sequence specific factors as promotes of breast cancer metastasis., Aisulu ZHUSSUPOVA; Tetsu HAYASHIDA; Maiko TAKAHASHI; Hiromitsu JINNO; Yuko KITAGAWA;
  • (D011) Correlative Biology Studies of Childhood Leukemias by Microwave & Magnetic (M2) Proteomics, Xiaolin Zhang1; Rekha Raghunathan1; Swetha Mahesula1; Venkat Kotagiri1; Jose AT Ruiz2; Karen Rabin3; Terzah Horton3; Jonathan AL Gelfond4; William E. Haskins1;
  • (D012) Unraveling the cross-talk between heme-oxygenase 1 (HO-1), STAT3 and NFKB in prostate cancer, Geraldine Gueron1; Belen Elguero1; Jimena Giudice2; Martin Andres Toscani1; Federico Coluccio-Leskow1; Roberto Meiss3; Adriana De Siervi1; Nora Navone4; Elba Vazquez1;
  • (D013) Glucocorticoid Represses Hypoxia-induced COX-2 and Hypoxia-Inducible-Factor-1α Expression through Induction of Glucocorticoid-Induced Leucine Zipper, Wonchung Lim; YoungJoo Lee;
  • (D014) BMP4 suppresses tumorigenic activity of glioma-initiating cells through loss of stemness properties, Akiyoshi Komuro1; Hiroaki Ikushima1; Satoshi Sakai1; Yasushi Ino2; Tomoki Todo2; Nobuhito Saito3; Tetsuro Watabe1; Daizo Koinuma1; Kohei Miyazono1;
  • (D015) Clinicopathological and molecular correlates of HER2 expression and PI3K-Akt pathway alterations in gastric cancer, Yasutaka Sukawa; Hiroyuki Yamamoto; Miki Ito; Hiroaki Kunimoto; Katsuhiko Nosho; Yasushi Adachi; Hiromu Suzuki; Takumi Hasegawa; Koichi Hirata; Yasuhisa Shinomura;
  • (D017) Gene combination regulated in stem cells and gastric cancer cells, Shihori Tanabe1; Kazuhiko Aoyagi2; Hiroshi Yokozaki3; Hiroki Sasaki2;
  • (D018) Discovery of gene signature via pathways and meta analysis in lung adenocarcnoma, Chi-Sheng Chang1; Ya-Hsuan Chang1; Yi-Chiung Hsu1; Sung-Liang Yu2; Jeremy Jian-Wei Chen3; Huei-Wen Chen2; Ang Yuan4; Szu-Hua Pan2; Hsuan-Yu Chen1;
  • (D019) Molecular mechanisms of TGF-beta signal modification by TTF1, Kazunobu Isogaya; Daizo Koinuma; Shuichi Tsutsumi; Hiryoyuki Aburatani; Kohei Miyazono;
  • (D020) p53 inactivation by anaplastic lymphoma kinase through the direct tyrosine phosphorylation of p53, Masato Enari;
  • (D021) Preparation of the K63-linked polyubiquitin-specific affinity column packed with the resin conjugated with the Zinc Finger peptide derived from TAK1 binding protein 2, Aya Kojima1; Toshifumi Akizawa2; Jun-ichiro Inoue1;
  • (D022) Genome-wide identification of Smad2/3 binding regions during TGF-β-induced epithelial to mesenchymal transition in NMuMG cells, Tomohiro Ogami1; Daizo Koinuma1; Shuichi Tsutsumi2; Kana Horiguchi1; Hiroyuki Aburatani2; Kohei Miyazono1;
  • (D023) Pathway-based phosphoprotein profiling by high-density protein array, Mari Masuda; Kazufumi Honda; Tesshi Yamada;
  • (D024) Roles of THG-1/Tsc22D4 in cell proliferation, differentiation and tumorigenesis, Hiroyuki Suzuki; Yukari Okita; Mitsuyasu Kato;
  • (D025) A critical role of the SUMOylation pathway in KRAS-driven transformation, Bing Yu1; Steve Swatkoski2; Alesia Holly1; Liam C. Lee1; Valentin Giroux1; Chih-Shia Lee1; Chad Creighton3; William Douglas Figg1; Marjan Gucek2; Ji Luo1;
  • (D026) The role of TNFα and NFκB in the adaptive response, Richard C. Miller; Jeffrey S. Murley; Kenneth L. Baker; Ralph R. Weichselbaum; David J. Grdina;
