This award is presented to a scientist of international renown who has made a major scientific discovery in basic or translational research.
- 2013 Peter K. Vogt
- 2012 Robert A. Weinberg
- 2011 Pier Paolo Pandolfi
- 2010 Joseph Schlessinger
- 2009 Napoleone Ferrara
- 2008 Axel Ullrich
- 2007 Mina J. Bissell
- 2006 Tadatsugu Taniguichi
- 2005 Lewis C. Cantley
- 2004 Stanley J. Korsmeyer
- 2003 Mario Capecchi
- 2002 Carl-Henrik Heldin
- 2001 Elizabeth H. Blackburn
- 2000 Charles J. Sherr
- 1999 Carlo M. Croce
- 1998 Anthony J. Pawson