Poster Session C

SCHEDULE OF POSTER PRESENTATIONS

POSTER SESSION C

Tuesday, January 22, 12:45 p.m.-2:45 p.m.

(In alphabetical order, not board assignment order)

A macrophage autonomous α4β1integrin-Syk-Rac2 signaling axis controls macrophage differentiation, tumor growth and metastasis. Shweta Joshi, Moores UCSD Cancer Center, University of California, San Diego, CA
Aberrant promoter methylation of HOPX-β-, MUC1 genes and global methylation in esophageal squamous cell carcinoma. Ruei Nian Li, Kaohsiung Medical University, Kaohsiung, Taiwan
Activation of focal adhesion kinase by direct interaction with β-4 integrin in an EGFR-Src dependent pathway in tumor progression. Yu-Ling Tai, NAtional Taiwan University, Taipei, Taiwan
Akt-EphA2 Signaling Axis Promotes Diffuse Infiltrative Invasion of Glioma in vivo and Regulates Glioma Stem Cell Properties. Bingcheng Wang, Case Western Reserve University, Cleveland, OH
αvβ-6 integrin promotes a TGFβ1-mediated cancer cell autonomous osteolytic program through upregulation of matrix metalloproteinase 2 (MMP2). Anindita Dutta, Thomas Jefferson University, Philadelphia, PA
Angiotensin-(1-7) attenuates triple negative breast cancer growth and progression through regulation of protein phosphatases. Patricia Gallagher, Wake Forest School of Medicine, Winston-Salem, NC
Anterograde lysosome trafficking contributes to EGF-mediated tumor invasion. Samantha Dykes, Louisiana State University Health Shreveport, Shreveport, LA
Application of sensitive EMT reporter to identification of breast cancer stem cell-related genes. Kiyotsugu Yoshikawa, Kyoto University Graduate School of Medicine, Kyoto, Japan
Assessing the role of Wnt secretion in prostate cancer skeletal metastasis. Kenneth Valkenburg, Van Andel Institute, Grand Rapids, MI
Association of interferon-induced protein with tetratricopeptide repeats 1 gene family with human papilloma virus infection in patients with oral squamous cell carcinoma. Te-Chang Lee, Academia Sinica, Taipei, Taiwan
Axl signalling is required for stem cell traits and metastasis in breast cancer. James Lorens, University of Bergen, Bergen, Norway
Biomarkers of proliferation, survival, and migration of human breast tumor cells: future perspectives. Vivian Labovsky, Institute for Experimental Biology and Medicine, Buenos Aires, Argentina
Biomaterial scaffolds to engineer a pre-metastatic niche. Samira Azarin, Northwestern University, Evanston, IL
Blocking endogenous TBX2 expression abrogates Prostate cancer bone metastasis in a xenograft mouse model. Srinivas Nandana, Cedars-Sinai Medical Center, Los Angeles, CA
BLT2 promotes the invasiveness of breast cancer cells through upregulating IL-8 production. Lee A-Jin, Korea University, Seoul, Korea (Rep.)
Bone metastasis seed pre-selection by the primary tumor stroma. Xin Jin, Memorial Sloan-Kettering Cancer Center, New York, NY
Bone morphogenetic protein 7 regulates dormancy and recurrence of prostate cancer stem cell in bone. Fei Xing, University of Mississippi Medical Center, Jackson, MS
c-Abl and Arg are activated in human primary melanomas, promote melanoma cell invasion, proliferation, survival and drive metastatic progression. Sourik Ganguly, University of Kentucky, Lexington, KY
Candidate osteosarcoma metastatic drivers identified in highly clonal metastases using transposon-mediated insertional mutagenesis. Tracy Powell, University of Minnesota, Minneapolis, MN
Characterization of HGF-mediated EMT and its inhibition with novel HGF pathway inhibitors using transcriptomic analysis. Kevin Tuttle, Brigham Young University, Provo, UT
Characterization of metastatic cancer stem cells in osteosarcoma. Nino Rainusso, Texas Children's Cancer & Hematology Centers, Houston, TX
Correlated intrinsic breast cancer subtypes and expression of CD47 in BM predicts recurrence. Makoto Nagahara, Tokyo Medical and Dental Univesity, Tokyo, Japan
CRK protein domains diminish cell invasiveness of non-small cell lung cancer. Fariborz (Fred) Mortazavi, West Los Angeles VA/UCLA, Los Angeles, CA
CRMP1 functions to suppress epithelial-mesenchymal transition and invasion capacity of prostate cancer cells. Ganhui Cai, The Chinese University of Hong Kong, Hong Kong, Hong Kong, China
CXCL12-triggered amoeboid cell motility is mediated through a RhoA-directed signaling hub. Meghan Wyse, University of Toledo, Toledo, OH
CXCR4 Antagonist Inhibits Perineural Invasion of Adenoid Cystic Carcinoma in Preclinical Murine Model. Woo-Jin Jeong, Seoul National University Bundang Hospital, Seongnam, Korea (Rep.)
