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FINDING CURES TOGETHER<sup>SM</sup>

AACR Annual Meeting 2019

NextGen Stars 

The NextGen Stars program provides an exciting opportunity to increase the visibility of early-career scientists at the AACR Annual Meeting and to support the professional development and advancement of those selected as AACR NextGen Stars.

Congratulations to the 2019 NextGen Stars!

Wendy Béguelin, PhD
Assistant Professor of Pharmacology
Weill Cornell Medical College

The role of EZH2 gain of function mutations in lymphomagenesis

Special Session
NextGen Stars Spotlight 1: Genetics and Immunology
Sunday, March 31, 2019


Laura W. Bowers, PhD
Assistant Professor
Purdue University

Obesity-associated leptin signaling promotes chemotherapy resistance in triple-negative breast cancer: The role of tumor-initiating cell enrichment
 
Major Symposium
Obesity and Cancer: When Systemic Metabolism Meets Cell Metabolism
Sunday, March 31, 2019


Nina J. Chu, PhD
Postdoctoral Fellow
Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center


Advances in Organ Site Research
Advances in Pancreatic Cancer
Monday, April 1, 2019


Cosimo Commisso, PhD
Assistant Professor
Cancer Center Sanford Burnham
Prebys Medical Discovery Institute

Regulation of nutrient stress-induced macropinocytosis in pancreatic cancer
 
Special Session
NextGen Stars Spotlight 2: Site-Specific Cancers
Monday, April 1, 2019

Greg M. Delgoffe, PhD
Assistant Professor, Immunology
University of Pittsburgh

Reprogramming tumor microenvironment metabolism to improve immunotherapy
 
Major Symposium
Defining Systemic Tumor-host Communication in Cancer Progression and Therapy Responses
Monday, April 1, 2019

Ann-Kathrin Eisfeld, MD
Fellow, Physician-Scientist Training Program Hematology/Medical Oncology
Ohio State University

Revealing the molecular landscape and associated prognostic implications in patients with acute myeloid leukemia
 
Special Session
NextGen Stars Spotlight 1: Genetics and Immunology
Sunday, March 31, 2019


Andreana N. Holowatyj, PhD, MS
NIH/NHGRI T32 Ruth L. Kirschstein NRSA Postdoctoral Fellow, Genomic Medicine
Huntsman Cancer Institute, University of Utah

Multi-omics analysis reveals a distinct molecular phenotype in patients with young-onset colorectal cancer

Special Session
NextGen Stars Spotlight 2: Site-Specific Cancers
Monday, April 1, 2019


Benjamin Izar, MD, PhD
Clinical Fellow
Dana-Farber Cancer Institute

Development of therapeutic strategies by resolving the tumor ecosystem

Major Symposium
The Next Generation of Precision Cancer Medicine: Recognizing and Exploiting the Complexity
Monday, April 1, 2019


Michalina Janiszewska, PhD
Assistant Professor, Molecular Medicine
The Scripps Research Institute Florida

Divergent resistance mechanisms to HER2-targeted therapies in breast cancer

Special Session
NextGen Stars Spotlight 2: Site-Specific Cancers
Monday, April 1, 2019


Ashish A. Kulkarni, PhD
Assistant Professor, Chemical Engineering
University of Massachusetts Amherst

Immunotheranostic probes for monitoring cancer immunotherapy response

Advances in Diagnostics and Therapeutics
Molecular Imaging for Cancer Immunotherapy
Tuesday, April 2, 2019


Yiting Lim, PhD
Postdoctoral Fellow
Fred Hutchinson Cancer Research Center

Functional analysis of 5’ UTR mutations in prostate cancer reveal dynamic regulation of clinically relevant gene networks

Special Session
NextGen Stars Spotlight 2: Site-Specific Cancers
Monday, April 1, 2019


David Liu, MD
Fellow
Dana-Farber Cancer Institute/Massachusetts General Hospital

Dissecting genomic correlates of response and resistance to chemotherapy in bladder cancer through clinical computational oncology

