Plenary Session 8—Targeting Tumor Metabolism

Chairperson: Christian Dittrich, Ludwig Boltzmann Institute for Applied Cancer Research, Vienna, Austria

Wednesday, November 16, 10:30 a.m. – 12:30 p.m.

• Inhibition of the PI3K Pathway: Hope We Can Believe in?
• PI(3)King Apart PTEN’s Role in Cancer
• Rethinking the Warburg Effect with Myc Micromanaging Glutamine Metabolism
• Metformin Prevents Tobacco Carcinogen–Induced Lung Tumorigenesis
• Metformin Induces Both Caspase-Dependent and Poly(ADP-ribose) Polymerase-Dependent Cell Death in Breast Cancer Cells
• Dual inhibition of Tumor Energy Pathway by 2-deoxy glucose and metformin Is Effective Against a Broad Spectrum of Preclinical Cancer Models
• Metformin Decreases the Dose of Chemotherapy for Prolonging Tumor Remission in Mouse Xenografts Involving Multiple Cancer Cell Types
• Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?

Further information:

2011 Molecular Targets and Cancer Therapeutics