DEAR1 Orchestrates Selective Control over the Epithelial-Mesenchymal Transition Axis of TGFβ-?s Function. Nanyue Chen, UT MD Anderson Cancer Center, Houston, TX
Detachment of epithelial cells is driven by myosin-based contractility and RhoA. Jacob Hoj, Brigham Young University, Provo, UT
Down-regulation of IL-12 through IL-6 production increased cancer metastasis after radiotherapy. jinsil seong, yonsei university, Seoul, Korea (Rep.)
EMC1/KIAA0090 overexpression enhances proliferation and motility in breast cancer cells. Roberto Molina, University of São Paulo, Ribeirão Preto, SP, Brazil
ESRP1-CD44v-xCT Axis as a Potential Therapeutic Target for the Metastasis. Go Yoshida, School of Medicine, Keio University, Tokyo, Japan
Factors regulating sphere forming potential in osteosarcoma. Swathi Iyer, University of Kansas Medical Center, Kansas City, KS
FOXM1-dependent gene expression program controls cancer stem cell and metastasis properties of breast cancer cells. Anna Bergamaschi, University of Illinois at Urbana-Champaign, Urbana, IL
FRIZZLED7 and ERBB3 regulate distinct metastatic properties in melanoma. Shweta Tiwary, University of Rochester Medical center, Rochester, NY
Functional association of MDM2 Binding Protein with migratory and metastatic potential of hepatocellular carcinoma. Qian Bi, University of Kansas Medical Center, Kansas, KS
GD3 Synthase regulates EMT, CSC properties and metastasis in breast cancer cells. Tapasree Roy Sarkar, The University of Texas MD Anderson Cancer Center, Houston, TX
Gene silencing of c-met leads to brain metastasis inhibitory effects. Se Jeong Lee, Samsung medican center, Seoul, Korea (Rep.)
Gross appearance of hepatocellular carcinoma reflects expression of cancer stem cells, epithelial-mesenchymal transition and hypoxia related genes. Hyungjin Rhee, Department of Pathology, Brain Korea 21 Project for Medical Science, Yonsei University, Seoul, Korea (Rep.)
HAI-2 suppresses the tumor invasive growth of prostate cancer through regulation of matriptase. Chun-Jung Ko, Department of Biochemistry and Molecular Biology, College of Medicine, National Taiwan University, Taipei, Taiwan
High-content imaging facilities modeling of cancer epithelial-mesenchymal transition signaling network. xiaoping zhu, The Methodist Hospital Research Institute, Houston, TX
Hsp27 is required for EGF-induced epithelial to mesenchymal transition in prostate cancer. Amina Zoubeidi, Vancouver Prostate Centre, Vancouver, BC, Canada
Hugl1 loss may drive cancer stem cell transition. Joyce Schroeder, University of Arizona, Tucson, AZ
Human Melanoma Metastasis in NSG Mice Correlates with Clinical Outcome in Patients. Elena Piskounova, Children's Research Institute at UTSW Medical Center, Dallas, TX
Hypoxia-induced homodimerization of matrix metalloproteinase-9 in cancer cell migration. Ashleigh Pulkoski-Gross, Stony Brook University, Stony Brook, NY
Identification and characterization of serum biomarkers associated with metastatic progression of breast cancer. Adhari Al Za?abi, Brigham Young University, Provo, UT
Identification of RhoC as a novel binding partner for the metastasis suppressor RhoGDI2. Erin Griner, University of Virginia, Charlottesville, VA
Identifying Novel Genes Critical to Invasion in Head and Neck Squamous Cell Carcinoma. Sangeeta Jayakar, Albert Einstein College of Medicine, Bronx, NY
Integrin α6β-4 Promotes Autocrine EGFR Signaling to Stimulate Migration and Invasion toward HGF. Kathleen O'Connor, University of Kentucky, Lexington, KY
Integrin αvβ-3 drives stemness in the pregnant and neoplastic mammary gland. Jay Desgrosellier, University of California, San Diego, La Jolla, CA
Leptin increases the metastatic potential of breast cancer cells. Ameet Misrha, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, Australia
Lipid expression dynamics in epithelial cells undergoing HGF-induced EMT. Kristen Alexander, Brigham Young University, Provo, UT
Liver non-parenchymal cells drive metastatic breast cancer survival but fail to initiate mesenchymal to epithelial reversion. Donald Taylor, University of Pittsburgh, Pittsburgh, PA
Loss of DRAM2 in epithelial ovarian cancer promotes cell invasion. Eun-Ju Lee, Chung-Ang University School of Medicine, Seoul, Korea (Rep.)
