In a change from previous programs, the AACR 101st Annual Meeting 2010 will present a new major Plenary Session each morning from April 18 through April 21. Several speakers in these Plenary Sessions have recently published articles in AACR journals on topics related to their Plenary presentations. Free links to and summaries of these articles are available by clicking on the session links below. (See all Annual Meeting Plenary Sessions.)
Plenary Session 3: The Complexity of Cancer Tuesday, April 20, 2010; 8:15 AM-10:15 AM Featured Speaker: Joan S. Brugge"Mechanisms that control tumor cell anchorage"
Recent article from Dr. Brugge related to this topic:
Fibroblast growth factor receptor 1 (FGFR1) is frequently amplified and highly expressed in lobular carcinoma of the breast. Brugge and colleagues identify ribosomal S6 kinase as a critical component of FGFR1 signaling in lobular carcinoma and potential therapeutic target in FGFR1-expressing tumors. (Read more)
Plenary Session 2: The Cancer Genome Monday, April 19, 2010; 8:00 AM-10:00 AM Featured Speaker: Bert Vogelstein "The sequence of all 185,000 coding exons in each of 100 human tumors: What has it taught us?"
Recent article from Dr. Vogelstein related to this topic:
Large-scale sequencing of cancer genomes have identified thousands of genes not previously linked to tumorigenesis, but the functional relevance of the majority of these genes is not known. Vogelstein and colleagues describe a computational method to identify and prioritize missense mutations most likely to generate functional changes that enhance tumor cell proliferation. (Read more)