American Association for Cancer Research

2004 AACR Minority Scholars in Cancer Research Annual Meeting

A. Deloris Alexander, Ph.D.

A. Deloris Alexander, Ph.D.

University of North Carolina, Chapel Hill, NC

“Eventually my plans are to accept a faculty position at a historically black college or university that has alliances with other research-intensive institutions.”

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Johnny O. Alexander, M.D.

Franklin Square Hospital, Baltimore, MD

“My ultimate goal is to be an academic physician.”

Nicolas G. Azios, B.A.

Nicolas G. Azios, B.A.

University of Texas, Austin, TX

“My long-range professional goals include an incorporation of research and academic teaching with a focus on undergraduate instruction.”

Abstract #2864. Novel Resveratrol-mediated Signaling Pathway Induces Filopodia Extension and Inhibits Cell Migration in MDA-MB-231 Human Breast Cancer Cells

Joe Barber, Jr., B.S.

Joe Barber, Jr., B.S.

University of Michigan, Ann Arbor, MI

“My major goal is to become a leading researcher in the field of cell cycle regulation, particularly how it relates to cancer.”

Abstract # 2972. Induction of p53R2 by dFdCyd Does Not Prevent R2 Expression

Brittnaie J. Bell, B.S.

Brittnaie J. Bell, B.S.

University of South Carolina, Columbia, SC

“My current career objective is to become a research professor at a university where I can also write grants in the interest of minority high school and undergraduate students to obtain research experience.”

Abstract # 1026. Effects of Phosphorylation of Human Thymidylate Synthase by Casein Kinase 2 on Ligand Binding

Anastacia C. Berzat, B.S.

Anastacia C. Berzat, B.S.

University of North Carolina, Chapel Hill, NC

“My long-range goal is to become an academic researcher in cancer biology.… I would like to obtain a tenure track position at a university where I could continue researching relevant topics in cancer and teach students to appreciate the role that biomedical research plays in increasing our understanding of cancer initiation, progression, and maintenance.”

Abstract # 343. Transforming Activity of the Rho Family GTPase, Wrch-1, a Wnt-regulated Cdc42 Homolog, is Dependent on a Novel C-terminal Modification

Alice B. Brown, M.D., Ph.D.

Alice B. Brown, M.D., Ph.D.

Massachusetts General Hospital, Boston, MA

“I am committed to a career in academic medicine.”

Emiro E. Caicedo-Granados, M.D.

Emiro E. Caicedo-Granados, M.D.

University of Minnesota, Minneapolis, MN

“My research goal is to be an independent researcher in head and neck cancer in an academic institution.”

Miquella G. Chavez, B.A., B.S.

Miquella G. Chavez, B.A., B.S.

University of New Mexico, Albuquerque, NM

“My current career goals include developing my skills as both a scientist and an educator.”

Sarah L. Claud, M.P.H.

Sarah L. Claud, M.P.H.

Henry Ford Health System, Detroit, MI

“After completing the requirements for my doctoral degree, I will continue working in the field of cancer epidemiology, prevention, and control….I will strive to bring cancer prevention efforts to underserved areas across the country and to make breakthroughs that will benefit millions of individuals that suffer from and are at risk for cancer.”

Abstract # 4019. Racial Differences in the Prevalence of Her-2/neu Positive Tumors

Juliet Michelle Daniel, PH.D.

Juliet Michelle Daniel, PH.D.

McMaster University, Hamilton, Ontario Canada

“My career goal is to establish a strong, internationally recognized laboratory and become a successful cancer research scientist.”

Selina F. Darling-Reed, Ph.D.

Selina F. Darling-Reed, Ph.D.

Florida A&M University, Tallahassee, FL

“I have a dual purpose in realizing my career goals. The first is to establish myself as a well- known and published scientist. The second is to work and encourage the development of young scientists in the African-American community.”

Robert J. Diaz, Ph.D.

Robert J. Diaz, Ph.D.

University of California, San Francisco, CA

“My career objective is to establish myself as an independent research scientist at an NCI- designated Cancer Center continuing my research towards understanding critical components of the ECM and regulating malignant outcome.”

Abstract # 3428. Type I Collagen Remodeling Regulates Keratinocyte Malignant Potential

Tracy M. Downs, M.D.