Loss of haptotaxis facilitates invasion in LKB1-deficient melanoma. Keefe Chan, University of North Carolina-Chapel Hill, Chapel Hill, NC
Matrix metalloproteinase-1 (MMP-1) facilitates intravasation and vascular dissemination of human carcinoma cells by regulating the microarchitecture and permeability of intratumoral vasculature. Anna Juncker-Jensen, The Scripps Research Institute, La Jolla, CA
Membrane type-1 matrix metalloproteinase (MT1-MMP) is a potent regulator of cancer malignant progression through the heparin-binding EGF-like growth factor activation. Naohiko Koshikawa, Institute of Med Science, University of Tokyo, Tokyo, Japan
MenaINV dysregulation of receptor tyrosine kinase signaling. Madeleine Oudin, Massachusetts Institute of Technology, Cambridge, MA
MicroRNA-200 control of tumor cell cytoskeletal changes and invasion. Christin Ungewiss, UT MD Anderson Cancer Center, Houston, TX
MicroRNA-30c inhibits human breast tumor invasion and chemo-resistance by regulating TWF1 and IL-11. Huiping Liu, The University of Chicago, Chicago, IL
MicroRNA-424 promotes a mesenchymal-like phenotype while inhibiting breast cancer stem cell-like properties. David Drasin, University of Colorado Anschutz Medical Campus, Aurora, CO
MicroRNAs: master regulators of human tumor dormancy. Nava Almog, Tufts University School of Medicine, Boston, MA
miR-15b and its novel target, Metastasis suppressor 1 (MTSS1), are part of a global network of coding and non-coding EGF-stimulated genes. Merav Kedmi, Weizmann Institute of Science, Rehovot, Israel
miR-7 suppresses brain metastasis of cancer stem-like cells by modulating Kruppel-like factor 4 in breast cancer. Fei Xing, University of Mississippi Mecical Center, Jackson, MS
MLKs regulate the activities of the small GTPases, Rho and Rac, to drive both single cell and collective cell migration in breast cancer invasion. Chotirat Rattanasinchai, Michigna State University, East Lansing, MI
Molecular Determinants of the Intravasation Step in Cancer Metastasis. James Quigley, The Scripps Research Institute, La Jolla, CA
Nicotine triggers initiation and progression of K-Ras - driven pancreatic ductal adenocarcinoma. Christopher Heeschen, Spanish National Cancer Research Centre (CNIO), Madrid, Spain
N-Myc Interactor: A gatekeeper of malignant progression. Rajeev Samant, University of Alabama at Birmingham, Bimingham, AL
Non-lethal heat treatment of cells results in reduction in cancer stem cell fraction and metastatic potential. Yoo-shin Kim, The Methodist Hospital Research Institute, Weill Medical College of Cornell University, Houston, TX
Positive involvement of chemokine, CXCL14, in osteolytic bone metastasis of lung cancer. Haruo Iguchi, Shikoku Cancer Center, Matsuyama, Japan
Potential contributions of genome-stabilizing activity of NM23 to its metastasis suppressor function in melanoma. David Kaetzel, University of Maryland, Baltimore, MD
PROX1 promotes adaptation and growth of colon cancer macrometastases. Simone Ragusa, CePO, CHUV and University of Lausanne UNIL, Lausanne Ch-1006, Switzerland
PyVmT luminal and EMT cell lines exhibit characteristic patterns of orthotopic and tail vein metastasis. Lesley Ellies, University of California, San Diego, La Jolla, CA
Regulation of stemness by Hippo-YAP pathway under hypoxia in hepatocellular carcinoma. JI SU KIM, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea (Rep.)
