American Association for Cancer Research

The Role of Telomeres and Telomerase in Cancer Research

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February 27-March 2, 2010
The Worthington, A Renaissance Hotel
Fort Worth, Texas


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CHAIRPERSONS:
Titia de Lange, Rockefeller University, New York, NY
Woodring E. Wright, UT Southwestern Medical Center, Dallas, TX
Virginia A. Zakian, Princeton University, Princeton, NJ

Consequences of deleting TRF2 which generates unprotected telomeres and causes the chromosomes to fuse together. This thus incarnates the theme of DNA damage and telomeres. Courtesy Woodring E. Wright, UT Southwestern Medical Center, Dallas, TX.

This will be the fourth AACR Special Conference to focus on the role of telomeres and telomerase in cancer research. A hallmark of previous conferences has been the large number of proffered papers included in the plenary sessions, which the organizers plan on continuing at the 2010 conference. The major objectives of this conference are to provide an overview of the field of telomeres and telomerase as these topics relate to cancer; to provide an overview of the current status of cancer research related to telomeres and telomerase; and to provide a forum for interaction, education, and synergy among cancer scientists and experts in the field of telomere biology. Importantly, this conference will provide a format for cancer researchers interested in learning the latest on telomere and telomerase biology that may pertain to their research program. The chairpersons hope to attract young investigators in the cancer field who seek ideas on how telomerase can be targeted in the clinic and to inspire researchers in the field of telomeres and telomerase to seek collaborations and other mechanisms to apply their research to the cancer problem. Session topics include: DNA repair and telomeres, mammalian models of telomere dysfunction, regulation of telomere chromatin, telomere biology in stem cells and cancer stem cells, telomeres and ALT mechanisms, telomeres and genomic instability, telomerase, and therapeutic approaches based on telomeres and telomerase. Previous conferences have drawn 250 to 300 researchers from around the world; please mark your calendar and plan to join us for this exciting program.