Major Symposium
Convergence of Artificial Intelligence, Big Data, and Prediction in Cancer
Tuesday, April 2, 2019


Faruk Mohammed, MS
Graduate Student
Ahmadu Bello University

Prostate cancer risk factors and genomic characterization in West African Black men using epidemiology and NGS: Findings from the CaPTC

Advances in the Science of Cancer Health Disparities
The Science of Cancer Health Disparities
Sunday, March 31, 2019


Tamara Ouspenskaia, PhD
Postdoctoral Fellow
Broad Institute of MIT and Harvard

Expanding the immunopeptidome with ribosome profiling

Special Session
NextGen Stars Spotlight 1: Genetics and Immunology
Sunday, March 31, 2019


Ferdinandos Skoulidis, MD, PhD
Assistant Professor, Thoracic Head and Neck Medical Oncology
The University of Texas MD Anderson Cancer Center

Inactivating STK11/LKB1 genomic alterations are a major driver of primary resistance to PD-1 axis blockade in non-squamous non-small cell lung cancer

Major Symposium
Dharma Master Jiantai Symposium in Targeted Therapy: Systematic Elucidation of Nononcogene Targets
Monday, April 1, 2019


Liuqing Yang, PhD
Assistant Professor, Department of Molecular and Cellular Oncology
The University of Texas MD Anderson Cancer Center

Long noncoding RNA-directed antigenicity loss suppresses immunosurveillance

Special Session
NextGen Stars Spotlight 1: Genetics and Immunology
Sunday, March 31, 2019


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View the abstracts of the NextGen Stars' presentations from the AACR Annual Meeting 2018:

Samuel F. Bakhoum, MD, PhD
Holman Research Fellow, Department of Radiation Oncology
Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine, New York, New York

Chromosomal instability promotes metastasis through a cytosolic DNA response

Major Symposium
Tumor-Host Interactions Regulating Cancer Metastasis
Tuesday, April 17, 2018


Stacey D. Finley, PhD
Assistant Professor, Department of Biomedical Engineering
University of Southern California, Los Angeles, California

Effects of altering receptor structure in CAR T cells: Predictions from an experimentally-validated systems biology model

Major Symposium
Translational Applications of Systems Biology
Sunday, April 15, 2018


Michael E. Fraser, PhD
Director, Prostate Cancer Research
Ontario Institute for Cancer Research, Toronto, Ontario, Canada

The clinico-genomics of localized, non-indolent prostate cancer: the CPC-GENE experience

Recent Advances in Prevention and Interception Research
Precision Prevention and Early Detection of Cancer
Wednesday, April 18, 2018


Yejing Ge, PhD
Postdoctoral Fellow, Laboratory of Mammalian Cell Biology & Development
The Rockefeller University, New York, New York

Functional interrogation of cell plasticity in cancer

Major Symposium
Genetics and Epigenetics in Tumor and TME: Origins, Evolution and Drug Resistance
Tuesday, April 17, 2018


Willy Hugo, PhD
Adjunct Assistant Professor
University of California Los Angeles, Los Angeles, California

Immune Evasion mechanisms in melanoma resistant to targeted- and/or immunotherapy

Major Symposium
Genomic/Functional Screens to Predict Response/Resistance to Immunotherapy
Tuesday, April 17, 2018


Ciara Metcalfe, PhD
Scientist, Translational Oncology
Genentech, South San Francisco, California

Not all “SERDs” are equal: Context-independent ER degradation and full ER antagonism define the next generation of ER therapeutics

Major Symposium
Optimizing Response to Endocrine Therapy
Tuesday, April 17, 2018


A. Hunter Shain, PhD
Assistant Professor, Dermatology
University of California San Francisco, San Francisco, California

Genomic and transcriptomic analysis reveals incremental disruption of key signaling pathways during melanoma evolution

Recent Advances in Diagnostics and Therapeutics Research
Recent Advances of Single-Cell Genomics in Cancer Research
Wednesday, April 18, 2018