Resistance to fluid shear stress is a conserved biophysical property of malignant cells. Michael Henry, University of Iowa College of Medicine, Iowa City, IA
Role of BLT2-STAT3-MMP2 Cascade in the Invasiveness and Meatastasis of Ovarian Cancer Cells. Soo Young Park, Korea university, Seoul, Korea (Rep.)
Role of β1,6 branched N linked oligosaccharides and associated terminal substitutions in organ specific metastasis. Manohar Dange, ACTREC, Kharghar, India
Screening cellular factors that mediate the development of CNS leukemia. Lizi Wu, University of Florida, Gainesville, FL
Src-beta catenin-SNAI1 axis is critical for the stemness and bone metastasis of E-cadherin lacking prostate cancer cells. Gagan Deep, Univeristy of Colorado Denver, Aurora, CO
Study of the relationship between RAR-beta2 hypermethylation and invasive esophageal squamous cell carcinoma. Ruei-siang Wu, Kaohsiung Medical University, Kaohsiung, Taiwan
Systemic and Stromal Support of Triple Negative Breast Cancer Progression is Prevented by EGF and IGF-1 Inhibitors. Zafira Castano, BWH, Harvard Medical School, Boston, MA
Targeted functional genomics screen for novel metastasis modulators in breast cancer. Angela Riedel, Molecular Oncology, University of Southern Denmark, Odense, Denmark
Targeting ROR1 Inhibits Epithelial-Mesenchymal Transition and Metastasis. Bing CUI, UCSD Moores Cancer Center, La Jolla, CA
Temozolomide-Perillyl Alcohol Conjugate Is Cytotoxic For Glioma Cancer Stem Cells. Niyati Jhaveri, University of Southern California, Los Angeles, CA
The critical roles of tumor initiating cell and lymph node stromal microenvironment in human colorectal cancer extra-nodal metastasis. Li Li, Ochsner Clinic Foundation, New Orleans, LA
The development of metastatic mouse models of neuroblastoma to bone and brain to identify the molecular mechanisms governing metastasis. Kelly Fathers, The Hospital for Sick Children, Toronto, ON, Canada
The effect of autophagy inhibition on anchorage independent cell growth. Rebecca Barnard, Colorado State University, Fort Collins, CO
The effect of differential expression of HES1 on the metastatic dormancy of osteosarcoma. Madonna McManus, MD Anderson Cancer Center, Houston, TX
The expression of CD44 isoform and xCT during epithelial?mesenchymal transition in hepatocellular carcinoma. Seung Jin Lee, Asan Institute for Life Science, Asan Medical Center, Seoul, Korea (Rep.)
The neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis. Kerstin Sinkevicius, Boston Children's Hospital, Boston, MA
The role of cancer heterogeneity in metastasis. Yoojin Shin, Korea University, Seoul, Korea (Rep.)
The role of c-MET and Her-3 receptor crosstalk in hepatocyte growth factor-induced cell migration in non-small cell lung cancer and breast tumor cells. Edgar Sanchez Palacios, Massachusetts Institute of Technology, Cambridge, MA
The role of the microRNA-200 family in the regulation of tumor cell signaling and metastasis in lung cancer. Jonathon Roybal, UT MD Anderson Cancer Center, Houston, TX
The seed and soil in bone metastasis: Cancer stem cells and extracellular matrix remodeling in a reconstructed metastasis (rMet) model of breast cancer. Mukti Parikh, Purdue University, West Lafayette, IN
Tissue Tranglutaminase Regulates β--Catenin Signaling in Ovarian Cancer Cells. Salvatore Condello, Indiana University School of Medicine, Indianapolis, IN
Transcriptional Coactivator MED1 in Mammary Tumor Progression, Metastasis and Cancer Stem Cell Formation. Xiaoting Zhang, University of Cincinnati, Cincinnati, OH
Tumor Progression Locus 2 (Tpl2) protein kinase contributes tumor growth and metastasis of renal cell carcinoma. Hye Won Lee, Samsung medican center, Seoul, Korea (Rep.)
WAVE3 is required for TGF-β-mediated EMT. Khalid Sossey-Alaoui, Cleveland Clinic, Cleveland, OH