Recipients receive $2,000 to be spent in support of the scholars' participation and presentation of data at the AACR 102nd Annual Meeting 2011.
Congratulations to the 2011 recipients!
Huang Dachuan, Ph.D., National Cancer Centre Singapore, Singapore. Abstract #2806. Identification of a frequent mutation of the SWI/SNF complex gene, PBRM1, in clear cell renal carcinoma.
Gopa Iyer, M.D., Memorial Sloan-Kettering Cancer Center, New York, NY. Abstract #4846. Genomic analysis of high grade bladder cancer: Defining genetic subtypes and therapeutic targets.
Anchit Khanna, M.B.B.S., University of Tampere, Tampere, Finland. Abstract #4194. Constitutive DNA-damage signaling promotes cancer cell proliferation through Chk1-CIP2A pathway independent of ATM-ATR.
Eric S. Kim, M.D., University of Texas MD Anderson Cancer Center, Houston, TX. Abstract #2249. Use of telomere length and genetic variations in maintenance genes to predict risk of recurrence and survival in patients with early-stage non-small cell lung cancer.
Akinyemi I. Ojesina, M.D., Ph.D., Dana-Farber Cancer Institute and Broad Institute, Cambridge, MA. Abstract #949. PathSeq: A comprehensive computational tool for pathogen discovery by deep sequencing of human cancer tissues.
Trevor J. Pugh, Ph.D., The Broad Institute of MIT and Harvard, Cambridge, MA. Abstract #4756. Exome sequencing of 81 neuroblastomas identifies a wide diversity of somatic mutation.
Gerald Quon, M.Sc., University of Toronto, Toronto, ON, Canada. Abstract #4847. Purifying tumor gene expression profiles leads to predictive models of patient outcome.
Keiko Shinjo, M.D., Aichi Cancer Center Research Institute, Nagoya, Japan. Abstract #61. Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with clinical outcome of lung adenocarcinoma.
Hendrik Witt, M.D., German Cancer Research Center, Heidelberg, Germany. Abstract #4724. Identification of a CpG-island methylator phenotype (CIMP) in a subgroup of pilocytic astrocytoma with favorable prognosis.
Janghee Woo, M.D., Dana-Farber Cancer Institute, Boston, MA. Abstract #3106. Intestinal mesenchymal fibroblasts promote early epithelial tumorigenesis through activation of integrin beta4 and receptor tyrosine kinases, bypassing common mutational mechanisms.
Award recipients are required to pay the Annual Meeting registration fee and make their own travel and housing arrangements. Therefore, all applicants are encouraged to register immediately to take advantage of the reduced advance registration rates. Booking travel and housing early will also ensure that the lowest rates will be available.
If an award recipient is unable to attend the Annual Meeting or will not be the presenter of the abstract, the award must be forfeited.
2010 AACR-GlaxoSmithKline Outstanding Clinical Scholars
Kelly L. Bolton, M.S., University of Cambridge, Cambridge, United Kingdom. A genome-wide association study of ovarian cancer prognosis identifies a novel locus for aggressive serous cancer on 19p13
Diana T. Lau, M.S., Children's Cancer Institute Australia, Australia. Reduced folate carrier gene polymorphism (RFC 80G>A): Associations with clinical outcome in NMYC amplified neuroblastoma patients
Emil Lou, M.D., Ph.D., Memorial Sloan-Kettering Cancer Center, New York, NY. Tunneling nanotubes facilitate intercellular communication and trafficking between mesothelioma cells
Stephen T. Oh, M.D., Ph.D., Stanford University School of Medicine, Stanford, CA. Mutation of the inhibitory adaptor protein LNK drives potentiated JAK-STAT signaling in patients with JAK2 V617F-negative myeloproliferative neoplasms
Colin Rogers, Ph.D., University of Florida, Gainesville, FL. Two novel insertion polymorphisms of the BRM gene are associated with loss of BRM expression and lung cancer risk
Jesse J. Salk, B.S., University of Washington, Seattle, WA. Clonal expansions as a biomarker of preneoplastic processes in ulcerative colitis
Saskia J. Santegoets, Ph.D., VU Medical Center, Amsterdam, Netherlands. T cell activation in relation to clinical responsiveness in patients with metastatic hormone-refractory prostate cancer receiving combined prostate GVAX and anti-CTLA4 immunotherapy
Ehsan Sarafraz-Yazdi, M.S., State University of New York, Brooklyn, NY. MDM2 protein variants expression in the plasma membrane of cancer cells; A target for anti-cancer peptide PNC-27