  • (D028) Three-dimensional nuclear telomere organization in advanced non-small cell lung cancer patients and its correlation with epidermal growth factor receptor mutational status, Patrapim Sunpaweravong1; Phatcharaporn Thongwatchara1; Sabine Mai2;
  • (D029) Perturbation cell biology: Network models of drug response in cancer cells, Anil Korkut; Weiqing Wang; Evan Molinelli; Arman Aksoy; Martin Miller; Kaushik Poorvi; Chris Sander;
  • (D030) Regulation of insulin-like growth factor binding protein-3 by Akt in human non-small cell lung cancer cells , Quanri Jin1; Hye-Young Min2; Young Mi Whang1; Yeul Hong Kim3; Ho-Young Lee2;

    CANCER PREVENTION

  • (D031) MicroRNA-93 regulates NRF2 expression and is associated with breast carcinogenesis, Hari K. Bhat; Bhupendra Singh;
  • (D032) A role of Gronwell seed in preventive effects of in vitro and in vivo carcinogenesis test, Harukuni Tokuda; Takanari Arai; Yuko Takimoto; Jeffrey Strong; Andrew Schneider; Nobutaka Suzuki;
  • (D033) Potent anti-cancer effect of crocin against hepatocellular carcinoma: A preclinical study, Amr Amin1; Regine Scneider-Stock2; Sayel Daoud3;
  • (D034) Natural product MDM2 inhibitors for cancer prevention and therapy, Ruiwen Zhang;
  • (D035) Alcohol drinking plus areca chewing and smoking is associated with poor prognosis of esophageal squamous cell carcinoma, I-Chen Wu; Ming-Tsang Wu;
  • (D036) The effect of tumor suppression of C6 glioma cells by EGFR/VEGF inhibitor, ZD6474, Atsushi Kambe1; Brian Wasita2; Masamichi Kurosaki1; Takashi Watanabe1;
  • (D037) Garcinol induced G1 cell cycle through p38-MAPK inhibition in H1299 human non-small cell lung carcinoma cells, Sheng-Yung Yu; Meng-Shih Weng;
  • (D038) Cancer prevention agents induce cellular senescence in mammary premalignant lesions and tumors , Anne Shilkaitis; Albert Green; Laura Bratescu; Tohru Yamada; Konstantin Christov;
  • (D039) Polymorphisms in DNA repair genes, recreational physical activity and breast cancer risk, Lauren E. McCullough1; Regina M. Santella2; Rebecca Cleveland1; Robert Millikan1; Andrew Olshan1; Kari North1; Patrick Bradshaw1; Sybil Eng2; Mary Beth Terry2; Jing Shen2; Katherine Crew2; Pavel Rossner3; Susan Teitelbaum4; Alfred Neugut2; Marilie Gammon1;
  • (D040) Corosolic acid inhibits human ovarian cancer cell proliferation, Kiyomi Takaishi1; Fumiko Ito2; Junko Nakao1; Yukio Fujiwara3; Yoshihiro Komohara3; Hironori Tashiro2; Hidetaka Katabuchi2;
  • (D041) Development of mice model for inquiry into therapeutic targets: an anticancer effect of dienogest on endometrial neoplasm, Fumitaka Saito; Hironori Tashiro; Ritsuo Honda; Takashi Ohba; Hidetaka Katabuchi;
  • (D042) The Japan Multi-institutional Collaborative Cohort (J-MICC) Study: its design and progress, Kenji Wakai1; Haruo Mikami2; Kiyonori Kuriki3; Sadao Suzuki4; Yoshikuni Kita5; Yoshiyuki Watanabe6; Kokichi Arisawa7; Keizo Ohnaka8; Norihiro Furusho8; Keitaro Tanaka9; Toshiro Takezaki10; Michiaki Kubo11; Nobuyuki Hamajima1; Hideo Tanaka12; J-MICC Study Group13;
  • (D044) Cytosponge?: A tool for screening and risk stratification of Barrett?s esophagus, Caryn S. Ross-Innes; Sibu Varghese; Pierre Lao-Sirieix; Rebecca C. Fitzgerald;
