American Association for Cancer Research

Poster Sessions

POSTER SESSION A

Wednesday, November 6 • 12:30 p.m.-2:30 p.m.

(In alphabetical order, not board assignment order)

  • VIEW POSTER SESSION B
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    • A novel mouse model for inducible Prdm14 expression rapidly develops fully penetrant acute T-cell leukemia, Brandi Carofino
    • A novel, human-compatible mouse model for preclinical research on prolactin in breast cancer, Heather Christensen 
    • A p97 ATPase inhibitor with anti-proliferative, anti-inflammatory, and anti-thrombotic effects in vivo, Tsui-Fen Chou 
    • Advanced Avatar models for studying cancer stem cell dynamics in human pancreatic ductal adenocarcinoma, Christopher Heeschen 
    • Anticancer activity of KIOM-CRC#23, an ethanol extract of Korean medicine in tumor xenograft model using A549 lung cancer cell line, Jinhee Kim 
    • B cell lymphoma/leukemia 10-driven program in oral squamous cell carcinoma through STAT1/ATF4/S100P signaling pathway for tumor progression, Chang Cheng-Chi 
    • BAP1: An emerging player in epigenetics and cancer, Anwesha Dey 
    • BLM overexpression promotes tumorigenicity in an azoxymethane/dextran sulfate (AOM/DSS) murine model of intestinal cancer, Kenechi Ebede 
    • Canonical WNT/β-Catenin pathway activation supresses embryonal rhabdomyosarcoma growth and self-renewal, Eleanor Chen 
    • Clonal evolution enhances leukemia propagating cell activity in T-cell acute lymphoblastic leukemia through AKT/mTORC1 pathway activation, Jessica Blackburn 
    • Comparative drug exposures in mouse, dog and human CHOP protocols for lymphoma therapy, Daniel Gustafson 
    • Comparison of genes upregulated in metastasis with three C. elegans cell migrations, Mihoko Kato 
    • Delineating roles of Pten and Pik3ca in endometrial carcinoma using mouse models, Ayesha Joshi 
    • Development of a cloud-based histology database for collaborative cancer research, Ke Cheng 
    • Directing personalized breast cancer treatment with pathway signatures, Eran Andrechek 
    • Directing personalized breast cancer treatment with pathway signatures, Jing-Ru Jhan 
    • From melanocyte to melanoma: Identifying key molecular events at the onset of cancer, Charles Kaufman
    • Immunoglobulin heavy chain usage in canine CLL, Anne Avery 
    • In utero exposure to estrogen promotes mammary tumor risk in MMTV-erbB-2 transgenic mice through induction of ER-erbB-2 crosstalk, Amanda Blackwelder 
    • Insulin-like growth factor 2 mRNA binding protein 1 (IGF2BP1) drives growth, metastasis and chemoresistance in human and canine osteosarcoma, Deanna Dailey 
    • Interrogating therapeutic response for advanced prostate cancer in vivo using cross-species regulatory models, Nicolas Floch
    • Interspecies applications of gene expression-based prediction of chemosensitivity, Jared Fowles 
    • Interspecific recombination between orthologous human and mouse BAC clones in E. coli: Exploring scalable humanization of cancer-relevant genes in the mouse genome, David Bergstrom 
    • Knockdown of Integrin-linked kinase reduces invasive and metastatic potential of renal cell carcinoma, Kyung Seok Han 
    • Mammary-specific, doxycycline-regulated transposon mobilization for identifying driver genes in mouse models of breast cancer, Shelley Gestl 
