​In Memoriam: ​Denise A. Chan, PhD

Denise A. Chan

4/4/1977 - 10/24/2​014)
Member since 2010

​​Denise Chan, PhD, principal investigator and assistant professor in the Department of Radiation Oncology at the University of California, San Francisco (UCSF), died Oct. 24,2014. Chan was a member of the AACR since 2010.

Born in Los Angeles, April 4, 1977, Chan received her doctorate from Stanford University in Stanford, California, after  completing  her  bachelor’s  degree  from  the  University of California, Los Angeles,in 1999.

Chan’s doctoral research focused on the  role  of  prolylhydroxylation  in  the  coordinated regulation  of  the  oxygen-dependent  degradation  domains  of  hypoxia-inducible  factor.

In 2004,  she  received  the Malcolm  A.  Bagshaw  Award  by  Stanford  University  School  of Medicine in  recognition  of  her  novel  approach to understanding the structural basis of oxygen sensing in mammalian cells.

She was also awarded an individual Ruth L. Kirschstein National  Service  Postdoctoral  Fellowship  from  the  National  Cancer  Institute for 2004 through 2009. During this time, she published 17 papers, including a seminal piece of work about the recruitment of tumor vasculature to solid tumors.

In 2009, Chan joined UCSF, and worked on several projects during her time there, including research  into  the  effects  of  hypoxia  on  estrogen  receptors in breast  cancer  and  synthetic lethality screening for new therapeutics.