Ira Mellman, PhD, FAACR
AACR-Cancer Research Institute Lloyd J. Old Award in Cancer Immunology

Ira Mellman, PhD, FAACR

Vice President of Cancer Immunology, Genentech
Adjunct Professor, University of California, San Francisco
South San Francisco, California

For paramount advances in cell biology including the discovery of endosomes, for applying these insights to understanding the immune response and demonstrating how dendritic cell maturation regulates the balance between immunity and tolerance. He has elucidated the mechanism of the PD-L1/PD-1 signaling pathway and the conceptualization of the Cancer Immunity Cycle, bringing atezolizumab to the clinic, and overseeing the discovery and development of iNeST-RNA, tiragolumab (anti-TIGIT), cobimetinib, mosunetuzumab, and a variety of other therapeutics currently in earlier stages of clinical investigation.

The AACR-Cancer Research Institute Lloyd J. Old Award in Cancer Immunology recognizes an active scientist whose outstanding and innovative research has made a major impact on the cancer field and has the potential to stimulate new directions in cancer immunology.

To learn more, please visit the press release.

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