Vincent T. DeVita Jr., MD

Vincent T. DeVita Jr., MD
Amy and Joseph Perella Professor of Medicine, Yale Cancer Center and Professor of Epidemiology and Public Health, Yale Medical School, New Haven, Connecticut

Vincent T. DeVita Jr., MD | Class of 2014

A pioneer in oncology research, Dr. DeVita is internationally recognized for developing combinatorial anti-cancer therapy regimens for Hodgkin’s disease and diffuse large cell lymphoma. With colleagues at the National Cancer Institute (NCI) in the 1960s, he developed the four-drug combination therapy of mechlorethamine, oncovin, procarbazine, and prednisone (MOPP), which resulted in drastically improved cure rates for advanced Hodgkin’s disease from nearly zero to over 70 percent. The administration of MOPP was the first instance whereby chemotherapy was utilized to essentially cure an advanced adult cancer in a major organ system, a treatment option that continues to be used as a second-line treatment.

Dr. DeVita also contributed to the development of the combination therapy, cyclophosphamide, methotrexate, and fluorouracil (CMF) for breast cancer. After his son Ted was diagnosed with aplastic anemia, Dr. DeVita began research devoted to understanding the genetic and molecular basis of immunologically related diseases. Ted’s life was immortalized in the TV movie, The Boy in the Plastic Bubble.

He was named director of the NCI in 1980 and served until 1988. In 2000, he was appointed chair of the National Cancer Legislative Advisory Committee. This Senate advisory committee worked with the National Dialogue on Cancer, spearheaded by President George W. Bush, to make recommendations for the revision and modernization the National Cancer Act of 1971. Dr. DeVita is one of three editors of Cancer: Principles and Practice of Oncology, long recognized as one of the world’s leading oncology references.

Career Highlights

2013  Giants of Cancer Care Award, OncLive
2012  President, American Cancer Society, Volunteer Board of Directors
2009  Distinguished Medical Science Award, Friends of the National Library of Medicine
2007  FREDDIE, International Health & Medical Media Award
2002  Elected Member, European Academy of Sciences
2000  Saul Rosenberg Research Award, Lymphoma Research Foundation of America
1999  Mary Waterman Award, Breast Cancer Alliance
1998  Commendatore of the Italian Republic Order of Merit
1990  Armand Hammer Prize for Cancer Research
1988  Pezcoller Foundation-AACR International Award for Cancer Research
1986  AACR-Richard and Hinda Rosenthal Award
1985  Elected Member, Institute of Medicine
1985  Pierluigi Nervi Award for Cancer Research
1976-1979  Board of Directors, AACR
1972  Albert Lasker Basic Medical Research Award
1961  MD, George Washington University School of Medicine