  • (D045) Role of hypertriglyceridemia in intestinal carcinogenesis in association with lipoprotein receptor , Michihiro Mutoh; Gen Fujii; Masami Komiya; Mami Takahashi; Hitoshi Nakagama;
  • (D046) Obesity-induced activation of the Androgen Receptor in Human Prostate Cancer Cells, Ramona S. Price; Faryal Siddiqui; Shruti Apte; Linda deGraffenried;
  • (D047) Turmerone abolishing cancer stem cell in esophageal cancer , Yan Li; Prejesh Philips; Li Suping; Martin C. Robert;
  • (D048) Anti-inflammatory effects of black raspberries in ulcerative colitis are associated with protective modulation of pro- and anti-inflammatory eicosanoids, Chieh-Ti Kuo1; Jibran Siddiqui1; Jo-Hsin Chen1; Yi-Wen Huang1; Guang-Yu Yang2; Gary Stoner1; Li-Shu Wang1;
  • (D049) Epigenetic regulation of tumor suppressor genes in esophageal cancer by berries, Yi-Wen Huang; Chieh-Ti Kuo; Dan Peiffer; Noah P. Zimmerman; Li-Shu Wang; Gary D. Stoner;
  • (D050) Intracellular metformin concentrations in non-small cell lung cancer (NSCLC) cell lines quantitated by a novel liquid chromatography mass spectrometry assay, Jennifer R. King; Amanda Marie James; Daniel L. Ross;
  • (D051) Metabolomic analysis for discovery of biomarkers of dietary supplementation with bean extracts or resveratrol to prevent colon cancer, Matthew R. Young1; Gerd Bobe2; Shakir Saud1; Terry Hartman3; Christopher Dextras1; Young Kim4; Nancy H. Colburn1; Ed Karoly5; Elizabeth Kensicki5; Brant Sampey5; Chris Bernard5;

    TARGETED THERAPIES AND RESISTANCE

  • (D052) Comparison of Epidermal Growth Factor Receptor Mutation Tests in Patients with Recurred Non-small Cell Lung Cancer after Surgery , Young-Chul Kim; Kyu-Sik Kim; In-Jae Oh; Kook-Joo Na; Sung-Ja Ahn; Hyunwook Kang; Yoo-Duk Choi; Chan-Woo Park;
  • (D053) Preclinical development of a Highly Active Anti-Tumor Therapy (HAATT) in pancreatic cancer, N.V Rajeshkumar1; Shinichi Yabuuchi1; Chirag Patel1; Shweta G. Pai1; Dung T. Le1; Daniel D. Von Hoff2; Chi V. Dang3; Anirban Maitra1; Jonathan D. Powell1;
  • (D054) Activation of autophagy inhibits B-cell lymphoblastic leukemia by degrading DNA and RNA polymerases, Na Yuan1; Suping Zhang1; Yuna Niu1; Aihong Zhang1; Yan Cao1; Zhijian Wang1; Nan Xi1; Suning Chen2; Wenli Zhao3; Xueguang Zhang4; Jianrong Wang1;
  • (D055) Therapeutic potential of EGFR juxtamembrane domain derived peptide in breast cancer, Hsin-Yuan Su; Matthew Hart; Derrick Broka; Joyce Schroeder;
  • (D056) Inhibition of microRNA-27a/b as a novel therapeutic approach to treat mantle cell lymphoma, Richard Phipps; Collynn Woeller; Steven Bernstein;
  • (D057) 19-Substituted benzoquinone ansamycin Hsp90 inhibitors. Biological activity and decreased off-target toxicity, David Ross1; Chuan-Hsin Chang1; Russell R.A. Kitson2; Rui Xiong1; David Siegel1; Christopher J. Moody2;
  • (D058) Tumor targeting Salmonella typhimurium A1-R kills quiescent cancer cells in vitro and in vivo, Shuya Yano; Yong Zhang; Fuminari Uehara; Yukihiko Hiroshima; Shinji Miwa; Robert M. Hoffman; Ming Zhao;
  • (D059) Suppression of FOXM1 sensitizes human cancer cells to cell death induced by DNA-damage and oxidative stress, Marianna Halasi; Andrei Gartel;
  • (D060) Clinical application of EML4-ALK lung cancer oncogene, Manabu Soda1; Kengo Takeuchi2; Young Lim Choi3; Toshihide Ueno1; Yoshihiro Yamashita1; Hiroyuki Mano1;
