Kevan M. Shokat, PhD
AACR Award for Outstanding Achievement in Chemistry in Cancer Research

Kevan M. Shokat, PhD

Professor and Chair, Department of Cellular and Molecular Pharmacology, UC San Francisco
Professor, Department of Chemistry, UC Berkeley
Investigator, Howard Hughes Medical Institute
San Francisco, California

For his seminal discoveries in the field of chemical genetics, solving the fundamental selectivity challenge for protein kinases by engineering a unique ATP binding pocket and matched chemical inhibitor to exploit and selectively target individual protein kinase. His breakthrough discoveries include the development of the first covalent inhibitors of KRAS G12C leading to clinical trials to target a once thought undruggable oncogene.

The AACR Award for Outstanding Achievement in Chemistry in Cancer Research was established by the AACR and its Chemistry in Cancer Research Working Group in 2007, through the initial support of GlaxoSmithKline, to recognize the importance of chemistry to advancements in cancer research. The award is intended to recognize outstanding, novel, and significant chemistry research that has led to important contributions in basic cancer research, translational cancer research, cancer diagnosis, the prevention of cancer, or the treatment of patients with cancer. To learn more, please visit the press release.

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