Tracy M. Downs, M.D.

University of California, San Diego, CA

“My long-term career and research goals include studying the molecular characterization of prostate cancer in a heterogeneous population of men with prostate cancer who undergo surgery at our institution.”

Cecilia A. Fernández, Ph.D.

Children’s Hospital Boston/Harvard Medical School, Boston, MA

“My goal over the next few years is to gain experience in using a variety of biochemical and in vivo assays for the study of angiogenesis and tumor development, which will ultimately provide me the opportunity to establish a career in academic science.”

Abstract #2298. Characterization of the Anti-angiogenic Effects of TIMP-4

Theodore O. Garnett, M.S.

Loma Linda University, Loma Linda, CA

“I have a passion for acquiring and imparting knowledge and my long-term goal is to become a medical scientist. As a medical scientist I will seek to advance biomedical science through research, both clinical and basic, as well as to disseminate the knowledge I have acquired through teaching and the publication of my findings.”

Abstract # 3223. Modulation of the TRAIL Apoptotic Pathway by Human Papillomavirus 16 E6

Monique A. Gary, B.S.

Fox Chase Cancer Center, Philadelphia, PA

“I anticipate launching a successful career as a surgical oncologist, and
coordinating/contributing to clinical and translational cancer studies aimed at developing effective chemopreventive agents for at-risk populations, active recruitment and retention of minorities for clinical trials, and defining the molecular basis for the differential patterns in cancer incidence and mortality between racial/ethnic groups, which to date have been well documented but not well understood.”

Katherine L. Glover, B.S.

Meharry Medical College, Nashville, TN

“My career objective is to practice medicine in an underserved population while conducting basic research on the molecular basis of cancer initiation and progression.”

Bianca P. Gomez, M.S.

Lombardi Cancer Center at Georgetown University Medical Center, Washington, DC

“My long range educational and research goals are to successfully complete my doctoral degree…, to pursue postdoctoral training where I would like to pursue an independent research project, publish several papers in renowned journals, and obtain an investigator’s grant.”

Abstract # 1213. Human X-Box Binding Protein in Antiestrogen Resistance

German G. Gomez, B.S.

University of Colorado Health Sciences Center, Denver, CO

“As an independent researcher, I would like to continue exploring adjuvant immune therapy strategies for the treatment of malignant gliomas.”

Abstract # 689. Human Glioma Cell Models Resistant to Alloreactive Cytotoxic T

Tisheeka R. Graham, B.S.

Tulane University, New Orleans, LA

“As a research scientist, I plan to work in an academic setting, which would allow me to conduct research as well as teach molecular biology and cancer biology courses.”

Mario R. Green, M.S.

Florida A&M University, Tallahassee, FL

“I am dedicated and obligated to becoming a prominent researcher and educator in hopes of preventing and finding a cure to cancer, as there is a need for more minority leadership at this level.”

Abstract # 2237.Diallyl Sulfide Inhibits DES-induced DNA Adducts in the Breast of Female ACI Rats

Loleta D. Harris, Ph.D.

UT M.D. Anderson Cancer Center, Houston, TX

“My goal is to do work that will ignite and inspire others to love science and become great researchers. Ultimately, I will strive to gain tenure in a faculty position at an undergraduate college or university.”

Abstract # 3273. Identification of AN43, a Tumor Associated Antigen Found in Bladder Cancer

Ralph A. Highshaw, M.D.

UT M.D. Anderson Cancer Center, Houston, TX

“I am in pursuit of an academic career as a surgeon/scientist.”

Reginald Hill, B.S.

University of North Carolina, Chapel Hill, NC

“My long-term career goal is to establish myself as a principal investigator scientist in a faculty position at a major university working on translational research…I hope to bolster the number of not only minority students, but undergraduate students in general, who choose to pursue an exciting and fulfilling career in scientific research by teaching and mentoring interested students.”

Abstract # 4299. Investigating the Role of the Rb Pathway in Prostate Tumor Suppression

Cimona V. Hinton, B.S.

Meharry Medical College, Nashville, TN

“My goal is to establish a career in cancer research in cell signaling and subcellular localization, publish world-class scientific findings, and train more minority students and postdoctoral fellows.”

Elizabeth A. Hopper-Borge, Ph.D.