  • (D061) AS70302 Circulating Tumor Cells and Other New Diagnostic Technologies6, MEK1/2 inhibitor, can bypass resistance to PLX4032 in human malignant melanoma cells, Seung-Mi Kim; Kyung-Ah Jung;
  • (D062) EGCG selectively induces autophagy-related cell death in VHL-intact RCC cells, Jui-An Lin1; Chia-Jung Hsiao2; Yu-Hua Wu2; Niann-Yiing Chou3; Yao-Ting Hsieh3; Chao-Wen Cheng2;
  • (D063) Development of a novel anti-cancer therapy targeting vasohibin-2, Takahiro Koyanagi1; Yasuhiro Suzuki1; Miho Kobayashi1; Hiroki Miyashita1; Yasushi Saga2; Mitsuaki Suzuki2; Yasufumi Sato1;
  • (D064) Development of SNIPER(ER) that induces estrogen receptor degradation followed by rapid cell death in breast cancer cells, Keiichiro Okuhira; Yosuke Demizu; Nobumichi Ohoka; Norihito Shibata; Takayuki Hattori; Tomoko Nishimaki-Mogami; Masaaki Kurihara; Haruhiro Okuda; Mikihiko Naito;
  • (D065) Gene profile in colorectal cancer in association with the response to adjuvant chemotherapy with S-1, Kohei Yamauchi; Toshio Kokuryo; Keisuke Uehara; Yukihiro Yokoyama; Masato Nagino;
  • (D066) SIRT2, a promising molecular target for therapy of glioblastoma, Kanae Echzien1; Kosuke Funato1; Yukiko Nasu-Nishimura1; Ryo Koyama-Nasu1; Tomoki Todo2; Nobuhito Saito2; Yasushi Ino2; Tetsu Akiyama1;
  • (D067) The AMPK activator AICAR inhibits proliferation in oral squamous cell carcinoma, Koroku Kato; Natsuyo Noguchi; Hiroko Kitahara; Kunio Yoshizawa; Shuichi Kawashiri;
  • (D068) HomeoboxB9 is a potential surrogate marker for bevacizumab in combination with chemotherapy in colorectal cancer., Tetsu Hayashida; Yoshinori Hoshino; Akira Hirata; Hirotoshi Hasegawa; Hiromitsu Jinno; Yuko Kitagawa;
  • (D069) Role for the telomere maintenance system in cancer stemness of glioma cells, Sachiko Okabe1; Ichiro Nakano2; Hiroyuki Seimiya1;
  • (D070) c-Myc contributes to 5-fluorouracil resistance by regulating the expression of ATP-binding cassette (ABC) transporters, Naruji Kugimiya1; Arata Nishimoto1; Toru Hosoyama1; Tadahiko Enoki1; Tao-Sheng Li2; Kimikazu Hamano1;
  • (D071) Suppression of E2F1 by lapatinib induces synergistic antitumor effect of capecitabine in HER2 positive breast cancer, Akiko Matsumoto; Tetsu Hayashida; Maiko Takahashi; Hiromitsu Jinno; Yuko Kitagawa;
  • (D072) Nucleophosmin blocks BAX mitochondrial translocation and activation to help cancer cells evade death stimuli, Sen-Yung Hsieh;
  • (D073) Combined inhibition of histone deacetylase and the estrogen receptor induces cytotoxicity in tamoxifen resistant cells by modulating AKT and mTOR mediated signaling., Paromita Raha; Scott Thomas; Kenneth Ted Thurn; Stephanie Chen; Pamela Munster;
  • (D074) Acquired resistance to ROS1 inhibition in non-small cell lung cancer, Kurtis D. Davies; David Astling; Anh T. Le; Sakshi Mahale; Aik-Choon Tan; Marileila Varella-Garcia; Robert C. Doebele;
  • (D075) Identification of small molecule inhibitors of splicing factor PTBP1 as potential therapeutic agents to treat ovarian cancer, William T. Beck; Ahmet Dirim Arslan; Tsui-Ting Ho; Neena Majumdar; Lamiaa El-Shennawy; Matthew Maggio; Xiaolong He;
