Elizabeth M. Jaffee, MD, FAACR
Deputy Director, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Robert H. Vonderheide, MD, DPhil
Director, Abramson Cancer Center of the University of Pennsylvania; Hanna Wise Professor in Cancer Research, University of Pennsylvania Perelman School of Medicine
Pancreatic ductal adenocarcinoma (PDA) is resistant to most forms of therapy and is one of the most deadly types of cancer. The environment that surrounds cancer cells is referred to as the tumor microenvironment. Studies in mice and humans have shown that the PDA tumor microenvironment has unique characteristics that are thought to limit the efficacy of treatment.
Margaret A. Tempero, MD, University of California, San FranciscoLisa M. Coussens, PhD, Oregon Health & Science UniversityDavid C. Linehan, MD, Washington University in St. LouisDafna Bar-Sagi, PhD, NYU Langone Medical CenterIrving L. Weissman, MD, Stanford UniversityDouglas T. Fearon, MD, University of Cambridge, United KingdomSteven D. Leach, MD, Memorial Sloan Kettering Cancer Center
Betty BooherStuart RickersonRichard Vague