Fox Chase Cancer Center, Philadelphia, PA

“My long-range research goal is to continue elucidating the roles that MRP subfamily members play in drug resistance as well as investigating their physiological roles in vivo models as a faculty member in a cancer center such as Fox Chase Cancer Center or a large research university.”

Romyla S. Ilagan, B.S.

University of California, Los Angeles, CA

“My career goal is to study the mechanisms underlying the transformations of normal cells to cancer cells and to study molecular markers which could be targeted as part of chemotherapy.”

Abstract # 208.Interrogating Androgen Receptor and MAPK Function in Androgen Independent Prostate Cancer by Optical Imaging with Two-Step Amplification Systems

Tilahun Jiffar, Ph.D.

University of Texas Health Science Center, Houston, TX

“I am encouraged to continue my investigation into molecular targets for chemotherapy with the full awareness that my dedication to my success depends upon the extra encouragement from professionals who have been involved in this field for quite some time.”

Abstract # 3367. PKC alpha Promotes Chemoresistance in Acute Lymphoblastic Leukemia Derived REH Cells by a BCL-2 Dependent, MAPK-Independent Mechanism

Kara R. Jones, M.S.

Virginia Commonwealth University, Richmond, VA

“My long-term goal is to be an independent researcher and faculty member in an academic institution.”

Abstract # 2412. Ionizing Radiation-induced Senescence of Breast Tumor Cells is
Dependent on p53 and Associated with Telomere Dysfunction

Kathie-Ann P. Joseph, M.D.

Columbia Presbyterian Medical Center, New York, NY

“I hope to develop and acquire the skills necessary to become an independent researcher so that I can become a role model to other minority scientists who wish to develop careers in research. I also wish to engage in translational research that can be taken directly to the clinical setting and have a positive impact on women with breast cancer, particularly, African- American women.”

Celina G. Kleer, M.D.

University of Michigan, Ann Arbor, MI

“One of the main goals in my career is teaching, especially undergraduate and medical students. I would like to pass on my knowledge and experiences to students, and be able to advise them and help them thrive in their careers, the same way my mentors are helping me.”

Abstract # 3287. Validation of RhoC-GTPase Expression as a New Tissue Biomarker in Breast Cancer

Bernard Kwabi-Addo, Ph.D.

Baylor College of Medicine, Houston, TX

“My long-term career goal is to establish a diagnostic laboratory where I can utilize my scientific expertise in cancer research to develop early detection prognostic markers, develop novel therapeutic modalities and contribute to understanding the basic molecular mechanisms of cellular transformation and tumor progression.”

Abstract #4811. Sprouty1, An Inhibitor of Fibroblast Growth Factor Signal Transduction, Is Down-regulated in Prostate Cancer

Magaly Martinez-Ferrer, Ph.D.

Vanderbilt University Medical Center, Nashville, TN

“I would like to be a professor and researcher at an academic and/or research institution. I want to continue working in the area of integrins and breast cancer.”

Abstract # 1524. Lycopene Reduces Incidence of Azoxymethane Induced Colon Tumors in Fisher 344 Male Rats During Initiation and Progression Stages

Jacquline A. Mason, B.S.

Howard University, Washington, DC

“I aspire to train other students, in the capacity of professor on the college level, with goals of having a major function in understanding the initiation, growth, progression, and treatment of cancer and racial disparities.”

Abstract # 1832. Analysis and Comparison of Matrix Metalloproteinases in Breast Cancer in African American and Caucasian Women

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Abstract # 5135.Combination Therapy of Ad-mda-7 and Herceptin Inhibits Tumor Growth in Nude Mice and Increases Apoptosis in Her2/neu Overexpressing Breast Cancer Cells

Karl E. Miletti-Gonzalez, Ph.D.

UMDNJ/The Cancer Institute of New Jersey, New Brunswick, NJ

“My career objectives in cancer and biomedical research are summarized by two of the most important aspects of a Ph.D. scientist – independent investigation and teaching/mentoring.”

Abstract # 1823.CD44 Up-regulates the Expression of Matrix Metalloproteinases (MMPs) in Ovarian and Breast Carcinoma Cells

Gustavo A. Miranda, Ph.D.