  • (D076) Inhibition of Akt sensitizes endometrial cancer cells to progestin through the upregulation of Progesterone Receptor B dependent transcription., Irene I. Lee; J. Julie Kim;
  • (D077) RET fusion gene: translation to the therapy of lung adenocarcinoma, Takashi Kohno1; Hitoshi Ichikawa1; Koji Tsuta2; Tatsuji Mizukami1; Yoko Shimada1; Mamoru Kotoh1; Hiromi Sakamoto1; Katsuya Tsuchiraha3; Shun-ichi Watanabe2; Hiroshi Nokihara2; Koichi Goto3; Jun Yokota1; Teruhiko Yoshida1; Tatsuhiro Shibata1;
  • (D078) Vorinostat, a HDAC inhibitor, overcomes BIM deletion polymorphism-mediated EGFR-TKI resistance in EGFR mutant lung cancer., Seiji Yano; Takayuki Nakagawa; Tadaaki Yamada; Hiromichi Ebi; Shinji Takeuchi;
  • (D079) Jab1 plays an important role in drug resistance by stabilizing STAT3 and HIF-1 DNA-binding, Arata Nishimoto1; Naruji Kugimiya1; Toru Hosoyama1; Tadahiko Enoki1; Tao-sheng Li2; Kimikazu Hamano1;
  • (D080) The 5-aminolevulinic acid-mediated photodynamic therapy is effective for glioma spheroid cell with high expression of ABCG2, Takahiro Fujishiro; Yoshinaga Kajimoto; Shinichi Miyatake; Toshihiko Kuroiwa;
  • (D081) Possibility of combination therapy of molecular targeted drugs for gastrointestinal stromal tumor, Masahiro Yamamura; Toshihiro Hirai; Tsutomu Nohno; Makoto Okawaki; Katsuji Hironaka; Yoshiyuki Yamaguchi;
  • (D082) Enhanced tumor selectivity for tumor imaging and radionuclide therapy
    by using liposomes encapsulating unique radionuclide-ligand complexes
    , Izumi O. Umeda1; Yusuke Koike1; Sadaaki Kimura1; Yoshiki Kojima1; Kenjiro Higashi2; Kunikazu Moribe2; Keiji Yamamoto2; Hirofumi Fujii1;
  • (D083) Identification of IGF1R as a responsible gene and a therapeutic target for acquired and intrinsic resistance to PI3K inhibitors, Shingo Dan; Sho Isoyama; Yumiko Nishimura; Naoki Nakamura; Gensei Kajiwara; Naomi Tamaki; Mutsumi Okamura; Takao Yamori;
  • (D084) A HER3 antibody that blocks ligand-independent HER2-HER3 dimerization inhibits growth of HER2-dependent tumors and sensitizes to HER2 and PI3K inhibitors, Joan T. Garrett; Cammie R. Sutton; Carlos L. Arteaga;
  • (D085) Complexed drug resistance mechanisms in the arginine-auxotrophic malignant melanoma treated with arginine-degrading recombinant protein, peglated arginine deiminase ADI-PEG20. , Wen-bin Tsai1; Yan Long1; Medhi Wangpaichitr2; Lynn Feun3; Niramol Savaraj2; Macus Kuo1;
  • (D086) Inhibiting the Janus Activated Kinase (JAK) family in Renal Cell Carcinoma, Bhavani Krishnan; Baiely T. Sean; William Y. Kim;
  • (D087) A small molecule activator of protein phosphatase 2A for the treatment of human cancer, Neil S. Dhawan1; David Kastrinsky1; Sahar Mazhar2; Jaya Sangodkar1; Sudeh Izadmehr1; Eric Yuan2; Kim McClinch1; Caroline Farrington2; Agnes Stachnik1; Heather Melville1; Blake Smith1; Vickram Gidwani2; Analisa V. DiFeo2; Matthew Galsky1; Avi Mayan1; Yiannis Ioannou1; Michael Ohlmeyer1; Goutham Narla2;
  • (D088) Levels of PI4KB and PIP5K1A affect dependence of breast cancers on mutant PIK3CA, Cheryl Eifert;
  • (D089) Docosahexaenoic acid downregulates cancer cell metabolism and invasion in part by altering ErbB2-related cell adhesion, Keith D. Kikawa; Palvinder Bains; Dylan S. Raatz; Michael Mouradian; Ronald S. Pardini;
