Dafna Bar-Sagi, PhD, FAACR

Dafna Bar-Sagi, PhD, FAACR

NYU Langone Medical Center

Research Interests

Signal transduction pathways; role of Ras proteins in cancer initiation and progression; development of cell- and animal-based models in the study of inflammation and immunity in Ras-driven tumorigenesis; characterization of feedback mechanisms that control the functional output of the Ras signaling axis; utilization of chemical biology approaches to identify new modalities for therapeutic targeting; oncogene function in pancreatic cancer.

Current Affiliations

Saul J. Farber Professor, Department of Biochemistry and Molecular Pharmacology; Senior Vice President and Vice Dean for Science and Chief Scientific Officer; Professor, Department of Medicine, New York University School of Medicine, New York, New York.

Previous Positions

Chair, Department of Biochemistry, New York University School of Medicine (2006-2011), New York, New York; Chair (2003-2006), Professor (1998-2002), and Associate Professor (1995-1998), Department of Molecular Genetics and Microbiology, State University of New York, Stony Brook, New York; Senior Staff Investigator (1989-1995) and Staff Investigator (1987-1989), Cold Spring Harbor Laboratory, Cold Spring Harbor, New York.

Postdoctoral Training

Postdoctoral Fellow, Cold Spring Harbor Laboratory (1984-1987), Cold Spring Harbor, New York.

Selected AACR Service, Honors, and Awards

Elected Fellow, AACR Academy (2019); Cochair, Special Conference, “Pancreatic Cancer: Advances in Science & Clinical Care” (2019); Recipient, AACR Charlotte Friend Memorial Lectureship Award (2018); Member, Science Education and Career Advancement Committee (2018-2021); Member, Laboratory Research Awards Committee (2018-2020, 2006-2008); Member, Board of Directors (2016-2019); Member, Publications Committee (2016-2019); Member, AACR NextGen Grants for Transformative Cancer Research Committee (2016-2018); Chair, Pancreatic Cancer Action Network-AACR Pathway to Leadership Grant Scientific Review Committee (2016-2017); Member, Stand Up To Cancer Innovative Research Grants Committee (2015-2016); Cochair, Special Conference, “Pancreatic Cancer: Innovations in Research and Treatment” (2014); Cochair, Special Conference, “Ras Oncogenes: From Biology to Therapy” (2014); Member, Cancer Immunology Working Group (2013-present); Member, Tumor Microenvironment Working Group (2013-present); Member, Tellers Committee (2013-2014); Cochair, Special Conference, “Pancreatic Cancer: Progress and Challenges” (2012); Member, Special Conferences Committee (2011-2014); Chair, Pancreatic Cancer Action Network-AACR Pilot Grants Scientific Review Committee (2009); Chair (2009) and Member (2006-2008), Research Grants Review Committee; Cochair (2008, 2011) and Member (2010, 2013), Annual Meeting Program Committee.

Selected Non-AACR Service, Honors, and Awards

Keynote Lecturer, European Society for Medical Oncology Conference, Barcelona, Spain (2019); Distinguished Lecturer in Cancer Biology, The University of Texas MD Anderson Cancer Center (2019); Distinguished Lecturer in Cancer Research, The Wistar Institute (2019); Keynote Speaker, Cold Spring Harbor Laboratory Meeting “Biology of Cancer: Microenvironment and Metastasis” (2019); Chair (2018-2021) and Member (2013-present), National Cancer Institute Board of Scientific Advisors; Speaker, Translational Research Perspectives in Pancreatic Cancer, American Medical Center Hospital (JCI) Sheba Medical Center, Israel (2018); Krakoff Family Lecture Speaker, Dana-Farber Cancer Institute (2016); Recipient, Julia Hudson Freund Lecture, Washington University School of Medicine, St. Louis (2015); Recipient, Lola & John Grace Distinguished Lectureship in Cancer Research, Swiss Institute for Experimental Cancer Research, Lausanne (2013); Chair (2008-2010) and Member (2006-present), Scientific Advisory Board, Pancreatic Cancer Action Network; Member, Scientific Review Board, Starr Cancer Consortium (2010-2015); Member, NIH Review Panel for Director’s New Innovator Awards (2007-2008); Member, Board of Scientific Counselors, National Cancer Institute (2006-2011); Recipient, National Cancer Institute MERIT Award (1996-2006).


PhD, Cell Biology, State University of New York at Stony Brook, New York (1984); MSc (1980) and BSc (1976), Biochemistry, Bar-Ilan University, Israel.