American Association for Cancer Research

Continuing Medical Education (CME)

Cancer Susceptibility and Cancer Susceptibility Syndromes 2014


The American Association for Cancer Research (AACR) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education activities for physicians.


The AACR has designated this live activity for a maximum of 14.75 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Credit certification for individual sessions may vary, dependent upon compliance with the ACCME Accreditation Criteria. The final number of credits may vary from the maximum number indicated above.


Physicians and other health care professionals seeking AMA PRA Category 1 Credit(s)TM for this live continuing medical education activity must complete the CME Request for Credit Survey, below, by Monday, March 17, 2014. Certificates will only be issued to those who complete the survey. Your CME certificate will be sent to you via email after the completion of the activity.


The study of rare human genetic cancer susceptibility syndromes has led to a broader view of cancer pathogenesis, diagnosis, and treatment in the general population. The systematic study of rare cancer-prone families has elucidated a complex network of cancer proteins and tumor suppressors, many of which function in DNA repair, cell cycle checkpoint control, and telomere maintenance. For example, the Li-Fraumeni syndrome has illustrated how study of a rare familial cluster of pediatric sarcomas and breast cancer can provide a wider view of clinical genetics for both inherited and sporadic cancers.

Researchers and clinicians attending this conference will be exposed to research from a wide array of these susceptibility syndromes and discuss how the latest findings and future directions may be applicable across other syndromes. Separately, many of these susceptibility areas of research are too narrowly focused to attract a large audience for a conference. By combining several susceptibility syndromes into one program, the conference brings divergent, yet related, areas of research together to move the collective field forward.

Clinicians will leave this program with additional knowledge across all types of susceptibility syndromes, new ideas on how research into specific syndromes can be applied across other areas, and chemoprevention strategies that can be applied to those at risk. 

After participating in this CME activity, physicians should be able to:

  • Articulate how research obtained in one susceptibility syndrome can potentially be applied to another susceptibility syndrome;
  • Assess the current state of cancer susceptibility research – specifically Fanconi Anemia, Cowden Syndrome, TSC Syndrome, and Li-Fraumeni Syndrome; and
  • Explain the role of chemoprevention strategies for specific susceptibility syndromes.


It is the policy of the AACR that the information presented at AACR CME activities will be unbiased and based on scientific evidence. To help participants make judgments about the presence of bias, the AACR will provide information that Program Committee members and speakers have disclosed about financial relationships they have with commercial entities that produce or market products or services related to the content of this CME activity. This disclosure information will be made available in the Program/Proceedings of this conference.


This activity is supported by grants and will be disclosed at the activity.


Please contact the Office of CME at 215-440-9300 or