  • (D090) Exploring the molecular and cellular mechanisms that underlie the conversion of EGFR mutant lung adenocarcinomas to small cell lung cancer upon treatment with tyrosine kinase inhibitors, Mary Ann C. Melnick; Katerina Politi;
  • (D091) Akt pathway mediates Notch-regulated self-renewal in some glioblastoma stem cells, Mary Soules; Thant Zhu; Jason Heth; Karin Muraszko; Xing Fan;
  • (D092) Combination erlotinib and cisplatin causes synergistic cell death and decrease invasion in lung adenocarcinoma, Jasmine G. Lee; Reen Wu;
  • (D093) The Tumor Microenvironment as Co-Target: Blocking Macrophages to improve the Efficacy of BRAF inhibition, Gaston Habets; James Tsai; Elizabeth Burton; Bernice Matusow; Hoa Nguyen; Chao Zhang; Wayne Spevak; Prabha Ibrahim; Rafe Shellooe; Gideon Bollag;
  • (D094) Concerted Akt down-regulation determines efficacy of histone deacetylase and estrogen receptor inhibition in breast cancer cells, Scott Thomas; Kenneth Ted Thurn; Paromita Raha; Stephanie Chen; Pamela N. Munster;
  • (D095) Developing a molecular understanding of non-small cell lung cancer resistance to standard taxane-platin chemotherapy, Maithili P. Dalvi1; Carmen Behrens2; Milind Suraokar2; Luc Girard1; Yang Xie1; Ignacio Wistuba2; John D. Minna1;
  • (D096) A non-biologic nanoparticle paclitaxel (NBN-Pac) formulation with characteristics of albumin-based formulation - (nab-Pac), Kouros Motamed; Larn Hwang; Chao Hsiao; Vuong Trieu;
  • (D097) Quantifying hypoxia-modulated radiation-resistance in human glioblastoma in vivo, Russell Rockne1; Andrew Trister2; Maxwell Neal2; Kristi Hendrickson2; Maciej M. Mrugala2; Jason K. Rockhill2; Kenneth Krohn2; Kristin R. Swanson1;
  • (D098) Combination therapy of bevacizumab and rapamycin in antitumor activity, Lisa A. McPhatter1; Pierre Sonveaux2; O. Michael Colvin3; Bruce Klitzman3;
  • (D099) Development of an efficient RNAi-based therapy to treat KRAS-addicted tumors, Christof Fellmann1; Tina L. Yuan2; Chih-Shia Lee3; Cayde Ritchie2; Chang-Woo Lee3; Thomas Schleup4; Ji Luo3; Frank McCormick2; Scott W. Lowe5;
  • (D100) Investigating mechanisms of K-ras-independent growth in pancreatic cancer, Mandar Deepak Muzumdar; Pan-Yu Chen; Wen Xue; Kim Mercer; Harry Jenq; Tyler Jacks;
  • (D101) Dual mTOR and HSP90 targeted therapy in pancreas cancer, Lora A. Wilson; Colin D. Weekes;
  • (D102) Integration of OncoPanelTM high-content cell line profiling and univariate genomics analysis to discover and prioritize predictive biomarkers for cancer therapeutics, Michael Harges; Tom Arnold; Katie Snead; Alison R. Angione; Karen Bernards; Brian Nelson; Keith McKinley; Kate Waikins; Jonathan M. Crane; Usha Warrior; O. Jameel Shah;
  • (D103) Noninvasive identification of viable cell populations in docetaxel-treated breast tumors using ferritin-based magnetic resonance imaging, Woo Kyung Moon; YoonSeok Choi;
  • (D104) Novel antagonists that target the binding function 3 site of the androgen receptor, Ravi Munuganti; Eric LeBlanc; Nathan A. Lack; Peter Axerio; Kate Frewin; Emma Guns; Artem Cherkasov; Paul S. Rennie;
  • (D105) From bench to bedside: Challenges in molecular diagnostics for personalized oncology, Marzena A. Lewandowska1; Ewa Chmielowska2; Wojciech Jozwicki1;