University of California, Los Angeles, CA

“My goal, in the short term, is to continue to expand my knowledge and training in the field of cancer research as it pertains to mammary epithelial neoplastic transformation.”

Abstract # 4808.Wnt10b Signaling Mediates Cell Cycle Regulators in Mammary Tumor Progression and Functions as a General Antagonist of TGF-_1 Cell-cycle Arrest

Gay S. Morris, B.S.

Howard University, Washington, DC

“I will enter academia as a professor of molecular biology and biochemical genetics. I will become an independent investigator who mentors both undergraduate and graduate students in the research laboratory.”

Abstract # 5201. THP-1 Macrophages Stimulate Proliferation, Protect Against Tamoxifen Killing, and Modulate Angiogenesis-related Gene Expression in MCF-7 Breast Cancer Cells

Lisandra Negrón-Vega, B.S.

University of Puerto Rico, San Juan, PR

“After finishing my Ph.D. studies, I would like to continue postdoctoral studies in the U.S. to strengthen my knowledge and to become an independent investigator.”

Abstract # 182. The Expression of a 110-kD Isoform of EGFR in MCF7I is Regulated by EGF and PMA

Chinonye C. Nnakwe, B.S.

University of Chicago, Chicago IL

“The health disparities between African-Americans and mainstream America are
unacceptable. I want to join the growing network of scientists working to amend these disparities and contribute to the development of effective cancer therapeutics for all patients.”

Abstract # 2656.Characterization of the DNA Ligase IV BRCT Domains and Their Role in DNA Double-Strand Break Repair

Onyinye F. Nwagbara, M.S.

Florida A&M University, Tallahassee, FL

“My career ambitions are to teach in a university, conduct scientific research, mentor, and work toward sustaining and preserving our environment.”

Esther A. Obeng, B.S.

University of Miami School of Medicine, Miami, FL

“My ultimate career goal is to be a part of a translational research team at a university affiliated hospital.”

Abstract # 4012.Proteasome-inhibitor Induced Apoptosis in Multiple Myeloma Cells Involves Endoplasmic Reticulum Stress and the unfolded Protein Response

Abena A. Otchere, B.S.

McMaster University, Hamilton, Ontario, Canada

“My long-term career goal is to obtain a Ph.D. and establish an independent laboratory with a focus on a relevant aspect of cancer biology so that I may contribute to the biological understanding and elimination of the disease.”

Abstract # 2404.The POZ-ZF Transcription Factor Kaiso Regulates CyclinD1 Expression in Breast Tumor Cells

Manuel Luis Penichet, M.D., Ph.D.

University of California, Los Angeles, CA

“Currently, I have two active cancer projects. I intend to further develop these projects in the future, bridging both basic and clinical cancer research.”

María Pérez-Lamigueiro, B.S.

University of North Texas Health and Science Center, Fort Worth, TX

“My goal is to put knowledge, experience, abilities, and enthusiasm together to help produce understanding and solutions to the fundamental problems related to cancer.”

Abstract # 1583. Changes in Mammalian Chromatin Structure as a Function of Protein-poly(ADP-vibosyl)ation. Susceptibility of Interphase Chromatin to Enzymatic Digestion with Deoxyribonuclease I (DNase I) and Microccocal Nuclease (MNase)

Chelsea Camille Pinnix, B.S.

The Wistar Institute/University of Pennsylvania, Philadelphia, PA

“I am confident that my ability, drive, and training will serve to make me a successful physician scientist.”

Abstract # 4938. Dissecting the Role of Tyrosine Receptor Kinase Ligand Pair,
EphA2/Ephrin A1, in Cultured Endothelial Cells

Juan M. Ramos, M.D.

Ponce School of Medicine, Ponce, PR

“My research career goals include having my own laboratory focused in cancer research.”

Abstract # 2892. UV Dose and DNA Repair Capacity Predict Non-melanoma Skin Cancer Risk

Walter Rayford, M.D., Ph.D.

LSU Health Sciences Center, New Orleans, LA

Jonathan Rios-Doria, B.S.

University of Michigan, Ann Arbor, MI

“Though I am still undecided whether I want to pursue a career in academia or industry, I do want to continue in the field of cancer research. I hope to engage in a challenging post-doctoral position that will help me clarify my career choice.”