    • Measuring autophagy inhibition as a pharmacodynamic response to hydroxychloroquine in a spontaneous canine lymphoma clinical trial, Rebecca Barnard 
    • Monocyte depletion to amplify tumor vaccine immunity in a dog non-Hodgkin lymphoma model, Steven Dow 
    • Notch signaling enhances self-renewal in embryonal rhabdomyosarcoma, Myron Ignatius 
    • Novel oncolytic adenovirus (ILV-19) induces apoptosis in BRAF inhibitor resistant (V600E) mutant melanoma cell lines 451lu-R and Mel1617-R, Farah Hedjran 
    • Novel prostate cancer patient-derived xenograft models of bone metastatic castrate-resistant prostate cancer, Christina Jamieson 
    • Pancreatic cancer patient-derived orthotopic xenograft (PDOX) is effectively targeted by Salmonella typhimurium A1-R, Robert Hoffman 
    • Patient-derived fluorescent orthotopic xenografts (PDOX) models for personalized anti-metastatic cancer therapy and drug discovery, Robert Hoffman 
    • Pharmacological approaches to metastatic disease using an inflammatory breast cancer model, Mary Alpaugh 
    • Phase I evaluation of anti-human leukocyte antigen-DR monoclonal antibody therapy in spontaneous canine lymphoma, Barbara Biller 
    • Progesterone signaling inhibits cervical cancer in mice, Sang-Hyuk Chung 
    • Quality control and quality assurance of canine biological specimens available through the Pfizer-CCOGC, Inc. National Biorepository for Comparative Oncology Studies, Jaime Modiano 
    • Quantitative and multiparameter analysis of tumor cell intravasation, Elena Deryugina 
    • Role of autophagy inhibition in metastatic disease utilizing mouse models, Ryan Hansen 
    • S6K1 promotes invasiveness of breast cancer cells in a novel model of triple-negative breast cancer metastasis, Yekaterina Khotskaya 
    • Studying circadian disruption as a novel risk factor of hepatocellular carcinoma using mouse models, Loning Fu 
    • Suppressor of cytokine signaling (SOCS)-3 and the C-X-C chemokines CXCL1 and CXCL2 promote tumor aggressiveness and radiation resistance in pancreatic cancer, Nicholas Cacalano 
    • Target non-random karyotype change: From yeast model to human tumors, Guangbo Chen 
    • Targeting NOTCH1 and C-MYC in humanized models of relapsed and induction failure pediatric T-ALL, Michelle Kelliher 
    • The impact of dose reduction upon local tumor control for stereotactic radiation therapy in an orthotopic rat model of osteosarcoma, James Custis 
    • The Mouse Tumor Biology (MTB) Database: An electronic tool for identifying and evaluating mouse and PDX models of human cancer. Dale Begley 
    • Therapeutic response of ovarian clear cell carcinoma using zebrafish xenografting, Dawn Cochrane 
    • Thymidylate Synthase overexpression accelerates pancreatic cancer development in a KRASG12D/+ mouse model, Rony Francois 
    • Towards validation of three-dimensional nuclear telomeric profiles as a biomarker of myelodysplastic syndromes and acute myeloid leukemias in a mouse model, Macoura Gadji 
    • Transgenic Onco-Pig cells mimic human cancer, Tiago Collares 
    • Understanding the impact of metabolic cold stress on the therapeutic response of tumors, Jason Eng 
    • Using a hypoxia-induced CSC tumor initiation model to improve predictive potential for patients with metastatic breast cancer, Emily Chen 

