Da Costa Professor of Biology, Department of Biological Sciences, Herbert and Florence Irving Institute for Cancer Dynamics, Columbia University,
New York, New York
For discovering that p53 is a DNA sequence-dependent transcriptional regulator and when mutated, possesses novel oncogenic functions, for identifying p53 and Mdm2 stress signal-induced regulatory mechanisms, and for revealing novel pathways by which p53 functions to suppress cell growth and promote cell death.
The AACR-G.H.A. Clowes Award for Outstanding Basic Cancer Research was established by the AACR and Eli Lilly and Co. in 1961 to honor Dr. G.H.A. Clowes, who was a founding member of the AACR and a research director at Eli Lilly. The award is intended to recognize an individual who has made outstanding recent accomplishments in basic cancer research. To learn more, please visit the press release.