Abstract # 1442.Proteolytic Regulation of B-Catenin by Calpain and Potential Role in Cancer

Lupe G. Salazar, M.D.

University of Washington, Seattle, WA

“My commitment to pursuing a career as a physician/scientist stems from my desire to use scientific data obtained at the bench to answer clinically relevant questions. In addition, it would allow me to nurture my love and enthusiasm for teaching and serving as a role model.”

Abstract # 1414.Long Term Immunity after Immunization with a HER-2/neu Vaccine

John A. Sandoval, M.D.

Indiana University School of Medicine, Indianapolis, IN

“I intend to pursue a career in pediatric surgery and be involved in an academic research position.”

Abstract # 2725. Mutagenic Activity of Human Neuroblastoma vs. Neural Stem Cell Precursors

Rita E. Serda, M.S.

University of New Mexico, Albuquerque, NM

“My goal is to become a professor at the university level, where I can teach and conduct independent research and assume the overarching responsibility for research projects.”

Abstract # 968.Cytochrome P450 24R-Hydroxylase Regulation in Prostate Cancer

Adrienne J. Smith, M.S.

Wake Forest University, Winston-Salem, NC

“I would pursue a teaching position in higher education. I want to teach at this level because we as African American females are truly a minority in this field. I believe if one is passionate enough about a particular topic then it is translated in their delivery of the subject.”

Abstract # 5177. Anti-apoptotic Signaling of Epidermal Growth Factor in Prostate Cancer

Sharon L. Steele, M.S.

Howard University, Washington, DC

“My primary career objective is to establish a research career in psycho-oncology with an emphasis on improving screening, treatment, and consequently, the quality of life for women with breast cancer or who are at high-risk for developing the disease.”

Tamara A. Tatum-Broughton, B.S.

Howard University, Washington, DC

“My major career goal is to be involved in research projects that focus on cervical cancer and/or metastasis. It is my preference to be employed as a scientific investigator in the pharmaceutical industry.”

Abstract # 5053.Molecular Gene Expression Profiles of Gelatinases During Neoplastic Progression of Cervical Epithelial Cells

Jean-Claude Twizere, Ph.D.

Gembloux Agricultural University, Gembloux, Belgium

Abstract # 235.The Homeobox Protein MSX-2 Interacts with Bovine Leukemia Virus Tax

Teneille Denise Walker, B.S.

Virginia State University, Petersburg, VA

“I want to be one of those hands who help cure patients affected by any of the types of cancers invading families.”

Valerie G. Walker, D.V.M.

West Virginia University, Petersburg, VA

“Upon completion of my post-doctoral training, I wish to obtain a full-time researcher position with the National cancer Institute and focus on the cytoskeleton and its role in angiogenesis and tumorigenesis.”

Abstract # 3529. AFAP-110 is a Prospective Binding Partner for the p85-alpha Subunit of PI3K

Douglas F. White, M.S.

Howard University College of Medicine, Washington, DC

“Ultimately, I will pass my experience and knowledge on through a teaching position in biology at the post-secondary educational level.”

Shalmica R. Williams, B.S.

University of Kansas, Kansas City, KS

“I aspire to become a professor of physiology pursuing interests in molecular carcinogenesis at a research-oriented academic institution.”

Abstract # 2517.Reduction of Cytotoxic T-Lymphocyte Effector Cells During Ovarian Cancer Progression by TCDD: Possible Mechanism of Immunosuppression

Jamie Lynn Wood, B.S.

Mayo Graduate School, Rochester, MN

“As a biomedical research scientist, I will apply and accept a position as an investigator with full teaching and research privileges at a biomedical research institution.”

Haile F. Yancy, Ph.D.

Howard University, Washington, DC

“I have a strong desire to teach and a goal of someday teaching at a university.”

Clayton C. Yates, III, M.S.

University of Pittsburgh School of Medicine, Pittsburgh, PA

“My decision to be trained in a career of biomedical research is based on the assurance that will be able to appreciate and master the unanswered questions associated with research.”

Abstract # 939.Direct Visualization of Prostate Cancer Progression Utilizing a Bioreactor

Ofelia L. Zegarra-Moro, M.D.

Mayo Clinic, Rochester, MN

Abstract # 1840.Blockage of Androgen Receptor Signaling Correlates with Enhanced Vimentin