Sebastian Schwind, M.D., The Ohio State University, Columbus, OH. Higher MN1 expression is an unfavorable prognosticator in older patients (pts) with Cytogenetically Normal Acute Myeloid Leukemia (CN-AML): A CALGB Study
Anita G. M. Stam, B.S., Vrije Universiteit Medical Center, Amsterdam, Netherlands. Increased type-2 T cell rates and coincidence of Th17 spikes with autoimmune events and PSA declines upon combined prostate GVAX and anti-CTLA4 immunotherapy
Addy van de Luijtgaarden, M.D., Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands. Prognostic relevance of the RANK/RANKL/OPG triad and the IGF1R pathway in osteosarcoma
Hendrik Witt, M.D., German Cancer Research Center, Molecular Genetics of Pediatric Brain Tumors, Heidelberg, Germany. Subgroup-specific molecular alterations may explain the tremendous clinical heterogeneity of intracranial ependymoma
2009 AACR-GlaxoSmithKline Outstanding Clinical Scholars
Mark M. Aloysius, M.B.B.S., University of Nottingham, United Kingdom, Generation in vivo of enhanced of human telomerase reverse transcriptase (hTERT) peptide (p540 or p865) specific CD8+ T cell response is best achieved by vaccination with peptide-pulsed dendritic cells (DCs) activated and matured in vitro with TNF-α but l
Uchechi Anyanwu, B.S., Penn State University, PA, Elevated pretreatment serum TIMP-1 level predicts reduced PFS and overall survival in trastuzumab-treated metastatic breast cancer patients
Gerhardt Attard, M.D., Institute of Cancer Research and the Royal Marsden NHS Foundation Trust, United Kingdom, Molecular characterization of circulating tumor cells (CTC) from castration-resistant prostate cancer (CRPC) patients (pts) treated with abiraterone acetate (AA)
Sheetal V Bajaj, M.D., Childrens Hospital Los Angeles, CA, Identification of a putative biomarker that uniquely characterizes translocation-positive alveolar rhabdomyosarcomas
Jayshree L. Hirpara, M.B.B.S., National University of Singapore, Singapore, Mislocalization of Apaf-1 as a mechanism of drug resistance in B-cell lymphoma
Jose A. Karam, M.D., UT Southwestern Medical Center, TX, Prognostic value of Survivin in patients with bladder cancer
Jung Eun Lee, Sc.D., Brigham and Women's Hospital and Harvard Medical School, MA, Folate intake and the risk of colorectal cancer and adenoma in two large prospective studies: modification by time
Anne Marie McKnight, B.S., Johns Hopkins School of Public Health, MD, Racial and socioeconomic disparities in cervical cancer mortality in New York City, 1995-2006
Rohit Mehra, M.D., University of Michigan, MI, The role of TMPRSS2: Ets gene fusions in androgen independent metastatic prostate cancers
Anirban P. Mitra, M.D., University of Southern California Keck School of Medicine, CA, Associations of smoking and non-steroidal anti-inflammatory drug use with molecular alterations in urinary bladder cancer
Mahsa Mohebtash, M.D., National Cancer Institute, MD, Clinical outcomes following immunotherapy with a MUC1/CEA vaccine in patients with metastatic breast and ovarian cancer
Alexei Morozov, M.D., Ph.D., Memorial Sloan-Kettering Cancer Center, NY, Mesenchymal stem cell features of sarcoma cell lines and primary cultures
Leon Raskin, Ph.D., University of Michigan, MI, HMGA2 is a novel prognostic factor in melanoma
April A. N. Rose, B.S., McGill University, Canada, Translational relevance for ADAM-10 mediated shedding of GPNMB/Osteoactivin, a novel mediator of recurrence in triple negative breast cancers
Gerald Y. Tan, M.D., Weill Medical College of Cornell University, NY, Multiphoton microscopy imaging of periprostatic architecture from fresh human prostatectomy specimens: Promising potential for improving cancer clearance and potency outcomes during nerve-sparing radical prostatectomy
Tonya C. Walser, Ph.D., David Geffen School of Medicine at University of California Los Angeles, CA, Snail at the intersection of inflammation, EMT, and early lung cancer development: A possible marker of the field cancerization effect
Lingzhi Zhang, Ph.D., University of California San Diego, CA, Expression of cyclic nucleotide phosphodiesterase 7B: a novel biomarker and prognostic indicator in chronic lymphocytic leukemia