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FINDING CURES TOGETHER<sup>SM</sup>

Evolutionary Dynamics in Carcinogenesis and Response to Therapy

March 12-15, 2020
Westin Denver Downtown
Denver, Colorado

Abstract Submission and Award Application Deadline: Tuesday, Dec. 31, 2019
Advance Registration Deadline: Monday, Feb. 3, 2020

Conference Cochairs
James DeGregori, University of Colorado, Aurora, Colorado
Marco Gerlinger, The Institute of Cancer Research, London, United Kingdom
Robert Gillies, Moffitt Cancer Center, Tampa, Florida
Andriy Marusyk, Moffitt Cancer Center, Tampa, Florida

This will mark the first AACR Special Conference on evolutionary dynamics in cancer and how these processes contribute to therapy resistance and failure. Tumors are genetically diverse and complex ecosystems that evolve in response to selection pressures from its environment. The aim for this AACR Special Conference is to move away from the simplistic view of cancer evolution as a merely genetic phenomenon and to discuss instead how microenvironmental, immune cell, genetic and epigenetic heterogeneity interact and evolve and how this influences cancer progression and therapy success or failure. By promoting the exchange of novel ideas and information between basic scientists, physicians, and other health professionals, this inaugural conference will enhance the understanding of cancer evolution and make progress toward treatment paradigms that limit therapy resistance.

Continuing Medical Education Activity AMA PRA Category 1 CreditsTM available