TME Election Results

Congratulations to Sheila A. Stewart, DPhil, TME Chairperson-elect 2018-2019

Our thanks to Theresa A. Guise, MD, and Sheila A. Stewart, DPhil, for standing for election, and to the TME membership for participating in the election. We congratulate Dr. Stewart on being elected as TME chairperson-elect. Dr. Stewart will assume the office of chairperson-elect at the AACR Annual Meeting 2018, April 14-18, 2018, in Chicago, Illinois.

Sheila A. Stewart, DPhil
Division of Cell Biology and Physiology
Washington University in St. Louis
St. Louis, Missouri

Other Positions Currently Held

2015-present, Associate Director for Basic Science, Siteman Cancer Center, Washington University at St. Louis, St. Louis, Missouri

PhD, University of California, Los Angeles, Los Angeles, California

Research Interests:
My research is focused on understanding how age-related changes in the microenviornment contribute to tumorigenesis. We use a multidisciplinary approach to ask how senescent stromal cells impact the local immune response in both the primary and metastatic sites. In addition, because senescent stromal cells accumlate within the pre-metastatic site with age, we are also asking how senescent cells alter this niche within the bone and impact metastasis. Finally, we are also asking what impact and aging stromal compartment has on tumor cell dormancy.

Proposed Goals:
My goal as chairperson-elect of the Tumor Microenvironment Working Group (TME) is to build on the success of the past leaders and expand the visibility of the TME working group both within the AACR and beyond to sister organizations and funding agencies throughout the world. Further, I will work to increase the visibility of the group and the importance of the microenvironment to industry and create partnerships to increase discovery of novel therapeutics that target the microenvironment. I will accomplish these goals by lobbying for increased representation for the working group at national meetings as well as smaller meetings both at home and abroad. Importantly, I will work to expand the definition of the microenvironment to include not only cells and the structural components within the local microenvironment, but also those that operate at the systemic level to influence all steps in the tumorigenic process. In addition, I will work to increase outreach to young investigators by providing them with opportunities to participate in meetings and working to develop a mentorship program that attracts new investigators into this vibrant area of research.