     

    POSTER SESSION B

    Thursday, November 7 • 4:30 p.m.-6:30 p.m.

    (In alphabetical order, not board assignment order)

    • Iqgap2-/- mouse as a model for advanced human hepatocellular carcinoma, Valentina Schmidt 
    • A genome-wide screen of C. elegans vulva reveals novel cell non-autonomous suppressive networks in the tumor microenvironment, Nicholas Sullivan 
    • A human-mouse xenograft model to evaluate therapies and study the role of TSLP-induced signals in Ph-like ALL, Kimberly Payne 
    • A large-scale transgenic screen in zebrafish identifies TOX as a novel oncogene in T-cell acute lymphoblastic leukemia, Riadh Lobbardi 
    • A new approach to optimizing the drug discovery and development pipeline for breast cancer, Isabelle Tancioni 
    • A novel immunocompetent murine model for replicating oncolytic adenoviral therapy, Lingzhi Zhang 
    • A portable imaging system for fluorescence-guided surgery on a human colon cancer patient-derived orthotopic xenograft (PDOX) nude mouse model, Robert Hoffman 
    • Abi1 levels regulate prostate tumor progression in mice downstream from Pten inactivation, Leszek Kotula 
    • Adult stem cell quiescence as a tumor suppressor mechanism in squamous tumors, Andrew White 
    • Antitumor activity of KIOM-CRC#5, an ethanol extract of Korean medicine, and its beneficial effect in combination with Cisplatin in two murine lung cancer models, Jinhee Kim 
    • Aspirin inhibits cyclooxygenase 2-mediated prostaglandin production and tumorigenesis in a preclinical model of tuberous sclerosis complex, Chenggang Li 
    • Ataxia telangiectasia mutated interactor regulates metastasis and acts as an independent prognostic marker in chromosomal instability and microsatellite instability colorectal carcinomas, Yueju Li
    • ATDC (Trim29) drives invasive bladder cancer formation, Phillip Palmbos 
    • Cell type-dependent functions of cysteine cathepsins in murine breast cancer progression, Christoph Peters 
    • Characterization of tumor-host interactions that promote liver metastasis of colorectal cancer, Maria Marjorette Pena 
    • CHD5 in tumor suppression: From chromosome engineered models to chromatin dynamics and the cancer clinic, Alea Mills 
    • Combinatorial activation of PI3-kinase and Ras-Raf signaling in mouse models of advanced prostate cancer, Jingqiang Wang 
    • CXCR4 inhibition in an orthotopic mouse model for small cell lung cancer (SCLC), Sanaz Taromi 
    • Development of a Feline PBPK model for investigating translational cancer drug therapies, Renee Lake 
    • Dissecting MDM2 function in medulloblastoma pathogenesis, Susan Mendrysa 
    • Gain of function contribution of mutant AKT-E17K to lung and mammary tumorigenesis in mouse models, Donatella Malanga 
    • Genetic interaction of NEDD9 with melanoma-prone oncogenes and tumor suppressor genes, Minjung Kim 
    • High-throughput screen identifies HDAC inhibitors as potent inhibitors of MYC-driven medulloblastoma, Yanxin Pei 
    • High-throughput synthetic lethal interaction screening in model organisms as a strategy for the identification of novel therapeutic targets in cancer, John Paul Shen 
    • In a patient-derived xenograft model of occult hepatic metastasis from pancreatic cancer the MEK inhibitor trametinib delays tumor outgrowth and prolongs survival, Timothy Newhook 
    • In vivo alteration of nucleoside pools does not lead to carcinogenesis but rather protects from fatty liver caused by anti-neoplastic agents, Giuseppe Pizzorno 
    • Knock-in mice with activated Alk display prolonged neurogenesis as a predisposition step to neuroblastoma, Lucille Lopez-Delisle 
    • Linking development and cancer modeling in zebrafish identifies putative therapeutic targets in medullary thyroid cancer, Jacques Villefranc 
    • Man's best friend for cancer driver-passenger discrimination, Shaying Zhao 
    • Mechanism and preclinical prevention of increased breast cancer risk caused by pregnancy, Yi Li
    • Modeling of early to invasive stages of pancreatic cancer progression with an iPSC-like line from human pancreatic ductal adenocarcinoma, Jungsun Kim 
    • Modifier genes and cancer susceptibility: Lessons from inbred mouse strains, Linda Siracusa 
    • Mouse models for cancer research available from The Jackson Laboratory Repository, Alicia Valenzuela 
    • Mouse models of Ewing's sarcoma and fusion-related sarcoma: Correct phenotypes and cell-of-origin, Takuro Nakamura 
    • MRI provides a more reliable method of esophageal tumor detection than endoscopy in a rat model, Juliann Kosovec 
    • Optimisation of an oncogenomics-based in vivo screen to validate candidate sarcoma genes, Timothy McKinnon 
    • Paclitaxel and carboplatin loaded pegylated liposomes for ovarian cancer, Hemal Tandel 
    • Paradoxical acceleration of pancreatic tumorigenesis through Smoothened inhibition: A post-clinical trial in genetically engineered mice, Kenneth Olive 
    • Patient-derived tissue culture model systems of renal cell carcinoma for development of clinically translatable metabolic biomarkers, Renuka Sriram 
    • Preclinical evaluation of a PARP inhibitor in mice representing genetically different subtypes of pancreatic cancers, Barbara Orelli 
    • RB function as a central component of osteosarcoma behavior: A comparative assessment in dogs and humans, Jaime Modiano
    • Rb1 and p53 deletion in Ascl1-expressing cells lead to the development of multiple tumors of neuroendocrine origin, Florent Suau 
    • RNAi mouse models: Revolutionizing drug discovery in vivo, Prem Premsrirut 
    • Simultaneous absolute quantization of ATP-binding cassette transporters in canine tissues via targeted proteomics, Luke Wittenburg 
    • Small-cell lung cancer-antigen HuD is prone to isoaspartylation: A novel opportunity for biological therapy of small-cell lung cancer, Mario Pulido 
    • Stem-like cells selected by serial in vivo orthotopic passage of human pancreatic cancer cells, Cristina Metildi 
    • Subcutaneous delivery of docetaxel and carboplatin accumulate preferentially in lymphatic circulation as compared to intravenous delivery in rats with surgically created lymph and venous fistulae, Deanna Worley 
    • Survivin inhibition via EZN-3042 in canine models of lymphoma and osteosarcoma, Jenette Shoeneman
    • Targeting the immune environment in humanized mice model of breast cancer, Te-Chia Wu
    • The Survivin-deltaEx3 isoform drives microvascular proliferation and malignant progression in proneural gliomas, Ganesh Rao 
    • Using magnetic resonance and hyperpolarized tracers to monitor solid tumor progression, metastasis and response to treatment, Stephen Lai